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Nutrients, Volume 17, Issue 16

2025 August-2 - 142 articles

Cover Story: Our article “Beyond Infant Nutrition: Long-Term Neurodevelopmental Impact of Breastfeeding” reflects years of teamwork rooted in our hometown of Varna, Bulgaria. Together, we followed 92 children from birth to the age of five, performing neurodevelopmental testing and guiding families to early intervention when needed. By studying the effects of breastfeeding duration on neurodevelopment at five years old, we aimed not only to enrich global knowledge but also to strengthen local practices in early child development. Our findings highlight the potential of breastfeeding to support language and behavioral development, while reminding us that every child’s growth is shaped by complex social, nutritional, and environmental influences. This work embodies our dual mission: advancing science while giving back to the community that inspires us. View this paper
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Articles (142)

  • Article
  • Open Access
6 Citations
2,611 Views
19 Pages

Leveraging Deep Learning to Enhance Malnutrition Detection via Nutrition Risk Screening 2002: Insights from a National Cohort

  • Nadir Yalçın,
  • Merve Kaşıkcı,
  • Burcu Kelleci-Çakır,
  • Kutay Demirkan and ,
  • Karel Allegaert,
  • Meltem Halil,
  • Mutlu Doğanay and
  • Osman Abbasoğlu
  • + 3 authors+ 0 author

21 August 2025

Purpose: This study aimed to develop and validate a new machine learning (ML)-based screening tool for a two-step prediction of the need for and type of nutritional therapy (enteral, parenteral, or combined) using Nutrition Risk Screening 2002 (NRS-2...

(This article belongs to the Section Clinical Nutrition)
  • Article
  • Open Access
1 Citations
5,602 Views
16 Pages

21 August 2025

Background: The Dietary Guidelines for Americans (DGA) and the American Academy of Pediatrics recommend limiting 100% juice consumption to 0.5–1.25 cups/day and to no more than one half of total fruit intake. Objective: To explore the dietary b...

(This article belongs to the Section Nutritional Epidemiology)
  • Review
  • Open Access
5 Citations
4,255 Views
30 Pages

Natural Products as Modulators of Iron Metabolism and Ferroptosis in Diabetes and Its Complications

  • Yuanfen Xie,
  • Chunqin Li,
  • Xige Dong,
  • Beilei Wang and ,
  • Jiaxin Qin and
  • Huanhuan Lv
  • + 1 author+ 0 author

21 August 2025

Diabetes, a major global healthcare challenge, is characterized by chronic hyperglycemia and significantly exacerbates the severity of systemic complications. Iron, an essential element ubiquitously present in biological systems, is involved in many...

(This article belongs to the Section Nutrition and Diabetes)
  • Review
  • Open Access
11 Citations
6,588 Views
18 Pages

The Role of Nutrition and Physical Activity in Modulating Disease Progression and Quality of Life in Multiple Sclerosis

  • Cristina Grosu,
  • Emilian Bogdan Ignat,
  • Daniel Alexa,
  • Alin Ciubotaru and ,
  • Maria Magdalena Leon,
  • Alexandra Maștaleru,
  • Gabriela Popescu,
  • Carmen Marinela Cumpăt,
  • Laura-Elena Cucu and
  • Dan Trofin
  • + 6 authors+ 1 author

21 August 2025

Multiple sclerosis (MS) is a chronic, immune-mediated neurological disorder with increasing global prevalence. Emerging evidence underscores the role of lifestyle interventions (particularly diet and physical activity) in modulating disease progressi...

(This article belongs to the Special Issue Neurological Disorders: Diets and Nutrition)
  • Feature Paper
  • Article
  • Open Access
1 Citations
4,753 Views
17 Pages

21 August 2025

Background: Balancing nutrition security with environmental sustainability is a key priority in global food policy, with Sustainable Healthy Diets (SHDs) serving as a critical framework aligned with the UN Sustainable Development Goals (SDGs). Tradit...

(This article belongs to the Special Issue Mega-Trend: Sustainable Nutrition and Human Health)
  • Review
  • Open Access
4 Citations
3,479 Views
28 Pages

Helicobacter pylori and Compositional Patterns of Digestive Tract Microbiome in Children: A Literature Review

  • Ancuta Lupu,
  • Anca Adam-Raileanu,
  • Laura Iulia Bozomitu,
  • Nicoleta Gimiga and ,
  • Lorenza Forna,
  • Carmen Rodica Anton,
  • Maria Oana Sasaran,
  • Alin Horatiu Nedelcu,
  • Dragos Catalin Ghica and
  • Vasile Valeriu Lupu
  • + 9 authors+ 4 authors

21 August 2025

Helicobacter pylori (H. pylori) represents a major healthcare problem, colonizing more than half of the population worldwide. Usually acquired during childhood, it has a significant impact on human health. After forty years of extensive research, the...

