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  • Article
  • Open Access
8 Citations
3,515 Views
16 Pages

Psychopathological Influences on Surgical and Clinical Outcomes in Lumbar Disk Herniation: Prediction Models and Literature Analysis

  • Gianluca Galieri,
  • Vittorio Orlando,
  • Edoardo Mazzucchi,
  • Fabrizio Pignotti and ,
  • Davide Cusumano,
  • Paola Bazzu,
  • Sofia Mantini,
  • Roberto Altieri,
  • Manlio Barbarisi and
  • Giuseppe La Rocca
  • + 7 authors+ 2 authors

26 January 2025

Background/Objectives: Lumbar disk herniation (LDH) significantly affects quality of life due to lower back and radiating leg pain. Surgical intervention, such as discectomy, is effective for symptom relief when conservative measures fail; however, p...

(This article belongs to the Special Issue Orthopedic Trauma: New Perspectives and Innovative Techniques)
  • Article
  • Open Access
378 Views
21 Pages

Exenterative Surgery in Advanced Pelvic Cancer: Survival Outcomes and an Exploratory Predictive Modeling Framework for Surgical Decision Support

  • Elena Chitoran,
  • Vlad Rotaru,
  • Aisa Gelal,
  • Daniela-Cristina Stefan and ,
  • Giuseppe Gullo,
  • Traian Patrascu and
  • Laurentiu Simion
  • + 2 authors+ 0 author

16 August 2026

Background/Objectives: Pelvic exenteration is among the most aggressive procedures in surgical oncology and remains associated with substantial morbidity and highly variable oncologic outcomes. Achieving negative resection margins (R0) is the stronge...

(This article belongs to the Special Issue Abdominal Diseases: Diagnosis, Treatment and Management—2nd Edition)
  • Article
  • Open Access
5 Citations
3,962 Views
14 Pages

Integrating Machine Learning and Deep Learning for Predicting Non-Surgical Root Canal Treatment Outcomes Using Two-Dimensional Periapical Radiographs

  • Catalina Bennasar,
  • Antonio Nadal-Martínez,
  • Sebastiana Arroyo,
  • Yolanda Gonzalez-Cid and ,
  • Ángel Arturo López-González and
  • Pedro Juan Tárraga
  • + 1 author+ 0 author

Background/Objectives: In a previous study, we utilized categorical variables and machine learning (ML) algorithms to predict the success of non-surgical root canal treatments (NSRCTs) in apical periodontitis (AP), classifying the outcome as either s...

(This article belongs to the Special Issue Machine-Learning-Based Disease Diagnosis and Prediction)
  • Review
  • Open Access
33 Citations
9,047 Views
20 Pages

Glaucoma is a leading cause of irreversible blindness, with challenges persisting in early diagnosis, disease progression, and surgical outcome prediction. Recent advances in artificial intelligence have enabled significant progress by extracting cli...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Review
  • Open Access
1 Citations
2,082 Views
15 Pages

The Role of Artificial Intelligence in Orthognathic Surgery: A Scoping Review

  • Katarína Janáková,
  • Barbora Heribanová,
  • Juraj Tomášik,
  • Daniela Tichá and ,
  • Martin Strunga,
  • Andrej Janák,
  • Kristián Šimko and
  • Andrej Thurzo
  • + 3 authors+ 0 author

11 May 2026

Background/Objectives: Artificial intelligence (AI) has gained growing interest in the field of orthognathic surgery due to its potential to improve diagnostic accuracy, surgical planning, and treatment outcomes. This scoping review maps literature f...

(This article belongs to the Special Issue Feature Papers in Digital Dentistry)
  • Article
  • Open Access
2 Citations
1,669 Views
15 Pages

21 November 2025

Facial reconstructive surgery requires precise preoperative planning to optimize functional and aesthetic outcomes, but current imaging technologies like CT and MRI do not offer visualization of expected post-surgical appearance, limiting surgical pl...

(This article belongs to the Special Issue Artificial Intelligence Applications in Healthcare and Precision Medicine, 2nd Edition)
  • Article
  • Open Access
1 Citations
1,803 Views
18 Pages

Machine Learning Modeling of Hospital Length of Stay After Breast Cancer Surgery: Comparison of Random Forest and Linear Regression Approaches

  • Iulian Slavu,
  • Raluca Tulin,
  • Alexandru Dogaru,
  • Ileana Dima and ,
  • Cristina Orlov Slavu,
  • Daniela-Elena Gheoca Mutu and
  • Adrian Tulin
  • + 2 authors+ 0 author

31 December 2025

Background and Objectives: Hospital length of stay (LOS) after breast cancer surgery is a key indicator of postoperative recovery, healthcare quality, and hospital resource utilization. Traditional statistical approaches have identified general corre...

