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258 Results Found

  • Article
  • Open Access
27 Citations
2,398 Views
12 Pages

Probability Score to Predict Spontaneous Conversion to Sinus Rhythm in Patients with Symptomatic Atrial Fibrillation When Less Could Be More?

  • Marco Valerio Mariani,
  • Nicola Pierucci,
  • Sara Trivigno,
  • Pietro Cipollone,
  • Agostino Piro,
  • Cristina Chimenti,
  • Domenico Giovanni Della Rocca,
  • Fabio Miraldi,
  • Carmine Dario Vizza and
  • Carlo Lavalle

3 March 2024

Background: The probability of spontaneous conversion (SCV) to sinus rhythm (SR) in patients presenting to the emergency department (ED) with hemodynamically stable, symptomatic atrial fibrillation (AF) is not well known. Objective: To develop and va...

  • Article
  • Open Access
3 Citations
2,907 Views
18 Pages

2 November 2021

The spontaneous symmetry breaking phenomena applied to Quantum Finance considers that the martingale state in the stock market corresponds to a ground (vacuum) state if we express the financial equations in the Hamiltonian form. The original analysis...

  • Article
  • Open Access
2 Citations
2,306 Views
21 Pages

The Impact of Dynamic Risk Interdependencies on the Saudi Precast Concrete Industry

  • Khalid S. Al-Gahtani,
  • Mohammed I. Aldokhi,
  • Naif M. Alsanabani,
  • Hatim F. Alotaibi and
  • Abdulrahman A. Bin Mahmoud

The precast concrete production process faces uncertainties and risks that reduce the efficiency of the Saudi precast concrete industry. Assessing the risk factors’ interdependence yields better results than considering individual analyses only...

  • Article
  • Open Access
5 Citations
2,116 Views
24 Pages

Quantum State Reduction of General Initial States through Spontaneous Unitarity Violation

  • Aritro Mukherjee,
  • Srinivas Gotur,
  • Jelle Aalberts,
  • Rosa van den Ende,
  • Lotte Mertens and
  • Jasper van Wezel

31 January 2024

The inability of Schrödinger’s unitary time evolution to describe the measurement of a quantum state remains a central foundational problem. It was recently suggested that the unitarity of Schrödinger dynamics can be spontaneously bro...

  • Article
  • Open Access
7 Citations
2,856 Views
17 Pages

Disease-Modifying Therapies (DMTs) in Pregnant and Lactating Women with Multiple Sclerosis: Analysis of Real-World Data from EudraVigilance Database

  • Liberata Sportiello,
  • Raffaella Di Napoli,
  • Nunzia Balzano,
  • Annamaria Mascolo,
  • Rosanna Ruggiero,
  • Luigi Di Costanzo,
  • Davida Monaco,
  • Giorgia Teresa Maniscalco and
  • Annalisa Capuano

6 November 2023

(1) Background: The purpose of study was to compare the safety profile of glatiramer with natalizumab, alemtuzumab and ocrelizumab in pregnant and lactating women affected by multiple sclerosis (MS). (2) Methods: Individual case safety reports (ICSRs...

  • Article
  • Open Access
5 Citations
3,248 Views
19 Pages

14 October 2021

The molecular details of the passive water flux across the hydrophobic membrane interior are still a matter of debate. One of the postulated mechanisms is the spontaneous, water-filled pore opening, which facilitates the hydrophilic connection betwee...

  • Article
  • Open Access
2 Citations
4,340 Views
13 Pages

Ductus arteriosus closure may be delayed in preterm infants, and prostaglandin, a vasodilator, can affect ductal patency. Furosemide can increase renal prostaglandin synthesis, so its net effect on patent ductus arteriosus (PDA) is uncertain. Our goa...

  • Article
  • Open Access
1,457 Views
19 Pages

Cytokine Expression and Haptoglobin Levels in Bovine Fetuses Spontaneously Aborted by Intracellular Infectious Agents and by Probable Infectious Etiology

  • Emiliano Sosa,
  • Natalia Pla,
  • Dadin Prando Moore,
  • Juan Agustín García,
  • Lucía María Campero,
  • María Andrea Fiorentino,
  • Evangelina Miqueo,
  • Erika González Altamiranda,
  • Fermín Lázaro and
  • Karen Morán
  • + 4 authors

1 October 2025

Intracellular pathogens such as Neospora caninum, Brucella abortus, and Bovine Viral Diarrhea Virus (BVDV) are major contributors to bovine abortions, yet many cases remain without a definitive etiological diagnosis despite inflammatory evidence. Thi...

