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  • Article
  • Open Access
8 Citations
3,385 Views
11 Pages

Underdiagnosis in Background of Emerging Public Health Challenges Related to Peri-Implant Diseases: An Interventional Split-Mouth Study

  • Boris Djuran,
  • Zoran Tatic,
  • Neda Perunovic,
  • Natasa Pejcic and ,
  • Jovana Vukovic,
  • Aleksandra Petkovic-Curcin,
  • Danilo Vojvodic and
  • Mia Rakic
  • + 3 authors+ 0 author

Peri-implant diseases are an emerging public health problem, and it’s considered that limitations of standard diagnostics play the role herein. The study objective was the estimation of pathological bone resorption at clinical and biological le...

(This article belongs to the Special Issue 2nd Edition of Oral Diseases and Public Health)
  • Systematic Review
  • Open Access
11 Citations
6,715 Views
23 Pages

The Effect of Keratinized Mucosa on Peri-Implant Health and Patient-Reported Outcome Measures: A Systematic Review and Meta-Analysis

  • Martina Stefanini,
  • Alberto Pispero,
  • Massimo Del Fabbro,
  • Luca Gobbato and ,
  • Paolo Ghensi,
  • Giovanni Lodi,
  • Anton Sculean,
  • Giovanni Zucchelli and
  • Maria Gabriella Grusovin
  • + 4 authors+ 0 author

26 July 2023

Objectives: The aim of this systematic review was to analyze the effect of keratinized mucosa (KM) on different peri-implant health-related parameters and on patient-reported outcome measures (PROMs). Material and methods: Randomized controlled trial...

(This article belongs to the Section Applied Dentistry and Oral Sciences)
  • Article
  • Open Access
344 Views
13 Pages

14 September 2026

Objectives: We aim to assess the 5-year clinical outcomes of a cylindrical-conical implant system with a progressive thread design and a sandblasted, acid-etched surface and its fixed prostheses under routine clinical conditions. Methods: This retros...

(This article belongs to the Section Dental Implantology)
  • Article
  • Open Access
11 Citations
3,245 Views
12 Pages

16 October 2020

Despite high success rates of dental implants, surface exposure may occur as a consequence of biologic width establishment associated with surgery. This prospective split-mouth study evaluated the effect of early implant surface exposure caused by in...

(This article belongs to the Special Issue Clinical Advances in Implant Dentistry)
  • Article
  • Open Access
20 Citations
4,004 Views
15 Pages

Oral Microcosm Biofilms Grown under Conditions Progressing from Peri-Implant Health, Peri-Implant Mucositis, and Peri-Implantitis

  • Vanessa Sousa,
  • Dave Spratt,
  • Mehmet Davrandi,
  • Nikos Mardas and ,
  • Víctor Beltrán and
  • Nikolaos Donos
  • + 1 author+ 0 author

Peri-implantitis is a disease influenced by dysbiotic microbial communities that play a role in the short- and long-term outcomes of its clinical treatment. The ecological triggers that establish the progression from peri-implant mucositis to peri-im...

(This article belongs to the Special Issue Periodontal and Peri-Implant Diseases)
  • Feature Paper
  • Review
  • Open Access
30 Citations
11,704 Views
21 Pages

The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review

  • Natalia de Campos Kajimoto,
  • Yvonne de Paiva Buischi,
  • Mansour Mohamadzadeh and
  • Peter Loomer

24 September 2024

Peri-implantitis disease has increased significantly over the last years, resulting in increased failure of implants. Many factors may play a role in implant complications and failure, including ones related to the oral microbiota. This literature re...

(This article belongs to the Section Oral Hygiene, Periodontology and Peri-implant Diseases)
  • Article
  • Open Access
24 Citations
4,218 Views
8 Pages

Molecular Biomarkers in Peri-Implant Health and Disease: A Cross-Sectional Pilot Study

  • Alejandra Chaparro,
  • Víctor Beltrán,
  • Daniel Betancur,
  • Ye-Han Sam and ,
  • Haniyeh Moaven,
  • Ali Tarjomani,
  • Nikolaos Donos and
  • Vanessa Sousa
  • + 3 authors+ 0 author

29 August 2022

Background: The aim of this feasibility study was to investigate the concentration level of CCL-20/MIP-3α, BAFF/BLyS, IL-23, RANKL, and Osteoprotegerin in the Peri-Implant Crevicular Fluid (PICF), from patients diagnosed with peri-implant mucos...

