12,638 Results Found

E3 ubiquitin-linked enzyme MARCH5, also known as membrane-associated circular finger 5, is an enzyme encoded by the human MARCH5 gene. The main objective of this study was to visualize the prognosis of MARCH5 in breast cancer and to determine the rel...

The molecular pathology of diseases seen from the mitochondrial axis has become more complex with the progression of research. A variety of factors, including the failure of mitochondrial dynamics and quality control, have made it extremely difficult...

The incidence of allergic diseases is increasing, and research on their epidemiology, pathophysiology, and the prevention of onset is urgently needed. The onset of allergic disease begins in infancy with atopic dermatitis and food allergy and develop...

The cellular transmembrane protein MARCH8 impedes the incorporation of various viral envelope glycoproteins, such as the HIV-1 envelope glycoprotein (Env) and vesicular stomatitis virus G-glycoprotein (VSV-G), into virions by downregulating them from...

Recent evidence showed that the postulated linear progression of the atopic march, from atopic dermatitis to food and respiratory allergies, does not capture the heterogeneity of allergic phenotypes, which are influenced by complex interactions betwe...

This paper aims to implement histogram pyramids with marching cubes method for 3D medical volumetric rendering. The histogram pyramids are used for feature extraction by segmenting the image into the hierarchical order like the pyramid shape. The his...

The atopic march encompasses a sequence of allergic conditions, including atopic dermatitis, food allergy, allergic rhinitis, and asthma, that frequently develop in a sequential pattern within the same individual. It was introduced as a conceptual fr...

Ebola virus (EBOV) glycoprotein (GP) is a class I fusion protein whose maturation is dependent on furin-mediated processing. EBOV-GP is heavily glycosylated, with glycans constituting ~50% of its molecular mass. Compared with 15 N-linked glycosylatio...

This paper addresses the problem of describing the complex linked coupling faults of memory devices and formulating the necessary and sufficient conditions for their detection. The main contribution of the proposed approach is based on using a new fo...

Objectives: (1) To measure sound exposures of marching band and non-marching band students during a football game, (2) to compare these to sound level dose limits set by NIOSH, and (3) to assess the perceptions of marching band students about their h...

Protein stability is largely regulated by post-translational modifications, such as ubiquitination, which is mediated by ubiquitin-activating enzyme E1, ubiquitin-conjugating enzyme E2, and ubiquitin ligase E3 with substrate specificity. Membrane-ass...

Introduction: The term allergic march has been used to describe natural evolution of the atopic disease in children, accompanied by the change in organ manifestation with time. The aim of the study was to analyze the role of the cellular components o...

In this paper, we present a multi-domain implicit surface reconstruction algorithm for geological modeling based on the labeling of voxel points. The improved algorithm sets a label for each voxel point to represent the type of its geological domain...

The association between pollen food allergy syndrome (PFAS) and allergic march remains unclear. In this prospective cohort study of the general population in Tokyo (T-Child Study), we found that sensitization to Cry j 1 and Fel d 1 at ages 5 and 9 ye...

In this paper, we explore a new approach, a two-step surface reconstruction method to extract the target isosurface from a given implicit function efficiently. Our main contribution is that we improve the surface reconstruction process by acceleratin...

In this paper, we present the application of Entrepreneurial Separation to Transfer Technologies from federally funded research and the difficulties associated with the transfer of intellectual property. With the increased threat (call) by the govern...

Numerous host factors function as intrinsic antiviral effectors to attenuate viral replication. MARCH8 is an E3 ubiquitin ligase that has been identified as a host restriction factor that inhibits the replication of various viruses. This study elucid...

The MARCH family of RING-finger E3 ubiquitin ligases comprise 11 members that have been reported to play a variety of roles in the downregulation of cell-surface proteins involved in adaptive immunity. The RING-CH domain of MARCH proteins is thought...

Marching modulus phenomena are often observed in silica-reinforced solution styrene–butadiene rubber/butadiene rubber (S-SBR/BR) tire tread compounds. When such a situation happens, it is difficult to determine the optimum curing time, and as a...

The advancement of robotics in recent years has driven the growth of robotic applications for more complex tasks requiring manipulation capabilities. Recent works have focused on adapting learning methods to manipulation applications which are stocha...

Allergic diseases consist of improper inflammatory reactions to antigens and are currently an important healthcare concern, especially considering their increasing worldwide development in recent decades. The “atopic march” defines the pa...

This paper presents a study on the evolution of extreme temperatures in the Marche region, Central Italy. To this end, a complete dataset compiled using data collected from available thermometric stations over the years 1957–2019 based on minim...

Finding efficient and accurate solution methods for nonlinear equilibrium equations is a challenging task. This is the case of systems with friction-induced nonlinearities, e.g., friction-damped turbomachinery assemblies and automotive applications s...

The overexpression of adenosine triphosphate (ATP)-binding cassette (ABC) subfamily B member 1 (ABCB1; P-glycoprotein; MDR1) in some types of cancer cells is one of the mechanisms responsible for the development of multidrug resistance (MDR), which l...

In the past two decades, the world has experienced an unprecedented number of extreme weather events, some causing major human suffering and economic damage. The March 2012 heat wave is one of the most known and broadly discussed events in the Northe...