  • Communication
  • Open Access
14 Citations
8,283 Views
10 Pages

4 February 2017

The spontaneous combustion of hydrogen–oxygen mixture observed in nanobubbles at room temperature is a puzzling phenomenon that has no explanation in the standard combustion theory. We suggest that the hydrogen atoms needed to ignite the reaction cou...

  • Article
  • Open Access
1 Citations
859 Views
18 Pages

Spontaneous Mesotheliomas in Germline Bap1 Heterozygous Mice from Different Genetic Backgrounds

  • Yuwaraj Kadariya,
  • Li Zhang,
  • Eleonora Sementino,
  • Eric Ross and
  • Joseph R. Testa

19 August 2025

Background: BAP1 mutation carriers are predisposed to the development of mesothelioma. In mice, there is limited data and controversy about whether germline Bap1 heterozygous mutations alone cause mesothelioma. However, a marked increase in mesotheli...

  • Article
  • Open Access
1 Citations
1,589 Views
10 Pages

26 August 2025

Background/Objectives: Miscarriage (spontaneous abortion) can precipitate post-traumatic stress disorder (PTSD). In Peru, post-loss mental healthcare is limited. We aimed to identify factors associated with PTSD symptoms persisting ≥ 3 months amon...

  • Article
  • Open Access
5 Citations
3,856 Views
15 Pages

Enhanced Astrocyte Activity and Excitatory Synaptic Function in the Hippocampus of Pentylenetetrazole Kindling Model of Epilepsy

  • Franco Díaz,
  • Freddy Aguilar,
  • Mario Wellmann,
  • Andrés Martorell,
  • Camila González-Arancibia,
  • Lorena Chacana-Véliz,
  • Ignacio Negrón-Oyarzo,
  • Andrés E. Chávez,
  • Marco Fuenzalida and
  • Francisco Nualart
  • + 2 authors

25 September 2023

Epilepsy is a chronic condition characterized by recurrent spontaneous seizures. The interaction between astrocytes and neurons has been suggested to play a role in the abnormal neuronal activity observed in epilepsy. However, the exact way astrocyte...

  • Article
  • Open Access
2 Citations
1,897 Views
20 Pages

Whole-Genome Sequencing and Analysis of Tumour-Forming Radish (Raphanus sativus L.) Line

  • Xenia Kuznetsova,
  • Irina Dodueva,
  • Alexey Afonin,
  • Emma Gribchenko,
  • Lavrentii Danilov,
  • Maria Gancheva,
  • Varvara Tvorogova,
  • Nikita Galynin and
  • Lyudmila Lutova

Spontaneous tumour formation in higher plants can occur in the absence of pathogen invasion, depending on the plant genotype. Spontaneous tumour formation on the taproots is consistently observed in certain inbred lines of radish (Raphanus sativus va...

  • Article
  • Open Access
5 Citations
2,417 Views
19 Pages

25 November 2022

The spontaneous combustion of coal gangue dumps after reclamation causes severe harm to the ecological environment surrounding mining areas. Using remote sensing technology to determine vegetation heat stress levels is an important way to evaluate th...

  • Article
  • Open Access
25 Citations
6,657 Views
15 Pages

9 December 2016

An indispensable prerequisite for establishing a scenario of life emerging by natural processes is the requirement that the first simple proto-molecules could have had a realistic probability of self-assembly from random molecular polymers in the pre...

  • Article
  • Open Access
7 Citations
7,023 Views
12 Pages

Vestibular and Oculomotor Findings in Vestibular Migraine Patients

  • Sofia Waissbluth,
  • Valeria Sepúlveda,
  • Jai-Sen Leung and
  • Javier Oyarzún

8 August 2023

Background: Vestibular migraine (VM) is the most frequent etiology of recurrent spontaneous episodic vertigo. Vestibular and oculomotor abnormalities have been described in VM; however, the diagnosis is currently based on symptoms. The objective of t...