  • Article
  • Open Access
3 Citations
1,426 Views
16 Pages

Perioperative Risk Prediction in Major Gynaecological Oncology Surgery: A National Diagnostic Survey of UK Clinical Practice

  • Lusine Sevinyan,
  • Anil Tailor,
  • Pradeep Prabhu,
  • Peter Williams and ,
  • Melanie Flint and
  • Thumuluru Kavitha Madhuri
  • + 1 author+ 0 author

Background: Gynaecological oncology (GO) surgery involves a wide range of procedures, from minor diagnostic interventions to highly complex cytoreductive operations. Accurate perioperative diagnostics—particularly in major surgery—are cri...

(This article belongs to the Special Issue New Insights into the Diagnosis of Gynecological Diseases)
  • Review
  • Open Access
6 Citations
3,796 Views
39 Pages

Intelligence Architectures and Machine Learning Applications in Contemporary Spine Care

  • Rahul Kumar,
  • Conor Dougherty,
  • Kyle Sporn,
  • Akshay Khanna and ,
  • Puja Ravi,
  • Pranay Prabhakar and
  • Nasif Zaman
  • + 2 authors+ 0 author

The rapid evolution of artificial intelligence (AI) and machine learning (ML) technologies has initiated a paradigm shift in contemporary spine care. This narrative review synthesizes advances across imaging-based diagnostics, surgical planning, geno...

(This article belongs to the Special Issue Artificial Intelligence and Machine Learning in Spine Research)
  • Article
  • Open Access
13 Citations
5,348 Views
10 Pages

Second Opinion for Non-Surgical Root Canal Treatment Prognosis Using Machine Learning Models

  • Catalina Bennasar,
  • Irene García,
  • Yolanda Gonzalez-Cid,
  • Francesc Pérez and
  • Juan Jiménez

23 August 2023

Although the association between risk factors and non-surgical root canal treatment (NSRCT) failure has been extensively studied, methods to predict the outcomes of NSRCT are in an early stage, and dentists currently make the treatment prognosis base...

(This article belongs to the Special Issue Artificial Intelligence in Clinical Decision Support)
  • Article
  • Open Access
11 Citations
3,796 Views
13 Pages

Machine Learning Prediction of Visual Outcome after Surgical Decompression of Sellar Region Tumors

  • Nidan Qiao,
  • Yichen Ma,
  • Xiaochen Chen,
  • Zhao Ye and ,
  • Hongying Ye,
  • Zhaoyun Zhang,
  • Yongfei Wang,
  • Zhaozeng Lu,
  • Zhiliang Wang and
  • Yao Zhao
  • + 6 authors+ 1 author

25 January 2022

Introduction: This study aims to develop a machine learning-based model integrating clinical and ophthalmic features to predict visual outcomes after transsphenoidal resection of sellar region tumors. Methods: Adult patients with optic chiasm compres...

(This article belongs to the Special Issue Non-communicable Diseases, Big Data and Artificial Intelligence)
  • Review
  • Open Access
30 Citations
13,378 Views
29 Pages

Prediction of Surgical Outcome in Advanced Ovarian Cancer by Imaging and Laparoscopy: A Narrative Review

  • Patrícia Pinto,
  • Andrea Burgetova,
  • David Cibula,
  • Ingfrid S. Haldorsen and ,
  • Tereza Indrielle-Kelly and
  • Daniela Fischerova
  • + 1 author+ 0 author

22 March 2023

Maximal-effort upfront or interval debulking surgery is the recommended approach for advanced-stage ovarian cancer. The role of diagnostic imaging is to provide a systematic and structured report on tumour dissemination with emphasis on key sites for...