(This article belongs to the Section Pediatric Nutrition)
  • Article
  • Open Access
1,849 Views
11 Pages

The Correlation Between Plasma Vitamin D and Blood Parameters in Prenatal Women

  • Yi Cheng Hou,
  • Jing Hui Wu,
  • Lu Lu Zhao,
  • Yin Guang Zhang and
  • Chyi Huey Bai

21 August 2025

Background/Objectives: Fat-soluble 25-hydroxyvitamin D (25-OHD) may be endogenously synthesized or obtained from dietary sources. Notably, it is crucial in calcium homeostasis, gene regulation, and immune system modulation, being even more relevant d...

(This article belongs to the Section Nutrition in Women)
  • Review
  • Open Access
6 Citations
5,114 Views
27 Pages

21 August 2025

Orphan nuclear receptor 4A1 (NR4A1) is a member of the NR4A subfamily that was initially discovered as an intermediate early gene expressed in response to stressors, including inflammatory agents. This review addresses the hypothesis that NR4A1 is a...

(This article belongs to the Section Geriatric Nutrition)
  • Review
  • Open Access
34 Citations
10,566 Views
51 Pages

Type 2 Diabetes and the Multifaceted Gut-X Axes

  • Hezixian Guo,
  • Liyi Pan,
  • Qiuyi Wu,
  • Linhao Wang and ,
  • Zongjian Huang,
  • Jie Wang,
  • Li Wang,
  • Xiang Fang,
  • Sashuang Dong and
  • Zhenlin Liao
  • + 6 authors+ 1 author

21 August 2025

Type 2 diabetes (T2D) is a complex metabolic disease characterized by chronic hyperglycemia due to insulin resistance and inadequate insulin secretion. Beyond the classically implicated organs, emerging evidence highlights the gut as a central player...

(This article belongs to the Special Issue Dietary Regulation of Glucose and Lipid Metabolism in Diabetes)
  • Article
  • Open Access
5 Citations
2,715 Views
16 Pages

Maternal Adherence to Healthy Dietary Patterns During Pregnancy and Gestational Weight Gain

  • Shan-Xuan Lim,
  • Siona Wadhawan,
  • Elizabeth A. DeVilbiss,
  • Priscilla K. Clayton and ,
  • Kathryn A. Wagner,
  • Jessica L. Gleason,
  • Zhen Chen,
  • Cuilin Zhang,
  • Katherine L. Grantz and
  • Jagteshwar Grewal
  • + 5 authors+ 0 author

21 August 2025

Background/Objectives: Suboptimal gestational weight gain (GWG) has been linked to increased risks of adverse maternal outcomes. Evidence linking diet in pregnancy to GWG remains limited. We assessed relationships between adherence to five dietary pa...

(This article belongs to the Special Issue Maternal Diet, Body Composition and Offspring Health)
  • Review
  • Open Access
3 Citations
6,663 Views
21 Pages

Ergogenic and Physiological Effects of Sports Supplements: Implications for Advertising and Consumer Information

  • Pedro Estevan Navarro,
  • Cristina González-Díaz,
  • Rubén García Pérez,
  • Angel Gil-Izquierdo and ,
  • Carlos Javier García,
  • Daniel Giménez-Monzo,
  • Alejandro Perales and
  • José Miguel Martínez Sanz
  • + 3 authors+ 0 author

21 August 2025

Background: The use of sports supplements has increased significantly in athletic contexts, raising the need to evaluate their efficacy, safety, regulatory status, and communication practices. Objective: This study aimed to describe and synthesize th...

(This article belongs to the Special Issue Effects of Exercise and Diet on Health)
  • Article
  • Open Access
2,110 Views
13 Pages

21 August 2025

Background: The association between milk-derived or dairy product intake (DPI) and the body composition (BC) of children and adolescents continues to be controversial. Objective: This study sought to evaluate the association between the quantity and...