  • Communication
  • Open Access
6 Citations
2,607 Views
8 Pages

Natural History and Hepatitis B Virus Surface Antigen (HBsAg) Spontaneous Seroclearance in Hepatitis B Virus e-Antigen (HBeAg)-Negative Patients with Inactive Chronic Infection: A Multicenter Regional Study from South Italy

  • Michele Barone,
  • Andrea Iannone,
  • Martino Mezzapesa,
  • Michele Milella,
  • Francesco Di Gennaro,
  • Grazia Niro,
  • Rosa Cotugno,
  • Raffaele Cozzolongo,
  • Giuseppe Mennea and
  • Maria Rendina
  • + 1 author

26 September 2023

Spontaneous HBsAg seroclearance has been mainly studied in populations from Asia, Australia, the Pacific Islands, and Polynesia. For the first time, we evaluated the spontaneous HBsAg seroclearance and its possible associated factors and the risk of...

  • Review
  • Open Access
50 Citations
6,111 Views
16 Pages

Anti-Epileptogenic Effects of Antiepileptic Drugs

  • Barbara Miziak,
  • Agnieszka Konarzewska,
  • Marzena Ułamek-Kozioł,
  • Monika Dudra-Jastrzębska,
  • Ryszard Pluta and
  • Stanisław J. Czuczwar

Generally, the prevalence of epilepsy does not exceed 0.9% of the population and approximately 70% of epilepsy patients may be adequately controlled with antiepileptic drugs (AEDs). Moreover, status epilepticus (SE) or even a single seizure may produ...

  • Article
  • Open Access
1 Citations
1,243 Views
13 Pages

Spontaneous Resolution of Ventricular Pre-Excitation During Childhood: A Retrospective Study

  • Antonio Sanzo,
  • Alessandro Seganti,
  • Andrea Demarchi,
  • Riccardo Simone Fino,
  • Irene Raso,
  • Alessia Claudia Codazzi,
  • Barbara Petracci,
  • Andrea Bongiorno,
  • Roberto Rordorf and
  • Savina Mannarino

29 March 2025

Background/Objectives: Ventricular pre-excitation (VP) increases the risk of sudden cardiac death among children. While transcatheter ablation could potentially be therapeutic, it is not without risk, especially in smaller children. Accessory pathway...

  • Article
  • Open Access
15 Citations
6,441 Views
14 Pages

29 July 2018

This study deals with the spontaneous spreading of stone bunds in the central Ethiopian highlands, i.e., the adoption and implementation of stone bunds by farmers on their own initiative. The study tests the hypothesis that spontaneously implemented...

  • Article
  • Open Access
12 Citations
3,119 Views
20 Pages

Safety Profile of the Trastuzumab-Based ADCs: Analysis of Real-World Data Registered in EudraVigilance

  • Claudiu Morgovan,
  • Carmen Maximiliana Dobrea,
  • Anca Butuca,
  • Anca Maria Arseniu,
  • Adina Frum,
  • Luca Liviu Rus,
  • Adriana Aurelia Chis,
  • Anca Maria Juncan,
  • Felicia Gabriela Gligor and
  • Cecilia Georgescu
  • + 2 authors

Trastuzumab (T) and tyrosine kinase inhibitors (TKIs) are among the first-line treatments recommended for HER2-positive breast cancer. More recently, antibody-drug conjugates (ADCs) such as trastuzumab deruxtecan (T-DXd) and trastuzumab emtansine (T-...

  • Article
  • Open Access
2 Citations
1,839 Views
14 Pages

Z Boson Emission by a Neutrino in de Sitter Expanding Universe

  • Mihaela-Andreea Băloi,
  • Cosmin Crucean and
  • Diana Dumitrele

19 March 2024

The production of Z bosons in emission processes by neutrinos in the expanding de Sitter universe is studied by using perturbative methods. The total probability and transition rate for the spontaneous emission of a Z boson by a neutrino is computed...

  • Article
  • Open Access
1 Citations
2,037 Views
22 Pages

Cortical neurons integrate upstream signals and random electrical noise to gate signaling outcomes, leading to statistically random patterns of activity. Yet classically, the neuron is modeled as a binary computational unit, encoding Shannon entropy....