(This article belongs to the Special Issue State-of-the-Art Molecular Immunology in Chile)
  • Review
  • Open Access
76 Citations
9,064 Views
21 Pages

Microbiota of Peri-Implant Healthy Tissues, Peri-Implant Mucositis, and Peri-Implantitis: A Comprehensive Review

  • Federica Di Spirito,
  • Francesco Giordano,
  • Maria Pia Di Palo,
  • Francesco D’Ambrosio and ,
  • Bruno Scognamiglio,
  • Giuseppe Sangiovanni,
  • Mario Caggiano and
  • Roberta Gasparro
  • + 3 authors+ 0 author

Understanding the microbiological profiles of peri-implant conditions is crucial for developing effective preventive and therapeutic strategies. This narrative review analyzes the microbial profiles associated with healthy peri-implant sites, peri-im...

(This article belongs to the Section Medical Microbiology)
  • Article
  • Open Access
5 Citations
2,385 Views
14 Pages

Unveiling the Resistome Landscape in Peri-Implant Health and Disease

  • Lucinda J. Bessa,
  • Conceição Egas,
  • João Botelho,
  • Vanessa Machado and ,
  • Gil Alcoforado,
  • José João Mendes and
  • Ricardo Alves
  • + 2 authors+ 0 author

31 January 2025

Background: The human oral microbiome is a critical reservoir for antibiotic resistance; however, subgingival peri-implant biofilms remain underexplored in this context. We aimed to explore the prevalence and distribution of antibiotic resistance gen...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
6 Citations
2,009 Views
15 Pages

3 August 2023

The present pilot study was designed by hypothesizing a possible correlation between lack of accuracy in implant placement and peri-implant hard and soft tissue health. A total of five patients underwent computer-guided implant surgery and full-arch...

(This article belongs to the Special Issue Current Trends and Future Directions in Prosthetic and Implant Dentistry in the Digital Era, 2nd Edition)
  • Article
  • Open Access
9 Citations
2,822 Views
14 Pages

Prevalence of Peri-Implant Disease in Patients with Stage III or IV Periodontitis: Results of a Long-Term Follow-Up from a Specialized Periodontal Practice

  • Pia-Merete Jervøe-Storm,
  • Michael Marder,
  • Martin Hagner,
  • Ina Menn and ,
  • Philipp Menn and
  • Søren Jepsen
  • + 1 author+ 0 author

25 August 2023

The aim of this study was to examine the conditions of implants that had been in function for 5–17 years in stage III/IV periodontitis patients of a specialized periodontal practice. There were 83 patients (43 female/40 male, mean age 64.4 (9.6...

(This article belongs to the Special Issue Implant Dentistry—Trends, Challenges and Innovations)
  • Article
  • Open Access
5 Citations
6,400 Views
34 Pages

3 April 2025

Background/Objectives: The peri-implant soft tissue seal is crucial for the long-term success of subcrestally placed implants (SPIs). However, conventional biologic width—now referred to as supracrestal tissue attachment (STA)—models, ori...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
1 Citations
591 Views
14 Pages

Influence of Obesity on Peri-Implant Health: A Cross-Sectional Clinical and Biochemical Study

  • Mine Keskin,
  • Meltem Zihni Korkmaz,
  • Semih Alperen Bostan and
  • Mehtap Atak

Background: Obesity is associated with alterations in the immune response through increased systemic inflammation. This systemic inflammatory state may increase the risk of peri-implantitis, a condition characterized by infection and tissue destructi...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Article
  • Open Access
3 Citations
2,837 Views
14 Pages

Effect of Abutment Material on aMMP-8 Levels in Peri-Implant Sulcular Fluid over 12 Months: A Randomized Controlled Trial

  • Behrouz Arefnia,
  • Kerstin Theisen,
  • Elisabeth Steyer,
  • Martin Lorenzoni and ,
  • Armin Sokolowski,
  • Ceeneena Ubaidha Maheen,
  • Taina Tervahartiala,
  • Timo Sorsa and
  • Alwin Sokolowski
  • + 4 authors+ 0 author

Background/Objectives: The long-term success of dental implants can be influenced by the material properties of abutments and their interaction with peri-implant tissues. This study investigates the impact of three abutment materials—titanium (...