(This article belongs to the Special Issue Gynaecological Cancer and Surgery: Current Practice, Novel Technologies and Future Developments)
  • Article
  • Open Access
14 Citations
3,535 Views
10 Pages

Endoscopic Endonasal Repair of Congenital Choanal Atresia: Predictive Factors of Surgical Stability and Healing Outcomes

  • Salvatore Ferlito,
  • Antonino Maniaci,
  • Alberto Giulio Dragonetti,
  • Salvatore Cocuzza and ,
  • Jerome Rene Lechien,
  • Christian Calvo-Henríquez,
  • Juan Maza-Solano,
  • Luca Giovanni Locatello,
  • Sebastiano Caruso and
  • Ignazio La Mantia
  • + 11 authors+ 6 authors

Background: To assess the long-term outcomes and independent predictors of surgical success of a one-stage minimally invasive surgical procedure for congenital choanal atresia (C.C.A.). Methods: a retrospective multicentric study was conducted betwee...

(This article belongs to the Section Health Behavior, Chronic Disease and Health Promotion)
  • Article
  • Open Access
1,554 Views
13 Pages

Development and Validation of a Site-Specific Tumor Burden Score for Predicting Surgical Outcomes in Advanced Ovarian Cancer

  • Zhiyang Xu,
  • Xiaotian Li,
  • Ying Liu,
  • Yongqiang Tang and ,
  • Weihuan Hou,
  • Yihua Jin,
  • Gaijing Cao,
  • Lingxia Li,
  • Hongxi Zhao and
  • Shujuan Liu
  • + 6 authors+ 1 author

13 November 2025

Objective: The relationship between surgical outcomes and metastatic sites in ovarian cancer (OC) is known, but the role of metastatic site-specific tumor burden remains unclear. Methods: We prospectively analyzed data from 202 OC patients. We develo...

(This article belongs to the Section Cancer Causes, Screening and Diagnosis)
  • Article
  • Open Access
13 Citations
3,360 Views
16 Pages

Outcome Prediction of Spontaneous Supratentorial Intracerebral Hemorrhage after Surgical Treatment Based on Non-Contrast Computed Tomography: A Multicenter Study

  • Kangwei Zhang,
  • Xiang Zhou,
  • Qian Xi,
  • Xinyun Wang and ,
  • Baoqing Yang,
  • Jinxi Meng,
  • Ming Liu,
  • Ningxin Dong,
  • Xiaofen Wu and
  • Peijun Wang
  • + 7 authors+ 2 authors

16 February 2023

This study aims to explore the value of a machine learning (ML) model based on radiomics features and clinical features in predicting the outcome of spontaneous supratentorial intracerebral hemorrhage (sICH) 90 days after surgery. A total of 348 pati...

(This article belongs to the Special Issue Computational Neuroradiology and AI in Neuroradiology)
  • Article
  • Open Access
10 Citations
2,609 Views
9 Pages

The BETTY Score to Predict Perioperative Outcomes in Surgical Patients

  • Michael Baboudjian,
  • Rawad Abou-Zahr,
  • Bogdan Buhas,
  • Alae Touzani and ,
  • Jean-Baptiste Beauval and
  • Guillaume Ploussard
  • + 1 author+ 0 author

4 June 2023

The aim of this study is to evaluate a new user-friendly scoring system, namely the BETTY score, that aims to predict 30-day patient outcomes after surgery. In this first description, we rely on a population of prostate cancer patients undergoing rob...

(This article belongs to the Special Issue Prognostic Factors in Urologic Cancers—Assessment and Integration into Clinical Care)
  • Article
  • Open Access
1 Citations
2,712 Views
18 Pages

Does Baseline Hounsfield Unit Predict Patients’ Outcomes Following Surgical Management of Unstable Osteoporotic Thoracolumbar Fractures?

  • Ahmed Qretam,
  • Julien Ceuterick,
  • Maher Ghandour,
  • Ümit Mert and ,
  • Christian Herren,
  • Miguel Pishnamaz,
  • Matthias Knobe,
  • Frank Hildebrand,
  • Rolf Sobottke and
  • Mohamad Agha Mahmoud
  • + 5 authors+ 0 author

27 January 2025

Background and Objectives: Osteoporotic fractures in the thoracic/lumbar spine pose significant challenges in surgical management, with high risks of complications. This study investigates the role of preoperative CT scans and Hounsfield Units (HUs)...

