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Bioengineering
Special Issues
Advanced Restorative Dental Materials and Implant Technologies
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Advanced Restorative Dental Materials and Implant Technologies

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 3193

Special Issue Editors

Dr. Elena-Raluca Baciu

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Guest Editor
Department of Implantology, Removable Dentures, Dental Technology, Faculty of Dental Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universității Street, 700115 Iași, Romania
Interests: dental alloys and polymers; properties of dental materials; innovations in biomaterials for restorative and prosthetic dentistry; additive manufacturing for custom dental solutions; virtual treatment planning
Special Issues, Collections and Topics in MDPI journals
Dr. Alice Mirela Murariu

E-Mail Website
Guest Editor
Department of Surgicals, Faculty of Dental Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universității Street, 700115 Iași, Romania
Interests: dental
Dr. Gabriela Luminița Gelețu

E-Mail Website
Guest Editor
Department of Surgicals, Faculty of Dental Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania
Interests: dental implantology; oral surgery; advanced surgical techniques; ethics and decision-making in oncology; biomarkers for oral carcinoma diagnosis and prognosis; surgical management of oral and maxillof; custom made cranio-maxillofacial implants

Special Issue Information

Dear Colleagues,

Advancements in dental materials and technologies have revolutionized modern dentistry, providing improved solutions for complex dental conditions such as dental caries, periodontal diseases, and tooth loss. These innovations feature advanced materials and state-of-the-art techniques that enhance durability, biocompatibility, and aesthetics, along with custom-made implant technologies designed to ensure superior integration and long-term stability. This Special Issue aims to highlight the latest developments and applications of restorative dental materials and implant technologies in clinical and research contexts.

Researchers and practitioners from the fields of dental materials, restorative dentistry, prosthodontics, periodontics, and oral and orthognathic surgery are encouraged to contribute original research, clinical case studies, reviews, and meta-analyses that explore these advancements and their impact on improving patient care and oral health outcomes.

Dr. Elena-Raluca Baciu
Dr. Alice Mirela Murariu
Dr. Gabriela Luminița Gelețu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • restorative dentistry
  • dental implants
  • patient specific implants
  • nanotechnology
  • guided tissue regeneration
  • digital dentistry
  • minimally invasive techniques
  • 3D printing

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Published Papers (3 papers)

