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  • Article
  • Open Access

23 January 2026

Background: “Healthy Life Longevity” (a latent variable) is defined as the number of survival days, along with recommended subjective health and long-term care needs. This study aimed to clarify the structural relationships among several...

  • Article
  • Open Access

Kaempferol Inhibits MMP-1-Mediated Migration and Invasion in Gemcitabine-Resistant Pancreatic Cancer Cells

  • Saburo Sugita,
  • Yoichi Matsuo,
  • Masaki Ishida,
  • Yuriko Uehara,
  • Yuki Eguchi,
  • Yuki Denda,
  • Keisuke Nonoyama,
  • Hiromichi Murase,
  • Tomokatsu Kato and
  • Shuji Takiguchi
  • + 7 authors

23 January 2026

Background: Pancreatic cancer (PaCa) has an extremely poor prognosis. This malignancy rapidly acquires resistance to gemcitabine (GEM), a key chemotherapeutic agent, yet the mechanisms underlying this resistance remain incompletely understood. We pre...

  • Article
  • Open Access

23 January 2026

Background/Objectives: This study aimed to explore the association between maternal gut microbiota and metabolic profiles in the first trimester and the subsequent risk of gestational diabetes mellitus (GDM), as well as to characterize association pa...

  • Review
  • Open Access

Rethinking Energy Availability from Conceptual Models to Applied Practice: A Narrative Review

  • Sergio Espinar,
  • Marina A. Sánchez-Fernández,
  • Juan J. Martin-Olmedo,
  • Marcos Rueda-Córdoba and
  • Lucas Jurado-Fasoli

23 January 2026

Background/Objectives: Energy availability (EA), defined as the dietary energy remaining after exercise energy expenditure (EEE), is a central determinant of both health and performance in athletes. Chronic insufficient EA leads to low energy availab...

  • Review
  • Open Access

Effects of Epigallocatechin Gallate Against Lung Cancer: Mechanisms of Action and Therapeutic Potential

  • Dordaneh Mirbabaei Ghafghazi,
  • Newman Siu Kwan Sze and
  • Evangelia Tsiani

23 January 2026

Epigallocatechin-3-gallate (EGCG), the major bioactive polyphenol in green tea, has garnered significant attention for its potential anticancer properties. This review summarizes the current evidence from in vitro, in vivo, and clinical trials examin...

  • Article
  • Open Access

Evaluation of the Relationship Between Orexin A, Peptide YY, AgRP, and POMC Levels and Sleep Disorders in Children with Malnutrition

  • Anna Carina Ergani,
  • Mustafa Esad Tezcan,
  • Ümmügülsüm Can and
  • Emine Arslan Kılıçoğlu

23 January 2026

Background: Malnutrition and sleep disturbances are common in childhood and are associated with neuropeptides that regulate appetite and circadian rhythms. Hypothalamic peptides such as orexin A, agouti-related protein (AgRP), proopiomelanocortin (PO...

  • Article
  • Open Access

Bioelectrical Impedance and GLIM Criteria Identify Early Nutritional Deterioration and Mortality in Acute Leukemia Patients Undergoing Chemotherapy

  • Lara Dalla Rovere,
  • María José Tapia Guerrero,
  • Viyey K. Doulatram-Gamgaram,
  • María Garcia-Olivares,
  • Belén del Arco-Romualdo,
  • Montserrat Gonzalo-Marín,
  • María Rosario Vallejo Mora,
  • Daniel Barrios Decoud,
  • Carola Díaz Aizpún and
  • Gabriel Olveira
  • + 5 authors

23 January 2026

Background/Objectives: Malnutrition is highly prevalent in patients with acute leukemia and is frequently underrecognized at diagnosis. Traditional screening tools based on anthropometry often fail to identify early nutritional deterioration. This st...

  • Article
  • Open Access

Functional Phytochemicals Cooperatively Suppress Inflammation in RAW264.7 Cells

  • Kaori Terashita,
  • Masato Kohakura,
  • Katsura Sugawara,
  • Shinichi Miyagawa and
  • Gen-ichiro Arimrua

23 January 2026

Background: Chronic inflammation contributes to the development of lifestyle-related diseases, and dietary phytochemicals are recognized as important modulators of inflammatory responses. However, the synergistic anti-inflammatory effects of phytoche...

  • Article
  • Open Access

“I Was Thinking About Food All the Time, I Didn’t Have Enough”: Understanding the Multidimensional Nature of Food Insecurity Among Undergraduates at an Urban U.S. Campus

  • Gabby Headrick,
  • Julia Blouin,
  • Mackenzie Konyar,
  • Lily Amorosino,
  • Matea Mandic,
  • Anna Razvi,
  • Kaleigh Steigman,
  • Sean Watley,
  • Douglas Frazier and
  • Jennifer Sacheck

23 January 2026

Background: Food insecurity among college students is a multidimensional challenge shaped by individual, interpersonal, institutional, community, and policy factors. Although many campuses require or provide meal plans, students may experience food i...

  • Article
  • Open Access

Antenatal Care Attendance and Multiple Micronutrient Supplementation Intake: Perspectives from Women and Antenatal Care Service Providers in Rwanda

  • Giulia Pastori,
  • Kesso Gabrielle van Zutphen-Küffer,
  • Shashank Sarvan,
  • Yana Manyuk,
  • Elvis Gakuba,
  • Yashodhara Rana,
  • Jack Clift,
  • Kara Weiss,
  • Bonnie Weiss and
  • Sufia Askari
  • + 6 authors

23 January 2026

Background/Objectives: Emerging evidence suggests that multiple micronutrient supplements (MMS) provide additional benefits for maternal and neonatal health compared with iron and folic acid (IFA) supplements. To achieve effective coverage, acceptabi...

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Nutrients - ISSN 2072-6643