  • Review
  • Open Access
46 Citations
12,803 Views
34 Pages

13 December 2012

Post-marketing detection and surveillance of potential safety hazards are crucial tasks in pharmacovigilance. To uncover such safety risks, a wide set of techniques has been developed for spontaneous reporting data and, more recently, for longitudina...

  • Article
  • Open Access
3 Citations
2,774 Views
16 Pages

Emergent Criticality in Coupled Boolean Networks

  • Chris Kang,
  • Madelynn McElroy and
  • Nikolaos K. Voulgarakis

27 January 2023

Early embryonic development involves forming all specialized cells from a fluid-like mass of identical stem cells. The differentiation process consists of a series of symmetry-breaking events, starting from a high-symmetry state (stem cells) to a low...

  • Article
  • Open Access
7 Citations
3,056 Views
15 Pages

Early Blood Analysis and Gas Exchange Monitoring in the Canine Neonate: Effect of Dam’s Size and Birth Order

  • Brenda Reyes-Sotelo,
  • Asahi Ogi,
  • Patricia Mora-Medina,
  • Chiara Mariti,
  • Adriana Olmos-Hernández,
  • Ismael Hernández-Ávalos,
  • Adriana Domínguez-Oliva,
  • Marcelino Evodio Rosas,
  • Antonio Verduzco-Mendoza and
  • Angelo Gazzano

9 June 2022

In canines, size at birth is determined by the dam’s weight, which would probably affect the newborn’s viability due to litter size and birth order. Fetal hypoxia causes distress and acidemia. Identifying physiological blood alterations i...

  • Article
  • Open Access
8 Citations
3,833 Views
12 Pages

Airglow Derived Measurements of Q-Branch Transition Probabilities for Several Hydroxyl Meinel Bands

  • Christoph Franzen,
  • Patrick Joseph Espy,
  • Niklas Hofmann,
  • Robert Edward Hibbins and
  • Anlaug Amanda Djupvik

22 October 2019

Spectroscopic measurements of the hydroxyl (OH) airglow emissions are often used to infer neutral temperatures near the mesopause. Correct Einstein coefficients for the various transitions in the OH airglow are needed to calculate accurate temperatur...

  • Article
  • Open Access
1,949 Views
13 Pages

Temporal Patterns of Air Leak Resolution in Secondary Spontaneous Pneumothorax: A Hazard Function Analysis for Optimal Intervention Timing

  • Ryo Takeyama,
  • Yoshikane Yamauchi,
  • Shinya Kohmaru,
  • Shizuka Morita,
  • Hikaru Takahashi,
  • Tomoki Nishida,
  • Yuichi Saito and
  • Yukinori Sakao

5 June 2025

Objectives: This study was aimed to identify risk factors for persistent air leak after chest tube placement for secondary spontaneous pneumothorax and to determine the optimal timing of treatment. Methods: We retrospectively analyzed 221 cases of se...

  • Review
  • Open Access
2 Citations
1,930 Views
9 Pages

28 February 2025

Graves’ disease and hyperthyroidism in women with childbearing potential are a challenge in pre-conceptional counseling. The non-surgical alternatives are radioiodine therapy or antithyroid drugs. Here, we focus on the TSH receptor antibody (TR...

  • Article
  • Open Access
2 Citations
3,062 Views
12 Pages

A Novel Approach to Parameter Determination of the Continuous Spontaneous Localization Collapse Model

  • Kristian Piscicchia,
  • Alessio Porcelli,
  • Angelo Bassi,
  • Massimiliano Bazzi,
  • Mario Bragadireanu,
  • Michael Cargnelli,
  • Alberto Clozza,
  • Luca De Paolis,
  • Raffaele Del Grande and
  • Maaneli Derakhshani
  • + 16 authors

4 February 2023

Models of dynamical wave function collapse consistently describe the breakdown of the quantum superposition with the growing mass of the system by introducing non-linear and stochastic modifications to the standard Schrödinger dynamics. Among th...