(This article belongs to the Special Issue New Strategies in the Management of Geriatric Bone Fracture)
  • Article
  • Open Access
1 Citations
1,964 Views
8 Pages

The Predictability of the Surgical Outcomes of Class III Patients in the Transverse Dimension—A Study of Three-Dimensional Assessment

  • U-Kei Lai,
  • Cheng-Chun Wu,
  • Yu-Jen Chang,
  • Shiu-Shiung Lin and ,
  • Jui-Pin Lai and
  • Te-Ju Wu
  • + 1 author+ 0 author

15 July 2022

This study aimed to assess the outcomes of planned maxillary surgical movements in the transverse direction in patients possessing a Class III skeletal pattern. The available consecutive patients’ records were retrospectively reviewed. Only tho...

(This article belongs to the Special Issue Prevention and Management of Oral Healthcare)
  • Article
  • Open Access
584 Views
16 Pages

Deep Learning Analysis of Intraoperative Physiological Signals for Predicting Surgical Outcomes in Head and Neck Free Flap Surgery: Preliminary Study

  • Ji Won Kim,
  • Jae Yeong Kim,
  • Hanaro Park,
  • Soon-Hyun Ahn and ,
  • Eun-Jae Chung and
  • Jungirl Seok
  • + 1 author+ 0 author

4 August 2026

Intraoperative monitoring systems play a vital role in surgical safety and decision-making. This study explored whether high-resolution physiological signals routinely available during surgery can be leveraged by deep learning to predict adverse even...

  • Article
  • Open Access
1 Citations
3,781 Views
12 Pages

Prediction of Surgical Outcome by Tumor Volume Doubling Time via Stereo Imaging Software in Early Non-Small Cell Lung Cancer

  • Chia-Chi Liu,
  • Ya-Fu Cheng,
  • Pei-Cing Ke,
  • Yi-Ling Chen and ,
  • Ching-Min Lin and
  • Bing-Yen Wang
  • + 1 author+ 0 author

3 August 2023

Background: Volume doubling time (VDT) has been proven to be a powerful predictor of lung cancer progression. In non-small cell lung cancer patients receiving sublobar resection, the discussion of correlation between VDT and surgery was absent. We pr...

(This article belongs to the Special Issue Advances in Oncological Imaging)
  • Article
  • Open Access
17 Citations
3,948 Views
13 Pages

Machine Learning Models to Predict Survival Outcomes According to the Surgical Approach of Primary Radical Hysterectomy in Patients with Early Cervical Cancer

  • Se Ik Kim,
  • Sungyoung Lee,
  • Chel Hun Choi,
  • Maria Lee and ,
  • Dong Hoon Suh,
  • Hee Seung Kim,
  • Kidong Kim,
  • Hyun Hoon Chung,
  • Jae Hong No and
  • Yong Beom Kim
  • + 8 authors+ 3 authors

23 July 2021

We purposed to develop machine learning models predicting survival outcomes according to the surgical approach for radical hysterectomy (RH) in early cervical cancer. In total, 1056 patients with 2009 FIGO stage IB cervical cancer who underwent prima...

  • Article
  • Open Access
40 Citations
5,094 Views
14 Pages

Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes

  • Anish G. Potty,
  • Ajish S. R. Potty,
  • Nicola Maffulli,
  • Lucas A. Blumenschein and ,
  • Deepak Ganta,
  • R. Justin Mistovich,
  • Mario Fuentes,
  • Patrick J. Denard,
  • Paul M. Sethi and
  • Ashim Gupta
  • + 6 authors+ 1 author

19 March 2023

Machine learning (ML) has not yet been used to identify factors predictive for post-operative functional outcomes following arthroscopic rotator cuff repair (ARCR). We propose a novel algorithm to predict ARCR outcomes using machine learning. This is...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
1 Citations
572 Views
29 Pages

24 July 2026

Background and Objectives: Pediatric appendicitis remains a common surgical emergency, but early risk stratification of complicated appendicitis and expected hospital length of stay (LOS) remains challenging. This study developed and internally evalu...

(This article belongs to the Section Pediatrics)
  • Article
  • Open Access
8 Citations
2,072 Views
17 Pages

Planned and Unplanned Sarcoma Resections: Comparative Analysis of Local Recurrence, Metastasis, and Mortality

  • Kim N. Nydegger,
  • Timothy T. A. F. Obergfell,
  • Philip Heesen,
  • Georg Schelling and ,
  • Gabriela Studer,
  • Beata Bode-Lesniewska and
  • Bruno Fuchs
  • + 2 authors+ 0 author

7 October 2024

Background: Sarcomas, a diverse group of malignant tumors arising from mesenchymal tissues, pose significant diagnostic and therapeutic challenges. This study compares the outcomes of planned resections (PEs) and unplanned resections (UEs) to inform...

