THz spectroscopy is important for the study of ion channels because it directly addresses the low frequency collective motions relevant for their function. Here we used THz spectroscopy to investigate the inhibition of the epithelial sodium channel (...
Spectroscopy in the terahertz (THz) band has been discussed as a promising tool for identifying substances such as mold in food, narcotics, or explosive materials. Other than the technological limitations, the most important difficulty is the presenc...
A review is provided of sources and detectors that can be employed in the THz range before the description of an opto-electronic source of monochromatic THz radiation. The realized spectrometer has been applied to gas phase spectroscopy. Air-broadeni...
We discuss an effective tool for the detection and identification of substances in ternary mixtures with similar spectral properties using a broadband reflected THz signal. Nowadays, this is an urgent problem; its effective solution is still far off....
The increase of device lifetime and reliability of THz photomixers will play an essential role in their possible future application. Therefore, their optimal work conditions/operation range, i.e., the maximal incident optical power should be experime...
This paper describes a process to obtain magnetite functionalized with carboxymethylcellulose via coprecipitation by means of a preliminary stabilization of magnetite in citric acid. The magnetite assemblies successfully passed in vitro and in vivo t...
Polymer composites containing nanocarbon fillers are under intensive investigation worldwide due to their remarkable electromagnetic properties distinguished not only by components as such, but the distribution and interaction of the fillers inside t...
The electromagnetic characterisation of different materials for the inner wall coating of beam pipes is a long-standing problem in accelerator physics, regardless the purpose they are used for, since their presence may affect in an unpredictable way...
We present an investigation of the thermal damage threshold of passivated Bi2Se3 films upon laser illumination, with a focus on their employment in terahertz (THz) spectroscopic applications. Passivation was achieved by depositing a thin 3 nm Al capp...
Nowadays, physicochemical methods of analysis are used in medical diagnostics. One can identify metabolites characteristic of a particular disease. The compilation of a metabolic profile will facilitate the diagnosis of diseases, evaluate their stage...
Recently we have demonstrated a new nonlinear optical effect in the THz interval of frequencies. The latter is based on the use of femtosecond optical pulses and intense, sub-ps, broadband terahertz (THz) pulses to generate a THz-optical four- and fi...
We considered one-dimensional quantum chains of two-level Fermi particles coupled via the tunneling driven both by ac and dc fields in the regimes of strong and ultrastrong coupling. The frequency of ac field is matched with the frequency of the quan...
We present a fiber coupled transceiver head for terahertz (THz) time-domain reflection measurements. The monolithically integrated transceiver chip is based on iron (Fe) doped In0.53Ga0.47As (InGaAs:Fe) grown by molecular beam epitaxy. Due to its ult...
We have studied the spectral resolution influence on the accuracy of the substance detection and identification at using a broadband THz pulse measured under real conditions (at a distance of more than 3 m from a THz emitter in ambient air with a rel...
Ultrafast pulsed lasers find application in a range of spectroscopy and sensing techniques including laser induced breakdown spectroscopy (LIBS), coherent Raman spectroscopy, and terahertz (THz) spectroscopy. Whether based on absorption or emission p...
Exhaled air contains volatile molecular compounds of endogenous origin, being products of current metabolic pathways. It can be used for medical express diagnostics through control of these compounds in the patient’s breath using molecular abso...
The shipping industry is a major contributor to global greenhouse gas (GHG) emissions, which is why it is important to optimize every aspect of the efficiency of ocean-going vessels. This includes the antifouling paint that ensures hydrodynamic effic...
In this study, we developed a rapid nondestructive tool for testing rust spread in a metal covered by a paint layer by using a THz time-domain spectroscopy system at a speed of 100 Hz/pixel. Time-of-flight imaging helps identify rust formation by exc...
Approximately 50 years of inelastic scattering studies of noble gases are reviewed to illustrate the main advances achieved in the understanding of the THz dynamics of simple systems. The gradual departure of the spectral shape from the hydrodynamic...
We demonstrate the use of a novel, integrated THz system to obtain time-domain signals for spectroscopy in the 0.1–1.4 THz range. The system employs THz generation in a photomixing antenna excited by a broadband amplified spontaneous emission (...
Cocrystallisation can enhance the solubility and bioavailability of active pharmaceutical ingredients (APIs); this method may be applied to improve the availability of materials that were previously considered unsuitable. Terahertz (THz) spectroscopy...
The demand for rapid and accurate identification of microorganisms is growing due to considerable importance in all areas related to public health and safety. Here, we demonstrate a rapid and label-free strategy for the identification of microorganis...
We propose the concept of high-power THz radiation sources based on five-fold frequency multiplication in gyrotrons intended for plasma applications. The efficient excitation at the 5th cyclotron harmonic is due to the specific property of the eigenm...
Attenuated total reflection time-domain spectroscopy (ATR-TDS) in the terahertz regime was employed to investigate the dielectric response of water–acetone mixtures over the full molar concentration range. The ATR configuration enabled stable m...
Organometallic lead bromide and iodide perovskite single crystals (PSCs) are potential candidates for terahertz applications. Herein, we performed terahertz time-domain spectroscopy (THz-TDS) in the frequency range of 0.1–3.0 THz on different t...