(This article belongs to the Section Pediatric Nutrition)
  • Article
  • Open Access
1,557 Views
14 Pages

Adaptation of the Child Coeliac Disease Food Attitudes and Behaviours Scale (Child CD-FAB) into Brazilian Portuguese: Translation and Evaluation of Reproducibility and Internal Consistency

  • Marina de Cesaro Schwantes,
  • Heather Maddison-Roberts,
  • Eduardo Yoshio Nakano,
  • Raquel Braz Assunção Botelho and
  • Renata Puppin Zandonadi

21 August 2025

Background/Objectives: This study aimed to translate the Child Coeliac Disease Food Attitudes and Behaviours Scale (Child CD-FAB) into Brazilian Portuguese and to evaluate its reproducibility and internal consistency. Methods: Three steps were carrie...

(This article belongs to the Special Issue Gluten-Free Diet and Supportive Nutrition Care Plans)
  • Review
  • Open Access
14 Citations
3,827 Views
19 Pages

Nutritional Status Assessment Tools in Cardiovascular Patients

  • Izabela Jarosz,
  • Kamil Gorecki,
  • Grzegorz Kalisz and
  • Joanna Popiolek-Kalisz

20 August 2025

Background: Malnutrition is a prevalent but underrecognized condition in cardiovascular disease (CVD) patients, associated with adverse outcomes including longer hospitalizations, higher readmission rates, and increased mortality. Traditional measure...

(This article belongs to the Special Issue Nutritional Aspects of Cardiovascular Disease Risk Factors)
  • Article
  • Open Access
5 Citations
4,196 Views
13 Pages

Breastfeeding and Sociodemographic Determinants: Evidence from the “MAMI-MED” Cohort

  • Giuliana Favara,
  • Andrea Maugeri,
  • Martina Barchitta,
  • Roberta Magnano San Lio and ,
  • Maria Clara La Rosa,
  • Claudia La Mastra,
  • Erminia Di Liberto,
  • Fabiola Galvani,
  • Elisa Pappalardo and
  • Antonella Agodi
  • + 7 authors+ 2 authors

20 August 2025

Background/Objectives: Breastfeeding is key to maternal and child health, but adherence to WHO recommendations varies worldwide and is influenced by several maternal and paternal factors. In this study, we aim to describe the prevalence of breastfeed...

(This article belongs to the Special Issue Maternal Nutrition: Developmental Origins of Health and Disease)
  • Article
  • Open Access
2 Citations
3,469 Views
28 Pages

Investigation into Efficacy and Mechanisms of Neuroprotection of Ashwagandha Root Extract and Water-Soluble Coenzyme Q10 in a Transgenic Mouse Model of Alzheimer’s Disease

  • Caleb Vegh,
  • Gabrielle Walach,
  • Keanna Dube,
  • Bromleigh Dobson and ,
  • Rohan Talukdar,
  • Darcy Wear,
  • Hasana Jayawardena,
  • Kaitlyn Dufault,
  • Lauren Culmone and
  • Siyaram Pandey
  • + 9 authors+ 4 authors

20 August 2025

Background: Alzheimer’s Disease (AD) is one of the most prevalent neurodegenerative disorders and the most common form of dementia. Although current treatments examine disease progression, many have side effects and primarily target symptomatic...

(This article belongs to the Section Nutritional Immunology)
  • Review
  • Open Access
9 Citations
16,435 Views
54 Pages

Beyond GLP-1 Agonists: An Adaptive Ketogenic–Mediterranean Protocol to Counter Metabolic Adaptation in Obesity Management

  • Cayetano García-Gorrita,
  • Nadia San Onofre,
  • Juan F. Merino-Torres and
  • Jose M. Soriano

20 August 2025

Background/Objectives: Long-term obesity management consistently fails due to two major barriers: poor adherence, exacerbated by ultra-processed foods with addictive potential, and post-weight loss metabolic adaptation that reduces energy expenditure...

(This article belongs to the Special Issue The Ketogenic Diet: Biochemical Mechanisms and Clinical Applications)
  • Article
  • Open Access
2 Citations
2,061 Views
15 Pages

20 August 2025

Background/Objectives: Fetal exposure to essential metals, such as iron (Fe), zinc (Zn), copper (Cu), and manganese (Mn), is influenced by maternal nutrition and lifestyle during pregnancy, potentially impacting newborn health. This study aimed to qu...

(This article belongs to the Special Issue Diet, Maternal Nutrition and Reproductive Health)
  • Article
  • Open Access
6 Citations
2,505 Views
13 Pages

20 August 2025

Purpose: Chronic low-grade inflammation is increasingly recognized as a contributor to age-related muscle loss and functional decline, yet its association with muscle strength in Asian populations remains underexplored. Therefore, this study aimed to...