(This article belongs to the Section Methods and Technologies Development)
  • Article
  • Open Access
3 Citations
2,741 Views
13 Pages

Effectiveness of Global Optimisation and Direct Kinematics in Predicting Surgical Outcome in Children with Cerebral Palsy

  • Claude Fiifi Hayford,
  • Emma Pratt,
  • John P. Cashman,
  • Owain G. Evans and
  • Claudia Mazzà

27 November 2021

Multibody optimisation approaches have not seen much use in routine clinical applications despite evidence of improvements in modelling through a reduction in soft tissue artifacts compared to the standard gait analysis technique of direct kinematics...

(This article belongs to the Special Issue Modelling and Simulation of Human Locomotion)
  • Article
  • Open Access
851 Views
10 Pages

30 November 2025

Background and Objective: Placenta Accreta Spectrum (PAS) encompasses a continuum of abnormal placentation conditions associated with significant maternal and fetal morbidity. Management of PAS requires coordinated cesarean hysterectomy. Associated m...

(This article belongs to the Section Obstetrics and Gynecology)
  • Article
  • Open Access
16 Citations
3,143 Views
16 Pages

A Frailty-Adjusted Stratification Score to Predict Surgical Risk, Post-Operative, Long-Term Functional Outcome, and Quality of Life after Surgery in Intracranial Meningiomas

  • Leonardo Tariciotti,
  • Giorgio Fiore,
  • Sara Carapella,
  • Luigi Gianmaria Remore and ,
  • Luigi Schisano,
  • Stefano Borsa,
  • Mauro Pluderi,
  • Marco Canevelli,
  • Giovanni Marfia and
  • Giulio Bertani
  • + 7 authors+ 2 authors

22 June 2022

Object: To investigate those parameters affecting early and follow-up functional outcomes in patients undergoing resection of meningiomas and to design a dedicated predictive score, the Milan Bio(metric)-Surgical Score (MBSS) is hereby presented. Met...

(This article belongs to the Special Issue Meningioma Surgery and Functional Outcome)
  • Article
  • Open Access
1 Views
4 Pages

Factors Influencing Surgical Outcome after Anterior Stabilization of the Cervical Spine with Heterogeneous Material

  • Athanasios K. Petridis,
  • Sabrina Sechting,
  • Michael Budde,
  • Alexandros Doukas and ,
  • Homajoun Maslehaty and
  • Hubertus Maximilian Mehdorn
  • + 1 author+ 0 author

Intervertebral fusion through an anterior approach with polymethylacrylate is a wellestablished neurosurgical technique in the treatment of cervical spine degeneration. However, questions still remain concerning the post-surgical outcome. Factors inf...

  • Article
  • Open Access
8 Citations
2,862 Views
12 Pages

Can Presurgical Interhemispheric EEG Connectivity Predict Outcome in Hemispheric Surgery? A Brain Machine Learning Approach

  • Chiara Pepi,
  • Mattia Mercier,
  • Giusy Carfì Pavia,
  • Alessandro de Benedictis and ,
  • Federico Vigevano,
  • Maria Camilla Rossi-Espagnet,
  • Giovanni Falcicchio,
  • Carlo Efisio Marras,
  • Nicola Specchio and
  • Luca de Palma
  • + 5 authors+ 0 author

30 December 2022

Objectives: Hemispherotomy (HT) is a surgical option for treatment of drug-resistant seizures due to hemispheric structural lesions. Factors affecting seizure outcome have not been fully clarified. In our study, we used a brain Machine Learning (ML)...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Article
  • Open Access
6 Citations
6,178 Views
11 Pages

25 September 2022

We investigated factors that affect the surgical outcomes of robotic pyeloplasty by comparing the surgical results of pediatric and adult patients with ureteropelvic junction stricture (UPJO). We retrospectively reviewed patients who underwent roboti...

(This article belongs to the Special Issue Robot-Assisted Surgery in Urology)
  • Article
  • Open Access
14 Citations
5,274 Views
12 Pages

Examination of Prognostic Factors Affecting Long-Term Survival of Patients with Stage 3/4 Gallbladder Cancer without Distant Metastasis

  • Ryota Higuchi,
  • Takehisa Yazawa,
  • Shuichirou Uemura,
  • Yutaro Matsunaga and ,
  • Takehiro Ota,
  • Tatsuo Araida,
  • Toru Furukawa and
  • Masakazu Yamamoto
  • + 3 authors+ 0 author

27 July 2020

In advanced gallbladder cancer (GBC) radical resection, if multiple prognostic factors are present, the outcome may be poor; however, the details remain unclear. To investigate the poor prognostic factors affecting long-term surgical outcome, we exam...

