Effect of Leukocyte- and Platelet-Rich Fibrin on Peri-Implant Mucosal Thickness in Edentulous Patients Treated with Mandibular Implant-Retained Overdentures: A Randomized Controlled Trial
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Screening and Consenting
2.3. Outcome Measures
2.4. Surgical Protocol
2.5. Statistical Analysis
3. Results
4. Discussion
5. Limitations
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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| L-PRF | Control | p-Value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| T0 | T2 | T3 | T0 | T2 | T3 | T0 | T2 | T3 | |
| PD (mm) | 1.6 (±0.5) | 1.4 (±0.5) | 1.8 (±0.6) | 1.4 (±0.5) | 0.60 | 0.46 | |||
| KTW (mm) | 2.7 (±1.6) | 2.5 (±1.8) | 2.4 (±0.9) | 2.5 (±1.8) | 2.4 (±0.9) | 2.7 (±0.9) | 0.53 | 0.68 | 0.79 |
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Moreno, X.; Neira, P.; Strauss, F.J.; Mery, M.I.; Gruber, R.; Cavalla, F. Effect of Leukocyte- and Platelet-Rich Fibrin on Peri-Implant Mucosal Thickness in Edentulous Patients Treated with Mandibular Implant-Retained Overdentures: A Randomized Controlled Trial. J. Clin. Med. 2025, 14, 6917. https://doi.org/10.3390/jcm14196917
Moreno X, Neira P, Strauss FJ, Mery MI, Gruber R, Cavalla F. Effect of Leukocyte- and Platelet-Rich Fibrin on Peri-Implant Mucosal Thickness in Edentulous Patients Treated with Mandibular Implant-Retained Overdentures: A Randomized Controlled Trial. Journal of Clinical Medicine. 2025; 14(19):6917. https://doi.org/10.3390/jcm14196917
Chicago/Turabian StyleMoreno, Ximena, Patricio Neira, Franz J. Strauss, María Ignacia Mery, Reinhard Gruber, and Franco Cavalla. 2025. "Effect of Leukocyte- and Platelet-Rich Fibrin on Peri-Implant Mucosal Thickness in Edentulous Patients Treated with Mandibular Implant-Retained Overdentures: A Randomized Controlled Trial" Journal of Clinical Medicine 14, no. 19: 6917. https://doi.org/10.3390/jcm14196917
APA StyleMoreno, X., Neira, P., Strauss, F. J., Mery, M. I., Gruber, R., & Cavalla, F. (2025). Effect of Leukocyte- and Platelet-Rich Fibrin on Peri-Implant Mucosal Thickness in Edentulous Patients Treated with Mandibular Implant-Retained Overdentures: A Randomized Controlled Trial. Journal of Clinical Medicine, 14(19), 6917. https://doi.org/10.3390/jcm14196917

