Abdominal Diseases: Diagnosis, Treatment and Management—2nd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 1588

Special Issue Editor


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Guest Editor
Department of Surgery, Sf. Pantelimon Emergency Clinical Hospital Bucharest, Carol Davila University of Medicine and Pharmacy, 021659 Bucharest, Romania
Interests: pancreatic cancer; acute pancreatitis; abdominal compartment syndrome; FAST, POCUS and pulmonary ultrasound; colorectal cancer; abdominal wall defects: hernias and incisional hernias
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Special Issue Information

Dear Colleagues,

Diagnostics (ISSN 2075-4418) is an international peer-reviewed open access journal on medical diagnosis, published semimonthly online by MDPI. Diagnostics has a Journal Impact Factor of 3.3(2024), and ranks JCR Q1 in the 'Medicine, General and Internal' category. I happily accepted being a Guest Editor for the Special Issue ‘Abdominal Diseases: Diagnosis, Treatment and Management—2nd Edition’ of this valuable journal, and I invite all of you to offer your scientific contributions in abdominal diseases.

Abdominal surgical conditions often raise challenging diagnostic, therapeutic and management issues. The surgeon is often faced with difficult decision-making situations, especially in emergency conditions. Imagistic methods are very useful in diagnostic guidance and are often an important part of image-guided surgery/treatment. Minimally invasive techniques occupy an important aspect, being preferred whenever possible. Laparoscopy is the first choice in most cases. Our defined scope of the topic for this Special Issue is to establish modern management protocols in the diagnosis, treatment and management of abdominal diseases.

Dr. Bogdan Socea
Guest Editor

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Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Publisher’s Notice

The Special Issue, together with its publications, has been shifted from Section Medical Imaging and Theranostics to Section Clinical Diagnosis and Prognosis on 21 April 2026. The publications remain available in the regular issues in which they were originally published. The Editorial Office confirms that these articles adhered to MDPI's standard editorial process (https://www.mdpi.com/editorial_process).

Keywords

  • abdominal diseases
  • abdominal surgery
  • diagnosis
  • image-guided surgery/treatment
  • minimally invasive techniques
  • laparoscopy

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Published Papers (3 papers)