(This article belongs to the Section Geriatric Nutrition)
  • Review
  • Open Access
31 Citations
8,500 Views
22 Pages

20 August 2025

Obesity is a global health challenge marked by substantial inter-individual differences in responses to dietary and lifestyle interventions. Traditional weight loss strategies often overlook critical biological variations in genetics, metabolic profi...

(This article belongs to the Section Nutrition and Public Health)
  • Review
  • Open Access
11 Citations
3,623 Views
23 Pages

Sex Differences in Vitamin Metabolism and Their Role in Oxidative Stress Regulation and Cardiometabolic Health

  • Joanna Wróblewska,
  • Anna Długosz,
  • Marcin Wróblewski,
  • Jarosław Nuszkiewicz and ,
  • Weronika Wróblewska and
  • Alina Woźniak
  • + 1 author+ 0 author

20 August 2025

Vitamins A, D, E, K, B2, B12, and C play a key role in regulating metabolism and oxidative stress, significantly impacting cardiometabolic health. This review uniquely integrates mechanistic and epidemiological data to examine sex-specific difference...

(This article belongs to the Section Clinical Nutrition)
  • Article
  • Open Access
3 Citations
2,269 Views
17 Pages

Dietary Iron Intake Impacts the Microbial Composition of the Murine Intestinal and Lung Microbiome

  • Ama-Tawiah Essilfie,
  • Alison Smith,
  • Rebecca Watts,
  • Pramila Maniam and ,
  • Iain L. Lamont,
  • David M. Frazer,
  • Gregory J. Anderson and
  • David W. Reid
  • + 3 authors+ 0 author

20 August 2025

Background: Iron is an essential nutrient for many bacterial pathogens and normal cellular function and homeostasis of their hosts. Studies suggest that iron deficiency or overload may contribute to the pathogenesis of several chronic conditions and...

(This article belongs to the Special Issue Mineral Nutrition on Human Health and Disease)
  • Article
  • Open Access
3 Citations
10,188 Views
18 Pages

Adding L-Carnitine and Selenium to Methimazole in Graves’ Disease: A Prospective Randomized Trial on Thyroid Markers and Quality of Life

  • Mattia Rossi,
  • Letizia Meomartino,
  • Marco Zavattaro,
  • Gloria Selvatico and ,
  • Ruth Rossetto Giaccherino and
  • Loredana Pagano
  • + 1 author+ 0 author

20 August 2025

Background: The therapeutic response in Graves’ Disease (GD) remains largely unpredictable. Patients often experience persistent symptoms that are poorly correlated with thyroid hormone levels, an undefined treatment duration, and the need for...

(This article belongs to the Section Nutrition and Metabolism)
  • Article
  • Open Access
5 Citations
3,298 Views
13 Pages

Hidden Malnutrition in Overweight and Obese Individuals with Chronic Heart Failure: Insights from the Pro-HEART Trial

  • Angelina P. Nguyen,
  • Jennifer Kawi,
  • Rebecca Meraz,
  • Kelly L. Wierenga and ,
  • Alona D. Angosta,
  • Michele A. Hamilton,
  • Gregg C. Fonarow and
  • Lorraine S. Evangelista
  • + 3 authors+ 0 author

20 August 2025

Background/Objectives: Poor nutritional status and cachexia have been well-documented as predictors of adverse outcomes in individuals with chronic heart failure (HF). However, despite obesity being a common observation in this patient population, a...

(This article belongs to the Section Nutrition and Obesity)
  • Article
  • Open Access
6 Citations
2,984 Views
19 Pages

Planetary Health Diet and Body Mass Distribution in Relation to Kidney Health: Evidence from NHANES 2003–2018

  • Guido Gembillo,
  • Luca Soraci,
  • Maria Elsa Gambuzza,
  • Maria Princiotto and ,
  • Antonino Catalano,
  • Edlin Villalta,
  • Salvatore Silipigni,
  • Giada Ida Greco,
  • Andrea Corsonello and
  • Domenico Santoro
  • + 5 authors+ 0 author

20 August 2025

Background/Objectives: Chronic kidney disease (CKD) and diabetic kidney disease (DKD) are growing public health challenges. While diet and body composition influence metabolic and renal health, their combined role remains underexplored. This study in...