In a recent paper, we extended a previous study on the solar solar influence to the generation of the March 2012 heatwave in the northeastern USA. In the present study we check the possible relationship of solar activity with the early March 2012 bad...

In this study, a novel space-time (ST) marching method is presented to solve linear and nonlinear transient flow problems in porous media. The method divides the ST domain into subdomains along the time axis. The solutions are approximated using ST p...

The Women’s March on 21 January 2017, opened a new social and political landscape for Muslim women to engage in Islamic liberatory activism. I locate Muslim women’s participation in the marches following the 2017 ‘Muslim travel ban...

Some new results and preliminary remarks about the Plio–Quaternary structural and evolutionary characteristics of the outer Marche Apennines south in the Conero promontory are presented in this study. The present analysis is based on several subsurfa...

Accurate environmental sensing is pivotal for advancing automation in construction, particularly in autonomous excavation. Precise 3D representations of complex and dynamic site geometries is essential for obstacle detection, progress monitoring, and...

Liver cancer is a very common and significant health problem. Therefore, powerful molecular targeting agents are urgently needed. Previously, we demonstrated that secalonic acid-F (SAF) suppresses the growth of hepatocellular carcinoma (HCC) cells (H...

The Zimbabwean crisis has been on-going since the year 2000. The various ecumenical bodies of the church in Zimbabwe have been voicing their concerns to the state through meetings and pastoral letters. While the church has been touted as a critical p...

The allergic march is a progression of naturally occurring symptoms whose nature changes with age. The classic allergic march typically begins in infancy and manifests in the form of atopic dermatitis and food allergy. As immune tolerance develops ov...

Simulating nonlinear classical dynamics on a quantum computer is an inherently challenging task due to the linear operator formulation of quantum mechanics. In this work, we provide a systematic approach to alleviate this difficulty by developing an...

The meridional distribution of the flow parameters inside the centrifugal compressor is of great importance to its overall performance, as well as its matching performance under a thermal cycle. A time-marching throughflow method for the off-design p...

The marching-on-in-degree (MOD) time-domain integral equation (TDIE) solver for the transient electromagnetic scattering of the graphene is presented in this paper. Graphene’s dispersive surface impedance is approximated using rational function expre...

The Marching On-In-Time (MOT) unstructured Partial Element Equivalent Circuit (PEEC) method for time domain electromagnetic problems is presented. The method allows the transient analysis of electrically large electromagnetic devices consisting of co...

Three strong earthquakes ruptured the northwest Thessaly area, Central Greece, on the 3, 4 and 12 March 2021. Since the area did not rupture by strong earthquakes in the instrumental period of seismicity, it is of great interest to understand the sei...

The study proposes two innovative algorithms in the field of multi-beam echo sounder (MBES) simulation: distance-aided sound ray marching (DASRM) and height-aided sound ray marching (HASRM). These algorithms aim to enhance the efficiency and accuracy...

(1) Background: The atopic march is defined by the increased prevalence of allergic diseases after atopic dermatitis onset. In fact, atopic dermatitis is believed to play an important role in allergen sensitization via the damaged skin barrier, leadi...

In this paper, we present a study on coverage missions carried out by UAV formations in 3D environments. These missions are designed to be applied in tracking and search and rescue missions, especially in the case of accidents. In this manner, the pr...

The distribution of archaeological sites in the rural landscape has attracted the attention of researchers over a long period of time, leading to the several site distribution approaches that have been proposed to explain existing patterns. The main...

When dealing with computed tomography volume data, the accurate segmentation of lung nodules is of great importance to lung cancer analysis and diagnosis, being a vital part of computer-aided diagnosis systems. However, due to the variety of lung nod...

We address the problem of accurately locating buried utility segments by fusing data from multiple sensors using a novel Marching-Cross-Section (MCS) algorithm. Five types of sensors are used in this work: Ground Penetrating Radar (GPR), Passive Magn...

Spring dust frequency in northeast Asia has been investigated using various approaches to understand the mechanisms of dust emission and transport. However, little attention has been paid to the linkage between dust activity and the Siberian High (SH...

In this paper, a combination of marching cubes and the constructive solid geometry method were merged to develop a simple, fast, and accurate method to estimate the shape of the soil in addition to the volume of the soil in the bucket during the digg...

The marching-on-in-degree (MOD) method is applied in this paper to analyze the transient electromagnetic scattering of multilayer graphene and a dielectric substrate. The time domain resistive boundary condition (TD-RBC) integral equation and time do...

The traditional Fast Marching Method (FMM) based on the finite-difference scheme can solve the traveltime of first arrivals; however, the accuracy and efficiency of FMM are usually affected by the finite-difference schemes and grid size. The Vidale f...

Mobile robot navigation has been studied for a long time, and it is nowadays widely used in multiple applications. However, it is traditionally focused on two-dimensional geometric characteristics of the environments. There are situations in which ro...

In the present study, a subject of atopic dermatitis (AD) is exposed progressively to allergic rhinitis (AR) and asthma (AS), which is defined as atopic march (AM). However, both the targets and compounds against AM are still largely unknown. Hence,...