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Research

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14 pages, 636 KB  
Article
Discordance Between Conventional Ultrasound and Transient Elastography in Hepatic Steatosis Assessment: Clinical Factors Associated with Discrepant Findings
by Mihaela Cristina Brisc, Elena Emilia Babeș, Sabina Florina Călugăr-Șolea, Simona Bota, Laura Maghiar, Ciprian Mihai Brisc and Ciprian Brisc
Diagnostics 2026, 16(8), 1188; https://doi.org/10.3390/diagnostics16081188 - 16 Apr 2026
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Abstract
Background: Discrepancies are frequently observed between liver steatosis grading assessed by conventional B-mode ultrasonography and vibration-controlled transient elastography (VCTE) with controlled attenuation parameter (CAP). This study aimed to identify factors associated with these differences and to evaluate whether the two imaging methods [...] Read more.
Background: Discrepancies are frequently observed between liver steatosis grading assessed by conventional B-mode ultrasonography and vibration-controlled transient elastography (VCTE) with controlled attenuation parameter (CAP). This study aimed to identify factors associated with these differences and to evaluate whether the two imaging methods provide comparable steatosis classifications. Methods: We conducted a retrospective cross-sectional observational study including 130 hospitalized patients evaluated over a two-year period who underwent laboratory testing, abdominal ultrasonography, and transient elastography. The analyzed variables included demographic characteristics, nutritional status, comorbidities, and biochemical parameters such as alanine aminotransferase (ALAT), total cholesterol, triglycerides, gamma-glutamyl transferase (GGT), and the fibrosis-4 index (FIB-4). Patients were classified into two groups: concordant steatosis grading between the two methods (n = 61) and discordant results (n = 69). Results: Concordant steatosis grading was more frequently observed in patients with serum total cholesterol > 200 mg/dL (45.9%) and FIB-4 values between 1.45–3.25 (44.2%). A trend toward higher concordance was also observed in patients with elevated triglycerides. In contrast, viral liver disease was significantly associated with discordant results (26.2%). Higher fibrosis stages assessed by VCTE (F ≥ 2) and FIB-4 values > 3.25 showed a non-significant trend toward discordance. Conclusions: Several clinical and biochemical factors influence the agreement between ultrasound and VCTE-based CAP in the assessment of hepatic steatosis. Elevated cholesterol and intermediate FIB-4 values were associated with concordant results, whereas viral liver disease was associated with discordance between the two imaging modalities. Full article
(This article belongs to the Special Issue Abdominal Diseases: Diagnosis, Treatment and Management—2nd Edition)
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17 pages, 897 KB  
Article
Understanding Anastomotic Healing in Colo-Rectal Surgery; a Multicentric 5-Year Analysis of Predictive Factors for Integrity and Fistula Formation
by Dumitru-Dragos Chitca, Octavian Mihalache, Florin Bobircă, Cristian Botezatu, Valentin Popescu, Dan Andras, Maria-Theodora Lapadat, Martina Nichilo, Dragos Eugen Georgescu, Petronel Mustățea, Horia Doran, Bogdan Mastalier and Traian Pătrașcu
Diagnostics 2026, 16(6), 837; https://doi.org/10.3390/diagnostics16060837 - 11 Mar 2026
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Abstract
Background: Anastomotic leakage (AL) remains one of the most feared complications after colorectal surgery. This study aimed to identify preoperative risk factors for AL using a five-year dataset from two Romanian surgical clinics. Materials and Methods: A retrospective cohort of 155 [...] Read more.
Background: Anastomotic leakage (AL) remains one of the most feared complications after colorectal surgery. This study aimed to identify preoperative risk factors for AL using a five-year dataset from two Romanian surgical clinics. Materials and Methods: A retrospective cohort of 155 patients undergoing colorectal resection with primary anastomosis (105 from “Colentina” Hospital and 50 from “Dr. I. Cantacuzino” Hospital) was analyzed. Preoperative demographic, clinical, and laboratory data were extracted and assessed using univariate and multivariable logistic regression. Statistical analyses were performed using IBM SPSS. Results: The overall AL rate was 10.3%. Multivariable analysis identified high ASA class (OR 17.6; p = 0.001), emergency surgery (OR 32.2; p = 0.0007), and heavy alcohol use (OR 15.3; p = 0.004) as independent predictors of leakage. While low preoperative albumin and smoking were associated with leakage in a bivariate analysis, these did not remain significant after adjustment. Notably, all laboratory markers were based on preoperative values, distinguishing our approach from prior studies that commonly evaluated postoperative biomarkers. No statistically significant effect was found for neoadjuvant chemotherapy or radiotherapy after controlling for other covariates. Conclusions: High ASA score, alcohol abuse, and emergency surgery were the strongest independent predictors of AL in our cohort. The lack of predictive power of certain widely reported factors, such as low albumin, may reflect our dataset’s focus on preoperative optimization. These findings support the use of individualized risk assessment and reinforce the role of preoperative preparation in reducing leak incidence in colorectal surgery. Full article
(This article belongs to the Special Issue Abdominal Diseases: Diagnosis, Treatment and Management—2nd Edition)
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Other

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10 pages, 1089 KB  
Case Report
Synchronous Colon Adenocarcinoma and Renal Cell Carcinoma: Diagnostic Challenges and Simultaneous Laparoscopic Management in Two Cases
by Cristian Iorga, Cristina Raluca Iorga and Victor Strambu
Diagnostics 2026, 16(2), 287; https://doi.org/10.3390/diagnostics16020287 - 16 Jan 2026
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Abstract
Background: There is an increasing number of synchronous tumor diagnoses, mainly due to new investigative techniques and diagnostic guidelines. While renal and colonic malignancies are common, synchronous cases remain rare. They are usually diagnosed during the staging work-up performed for the primary cancer. [...] Read more.
Background: There is an increasing number of synchronous tumor diagnoses, mainly due to new investigative techniques and diagnostic guidelines. While renal and colonic malignancies are common, synchronous cases remain rare. They are usually diagnosed during the staging work-up performed for the primary cancer. Case Presentation: We share our experience with two cases of synchronous colon adenocarcinoma and renal cell carcinoma. The surgical intervention was performed simultaneously and laparoscopically, with good results and prognosis. Reviewing the literature, we found few studies reporting these synchronous tumors, which reflects their low incidence. Renal tumors are often identified during imaging studies performed for staging colonic tumors, and performing surgical treatment during the same operation is widely accepted. We performed a search of the literature to identify similar cases and to look for associations that can lead to synchronous colonic and renal malignancies. We also wanted to highlight the potential for therapeutic management as a single step, thereby avoiding a second surgical procedure. Conclusions: Synchronous renal and colonic malignancies are rare and are generally sporadic. Due to their rarity, there are no established guidelines, and management can be challenging. Presently, the treatment needs to be individualized based on discussions from the tumor board. Full article
(This article belongs to the Special Issue Abdominal Diseases: Diagnosis, Treatment and Management—2nd Edition)
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