(This article belongs to the Section Nutrition Methodology & Assessment)
  • Systematic Review
  • Open Access
11 Citations
4,959 Views
32 Pages

The Effect of Nutrition Impact Symptoms on Nutrition Status After Completion of Curative-Intent Treatment for Gastric, Oesophageal, and Pancreatic Cancer: A Systematic Review

  • Emma McShane,
  • Lauren Hanna,
  • Carmel Zoanetti,
  • Lisa Murnane and ,
  • Brenton Baguley and
  • Kate Furness
  • + 1 author+ 0 author

20 August 2025

Background/Objectives: Gastric, oesophageal, and pancreatic cancers are common worldwide, with low but improving survival rates due to advances in curative treatments. However, these treatments often cause long-term nutrition impact symptoms that are...

(This article belongs to the Special Issue Diet and Nutrition Approaches to Support Cancer Patients Post-Acute Active Treatment)
  • Article
  • Open Access
8 Citations
2,429 Views
12 Pages

The Relationship Between Nutritional Status, Micronutrient Deficiency, and Disease Activity in IBD Patients: A Multicenter Cross-Sectional Study

  • Marco Valvano,
  • Susanna Faenza,
  • Fabio Cortellini,
  • Antonio Vinci and ,
  • Fabio Ingravalle,
  • Mauro Calabrò,
  • Lorenza Scurti,
  • Mariagiulia Di Nezza,
  • Sergio Valerio and
  • Giovanni Latella
  • + 6 authors+ 1 author

20 August 2025

Background and aim: Inflammatory bowel diseases (IBD) are chronic conditions that affect the gastrointestinal tract. The chronic inflammatory state promotes a catabolic environment that contributes to undernutrition, while mucosal damage often impair...

(This article belongs to the Section Clinical Nutrition)
  • Article
  • Open Access
4 Citations
6,343 Views
11 Pages

20 August 2025

Background: In Poland, the consumption of energy drinks among young people has changed significantly following the introduction of a ban on sales to minors. This regulatory measure was intended to address growing concerns about the health effects of...

(This article belongs to the Section Nutritional Epidemiology)
  • Article
  • Open Access
8 Citations
6,176 Views
15 Pages

Moderate Alcohol Consumption and Risk of Depression: A Longitudinal Analysis in Community-Dwelling Older Adults

  • Mohammadreza Mohebbi,
  • Najmeh Davoodian,
  • Shiva Ganjali,
  • Lawrence J. Beilin and ,
  • Michael Berk,
  • Malcolm Forbes,
  • John J. McNeil,
  • Mark R Nelson,
  • Joanne Ryan and
  • Mojtaba Lotfaliany
  • + 7 authors+ 2 authors

20 August 2025

Background/Objectives: Evidence suggests a J-shaped association between alcohol consumption and depression, but it remains unclear whether this reflects a true causal effect, reverse causation, or methodological bias. This uncertainty is particularly...

(This article belongs to the Section Nutrition and Public Health)
  • Review
  • Open Access
7 Citations
9,155 Views
27 Pages

Associations of the MIND Diet with Human Health Outcomes: A Scoping Review

  • Katherine Hope Morgan,
  • Michelle Lanphere Lee,
  • Cristina S. Barroso,
  • Joel G. Anderson and ,
  • Shelley Lott,
  • Danielle Reth,
  • Chelsea Horn and
  • Melanie Dixson
  • + 3 authors+ 0 author

20 August 2025

The MIND diet was designed as an intervention to delay neurodegeneration and has been explored by systematic reviews for associations with cognition and, more recently, cardiometabolic disease. Comparatively less is known about how the MIND diet is a...

(This article belongs to the Special Issue Therapeutic Potential of Phytochemicals in Neurodegenerative Diseases)
  • Article
  • Open Access
3 Citations
2,790 Views
23 Pages

Exploring Body Composition and Eating Habits Among Nurses in Poland

  • Anna Bartosiewicz,
  • Katarzyna Dereń,
  • Edyta Łuszczki,
  • Magdalena Zielińska and ,
  • Justyna Nowak,
  • Anna Lewandowska and
  • Piotr Sulikowski
  • + 2 authors+ 0 author

20 August 2025

Background/Objectives: Nurses play a vital role in healthcare, yet their demanding working conditions, including long hours, shift work, and stress, can negatively impact health behaviors. In Poland, empirical data on nurses’ eating habits and...