(This article belongs to the Special Issue Diagnosis and Management of Dental Medicine and Surgery)
  • Review
  • Open Access
58 Citations
10,587 Views
17 Pages

Revisiting Socransky’s Complexes: A Review Suggesting Updated New Bacterial Clusters (GF-MoR Complexes) for Periodontal and Peri-Implant Diseases and Conditions

  • Gustavo Vicentis Oliveira Fernandes,
  • Grace Anne Mosley,
  • William Ross,
  • Ally Dagher and ,
  • Bruno Gomes dos Santos Martins and
  • Juliana Campos Hasse Fernandes
  • + 1 author+ 0 author

This review aimed to identify newly discovered bacteria from individuals with periodontal/peri-implant diseases and organize them into new clusters (GF-MoR complexes) to update Socransky’s complexes (1998). For methodological development, the P...

(This article belongs to the Special Issue Oral Microbes and Human Health)
  • Article
  • Open Access
16 Citations
5,016 Views
10 Pages

Tissue Levels of CD80, CD163 and CD206 and Their Ratios in Periodontal and Peri-Implant Health and Disease

  • Mustafa Yilmaz,
  • Esra Demir,
  • Yigit Firatli,
  • Erhan Firatli and
  • Ulvi Kahraman Gürsoy

10 October 2022

This study aimed to compare tissue levels of CD80 (pro-inflammatory macrophage-related surface marker), CD163, and CD206 (anti-inflammatory macrophage-related surface markers), and their ratios in periodontal and peri-implant health and disease. Alto...

(This article belongs to the Special Issue Advances of Molecular Sciences in Dental Diseases Detection and Treatment)
  • Review
  • Open Access
8 Citations
7,226 Views
12 Pages

Impact of Metformin on Periodontal and Peri-Implant Soft and Hard Tissue

  • Faisal E. Aljofi,
  • Aminah Alesawy,
  • Bader Alzaben,
  • Marwa Alshaikh and ,
  • Norah Alotaibi,
  • Hajer A. Aldulaijan,
  • Sami Alshehri,
  • Eman Aljoghaiman,
  • Yousif A. Al-Dulaijan and
  • Mishali AlSharief
  • + 5 authors+ 0 author

Periodontal and peri-implant soft and hard tissue in diabetic patients have always been a topic of interest for researchers and clinicians alike. Among which, a subtopic that has attracted more attention is the beneficial effect of metformin (MF) on...

(This article belongs to the Section Global Health)
  • Review
  • Open Access
69 Citations
10,949 Views
18 Pages

Surface Coatings of Dental Implants: A Review

  • Angelo Michele Inchingolo,
  • Giuseppina Malcangi,
  • Laura Ferrante,
  • Gaetano Del Vecchio and ,
  • Fabio Viapiano,
  • Alessio Danilo Inchingolo,
  • Antonio Mancini,
  • Ciro Annicchiarico,
  • Francesco Inchingolo and
  • Assunta Patano
  • + 8 authors+ 3 authors

Replacement of missing teeth is possible using biocompatible devices such as endosseous implants. This study aims to analyze and recognize the best characteristics of different implant surfaces that ensure good peri-implant tissue healing and thus cl...

(This article belongs to the Special Issue Advanced Biomaterials and Biotechnology: Applications in Dental Medicine)
  • Systematic Review
  • Open Access
44 Citations
13,423 Views
18 Pages

Smoking Cessation on Periodontal and Peri-Implant Health Status: A Systematic Review

  • Mario Caggiano,
  • Roberta Gasparro,
  • Francesco D’Ambrosio,
  • Massimo Pisano and ,
  • Maria Pia Di Palo and
  • Maria Contaldo
  • + 1 author+ 0 author

31 August 2022

Since smoking is considered among the main risk factors for the onset and progression of periodontitis and peri-implantitis, the present systematic review aimed to evaluate the effect of smoking cessation on clinical, radiographic, and gingival crevi...

(This article belongs to the Special Issue Advances in Periodontal and Peri-Implant Tissues Health Management)
  • Systematic Review
  • Open Access
46 Citations
9,570 Views
35 Pages

Periodontal and Peri-Implant Health Status in Traditional vs. Heat-Not-Burn Tobacco and Electronic Cigarettes Smokers: A Systematic Review

  • Francesco D’Ambrosio,
  • Massimo Pisano,
  • Alessandra Amato,
  • Alfredo Iandolo and ,
  • Mario Caggiano and
  • Stefano Martina
  • + 1 author+ 0 author

8 June 2022

The aim of the present systematic review was to evaluate and possibly differentiate the effects of traditional cigarettes, heat-not-burn tobacco, and electronic cigarettes on periodontal and peri-implant health status. Electronic cigarettes and heat-...