(This article belongs to the Special Issue Research Progress of Biliary Tract Cancers)
  • Article
  • Open Access
2 Citations
2,189 Views
10 Pages

Post-Operative Outcome Predictions in Vestibular Schwannoma Using Machine Learning Algorithms

  • Abigail Dichter,
  • Khushi Bhatt,
  • Mohan Liu,
  • Timothy Park and ,
  • Hamid R. Djalilian and
  • Mehdi Abouzari
  • + 1 author+ 0 author

22 December 2024

Background/Objectives: This study aimed to develop a machine learning (ML) algorithm that can predict unplanned reoperations and surgical/medical complications after vestibular schwannoma (VS) surgery. Methods: All pre- and peri-operative variables a...

(This article belongs to the Section Personalized Therapy in Clinical Medicine)
  • Feature Paper
  • Article
  • Open Access
6 Citations
2,908 Views
10 Pages

External Validation of Prediction Models for Surgical Complications in People Considering Total Hip or Knee Arthroplasty Was Successful for Delirium but Not for Surgical Site Infection, Postoperative Bleeding, and Nerve Damage: A Retrospective Cohort Study

  • Lieke Sweerts,
  • Pepijn W. Dekkers,
  • Philip J. van der Wees,
  • Job L. C. van Susante and ,
  • Lex D. de Jong,
  • Thomas J. Hoogeboom and
  • Sebastiaan A. W. van de Groes
  • + 2 authors+ 0 author

31 January 2023

Although several models for the prediction of surgical complications after primary total hip or total knee replacement (THA and TKA, respectively) are available, only a few models have been externally validated. The aim of this study was to externall...

(This article belongs to the Special Issue Cutting-Edge in Arthroplasty: Before, While and after Surgery)
  • Systematic Review
  • Open Access
5 Citations
3,730 Views
15 Pages

Methods for Identifying Epilepsy Surgery Targets Using Invasive EEG: A Systematic Review

  • Karla Ivankovic,
  • Alessandro Principe,
  • Riccardo Zucca,
  • Mara Dierssen and
  • Rodrigo Rocamora

13 November 2024

Background: The pre-surgical evaluation for drug-resistant epilepsy achieves seizure freedom in only 50–60% of patients. Efforts to identify quantitative intracranial EEG (qEEG) biomarkers of epileptogenicity are needed. This review summarizes...

(This article belongs to the Special Issue Epilepsy: From Mechanisms to Therapeutic Approaches)
  • Article
  • Open Access
1,411 Views
16 Pages

The Role of Background Activity Monitoring by Amplitude-Integrated EEG to Predict Short-Term Neurological Outcome in Neonates with Congenital Heart Disease: Insights from a Real-Life Retrospective Cohort

  • Massimo Mastrangelo,
  • Salvatore Mazzeo,
  • Eleonora Ferrante,
  • Giulia Bruschi and ,
  • Gianni Cutillo,
  • Elisa Bortolin,
  • Alessandro Bombaci,
  • Irene Borzillo,
  • Giuseppe Isgrò and
  • Maria Salsone
  • + 9 authors+ 4 authors

Neonates undergoing surgery for congenital heart disease (CHD) are at high risk for brain function impairment. Reliable early predictors of postoperative neurological complications are lacking. We examined a retrospective cohort of 55 surgically trea...

  • Article
  • Open Access
17 Citations
4,097 Views
13 Pages

Evaluating Computer Vision, Large Language, and Genome-Wide Association Models in a Limited Sized Patient Cohort for Pre-Operative Risk Stratification in Adult Spinal Deformity Surgery

  • Ethan Schonfeld,
  • Aaradhya Pant,
  • Aaryan Shah,
  • Sina Sadeghzadeh and ,
  • Dhiraj Pangal,
  • Adrian Rodrigues,
  • Kelly Yoo,
  • Neelan Marianayagam,
  • Ghani Haider and
  • Anand Veeravagu
  • + 5 authors+ 0 author

23 January 2024

Background: Adult spinal deformities (ASD) are varied spinal abnormalities, often necessitating surgical intervention when associated with pain, worsening deformity, or worsening function. Predicting post-operative complications and revision surgery...

