281 Results Found

Breast cancer is the leading cause of cancer-related death in women, and despite advances in preventive screening as well as in molecular classification, many patients still do not benefit from existing therapies, highlighting the importance of ident...

Development requires the careful orchestration of several biological events in order to create any structure and, eventually, to build an entire organism. On the other hand, the fate transformation of terminally differentiated cells is a consequence...

Prolonged hyperinsulinemic hypoglycemia in infancy can result in developmental sequelae. A mutation in the paired box-6 gene (PAX6) has been reported to cause disorders in oculogenesis and neurogenesis. A limited number of cases of diabetes mellitus...

Ultraviolet irradiation-induced hyperpigmentation of the skin is associated with excessive melanin production in melanocytes. Tyrosinase (TYR) is a key enzyme catalyzing the rate-limiting step in melanogenesis. TYR expression is controlled by microph...

In order to improve the housing conditions of stallions in individual boxes, we tested a so-called “social box” allowing increased physical contact between neighbouring horses. This study investigated whether housing stallions in social b...

Nontoxic natural products useful in skin care cosmetics are of considerable interest. Tyrosinase is a rate-limiting enzyme for which its inhibitor is useful in developing whitening cosmetics. Pyracantha koidzumii (Hayata) Rehder is an endemic species...

Paired box gene 3 (Pax3) and cAMP responsive element-binding protein (CREB) directly interact with the cis-acting elements on the promoter of microphthalmia-associated transcription factor isoform M (MITF-M) for transcriptional activation in the mela...

Paired box (PAX) genes encode a family of nine transcription factors that function as master regulators of embryogenesis, organogenesis, and lineage specification. Their tightly regulated spatial and temporal expression is essential for the developme...

The considerable post-traumatic brain recovery in fishes makes them a useful model for studying the mechanisms that provide reparative neurogenesis, which is poorly represented in mammals. After a mechanical injury to the telencephalon in adult fish,...

It is still challenging to effectively detect ship objects in optical remote-sensing images with complex backgrounds. Many current CNN-based one-stage and two-stage detection methods usually first predefine a series of anchors with various scales, as...

Staphylococcus aureus (S. aureus) is one of the most prevalent contagious bacterial pathogens causing clinical bovine mastitis. In the present study, plate (A), which consists of 80 compounds (40 drug-like and 40 probe-like), was assessed from the Ma...

Prohibitin (PHB) and paired box 2 (PAX2) are associated with the development of renal interstitial fibrosis (RIF). This study was performed to investigate whether or not the PHB could regulate the PAX2 gene expression in unilateral ureteral obstructi...

Mediastinal cysts are typically of bronchogenic, thymic or neurenteric origin, but may also represent oesophageal duplication. Posterior paravertebral mediastinal Müllerian cysts of undetermined pathogenesis are very rare occurrences. The first case...

The relationship of PAX1/JAM3 methylation as well as HPV viral load (VL) with cervical lesions has been reported, but their role in persistent HPV infection without cervical high-grade lesions has not been fully elucidated. A total of 231 females dia...

Length determination is a fundamental problem in biology and chemistry. Numerous proteins measure distances on linear biopolymers to exert effects with remarkable spatial precision. Recently, ruler-like devices made of noncoding RNAs have been struct...

Somatostatin is a peptide hormone, which most commonly is produced by endocrine cells and the central nervous system. In mammals, somatostatin originates from pre-prosomatostatin and is processed to a shorter form, i.e., somatostatin-14, and a longer...

Retinoids are essential in balancing proliferation, differentiation and apoptosis, and they exert their effects through retinoic acid receptors (RARs) and retinoid X receptors (RXRs). RARβ is a tumor-suppressor gene silenced by epigenetic mechan...

Complex RNA–RNA interactions are increasingly known to play key roles in numerous biological processes from gene expression control to ribonucleoprotein granule formation. By contrast, the nature of these interactions and characteristics of the...

We present a detailed analysis of the effect of quantum loss and decoherence in the Bell-CHSH scenario. Adopting a device-independent approach, we study the change in the bipartite conditional probability distribution, i.e., the behavior of the reali...

When selecting a habitat, it is optimal for organisms to choose one that maximizes reproductive success through access to high-quality resources, particularly in species that engage in parental care. However, organisms may inadvertently select a habi...

For the map building of unknown indoor environment, compared with single robot, multi-robot collaborative mapping has higher efficiency. Map merging is one of the fundamental problems in multi-robot collaborative mapping. However, in the process of g...

In this study, we propose a digital domain TDI-CMOS dynamic imaging method based on minimum search domain alignment, which consists of five steps: image-motion vector computation, image jitter estimation, feature pair matching, global displacement es...

In order to improve the performance in terms of detecting objects colliding in virtual reality, the ant colony algorithm was used to detect collisions. In the preliminary detection stage, the OBB bounding box and the spherical bounding box were used...

Racial/ethnic and sex concordance between patients and providers has been suggested as an important consideration in improving satisfaction and increasing health equity. We aimed to guide local efforts by understanding the relationship between satisf...

