Background: Folate is essential for one-carbon metabolism, yet deficiency remains common in non-fortified populations. Bitter-taste-receptor genetics may influence vegetable intake and thus folate status, but the cumulative impact of sensory genetics...
Background/Objectives: Nutrition labeling and food advertising are population-level strategies that may influence food choices. Excess weight is a recognized public health concern and a risk factor for cardiometabolic diseases; however, evidence rega...
Background: Autoimmune diseases (ADs) are a growing global health burden, driven by chronic inflammation and immune dysregulation. The gut-immune axis plays a central role in their pathogenesis, with dysbiosis linked to several conditions. This has p...
Background: Autoimmune diseases (AIDs) are characterized by chronic inflammation and tissue damage resulting from abnormal immune responses. While genetic and environmental factors play significant roles in disease development, essential micronutrien...
Background/Objectives: This study examined the relationship between adherence to the Mediterranean diet (MD), dietary and vitamin intake, physical activity, and body composition in young adults. Methods: A total of 145 Spanish university students (34...
Background/Objectives: Zinc is an essential trace element involved in multiple aspects of immune function, including epithelial barrier integrity, innate and adaptive immune responses, regulation of inflammation and oxidative stress. Zinc deficiency...
Objective: To systematically evaluate the potential of Saussurea involucrata cultures (SICs) against high-altitude illness under hypobaric hypoxia and establish a progressive experimental evidence chain covering acute hypoxia tolerance enhancement an...
Background: Cognitive disorders are a class of neurological diseases characterized by declines in cognitive function, imposing a heavy physical and mental burden on middle-aged and elderly individuals. Since the underlying mechanisms of cognitive dis...
Background/Objectives: This study evaluated the immunomodulatory effects of multiple A. bisporus strains, applying both in vitro and in vivo murine models and aiming to identify specific strains with immune modulatory properties. Methods: Sixteen A. ...
Background/Objectives: Legume-enriched foods are conventional products reformulated with the addition of legumes and, as such, represent a sustainable alternative to animal proteins. This study investigated the effectiveness of messages based on diff...
Background. The Mediterranean dietary pattern (MDP) is recognised as one of the most evidence-based dietary models for the prevention of non-communicable diseases (NCDs). Its plant-rich composition suggests an inherently high potassium intake, yet ep...
Weight management after metabolic and bariatric surgery remains a persistent clinical challenge, particularly when patients experience insufficient weight loss or progressive weight regain following the postoperative nadir. In recent years, pharmacol...
Background/Objectives: Skin carotenoid measurements have been proposed as an indicator to reflect of fruit and vegetable intake, but evidence from occupational settings remains limited. The primary aim of this study was to assess the association betw...
Background and Objective: Male individuals diagnosed with metabolic dysfunction-associated steatotic liver disease (MASLD) frequently present with decreased blood testosterone concentrations concomitant with increased levels of hepatic cholesterol, t...
Background/Objectives: Although curcumin (CUR) and resveratrol (RSV) are natural polyphenolic compounds with reported anticancer and anti-inflammatory properties, their combined anticancer effects in melanoma cells remain incompletely characterized....
Metabolic diseases such as type 2 diabetes and obesity are increasingly recognized as disorders of dysregulated cellular communication rather than solely enzymatic or transcriptional dysfunction. While conventional therapies primarily target metaboli...
Background: Self-esteem plays a central role in adolescent psychological health and may be shaped by everyday health behaviors such as eating patterns and engagement in physical activity. However, evidence from Eastern European youth remains comparat...
Background: Eco-anxiety is increasingly viewed as a multidimensional response to the climate crisis, but its links with religiosity and sustainable nutrition behaviors in highly religious settings are unclear. We identified eco-anxiety profiles in Tu...
Objective: This systematic review aimed to evaluate the efficacy and safety of preoperative nutrition-based interventions on pre-, intra-, and postoperative outcomes in children undergoing cardiac surgical procedures. Methods: CENTRAL, MEDLINE, and E...
Introduction: Sarcopenia and frailty are prevalent yet under-recognized contributors to disability, impaired quality of life, and adverse outcomes in chronic obstructive pulmonary disease (COPD). Shared mechanisms, including systemic inflammation, ho...
Background/Objectives: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is a prevalent condition defined by hepatic fat accumulation, inflammation, and metabolic dysregulation. Current evidence demonstrates that gut microbiota and the...
Objectives: The objective of this study was to evaluate the effect of 21-day dietary omega-3 fatty acid supplementation on the levels of postexercise inflammation response, oxidative stress, and selected exerkine secretion among physically active you...
Background/Objectives: Hypozincemia associated with severe trauma contributes to immune dysfunction and poor prognosis; however, the clinical utility and optimal dosage of zinc supplementation remain unclear. In particular, it is unclear whether high...
Background/Objectives: School meals play an important role in ensuring reliable, healthy access to food, but there are many barriers to participation, especially for rural students. This study examined the perceived impact of UFSM policies and the pe...
Background/Objectives: Larix decidua has been used in traditional medicine for the treatment of various inflammatory conditions. Although their use has been recognized in alternative medicine, the scientific documentation of the antioxidant and anti-...
