Inflammatory Bowel Disease: Molecular Insights—2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 27
Special Issue Editor
2. Charles Perkins Centre, The University of Sydney, Camperdown, Sydney, NSW 2006, Australia
Interests: inflammatory bowel disease; neutrophils; myeloperoxidase; inflammation; colitis; redox biology; antioxidants; reactive oxygen species; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Inflammatory bowel disease is an elusive chronic gastrointestinal inflammatory disease that, in many cases, diminishes the quality of life of patients. While our armamentarium of therapeutic pharmacologies is constantly expanding, our understanding of the molecular underpinnings of this challenging disease lags behind. If we are to progress to curative therapies, we must first define the molecular signatures of IBD at the genetic, biochemical, and immunobiological levels. This will likely include the complex interactions of a multitude of cells, messenger substances, and proteins within the gut environment, immune-related structures, and systemic circulation.
Recent advancements in genomic technologies, high-throughput imaging mass spectrometry, and multiomic analysis have enhanced our understanding of the interplay between endogenous and exogenous factors through newly discovered molecular actors, an improved understanding of microbiome dysbiosis, and the spatial immunocompartmentalisation of the IBD-affected gut. This Special Issue, ‘Inflammatory Bowel Disease: Molecular Insights—2nd Edition’, will further explore these themes.
As a longstanding IBD researcher, it is my pleasure to invite you to contribute to the Special Issue ‘Inflammatory Bowel Disease: Molecular Insights—2nd Edition’ of the International Journal for Molecular Sciences (Impact Factor: 4.9).
We welcome original research manuscripts that help to unravel exciting and novel findings that have the potential to shed light on the pathogenesis of IBD.
The scope of this Special Issue includes research relating to human multiomic analysis, genomic sequencing, studies with components of basic science research or mechanistic data, and animal studies with relevance to Crohn’s disease and/or ulcerative colitis.
I look forward to receiving your original research submissions.
Dr. Belal Chami
Guest Editor
Manuscript Submission Information
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Keywords
- genomic sequencing
- microbiome
- dysbiosis
- commensal flora
- omics
- immunobiology
- colitis
- Crohn’s disease
- ulcerative colitis
- multiomics
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