Background: The aqueous solubility of indomethacin, a poorly water-soluble anti-inflammatory drug, was enhanced by co-crystallization with co-formers. The co-crystals were characterized and compared by an X-ray diffraction (XRD) analysis, terahertz (...
Due to its high sensitivity and because it does not rely on the magneto-optical response, terahertz (THz) emission spectroscopy has been used as a powerful time-resolved tool for investigating ultrafast demagnetization and spin current dynamics in na...
An ability of lensless titanium-based antenna coupled microbolometers (Ti-
Gasoline engine oil (SAE 5W-20) was subjected to thermal oxidization (TO) for four periods of time (0 h, 48 h, 96 h and 144 h) and exposed to THz-time domain spectroscopy (TDS) measurement. Error contributions from various error sources, such as repe...
Organic crystals with second-order optical nonlinearity feature very high and ultra-fast optical nonlinearities and are therefore attractive for various photonics applications. During the last decade, they have been found particularly attractive for...
Terahertz (THz) time-domain spectroscopy (TDS) is a powerful tool used to characterize the surface/interface of materials, and semiconductor/metal interfaces can generate THz emission through ultrafast optical excitation, which can be further improve...
We demonstrate that the conductivity of graphene on thin-film polymer substrates can be accurately determined by reflection-mode air-plasma-based THz time-domain spectroscopy (THz-TDS). The phase uncertainty issue associated with reflection measureme...
Surfaces of semiconducting materials excited by femtosecond laser pulses emit electromagnetic waves in the terahertz (THz) frequency range, which by definition is the 0.1–10 THz region. The nature of terahertz radiation pulses is, in the majori...
We investigate the possibility of sensing opioid drugs, such as fentanyl, by their THz electromagnetic signatures. The methods include both computer modeling and experiments. Molecular dynamics simulations predict that fentanyl should display THz res...
Terahertz time-domain spectroscopy is a useful technique for determining some physical characteristics of materials, and is based on selective frequency absorption of a broad-spectrum electromagnetic pulse. In order to investigate the potential of th...
To detect and differentiate two essential amino acids (L-Valine and L-Phenylalanine) in the human body, a novel asymmetrically folded dual-aperture metal ring terahertz metasurface sensor was designed. A solvent mixture of water and glycerol with a v...
The pharmaceutical co-crystal has attracted increasing interest due to the improvement of physicochemical properties of active pharmaceutical ingredients. The characterization of pharmaceutical co-crystal is an integral part of the pharmaceutical fie...
We report on the room-temperature experimental measurement of THz absorption signatures in aqueous, double-stranded nucleic acid solutions confined to the submicron silica channels on fused quartz substrates using THz frequency-domain (photomixing) s...
TeraFERMI is the THz beamline at the FERMI free-electron-laser facility in Trieste (Italy). It uses superradiant Coherent Transition Radiation emission to produce THz pulses of 10 to 100
Water content of the skin is an important parameter for controlling the penetration rate of chemicals through the skin barrier; therefore, for transdermal patches designed for drug delivery to be successful, the effects of the patches on the water co...
The co-crystallization of active pharmaceutical ingredients (APIs) has received increasing attention due to the modulation of the relative physicochemical properties of APIs such as low solubility, weak permeability and relatively inferior oral bioav...
We report the performance of a graphene-enhanced THz grating fabricated by depositing a gold layer on the femtosecond micromachined SiO2 substrate. The morphology of the gold plated patterned substrate was studied by scanning electron microscopy (SEM...
Low efficiency of the standard THz TDS method of the detection and identification of substances based on a comparison of the spectrum for the signal under investigation with a standard signal spectrum is demonstrated using the physical experiments co...
This article proposes a new method for sensing THz waves that can allow electric field measurements traceable to the International System of Units and to the fundamental physical constants by using the comparison between precision measurements with c...
In this work, the optical parameters of a 550 μm thick deuterated triglycine sulfate (DTGS) crystal in the range of 0.3–1.5 THz were investigated in low and high fields by time-domain spectroscopy. The X and Z axes of the refractive index el...
Simultaneous emission of the THz wave and hard X-ray from thin water free-flow was induced by the irradiation of tightly-focused femtosecond laser pulses (35 fs, 800 nm, 500 Hz) in air. Intensity measurements of the THz wave and X-ray were carried ou...
In this work, the prospects of integrating terahertz (THz) time-domain spectroscopy (TDS) within polymer-based microfluidic platforms are investigated. The work considers platforms based upon the polar polymers polyethylene terephthalate (PET), polyc...
Sugar substitutes, which generally refer to a class of food additives, mostly have vibration frequencies within the terahertz (THz) band. Therefore, THz technology can be used to analyze their molecular properties. To understand the characteristics o...
THz time-domain spectroscopy (TDS) is a promising tool for quality control purposes in industrial applications, but the high cost and the relatively large laser sources still make it difficult to use the full potential of the technology for a decent...
Coffee bean sorting is currently based primarily on visual appearance and near-infrared techniques that probe the bean’s skin. However, sorting based on compositional differences has significant potential to optimize the roasting process. We pr...
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