(This article belongs to the Section Oral Hygiene, Periodontology and Peri-implant Diseases)
  • Article
  • Open Access
18 Citations
3,945 Views
16 Pages

Effect Morphology and Surface Treatment of the Abutments of Dental Implants on the Dimension and Health of Peri-Implant Biological Space

  • Ibrahim Dib-Zaitum,
  • Yasmina Guadilla-González,
  • Javier Flores-Fraile,
  • Juan Dib-Zakkour and ,
  • Lorena Benito-Garzón and
  • Javier Montero
  • + 1 author+ 0 author

22 June 2022

Statement of the problem: The gingival configuration around implant abutments is of paramount importance for preserving the underlying marginal bone, and hence for the long-term success of dental implants. Objective: The objective was to study, clini...

  • Article
  • Open Access
16 Citations
5,207 Views
8 Pages

Single tooth implant restorations in the aesthetic area are a demanding challenge. If a complete osseointegration is mandatory, the final result has to result in a higher standard of biomimetic and soft tissue health among natural teeth. This outcome...

(This article belongs to the Special Issue Advanced Functional Biomaterials for Dental Implants)
  • Article
  • Open Access
1 Citations
2,555 Views
12 Pages

Analysis of 8.5 mm Long Dental Implants Provided with Splinted or Solitary Implant Restorations: A 15-Year Prospective Study

  • Jarno Hakkers,
  • Gerdien Telleman,
  • Yvonne C. M. de Waal,
  • Barzi Gareb and ,
  • Arjan Vissink,
  • Gerry M. Raghoebar and
  • Henny J. A. Meijer
  • + 2 authors+ 0 author

30 August 2024

Background/Objectives: The long-term effects of implant properties, such as implant length, platform switch, and crown splinting, on peri-implant health require more investigation. Therefore, the aim was to assess the long-term peri-implant health an...

(This article belongs to the Special Issue Innovative Research in Periodontology and Implantology)
  • Article
  • Open Access
14 Citations
10,361 Views
11 Pages

Association between Peri-Implant Soft Tissue Health and Different Prosthetic Emergence Angles in Esthetic Areas: Digital Evaluation after 3 Years’ Function

  • Diego Lops,
  • Eugenio Romeo,
  • Stefano Calza,
  • Antonino Palazzolo and ,
  • Lorenzo Viviani,
  • Stefano Salgarello,
  • Barbara Buffoli and
  • Magda Mensi
  • + 3 authors+ 0 author

23 October 2022

Background: The aim of the present retrospective study was to assess peri-implant soft tissue health for implants restored with different prosthetic emergence profile angles. Methods: Patients were treated with implants supporting fixed dentures and...

(This article belongs to the Special Issue Current Trends and Future Directions in Prosthetic and Implant Dentistry in the Digital Era)
  • Review
  • Open Access
6 Citations
7,435 Views
15 Pages

Peri-Implant Soft Tissue Augmentation with Connective Tissue Graft Substitutes

  • Ilham Mounssif,
  • Valentina Bentivogli,
  • Alexandra Rendón,
  • Claudio Mazzotti and ,
  • Isabella De Rubertis,
  • Giovanni Zucchelli and
  • Martina Stefanini
  • + 2 authors+ 0 author

18 September 2025

The soft tissue around dental implants plays a crucial role in achieving successful rehabilitation outcomes related to aesthetics, peri-implant health, and bone stability. These tissues, made up of mucosa and keratinized tissue, serve different funct...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Review
  • Open Access
66 Citations
8,576 Views
20 Pages

Probiotics in Periodontal and Peri-Implant Health Management: Biofilm Control, Dysbiosis Reversal, and Host Modulation

  • Massimo Amato,
  • Federica Di Spirito,
  • Francesco D’Ambrosio,
  • Giovanni Boccia and ,
  • Giuseppina Moccia and
  • Francesco De Caro
  • + 1 author+ 0 author

Periodontitis and peri-implantitis are microbially associated diseases of the tissues supporting the teeth and dental implants that are mediated by host inflammation and eventually lead to tooth and dental implant loss. Given the probiotics’ ro...