(This article belongs to the Section Nutrition and Metabolism)
  • Systematic Review
  • Open Access
2 Citations
9,651 Views
18 Pages

Comparison with Dietary Groups of Various Macronutrient Ratios on Body Weight and Cardiovascular Risk Factors in Adults: A Systematic Review and Network Meta-Analysis

  • Yiling Lou,
  • Hengchang Wang,
  • Linlin Wang,
  • Shen Huang and ,
  • Yulin Xie,
  • Fujian Song,
  • Zuxun Lu,
  • Furong Wang,
  • Qingqing Jiang and
  • Shiyi Cao
  • + 5 authors+ 0 author

19 August 2025

Background: This network meta-analysis aimed to assess the relative efficacy of macronutrient dietary groups with varying carbohydrate, fat, and protein ratios on weight control and cardiovascular risk factors improvement in adults. Methods: We searc...

(This article belongs to the Section Nutrition and Public Health)
  • Article
  • Open Access
4 Citations
2,490 Views
24 Pages

19 August 2025

Background: Rational dietary patterns and adequate nutritional status support athlete health and performance, while unhealthy habits may impair these outcomes. This study aimed to identify dietary patterns among Polish professional athletes using a f...

(This article belongs to the Section Sports Nutrition)
  • Article
  • Open Access
1 Citations
2,484 Views
17 Pages

Chemical Profiling and UPLC-qTOF-MS/MS-Based Metabolomics of Three Different Parts of Edgeworthia chrysantha and Identification of Glucose Uptake-Enhancing Compounds

  • Jin-Pyo An,
  • Sohee Han,
  • Van-Hieu Mai,
  • Jorge-Eduardo Ponce-Zea and ,
  • Gi Hyeon Seong,
  • Thi-Kim-Quy Ha and
  • Won Keun Oh
  • + 2 authors+ 0 author

19 August 2025

Background/Objectives: Edgeworthia chrysantha is rich in coumarin and flavonoid dimers, which may exhibit diverse pharmacological activities. However, to date, no metabolomics studies have been conducted and its bioactive constituents related to gluc...

(This article belongs to the Section Phytochemicals and Human Health)
  • Opinion
  • Open Access
2 Citations
1,786 Views
10 Pages

19 August 2025

The present article is an opinion piece mainly based on selected articles in the field of sarcopenia, with possible relevance for pregnancy. Sarcopenia has gained increasing interest in recent years, since it has emerged that sarcopenia may determine...

(This article belongs to the Special Issue Maternal Gestational Diabetes and Its Impact on Fetal Health)
  • Article
  • Open Access
2 Citations
3,569 Views
14 Pages

19 August 2025

Background/Objectives: Unhealthy snacking, most commonly consisting of sweets, savoury snacks and sugar-sweetened beverages, is associated with various adverse health outcomes. As long-term eating behaviours are commonly established in young adulthoo...

(This article belongs to the Special Issue Body Image and Nutritional Status from Childhood to Adulthood)
  • Article
  • Open Access
3 Citations
3,311 Views
16 Pages

Effects of Oral Anthocyanin Supplementation on In Vitro Neurogenesis, Hippocampus-Dependent Cognition, and Blood-Based Dementia Biomarkers: Results from a 24-Week Randomized Controlled Trial in Older Adults At Risk for Dementia (ACID)

  • Chiara de Lucia,
  • Diego Alejandro Tovar-Rios,
  • Khadija Khalifa,
  • Silje Meihack Kvernberg and ,
  • Ilaria Pola,
  • Anne Katrine Bergland,
  • Jodi Maple-Grødem,
  • Richard Siow,
  • Nicholas Ashton and
  • Dag Aarsland
  • + 7 authors+ 2 authors

19 August 2025

Background: Identifying compounds with neuroprotective properties that target the neurogenic process will have a considerable impact on dementia prevention. Methods: This is a secondary analysis of a 24-week randomised, double-blind, placebo-controll...

(This article belongs to the Special Issue Dietary Supplement in Neurodegenerative Diseases: Nutritional Assessment)
  • Article
  • Open Access
4 Citations
2,044 Views
22 Pages

19 August 2025

Background: Obesity is clinically known to be associated with an increased risk and aggravated pathology of Alzheimer’s disease (AD). A high-fat diet (HFD), the major contributor to obesity, induces neuroinflammation and central insulin resista...

(This article belongs to the Section Nutrition and Neuro Sciences)
  • Article
  • Open Access
1 Citations
1,720 Views
28 Pages

Methylomic Signature and Epigenetic Damage Modulation of Bronte Pistachio (Pistacia vera L.) Hydrophilic Extract in Differentiated CaCo-2 Cells

  • Ilenia Cruciata,
  • Flores Naselli,
  • Sara Volpes,
  • Paola Sofia Cardinale and ,
  • Laura Greco,
  • Federico Martinelli,
  • Matteo Ramazzotti,
  • Anna Perrone,
  • Graziella Serio and
  • Fabio Caradonna
  • + 6 authors+ 1 author

19 August 2025

Background/Objectives: Nutrigenomics explores how dietary components influence genome function, especially via epigenetic mechanisms like DNA methylation. A key challenge is identifying healthy food-derived molecules capable of counteracting epigenet...