(This article belongs to the Special Issue Advances in Scoliosis, Spinal Deformity and Other Spinal Disorders)
  • Review
  • Open Access
11 Citations
4,172 Views
18 Pages

MicroRNAs as Biomarkers of Surgical Outcome in Mesial Temporal Lobe Epilepsy: A Systematic Review

  • Alexey M. Yakimov,
  • Elena E. Timechko,
  • Irina G. Areshkina,
  • Anna A. Usoltseva and ,
  • Kristina D. Yakovleva,
  • Elena A. Kantimirova,
  • Nikita Utyashev,
  • Nikita Ivin and
  • Diana V. Dmitrenko
  • + 4 authors+ 0 author

Mesial temporal lobe epilepsy is the most common type of epilepsy. For most patients suffering from TLE, the only treatment option is surgery. However, there is a high possibility of relapse. Invasive EEG as a method for predicting the outcome of sur...

(This article belongs to the Special Issue RNA Regulatory Networks at the Crossroad of Human Diseases 3.0)
  • Article
  • Open Access
8 Citations
4,186 Views
16 Pages

Individualized prediction of postoperative ambulatory status for patients with intertrochanteric fractures is clinically relevant, during both preoperative and intraoperative periods. This study intended to develop clinical prediction rules (CPR) to...

(This article belongs to the Special Issue Musculoskeletal Disorders, Physical Rehabilitation and Health)
  • Article
  • Open Access
6 Citations
5,310 Views
12 Pages

The Outcome of Surgical Treatment for the Neuropathic Diabetic Foot Lesions—A Single-Center Study

  • Florin Bobirca,
  • Catalin Gabriel Smarandache,
  • Anca Bobirca,
  • Cristina Alexandru and ,
  • Dan Dumitrescu,
  • Anca Pantea Stoian,
  • Cristina Bica,
  • Lacramioara Aurelia Brinduse,
  • Anca Musetescu and
  • Ioan Ancuta
  • + 7 authors+ 2 authors

29 July 2022

The prevalence of diabetic foot complications is continuously increasing as diabetes has become one of the most important “epidemics” of our time. The main objective of this study was to describe the appropriate surgical intervention for...

(This article belongs to the Special Issue Peripheral Diabetic Neuropathy: Symptoms, Causes and Treatment)
  • Article
  • Open Access
25 Citations
3,749 Views
14 Pages

28 January 2023

Background: Preoperative prediction of short-term postoperative outcomes in spinal tumor patients can lead to more precise patient care plans that reduce the likelihood of negative outcomes. With this study, we aimed to develop machine learning algor...

(This article belongs to the Topic Artificial Intelligence in Cancer, Biology and Oncology)
  • Article
  • Open Access
15 Citations
5,813 Views
12 Pages

7 August 2019

Background and Objectives: We aimed to identify prognostic computed tomography (CT) findings in retrofenestral otosclerosis, with particular attention paid to the role of otosclerotic lesion area in predicting post-stapedotomy outcome. Materials and...

(This article belongs to the Special Issue Therapies for Hearing Loss)
  • Article
  • Open Access
1 Citations
643 Views
18 Pages

22 April 2026

Background/Objective: Postoperative recovery after spine surgery varies substantially and cannot be fully explained by structural pathology alone. This study evaluates postoperative outcomes using a structured 2 × 2 Surgical Trauma Gradient int...

(This article belongs to the Special Issue Clinical Progress of Spine Surgery)
  • Communication
  • Open Access
7 Citations
1,680 Views
8 Pages

The Liver Transection Area Is a Novel Predictor for Surgical Difficulty in Laparoscopic Liver Resection

  • Motohiko Yamada,
  • Kosei Takagi,
  • Tomokazu Fuji,
  • Kazuya Yasui and ,
  • Jiro Kimura,
  • Takeyoshi Nishiyama,
  • Yasuo Nagai,
  • Noriyuki Kanehira and
  • Toshiyoshi Fujiwara
  • + 4 authors+ 0 author

24 September 2024

Background: A difficulty scoring system was developed to estimate the surgical outcomes of laparoscopic liver surgery (LLS); however, the effect of the liver transection area (LTA) on LLS outcomes have not been previously examined. Therefore, this st...