(This article belongs to the Special Issue Probiotics and the Immune System: The Potential for Postimmunobiotics)
  • Article
  • Open Access
13 Citations
5,476 Views
17 Pages

In fully edentulous patients, the support of a lower dental prosthesis by two implants could improve the chewing ability, retention, and stability of the prosthesis. Despite high success rates of dental implants, complications, such as peri-implantit...

(This article belongs to the Special Issue Osseointegrated Oral implants: Mechanisms of Implant Anchorage, Threats and Long-Term Survival Rates)
  • Article
  • Open Access
6 Citations
2,923 Views
13 Pages

Long-Term Efficacy of Variable-Thread Tapered Implants—A Retrospective, Clinical and Radiological Evaluation

  • Oliver Blume,
  • Eva Maria Schnödt,
  • Michael Back,
  • Jan IR Wildenhof and ,
  • Florian A. Probst and
  • Sven Otto
  • + 1 author+ 0 author

27 October 2020

Background and Objective: There is multifaceted evidence that variable-thread tapered implants (VTTIs) offer high primary stability but few regarding the long-term success. This retrospective clinical and radiological cohort study assessed the long-t...

(This article belongs to the Section Dentistry and Oral Health)
  • Article
  • Open Access
2 Citations
2,646 Views
12 Pages

7-Year Follow-Up of Maxillary Overdentures Supported by Mini-Dental Implants

  • Luc Van Doorne,
  • Laure Demeulenaere,
  • Marie Dejans and
  • Hugo De Bruyn

15 November 2024

Background: Mini dental implants (MDIs) are alternatives to support an overdenture when a standard diameter implant cannot be placed due to lack of bone volume. They reduce the need for invasive bone grafting and lower the barrier for treatment. Aim:...

(This article belongs to the Special Issue Research Progress in Osseointegrated Oral Implants)
  • Article
  • Open Access
43 Citations
8,086 Views
11 Pages

Incidence of Peri-Implantitis and Relationship with Different Conditions: A Retrospective Study

  • Víctor Astolfi,
  • Blanca Ríos-Carrasco,
  • Francisco Javier Gil-Mur,
  • José Vicente Ríos-Santos and ,
  • Beatriz Bullón,
  • Mariano Herrero-Climent and
  • Pedro Bullón
  • + 2 authors+ 0 author

Articles on the prevalence of peri-implant diseases showed that 90% of peri-implant tissues had some form of inflammatory response and a prevalence of peri-implantitis from 28% to 51% according to various publications. Objective: To provide an overvi...

  • Review
  • Open Access
50 Citations
18,768 Views
15 Pages

Current Status of Peri-Implant Diseases: A Clinical Review for Evidence-Based Decision Making

  • Antonio Scarano,
  • Ahmad G. A. Khater,
  • Sergio Alexandre Gehrke,
  • Paola Serra and ,
  • Inchingolo Francesco,
  • Mariastella Di Carmine,
  • Sergio Rexhep Tari,
  • Lucia Leo and
  • Felice Lorusso
  • + 4 authors+ 0 author

Background: the prevalence of peri-implant diseases is constantly growing, particularly with the increasing use of dental implants. As such, achieving healthy peri-implant tissues has become a key challenge in implant dentistry since it considers the...

(This article belongs to the Special Issue Application of Biomaterials and Techniques in Dental Surgical Treatment)
  • Article
  • Open Access
2 Citations
3,930 Views
11 Pages

Difference of Two Antiseptic Gels for the Treatment of Peri-Implant Mucositis on Plaque Index and Bleeding Score: A Randomized Controlled Clinical Study

  • Stefano Storelli,
  • Giulia Palandrani,
  • Barbara Manfredi,
  • Eugenio Romeo and ,
  • Dario De Martis,
  • Claudia Todaro,
  • Ruggero Rodriguez y Baena and
  • Saturnino Marco Lupi
  • + 3 authors+ 0 author

18 January 2023

Aim: To analyze and compare the effectiveness of two antibacterial gels in the treatment of mucositis. Methods: After signing the informed consent, in accordance with the Helsinki Declaration of 1975, revised in 2000, 21 patients were included in the...