(This article belongs to the Section Nutrigenetics and Nutrigenomics)
  • Review
  • Open Access
34 Citations
18,005 Views
21 Pages

Ultra-Processed Foods, Gut Microbiota, and Inflammatory Bowel Disease: A Critical Review of Emerging Evidence

  • Amanda Luísa Spiller,
  • Beatriz Gabriela da Costa,
  • Ryan Nunes Yoshio Yoshihara,
  • Enya Julia Zucari Nogueira and ,
  • Natalia Salvador Castelhano,
  • Andrey Santos,
  • Maiara Brusco De Freitas,
  • Daniéla Oliveira Magro and
  • Ligia Yukie Sassaki
  • + 4 authors+ 0 author

19 August 2025

Background/Aims: Inflammatory bowel diseases (IBDs), including Crohn’s disease (CD) and ulcerative colitis (UC), are chronic conditions marked by dysregulated inflammation in the gastrointestinal tract. Although the pathophysiology of IBD remai...

(This article belongs to the Special Issue Diet, Gut Health, and Clinical Nutrition)
  • Review
  • Open Access
3 Citations
5,205 Views
12 Pages

Drugs and Nutrients in Epilepsy: Vitamin B6 and the Ketogenic Diet

  • Shani Bahalul-Yarchi,
  • Feigy Hartman,
  • Karin Ben Zaken,
  • Ibrahim O. Sawaid and ,
  • Lior Segev,
  • Samuel Mesfin,
  • Pnina Frankel,
  • Rahaf Ezzy and
  • Abraham O. Samson
  • + 4 authors+ 0 author

19 August 2025

Certain foods and specific drugs have been linked to epilepsy in the literature. Here, we query PubMed citations for the co-occurrence of epilepsy with foods and drugs, using a list of 217,776 molecules from the HMDB. Notably, the top associations wi...

(This article belongs to the Section Nutrition and Neuro Sciences)
  • Article
  • Open Access
6 Citations
5,751 Views
19 Pages

Association of Healthy Predominantly Plant-Based Diet with Reduced Cardiovascular Disease Incidence and Mortality and Development of Novel Heart-Protective Diet Index

  • Tian Wang,
  • Andrea Nova,
  • Sophie Cassidy,
  • Katherine M. Livingstone and ,
  • Teresa Fazia,
  • Sayan Mitra,
  • Cynthia M. Kroeger,
  • Andrius Masedunskas,
  • Luisa Bernardinelli and
  • Luigi Fontana
  • + 6 authors+ 1 author

19 August 2025

Background: Previous research examining the effects of omnivorous and plant-based diets on cardiovascular disease (CVD) outcomes has produced inconsistent findings, and the importance of diet quality is overlooked. Our study aimed to develop a novel...

(This article belongs to the Section Nutrition and Public Health)
  • Article
  • Open Access
4 Citations
6,914 Views
18 Pages

19 August 2025

Background: Grain foods are important sources of complex carbohydrates, fiber, vitamins, and minerals. Objective: To identify healthy grain foods and to assess their associations with composite diet quality measures and selected health outcomes. Meth...

(This article belongs to the Section Carbohydrates)
  • Review
  • Open Access
17 Citations
10,477 Views
17 Pages

Genetic Variants Influencing Individual Vitamin D Status

  • Niel A. Karrow,
  • Spencer E. Leuschner,
  • Umesh K. Shandilya,
  • Bonnie A. Mallard and ,
  • Lauraine Wagter-Lesperance and
  • Byram W. Bridle
  • + 1 author+ 0 author

19 August 2025

Vitamin D (VD) plays a critical role in human health, with deficiencies linked to a range of adverse outcomes, including compromised immune function and increased disease risk. While environmental factors such as sunlight exposure and diet influence...