(This article belongs to the Section General Surgery)
  • Article
  • Open Access
3 Citations
1,466 Views
12 Pages

The Role of Preoperative Immunonutritional Scores in Predicting Complications After Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease

  • Marina Raguž,
  • Marko Tarle,
  • Petar Marčinković,
  • Hana Chudy and ,
  • Darko Orešković,
  • Vladimira Vuletić,
  • Tonko Marinović and
  • Darko Chudy
  • + 3 authors+ 0 author

29 May 2025

Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder associated with systemic inflammation, immune dysregulation, and malnutrition, all of which may influence surgical outcomes. Subthalamic nucleus deep brain stimula...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
1 Citations
3,859 Views
16 Pages

Background/Objectives: This study aims to evaluate factors influencing revision cochlear implant surgeries, including patient demographics, surgical techniques, and radiological findings. The main aim was to identify factors influencing surgical succ...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Review
  • Open Access
978 Views
23 Pages

Risk Factors and Predictive Biomarkers for Postoperative Complications in Crohn’s Disease Surgery: Systematic Review

  • Bobuțac Eduard,
  • Zaharie Delia Roxana,
  • Vălean Dan,
  • Emil Moiș and ,
  • Călin Popa,
  • Andra Ciocan,
  • Nadim Al-Hajjar and
  • Florin Zaharie
  • + 3 authors+ 0 author

Surgical intervention in Crohn’s disease remains a significant contributor to patient morbidity, with postoperative complication rates reported between 20% and 50%. These complications include a broad spectrum of adverse outcomes, such as surgi...

(This article belongs to the Special Issue Inflammatory Bowel Disease: Molecular Insights—2nd Edition)
  • Article
  • Open Access
9 Citations
2,908 Views
16 Pages

CD34 and CD105 Microvessels in Resected Bone Specimen May Implicate Wound Healing in MRONJ

  • Antonia Marcianò,
  • Antonio Ieni,
  • Rodolfo Mauceri and
  • Giacomo Oteri

Clinical treatment outcome of MRONJ (medication-related osteonecrosis of the jaw) surgery despite radical osseous removal and primary closure healing still shows differences in terms of outcome and disease recurrence. The study aims to assess the rat...

(This article belongs to the Section Health Care Sciences & Services)
  • Article
  • Open Access
5 Citations
1,690 Views
16 Pages

27 June 2025

Background and Objectives: This retrospective cohort study aimed to evaluate the predictive validity of four frailty indices—Modified Frailty Index-5 (mFI-5), Edmonton Frail Scale (EFS), Clinical Frailty Scale (CFS), and Trauma-Specific Frailty...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
6 Citations
3,874 Views
11 Pages

A Comparison of Open Ventral Hernia Repair Risk Stratification Systems: A Call for Consensus

  • Tamás Talpai,
  • Dumitru Sandu Râmboiu,
  • Cătălin Alexandru Pîrvu,
  • Stelian Pantea and ,
  • Mircea Șelaru,
  • Dan Cârțu,
  • Silviu Daniel Preda,
  • Ștefan Pătrașcu,
  • Nicolae Dragoș Mărgăritescu and
  • Valeriu-Marin Șurlin
  • + 6 authors+ 1 author

7 November 2024

Background/Objectives: Ventral hernia repair (VHR) is a common surgical intervention linked to specific surgical site complications. In such occurrences, the related morbidity is often substantial. Although known risk factors have long been recognize...

(This article belongs to the Section Pharmacology)
  • Review
  • Open Access
7 Citations
3,001 Views
14 Pages

Comparative Analysis of Fully Guided and Free-Hand Orthognathic Surgery: Advancements, Precision, and Clinical Outcomes

  • Sophia Tsokkou,
  • Ioannis Konstantinidis,
  • Antonios Keramas,
  • Georgios Kiosis and ,
  • Kanellos Skourtsidis,
  • Danai Alexiou,
  • Georgia-Nektaria Keskesiadou,
  • Sofia Karachrysafi,
  • Theodora Papamitsou and
  • Ioannis Chatzistefanou
  • + 5 authors+ 0 author

11 June 2025

Background/Objectives: Orthognathic surgery has evolved with digital advancements, improving precision and predictability. Traditional free-hand techniques rely on surgeon expertise, often leading to variable outcomes. Fully guided approaches integra...

(This article belongs to the Special Issue Dentistry in the 21st Century: Challenges and Opportunities)

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