(This article belongs to the Special Issue Recent Advances in Biological Science and Technology)
  • Systematic Review
  • Open Access
1 Citations
763 Views
46 Pages

Periodontal and Peri-Implant Status Among Users of Different Inhaled Tobacco and Nicotine Products: A Systematic Review

  • Maria Pia Di Palo,
  • Federica Di Spirito,
  • Francesco Giordano,
  • Giuseppina De Benedetto and ,
  • Roberto Lo Giudice,
  • Federica Piedepalumbo,
  • Gabriele Balsamo,
  • Colomba Pessolano,
  • Marina Garofano and
  • Alessia Bramanti
  • + 6 authors+ 1 author

3 September 2026

Background/Objectives: Periodontal and peri-implant diseases are influenced by several risk factors, including smoking. While cigarette smoking (CS) is a well-established risk factor, the impact of heated tobacco products (HTPs), electronic cigarette...

(This article belongs to the Special Issue Advances in Periodontal and Peri-Implant Tissues Health Management: 2nd Edition)
  • Article
  • Open Access
5 Citations
3,286 Views
9 Pages

Histological and Immunohistochemical Analysis of Peri-Implant Soft and Hard Tissues in Patients with Peri-Implantitis

  • Valentina Flores,
  • Bernardo Venegas,
  • Wendy Donoso,
  • Camilo Ulloa and ,
  • Alejandra Chaparro,
  • Vanessa Sousa and
  • Víctor Beltrán
  • + 2 authors+ 0 author

Currently, researchers are focused on the study of cytokines as predictive biomarkers of peri-implantitis (PI) in order to obtain an early diagnosis and prognosis, and for treatment of the disease. The aim of the study was to characterize the peri-im...

(This article belongs to the Special Issue Periodontal and Peri-Implant Diseases)
  • Review
  • Open Access
64 Citations
15,395 Views
19 Pages

Peri-Implant Diseases: Diagnosis, Clinical, Histological, Microbiological Characteristics and Treatment Strategies. A Narrative Review

  • Ioannis Kormas,
  • Chantal Pedercini,
  • Alessandro Pedercini,
  • Michail Raptopoulos and ,
  • Hatem Alassy and
  • Larry F. Wolff
  • + 1 author+ 0 author

22 November 2020

Since the use of dental implants is continuously increasing, it is imperative for dental practitioners to understand the nature and treatment of peri-implant diseases. The purpose of this manuscript is to comprehensively review peri-implant diseases,...

(This article belongs to the Special Issue Peri-Implant Diseases: Diagnostic Features, Microbiological Characteristics and Novel Surface Decontamination and Treatment Strategies)
  • Review
  • Open Access
23 Citations
5,613 Views
15 Pages

Histologic Evaluation of Soft Tissues around Dental Implant Abutments: A Narrative Review

  • Chiara Cinquini,
  • Vincenzo Marchio,
  • Edouard Di Donna,
  • Fortunato Alfonsi and ,
  • Giacomo Derchi,
  • Marco Nisi and
  • Antonio Barone
  • + 2 authors+ 0 author

27 May 2022

The basis for dental implant success comes not only with the titanium implant osseointegration but also depends on other factors such as the development of a soft tissue barrier, which protects the peri-implant bone from the oral environment. The cha...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
3 Citations
3,508 Views
14 Pages

Epidermal Growth Factor Is Associated with Loss of Mucosae Sealing and Peri-Implant Mucositis: A Pilot Study

  • José Jorge Schoichet,
  • Carlos Fernando de Almeida Barros Mourão,
  • Edgard de Mello Fonseca,
  • Carlos Ramirez and ,
  • Ricardo Villas-Boas,
  • Juliana Prazeres,
  • Valquiria Quinelato,
  • Telma Regina Aguiar,
  • Marina Prado and
  • Priscila Casado
  • + 7 authors+ 2 authors

27 September 2021

This study aimed to evaluate the correlation between epidermal growth factor (EGF) and receptor (EGFR) levels in different clinical stages of dental implant rehabilitation and trace mucositis development’s biological profile. Thirty-six participants...

(This article belongs to the Collection Dentistry, Oral Health and Maxillofacial Surgery)
  • Article
  • Open Access
1,733 Views
15 Pages

Evaluation of the Effectiveness of a Postbiotic in Home Care Maintenance in Patients Affected by Peri-Implant Mucositis

  • Silvia Sabatini,
  • Carlos Perez-Albacete Martinez,
  • Jessica Bassignani,
  • Carolina Maiorani and ,
  • Andrea Butera and
  • Andrea Scribante
  • + 1 author+ 0 author

17 September 2025

Peri-implant mucositis is an inflammatory condition that affects the peri-implant mucosa, without bone involvement. Peri-implant mucositis can include erythema, swelling, and bleeding, and the mucosa can be painful even with the traditional oral hygi...