(This article belongs to the Special Issue Effects of Vitamin D Deficiency on Human Health, Nutritional Status, and Disease Prevention with Micronutrients)
  • Article
  • Open Access
8 Citations
2,729 Views
17 Pages

Fatty Acid Profiling of Breast Milk at Different Gestational Ages

  • Giuseppe De Bernardo,
  • Giuseppina Leone,
  • Federica Izzo,
  • Marta Giovengo and ,
  • Manuela Giovanna Basilicata,
  • Fabio Centanni,
  • Francesca Morlino,
  • Emanuela Salviati,
  • Maurizio Giordano and
  • Pietro Campiglia
  • + 9 authors+ 4 authors

19 August 2025

Background/objectives: This study aimed to characterize the fatty acid (FA) profile of breast milk (BM) at 7 days (T7) and 1 month postpartum (T30) using gas chromatography–mass spectrometry (GC-MS) and to evaluate associations between maternal...

(This article belongs to the Special Issue Nutritional Requirements of Pregnant and Lactating Women)
  • Article
  • Open Access
5 Citations
3,868 Views
19 Pages

Protein Substitute Absorption: A Randomised Controlled Trial Comparing CGMP vs. Amino Acids vs. Micellar Casein in Healthy Volunteers

  • Anne Daly,
  • Alex Pinto,
  • Sharon Evans,
  • Tarekegn Geberhiwot and ,
  • Richard Jackson,
  • Júlio César Rocha,
  • Jonathan C. Y. Tang and
  • Anita MacDonald
  • + 3 authors+ 0 author

19 August 2025

Background: The rate at which amino acids (AAs) are absorbed from casein glycomacropeptide (CGMP) when given as a protein substitute in phenylketonuria (PKU) is unknown. This three-way randomised, controlled, crossover study aimed to compare the AA a...

(This article belongs to the Section Nutrition and Metabolism)
  • Article
  • Open Access
1 Citations
9,951 Views
11 Pages

Intravenous Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia During Pregnancy: Effects on Maternal and Fetal Wellbeing—A Multicenter Retrospective Observational Study

  • Eleonora Romani,
  • Sara Zullino,
  • Anna R. Speciale,
  • Paola M. Villa and ,
  • Veronica Bonaldo,
  • Francesca Parisi,
  • Chiara Lubrano,
  • Felice Petraglia,
  • Irene Cetin and
  • Federico Mecacci
  • + 5 authors+ 0 author

19 August 2025

Objectives: To assess the impact of intravenous ferric carboxymaltose (FCM) on fetal and maternal adverse effects in pregnant women diagnosed with iron deficiency anemia (IDA). Methods: This is a multicenter retrospective study on 472 pregnant women...

(This article belongs to the Special Issue Maternal Diet, Body Composition and Offspring Health)
  • Article
  • Open Access
3,199 Views
17 Pages

Interplays of ADH1B Genotype, Alcohol Consumption, and Gut Microbiota in Relation to Insulin Resistance

  • Brian Wang,
  • Brandilyn A. Peters-Samuelson,
  • Kai Luo,
  • Christina Cordero and ,
  • Krista M. Perreira,
  • Amber Pirzada,
  • Martha L. Daviglus,
  • Yang Li,
  • Robert C. Kaplan and
  • Qibin Qi
  • + 6 authors+ 1 author

18 August 2025

Background/Objective: Alcohol consumption has been linked to alterations in gut microbiota and insulin resistance. The alcohol dehydrogenase 1B (ADH1B) gene plays a crucial role in alcohol catabolism, where rs1229984 variant carriers (CT/TT) cataboli...

(This article belongs to the Section Nutrition and Diabetes)
  • Review
  • Open Access
21 Citations
11,633 Views
11 Pages

18 August 2025

Robust statistical analysis is essential for advancing evidence-based nutrition research, particularly when investigating the complex relationships between dietary exposure and health outcomes. Multiple regression is a widely used analytical techniqu...

(This article belongs to the Section Nutrition and Public Health)
  • Article
  • Open Access
4 Citations
7,405 Views
14 Pages

Synergistic Effects of MTHFR, MTRR, and MTR Gene Variants on Serum Folate Levels and Cognitive Function in Chinese Preschoolers: A Cross-Sectional Study

  • Lingling Ou,
  • Luolan Peng,
  • Jingbo Wang,
  • Chao Han and ,
  • Xiayu Zhao,
  • Mengyao Wang,
  • Mengtian Wang,
  • Zhaolong Gong and
  • Yan Li
  • + 4 authors+ 0 author

18 August 2025

Background/Objectives: Subnormal folate levels have a detrimental impact on the growth and development of preschoolers. We aimed to investigate the association between independent/synergistic effects of the gene polymorphisms (methyltetrahydrofolate...

(This article belongs to the Section Pediatric Nutrition)

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Nutrients - ISSN 2072-6643