Background/Objectives: Xanthones from the tropical fruit mangosteen (Garcinia mangostana) have been reported to modulate oxidative stress and inflammatory responses. This work explored the anti-inflammatory potential of mangosteen in the form of tinc...
Objective: To assess the relationship between adherence to various plant-based diets, as measured by overall, healthy, and unhealthy plant-based diet indices (PDI, hPDI, uPDI), and ovarian cancer risk. Methods: We obtained data on 1031 cases of ovari...
Background/Objectives: Contemporary food systems face dual imperatives of ensuring nutritional adequacy while minimizing environmental resource consumption, yet conventional dietary assessment methodologies inadequately integrate these competing obje...
Background/Objectives: Sustainable diets are essential for public health, food system resilience, and environmental protection, yet engagement with healthy sustainable dietary actions is varied. This study investigated knowledge, perceived importance...
Background: Eating habits influence cardiometabolic health alongside traditional dietary measures. However, the links between dietary patterns, body composition, and heart-healthy food preferences remain under-explored in large cohorts. Methods: In t...
Background/Objectives: The global prevalence of overweight and obesity among young adults has doubled since 1975, primarily due to unhealthy dietary habits and sedentary lifestyles. Understanding dietary patterns (DPs) in this population is essential...
Background: Sepsis-induced organ dysfunction poses a significant clinical challenge with limited therapeutic options. This study investigated the therapeutic potential of the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide in sepsis an...
Background: Post-traumatic stress disorder (PTSD) and trauma-related disorders are increasingly recognized as complex conditions involving not only psychological and neurobiological factors but also systemic physiological alterations. Among these, gr...
The overall health impact of alcohol remains controversial. The Global Burden of Disease (GBD) study made headlines in 2018 by stating that zero alcohol was the safest option. However, its 2022 update introduced age-specific adaptations, asserting th...
Population ageing is no longer a future scenario but a present reality, reshaping not only the epidemiology of chronic disease but also the fundamental goals of medicine and public health [...]
With the continuous improvement in living standards, consumers are shifting their focus from merely achieving satiety and food safety to prioritizing nutrition and health, placing greater emphasis on the nutritional value of food and healthy dietary...
Background/Objectives: Mitochondrial dysfunction, often reflected by a decline in mitochondrial DNA copy number (mtDNA-CN) in peripheral blood cells (PMBCs), is a key hallmark of biological aging and is linked to numerous adverse health outcomes, inc...
Background/Objectives: Mango is a tropical fruit rich in polyphenols and carotenoids that may support recovery-related physiological responses during athletic training. This study examined the effects of mango puree supplementation on inflammatory bi...
Background/Objectives: Upper respiratory tract infections (URTIs) and exercise-induced immune perturbations are common in adults and may adversely affect quality of life, productivity, and physical performance. Immunoglobulin Y (IgY), a food-derived...
Background: Oedema is a multifactorial condition arising from the interplay between increased microvascular permeability, impaired lymphatic clearance, and sustained inflammation. Conventional treatments often fail, highlighting alternative therapies...
Background/Objectives: After fermentation, yogurt is often supplemented with probiotics, yet sweetened with added sugars that can negatively impact cardiometabolic health. Honey provides rare sugars, oligosaccharides and phenolics that may promote gu...
Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) can develop as post-vaccination syndrome (PVS) or Post-Acute Sequelae of SARS-CoV-2 infection (PASC). In our prior retrospective study, most patients with PVS who developed ME/CF...
Background: Xanthohumol (XN), a prenylated chalcone flavonoid derived from hops (Humulus lupulus), is increasingly recognized as a highly pleiotropic natural compound. Objective: We aimed to structure XN’s mechanistic hierarchy with emerging tr...
Background/Objectives: Energy availability (EA) is associated with Relative Energy Deficiency in Sport syndrome. This study assessed the EA, body composition, and phase angle (φ) of adolescent artistic gymnasts during a competitive season. Method...
Background: Caloric restriction (CR) is a dietary intervention based on limiting calories relative to the basic energy needs of the organism, which changes the intensity of metabolism, causes changes in the functioning of the endocrine and sympatheti...
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial joint inflammation and different system involvement that results in considerable physical and psychological symptoms. This narrative review investigates the impacts o...
Background: Phase angle (PhA), derived from bioelectrical impedance analysis (BIA), is a non-invasive parameter that reflects cellular integrity and nutritional status. Although PhA is increasingly used in pediatric settings, evidence on modifiable d...
Background: Sleep quality (SQ) and physical activity (PA) are among the strongest behavioral determinants of healthy aging, while dietary behavior and psychological factors act as complementary modulators of these relationships. Although each domain...
Objectives: Malnutrition can influence perioperative complications and long-term survival in patients with gastrointestinal (GI) cancers. Oral functional decline is associated with decreased food intake, and a reduced number of remaining teeth contri...
Background/Objectives: Gestational diabetes mellitus (GDM) is one of the most common metabolic complications during pregnancy. Nutritional and diabetological education constitutes the cornerstone of treatment; however, its actual impact according to...
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