Historical opera houses in Italy have been the place for the development of a relevant part of the National musical tradition and their design is paired with a peculiar acoustical fingerprint. Due to its relevance this can be regarded as an intangibl...

The F-box family is one of the largest gene families in plants that regulate diverse life processes, including salt responses. However, the knowledge of the soybean F-box genes and their roles in salt tolerance remains limited. Here, we conducted a g...

The Advanced Encryption Standard (AES) symmetric encryption algorithm plays a crucial role in data encryption. To address the limitations of the fixed Substitution-box (S-box) and static key expansion strategy in AES. This paper proposes an improved...

The MADS-box gene family is one of the largest families in plants and plays an important roles in floral development. The MADS-box family includes the SRF-like domain and K-box domain. It is considered that the MADS-box gene family encodes a DNA-bind...

Sample entropy, an approximation of the Kolmogorov entropy, was proposed to characterize complexity of a time series, which is essentially defined as $-log(B/A)$, where B denotes the number of matched template pairs with length m and A denotes th...

MADS-box is a class of transcriptional regulators that are ubiquitous in plants and plays important roles in the process of plant growth and development. Identification and analysis of blueberry MADS-box genes can lay a foundation for their function...

Algebraic persistent fault analysis (APFA), which combines algebraic analysis with persistent fault attacks, brings new challenges to the security of lightweight block ciphers and has received widespread attention since its introduction. Threshold Im...

In domestic conditions, adult stallions are mostly housed individually in internal stables to reduce the risk of injuries during social interactions. Social deprivation in horses results in physiological stress and behavioural problems. The aim of th...

In order to overcome the drawbacks of expensive function evaluation in the practical reliability-based design optimization (RBDO) problem, researchers have proposed the black box-based RBDO method. The algorithm flow of the commonly employed RBDO met...

This paper examines the impacts of five planetary boundary layer (PBL) parameterization schemes paired with several compatible surface layer (SL) parameterization schemes in the Weather Research and Forecasting Model on wind hindcasts for resource as...

Proxy re-encryption (PRE) is a cryptographic primitive that extends public key encryption by allowing ciphertexts to be re-encrypted from one user to another without revealing information about the underlying plaintext. This makes it an essential pri...

MADS-box transcription factors play important roles in many organisms. These transcription factors are involved in processes such as the formation of the flower organ structure and the seed development of plants. Ginkgo biloba has two genome versions...

MIKC-type MADS-box transcription factors constitute one of the largest gene families in plants, playing pivotal roles in regulating plant growth and development, hormone signaling transduction, and responses to biotic and abiotic stresses. However, t...

Current machine intelligence metrics rely on a different philosophy, hindering their effective comparison. There is no standardization of what is machine intelligence and what should be measured to quantify it. In this study, we investigate the measu...

In the existing attribute-based encryption (ABE) scheme, the authority (i.e., private key generator (PKG)) is able to calculate and issue any user’s private key, which makes it completely trusted, which severely influences the applications of the ABE...

Normal processes of embryonic development and abnormal transformation to cancer have many parallels, and in fact many aberrant cancer cell capabilities are embryonic traits restored in a distorted, unorganized way. Some of these capabilities are cell...

Paired box 4 (Pax4) is a key transcription factor involved in the embryonic development of the pancreatic islets of Langerhans. Consisting of a conserved paired box domain and a homeodomain, this transcription factor plays an essential role in early...

Object tracking has gained importance in various applications especially in traffic monitoring, surveillance and security, people tracking, etc. Previous methods of multiobject tracking (MOT) carry out detections and perform object tracking. Although...

Achieving superior circularly polarized luminescence brightness (B_CPL) is an important subject and continuous challenge for chiroptical materials. Herein, by applying a binary molecular design for the synthesis of chiral organo-Tb³⁺ molecules, a nove...

The MADS-box gene family is a large family of transcription factors, and its members are widely distributed in the plant kingdom. Members of this family are well known to be crucial regulators of many biological processes and environmental responses....

Different charge treatment approaches are examined for cyclotide-induced plasma membrane disruption by lipid extraction studied with dissipative particle dynamics. A pure Coulomb approach with truncated forces tuned to avoid individual strong ion pai...

This paper presents datasets utilised for synthetic near-infrared (NIR) image generation and bounding-box level fruit detection systems. A high-quality dataset is one of the essential building blocks that can lead to success in model generalisation a...

To enhance the sliding tribological performance between PTFE and 40#steel (AISI 1040) under full film lubrication conditions, laser surface texturing (LST) technology was employed to prepare micro-dimples on the contact surfaces of 40# steel discs. T...

Ribulose bisphosphate carboxylase (RuBisCO) is the primary regulator of carbon fixation in the plant kingdom. Although the large subunit (RBCL) is the site of catalysis, RuBisCO efficiency is also influenced by the sequence divergence of the small su...

MADS-box genes constitute a large family of transcription factors that play important roles in plant growth and development. However, our understanding of MADS-box genes involved in anther development and male sterility in Salvia miltiorrhiza is stil...

Transcription factors play vital roles in the developmental processes of plants. The SQUAMOSA promoter binding protein (SBP) genes encode a family of plant-specific transcription factors and plays many crucial roles in plant development. In this stud...