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Advances in Periodontitis and Other Periodontal Diseases

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 629

Special Issue Editor


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Guest Editor
Unit of Prosthodontics, Department of Innovative Technologies in Medicine and Dentistry, University “G. d’Annunzio” of Chieti-Pescara, 66100 Chieti, Italy
Interests: dentistry; oral surgery; periodontology; ozone therapy; periodontal treatment

Special Issue Information

Dear Colleagues,

For decades, periodontitis has been considered a local inflammatory disease of the periodontal tissues in the oral cavity. Initially, associations of periodontitis with a multitude of noncommunicable diseases were each studied separately, and subsequently, relationships were shown. The associations of periodontitis with morbidities, such as cardiovascular diseases, rheumatoid arthritis, diabetes mellitus, and respiratory diseases, have been demonstrated. As most such studies were cross-sectional in nature, questions about causality cannot be univocally answered. Also, periodontitis as an independent risk factor for one systemic disease becomes even more difficult to assess, since recently periodontitis has also been associated with multimorbidity. Periodontitis and many systemic diseases share environmental, lifestyle, and genetic risk factors, and share immunopathology. The purpose of this Special Issue is to highlight recent findings on periodontal disease and new correlations with systemic diseases.

Dr. Giovanna Murmura
Guest Editor

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Keywords

  • periodontal diseases
  • gingivitis
  • periodontitis
  • systemic disease
  • classification

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Published Papers (1 paper)

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Research

13 pages, 2221 KiB  
Article
Association Between Tobacco and Periodontal Disease in Latin America from 2000 to 2024: Cross-Sectional Analysis of Global Burden of Disease Study
by Brenda Herrera-Serna, Olga López-Soto, Héctor Fuentes-Barría, Raúl Aguilera-Eguía, Lissé Angarita-Davila and Diana Rojas-Gómez
J. Clin. Med. 2025, 14(10), 3549; https://doi.org/10.3390/jcm14103549 - 19 May 2025
Viewed by 534
Abstract
Objectives: This study aims to examine the ecological-level association between active and passive tobacco use and periodontal disease in Latin America from 2000 to 2024. Methods: A cross-sectional ecological study was conducted using secondary data from the Global Burden of Disease Study. Data [...] Read more.
Objectives: This study aims to examine the ecological-level association between active and passive tobacco use and periodontal disease in Latin America from 2000 to 2024. Methods: A cross-sectional ecological study was conducted using secondary data from the Global Burden of Disease Study. Data from 20 Latin American countries were analyzed, stratified by country, sex, and age group. Multiple regression models were used to assess the relationship between tobacco consumption and periodontal disease prevalence, adjusted for age and sex. Results: The prevalence of periodontal disease was high in both sexes, particularly among individuals older than 55 years. The countries with the highest age-standardized rates were Colombia, Panama, and Costa Rica, with nearly 35,000 cases per 100,000 population. Regression models indicated that passive tobacco exposure explained 90.4% of the variability in women (R2 = 0.9041) and 92.5% in men (R2 = 0.9253). Active tobacco use showed weaker associations, with R2 values of 0.3721 in women and 0.4601 in men. Passive exposure demonstrated better predictive accuracy, with lower Root MSE values (3192.8 and 3261.7). Conclusions: There is a significant ecological-level association between tobacco use and periodontal disease in Latin America, particularly for passive exposure. These findings highlight the need to strengthen tobacco control policies and preventive strategies targeting environmental exposure. However, due to the ecological nature of the study, these associations do not imply causality at the individual level. Longitudinal studies with individual-level data are needed to explore the underlying biological and contextual factors. Full article
(This article belongs to the Special Issue Advances in Periodontitis and Other Periodontal Diseases)
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