  • Article
  • Open Access
10 Citations
3,341 Views
16 Pages

A Pharmacovigilance Study Regarding the Risk of Antibiotic-Associated Clostridioides difficile Infection Based on Reports from the EudraVigilance Database: Analysis of Some of the Most Used Antibiotics in Intensive Care Units

  • Bogdan Ioan Vintila,
  • Anca Maria Arseniu,
  • Claudiu Morgovan,
  • Anca Butuca,
  • Mihai Sava,
  • Victoria Bîrluțiu,
  • Luca Liviu Rus,
  • Steliana Ghibu,
  • Alina Simona Bereanu and
  • Ioana Roxana Codru
  • + 1 author

9 November 2023

The Gram-positive anaerobic bacterium Clostridioides difficile (CD) can produce intense exotoxins, contributing to nosocomial infections, and it is the most common cause of health-care-associated infectious diarrhea. Based on spontaneous Individual C...

  • Feature Paper
  • Article
  • Open Access
20 Citations
5,368 Views
19 Pages

On the Neutron Transition Magnetic Moment

  • Zurab Berezhiani,
  • Riccardo Biondi,
  • Yuri Kamyshkov and
  • Louis Varriano

13 August 2019

We discuss the possibility of the transition magnetic moments (TMM) between the neutron n and its hypothetical sterile twin “mirror neutron” n′ from a parallel particle “mirror” sector. The neutron can be spontaneously c...

  • Article
  • Open Access
1 Citations
2,683 Views
25 Pages

3 November 2022

Modern cars utilise Advanced Driver Assistance Systems (ADAS) in several ways. In ADAS, the use of multiple sensors to gauge the environment surrounding the ego-vehicle offers numerous advantages, as fusing information from more than one sensor helps...

  • Review
  • Open Access
2 Citations
8,191 Views
25 Pages

The prevalence of cerebral amyloid angiopathy (CAA) has been shown to increase with age, with rates reported to be around 50–60% in individuals over 80 years old who have cognitive impairment. The disease often presents as spontaneous lobar int...

  • Article
  • Open Access
12 Citations
3,619 Views
22 Pages

7 September 2022

Orthotropic steel decks (OSDs) are inevitably subjected to fatigue damage caused by cycled vehicle loads in long-span bridges. This study establishes a probabilistic analysis framework integrating the dynamic Bayesian network (DBN) and fracture mecha...

  • Article
  • Open Access
6 Citations
6,982 Views
12 Pages

Crystal Growth and Spectroscopic Investigations of Tm3+:Li3Ba2Gd3(MoO4)8 Crystal

  • Mingjun Song,
  • Lintong Wang,
  • Nana Zhang,
  • Xishi Tai and
  • Guofu Wang

17 January 2014

Tm3+:Li3Ba2Gd3(MoO4)8 crystal has been grown by the top seeded solution growth (TSSG) method from a Li2MoO4 flux. The room temperature polarized absorption spectra, fluorescence spectra, and fluorescence decay curves of the crystal were measured. B...

  • Article
  • Open Access
4 Citations
2,702 Views
11 Pages

Antihypertensive Effect of Dietary β-Conglycinin in the Spontaneously Hypertensive Rat (SHR)

  • Koji Kawabeta,
  • Masahiro Yuasa,
  • Michihiro Sugano and
  • Kazunori Koba

Dietary β-conglycinin has been shown to increase plasma adiponectin concentration and decrease visceral adipose tissue weight in rats. Since adiponectin is one of the factors regulating blood pressure, as well as modulating lipid metabolism, we...

  • Review
  • Open Access
2 Citations
4,696 Views
17 Pages

Extraction of First Permanent Molars in Children—A Comprehensive Review of History, Aim, Space Closure and Other Consequences

  • Ahmad Al Masri,
  • Mhd Said Mourad,
  • Christian H. Splieth,
  • Karl-Friedrich Krey and
  • Julian Schmoeckel

25 March 2025

Compromised first permanent molars (FPMs) in children pose major challenges for dentists and patients even in low-caries-risk populations. Whether due to caries or Molar Incisor Hypomineralization (MIH), compromised FPMs at an early age require caref...

  • Article
  • Open Access
3 Citations
2,741 Views
12 Pages

28 April 2022

Papaverine is one of the isoquinoline alkaloids derived from opium which is a vasodilator and smooth muscle relaxant. Using its chemical structure as a basic model, we synthesized 2-chloro-N-(1-(3,4-dimethoxyphenyl)propan-2-yl)-2-phenylacetamide as a...