(This article belongs to the Special Issue State-of-the-Art Peri Implant Therapy)
  • Article
  • Open Access
9 Citations
3,067 Views
9 Pages

Microbiological Profiles of Dental Implants in Metabolic Syndrome Patients: A Case-Control Study

  • Bianca Di Murro,
  • Marta Moretti,
  • Enrico De Smaele,
  • Claudio Letizia and ,
  • Carla Lubrano,
  • Pier Carmine Passarelli,
  • Antonio D’Addona,
  • Giorgio Pompa and
  • Piero Papi
  • + 4 authors+ 0 author

There is a lack of knowledge on the possible influence of systemic conditions on peri-implantitis. The aim of this case-control study is to evaluate the difference in terms of oral pathogens’ concentrations in the peri-implant sulcus of a group of pa...

(This article belongs to the Special Issue Peri-Implant Diseases: Diagnostic Features, Microbiological Characteristics and Novel Surface Decontamination and Treatment Strategies)
  • Review
  • Open Access
49 Citations
11,287 Views
19 Pages

This article focuses on preclinical studies and reviews the available evidence from the literature on dental implant and abutment materials in the last decade. Specifically, different peri-implantitis materials and how surface modifications may affec...

(This article belongs to the Special Issue Feature Papers in Dental Biomaterials)
  • Systematic Review
  • Open Access
4 Citations
2,743 Views
25 Pages

Implant Surface Characteristics and Peri-Implant Outcomes: A Systematic Review of Clinical and Microbiological Evidence

  • Gianna Dipalma,
  • Grazia Marinelli,
  • Paola Bassi,
  • Rosalba Lagioia and ,
  • Antonio Rizzo,
  • Sara Savastano,
  • Francesco Inchingolo,
  • Cristina Grippaudo,
  • Angelo Michele Inchingolo and
  • Alessio Danilo Inchingolo
  • + 5 authors+ 0 author

Background: Implant surface characteristics have been extensively investigated for their potential influence on osseointegration and peri-implant tissue stability. However, their actual clinical relevance in the prevention and progression of peri-imp...

(This article belongs to the Special Issue Advanced Restorative Dental Materials and Implant Technologies)
  • Review
  • Open Access
48 Citations
17,522 Views
17 Pages

The Efficacy of Powered Oscillating Heads vs. Powered Sonic Action Heads Toothbrushes to Maintain Periodontal and Peri-Implant Health: A Narrative Review

  • Camilla Preda,
  • Andrea Butera,
  • Silvia Pelle,
  • Eleonora Pautasso and ,
  • Alessandro Chiesa,
  • Francesca Esposito,
  • Giacomo Oldoini,
  • Andrea Scribante,
  • Anna Maria Genovesi and
  • Saverio Cosola
  • + 5 authors+ 0 author

Objectives: To compare the efficacy of rotating-oscillating heads (ORHs) VS sonic action heads (SAHs) powered toothbrushes on plaque accumulation and gingival inflammation. Methods: An electronic (MEDLINE, Embase, Inspec, PQ SciTech and BIOSIS) and a...

(This article belongs to the Special Issue Advances in Oral Implantology)
  • Article
  • Open Access
3 Citations
3,616 Views
14 Pages

The Trouser Technique: A Novel Approach for Peri-Implant Soft Tissue Augmentation

  • Pablo Pavón,
  • Carla Fons-Badal,
  • Natalia Pérez-Rostoll,
  • Jorge Alonso-Pérez-Barquero and ,
  • María Fernanda Solá-Ruiz and
  • Rubén Agustín-Panadero
  • + 1 author+ 0 author

14 July 2025

Background/Objectives: Peri-implant mucosa plays a key role in both peri-implant health and aesthetics. Differences in contour and color between implants and natural teeth can negatively affect patient satisfaction, while soft tissue deficiency may l...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Conference Report
  • Open Access
11 Citations
5,618 Views
13 Pages

Consensus Report by the Italian Academy of Osseointegration on the Importance of Peri-Implant Soft Tissues

  • Eriberto Bressan,
  • Giovanni Zucchelli,
  • Grazia Tommasato,
  • Paolo Pesce and ,
  • Luigi Canullo,
  • Consensus Meeting Group IAO and
  • Maria Gabriella Grusovin
  • + 2 authors+ 0 author

26 August 2024

Background and Objectives: The influence of the quantity and quality of peri-implant soft tissue on implant health and long-term maintenance is controversial. This consensus aimed to assess the importance of peri-implant soft tissue by analyzing four...