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Research

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11 pages, 1149 KB  
Article
Time- and Cost-Efficient, Minimally Invasive Comparative Assessment of Implant Stability: Reliability and Inter-Examiner Agreement of IST Versus ISQ Across Different Bone Quality Models
by Sung-Joon Kim and Se Hoon Kahm
Bioengineering 2026, 13(1), 86; https://doi.org/10.3390/bioengineering13010086 - 12 Jan 2026
Viewed by 572
Abstract
This study evaluated the reliability and inter-examiner agreement of the Implant Stability Test (IST) by Anycheck compared to the established Implant Stability Quotient (ISQ) by Osstell across different bone quality types. Seven dental hygienists with varying experience levels performed stability measurements using both [...] Read more.
This study evaluated the reliability and inter-examiner agreement of the Implant Stability Test (IST) by Anycheck compared to the established Implant Stability Quotient (ISQ) by Osstell across different bone quality types. Seven dental hygienists with varying experience levels performed stability measurements using both devices on standardized implant models representing hard, normal, and soft bone qualities. Both IST and ISQ demonstrated excellent inter-examiner reliability (ICC > 0.90) across all bone quality types, with strong positive correlations (r > 0.85) between measurements regardless of bone density. No significant differences were found in measurement consistency between examiners with different experience levels for either device. The results demonstrate that IST provides comparable reliability to ISQ for implant stability assessment, with excellent inter-examiner agreement and accessibility for practitioners with varying experience levels. The IST system offers practical advantages including elimination of SmartPeg requirements, reduced abutment manipulation, and simplified measurement protocols, supporting its potential as a reliable and cost-effective alternative to traditional ISQ measurements under standardized experimental conditions. Full article
(This article belongs to the Special Issue Advanced Restorative Dental Materials and Implant Technologies)
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13 pages, 1300 KB  
Article
Can Preoperative Blood Inflammatory Biomarkers Predict Early Dental Implant Outcomes in Systemically Healthy Patients?
by Elena-Raluca Baciu, Cezara Andreea Onică, Gabriela Luminița Gelețu, Neculai Onică, Bogdan Florin Toma, Alexandra Cornelia Teodorescu, Costin Iulian Lupu and Alice Murariu
Bioengineering 2025, 12(11), 1208; https://doi.org/10.3390/bioengineering12111208 - 5 Nov 2025
Viewed by 1199
Abstract
The aim of this study was to assess whether baseline the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), the systemic immune-inflammation index (SII), and C-reactive protein (CRP) could predict postoperative outcomes in systemically healthy patients receiving dental implants. A retrospective analysis of 116 [...] Read more.
The aim of this study was to assess whether baseline the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), the systemic immune-inflammation index (SII), and C-reactive protein (CRP) could predict postoperative outcomes in systemically healthy patients receiving dental implants. A retrospective analysis of 116 systemically healthy adults receiving dental implants was conducted. To minimise confounding, individuals over 50 years old, smokers, and those with systemic diseases, stage III/IV periodontitis, or current medication use were excluded. Periodontal status was classified as clinically healthy or stable. Baseline CRP and complete blood count-derived indices (NLR, PLR, SII) were recorded preoperatively. The primary outcome was osseointegration (proper versus impaired). Implant success was 95.7% (n = 111), with early implant failure occurring in 4.3% (n = 5). Females exhibited higher PLR values than males (p = 0.041), and SII was higher in periodontally stable patients compared to clinically healthy ones (p = 0.036). In systemically healthy patients, routine preoperative screening based on NLR, PLR, and CRP did not improve prediction of early implant failure, whereas SII demonstrated good, statistically significant discrimination (p = 0.015). These findings emphasise the need for further research to clarify the predictive value of blood inflammatory biomarkers. Full article
(This article belongs to the Special Issue Advanced Restorative Dental Materials and Implant Technologies)
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Other

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25 pages, 1077 KB  
Systematic Review
Implant Surface Characteristics and Peri-Implant Outcomes: A Systematic Review of Clinical and Microbiological Evidence
by Gianna Dipalma, Grazia Marinelli, Paola Bassi, Rosalba Lagioia, Antonio Rizzo, Sara Savastano, Francesco Inchingolo, Cristina Grippaudo, Angelo Michele Inchingolo and Alessio Danilo Inchingolo
Bioengineering 2026, 13(3), 299; https://doi.org/10.3390/bioengineering13030299 - 3 Mar 2026
Cited by 1 | Viewed by 744
Abstract
Background: Implant surface characteristics have been extensively investigated for their potential influence on osseointegration and peri-implant tissue stability. However, their actual clinical relevance in the prevention and progression of peri-implant diseases remains controversial. This systematic review aimed to synthesize the available clinical and [...] Read more.
Background: Implant surface characteristics have been extensively investigated for their potential influence on osseointegration and peri-implant tissue stability. However, their actual clinical relevance in the prevention and progression of peri-implant diseases remains controversial. This systematic review aimed to synthesize the available clinical and microbiological evidence on the impact of different implant surface characteristics and surface modifications on peri-implant outcomes. Materials and Methods: Conducted according to PRISMA and registered in PROSPERO, an electronic search of PubMed, Scopus, and Web of Science (2015–2025) identified clinical studies assessing associations between implant surface characteristics/modifications and peri-implant clinical, radiographic, microbiological, or biomolecular outcomes. Risk of bias was evaluated using ROBINS-I. Results: Thirteen studies (randomized, controlled, and cohort designs) were included. Most trials reported minimal differences in marginal bone loss and peri-implant parameters across surfaces. Potential advantages were mainly observed during early healing or in compromised bone. Long-term evidence emphasized the predominance of patient- and site-related risk factors. Microbiological outcomes were scarce and heterogeneous. Conclusions: Implant surface modifications appear to exert a limited and context-dependent influence on peri-implant outcomes. Long-term peri-implant health is primarily driven by multifactorial interactions involving host, microbial, and clinical factors rather than surface characteristics alone. Full article
(This article belongs to the Special Issue Advanced Restorative Dental Materials and Implant Technologies)
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