  • Article
  • Open Access
12 Citations
2,960 Views
19 Pages

2 September 2023

The prevention and control of gas explosion accidents are important means to improving the level of coal mine safety, and risk assessment has a positive effect on eliminating the risk of gas explosions. Aiming at the shortcomings of current risk asse...

  • Feature Paper
  • Article
  • Open Access
11 Citations
11,826 Views
14 Pages

Use of Mechanical Chest Compression for Resuscitation in Out-Of-Hospital Cardiac Arrest—Device Matters: A Propensity-Score-Based Match Analysis

  • Roberto Primi,
  • Sara Bendotti,
  • Alessia Currao,
  • Giuseppe Maria Sechi,
  • Gianluca Marconi,
  • Greta Pamploni,
  • Gianluca Panni,
  • Davide Sgotti,
  • Ettore Zorzi and
  • Marco Cazzaniga
  • + 19 authors

30 June 2023

Background. Devices for mechanical cardiopulmonary resuscitation (CPR) are recommended when high quality CPR cannot be provided. Different devices are available, but the literature is poor in direct comparison studies. Our aim was to assess whether t...

  • Article
  • Open Access
10 Citations
3,231 Views
12 Pages

A New Mechanism of Open System Evolution and Its Entropy Using Unitary Transformations in Noncomposite Qudit Systems

  • Julio A. López-Saldívar,
  • Octavio Castaños,
  • Margarita A. Man’ko and
  • Vladimir I. Man’ko

27 July 2019

The evolution of an open system is usually associated with the interaction of the system with an environment. A new method to study the open-type system evolution of a qubit (two-level atom) state is established. This evolution is determined by a uni...

  • Review
  • Open Access
7 Citations
3,188 Views
7 Pages

12 June 2022

Cardioversion (CV) is an essential component of rhythm control strategy in the treatment of atrial fibrillation (AF). Timing of CV is an important manageable factor in optimizing the safety and efficacy of CV. Based on observational studies, the succ...

  • Article
  • Open Access
5 Citations
3,217 Views
14 Pages

Agarwood is known to have a sedative effect and the less studied volatile aromatic constituents it contains may have contribution to the activity. In this study, two Kyara grade (highest-grade agarwood in Japan) samples were extracted using headspace...

  • Article
  • Open Access
5 Citations
4,931 Views
14 Pages

19 February 2019

Using two crystals for spontaneous parametric down-conversion in a parallel setup, we observe two-photon interference with high visibility. The high visibility is consistent with complementarity and the absence of which-path information. The observat...

  • Article
  • Open Access
7 Citations
2,966 Views
11 Pages

Potassium Sulfate: A New Candidate to Explore Non-Photochemical Laser-Induced Nucleation Mechanisms

  • Mélody Briard,
  • Clément Brandel,
  • Sandrine Morin-Grognet,
  • Gérard Coquerel and
  • Valérie Dupray

16 December 2021

In this paper, we report a study on the nucleation behavior of potassium sulfate (K2SO4) from aqueous solutions under the influence of unfocused nanosecond laser pulses. The objective is to contribute to the general understanding of the Non-Photochem...

  • Article
  • Open Access
43 Citations
11,849 Views
12 Pages

The goal of this article is to review work on mind wandering, metacognition and creativity in order to consider their relationship with cognitive flexibility. I introduce a model of the role that mind wandering and metacognition have in the generatio...

  • Review
  • Open Access
1 Citations
7,035 Views
16 Pages

Lazarus Phenomenon or the Return from the Afterlife—What We Know about Auto Resuscitation

  • Piotr Rzeźniczek,
  • Agnieszka Danuta Gaczkowska,
  • Anna Kluzik,
  • Marcin Cybulski,
  • Alicja Bartkowska-Śniatkowska and
  • Małgorzata Grześkowiak

15 July 2023

Autoresuscitation is a phenomenon of the heart during which it can resume its spontaneous activity and generate circulation. It was described for the first time by K. Linko in 1982 as a recovery after discontinued cardiopulmonary resuscitation (CPR)....

  • Article
  • Open Access
4 Citations
3,223 Views
14 Pages

We previously developed a hollow-core photonic crystal fiber (HCPCF) based Raman scattering enhancement technique for gas/human breath analysis. It enhances photon–gas molecule interactions significantly but is still based on CW laser excitatio...

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