(This article belongs to the Section Dentistry and Oral Health)
  • Case Report
  • Open Access
2 Citations
4,088 Views
9 Pages

Buccal Peri-Implant Soft Tissue Augmentation by Means of a Porcine Collagen Matrix: A Proof of Concept Technical Note

  • Mario Beretta,
  • Carlo Maiorana,
  • Mattia Manfredini,
  • Susanna Ferrario and
  • Pier Paolo Poli

28 December 2020

The quality and quantity of peri-implant soft tissues at the crestal portion of dental implants are important aspects to consider for a long-term successful implant-supported rehabilitation. Some relevant factors attributed to the implant health incl...

(This article belongs to the Special Issue Tissue Regeneration in Dentistry: From Biomaterials to Stem Cell Therapy)
  • Perspective
  • Open Access
6 Citations
4,356 Views
9 Pages

Diagnosis of Biofilm-Associated Peri-Implant Disease Using a Fluorescence-Based Approach

  • Geelsu Hwang,
  • Markus B. Blatz,
  • Mark S. Wolff and
  • Liviu Steier

27 February 2021

Dental implants have become a routine component of daily dental practice and the demand for dental implants is expected to increase significantly in the future. Despite the high success rates of dental implants, failures do occur, resulting in discom...

(This article belongs to the Section Restorative Dentistry and Traumatology)
  • Case Report
  • Open Access
2,809 Views
11 Pages

Using the Modified Apical Access Technique to Treat Peri-Implant Mucosa Defects: Description of the Technique and Three-Dimensional Quantitative Measurement of Buccal Augmented Tissue

  • Norberto Quispe-López,
  • Tiago Marques,
  • Yasmina Guadilla,
  • Javier Flores-Fraile and ,
  • Pablo Garrido-Martínez and
  • Javier Montero
  • + 1 author+ 0 author

24 June 2024

The importance of augmenting the peri-implant soft- and hard-tissue architecture is now widely accepted. However, while most contemporary research supports this premise, clinicians are encountering peri-implant soft tissue defects with increasing fre...

(This article belongs to the Special Issue New Perspectives in Periodontology and Implant Dentistry)
  • Brief Report
  • Open Access
1 Citations
1,008 Views
11 Pages

Horizontal Platelet-Rich Fibrin Membrane Block for Peri-Implant Soft Tissue Augmentation: An Experimental Animal Study with Clinical Illustration

  • Hao Zeng,
  • Yan Wei,
  • Shimin Yu,
  • Xiaoxin Zhang and ,
  • Yun Qiu,
  • Richard J. Miron,
  • Yulan Wang and
  • Yufeng Zhang
  • + 3 authors+ 0 author

4 March 2026

Background/Objectives: Adequate peri-implant soft tissue thickness is essential for long-term peri-implant health and esthetics. Horizontal platelet-rich fibrin (H-PRF) has been proposed to support soft tissue regeneration; however, experimental and...

(This article belongs to the Section Dental Implantology)
  • Article
  • Open Access
3 Citations
1,416 Views
11 Pages

Effect of Leukocyte- and Platelet-Rich Fibrin on Peri-Implant Mucosal Thickness in Edentulous Patients Treated with Mandibular Implant-Retained Overdentures: A Randomized Controlled Trial

  • Ximena Moreno,
  • Patricio Neira,
  • Franz J. Strauss,
  • María Ignacia Mery and ,
  • Reinhard Gruber and
  • Franco Cavalla
  • + 1 author+ 0 author

29 September 2025

Background/Objectives: The maintenance of peri-implant soft tissue health is critical for the long-term success of implant therapy, particularly in edentulous patients rehabilitated with mandibular overdentures. Leukocyte- and platelet-rich fibrin (L...

(This article belongs to the Special Issue Advances in Periodontitis and Other Periodontal Diseases)

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