You are currently viewing a new version of our website. To view the old version click .

351 Results Found

  • Review
  • Open Access
24 Citations
9,516 Views
35 Pages

Open-Source 3D Printing in the Prosthetic Field—The Case of Upper Limb Prostheses: A Review

  • Kevin Wendo,
  • Olivier Barbier,
  • Xavier Bollen,
  • Thomas Schubert,
  • Thierry Lejeune,
  • Benoit Raucent and
  • Raphael Olszewski

Upper limb loss alters individuals’ private and professional life. Prosthetic devices are thus a solution to supply the missing upper limb segments. Nevertheless, commercial prostheses are often unaffordable, or inaccessible, to underprivileged...

  • Technical Note
  • Open Access
1,644 Views
7 Pages

Background: Patients with no-option chronic limb-threatening ischemia (NoCLTI), lacking suitable distal arteries for conventional revascularization, face major limb amputation. The 1-year mortality rate after major amputation is 48.3%, increasing to...

  • Article
  • Open Access
1,157 Views
13 Pages

Skill-Level Dependent Lower Limb Muscle Synergy Patterns During Open-Stance Forehand Strokes in Competitive Tennis Players

  • Yucheng Wang,
  • Dong Sun,
  • Dongxu Wang,
  • Diwei Chen,
  • Fengping Li,
  • Zhanyi Zhou,
  • Xuanzhen Cen,
  • Yang Song,
  • Danica Janicijevic and
  • Yaodong Gu

27 April 2025

Background: The open-stance forehand is a fundamental technique in tennis, playing a crucial role in competitive performance. Its execution depends heavily on lower limb coordination and neuromuscular control. Athletes of different skill levels often...

  • Article
  • Open Access
1 Citations
3,273 Views
19 Pages

Open On-Limb Robot Locomotion Mechanism with Spherical Rollers and Diameter Adaptation

  • Luz M. Tobar-Subía-Contento,
  • Anthony Mandow and
  • Jesús M. Gómez-de-Gabriel

The rapid development of wearable technologies is increasing research interest in on-body robotics, where relocatable robots can serve as haptic interfaces, support healthcare measurements, or assist with daily activities. However, on-body mobile rob...

  • Article
  • Open Access
6 Citations
3,883 Views
7 Pages

Bacterial Epidemiology of Surgical Site Infections after Open Fractures of the Lower Limb: A Retrospective Cohort Study

  • Tracie Joyner Youbong,
  • Astrid De Pontfarcy,
  • Maxence Rouyer,
  • Alessio Strazzula,
  • Catherine Chakvetadze,
  • Clara Flateau,
  • Samir Sayegh,
  • Coralie Noel,
  • Aurélia Pitsch and
  • Abdelmalek Abbadi
  • + 1 author

10 December 2021

Open lower limb fractures are common injuries, and the occurrence of infectious complications after open fractures is a usual problem. The rate of surgical site infections (SSIs) and the nature and resistance of the germs responsible for SSIs remain...

  • Article
  • Open Access
20 Citations
3,988 Views
17 Pages

8 November 2022

The muscle synergy approach is used to evaluate motor control and to quantitatively determine the number and structure of the modules underlying movement. In experimental studies regarding the upper limb, typically 8 to 16 EMG probes are used dependi...

  • Article
  • Open Access
2,883 Views
43 Pages

Upper-Limb Robotic Exoskeleton for Early Cardiac Rehabilitation Following an Open-Heart Surgery—Mathematical Modelling and Empirical Validation

  • Bogdan Mocan,
  • Claudiu Schonstein,
  • Mircea Murar,
  • Calin Neamtu,
  • Mircea Fulea,
  • Mihaela Mocan,
  • Simona Dragan and
  • Horea Feier

25 March 2023

Robotic exoskeletons have the potential to enhance the quality of life of patients undergoing cardiac rehabilitation. Recent studies found that the use of such devices was associated with significant improvements in physical function, mobility, and o...

  • Article
  • Open Access
5 Citations
3,608 Views
30 Pages

CardioVR-ReTone—Robotic Exoskeleton for Upper Limb Rehabilitation following Open Heart Surgery: Design, Modelling, and Control

  • Bogdan Mocan,
  • Claudiu Schonstein,
  • Calin Neamtu,
  • Mircea Murar,
  • Mircea Fulea,
  • Radu Comes and
  • Mihaela Mocan

5 January 2022

Following cardiac surgery, patients experience difficulties with the rehabilitation process, often finding it difficult, and therefore lack the motivation for rehabilitation activities. As the number of people aged 65 and over will rise by 207 percen...

  • Article
  • Open Access
10 Citations
5,273 Views
12 Pages

18 February 2020

In many countries, 400 units (U) is the maximum dose of onabotulinumtoxinA available to treat upper limb spasticity, but few studies have demonstrated the optimal use of this dose. In the double-blind phase of this randomized, controlled trial, we co...

  • Article
  • Open Access
1,022 Views
14 Pages

16 October 2025

Background/Objectives: Despite their low incidence, popliteal artery aneurysms (PAAs) are the most common aneurysms of the peripheral arteries and carry a high risk of limb loss. The optimal treatment, either with open (OR) or endovascular repai...

  • Article
  • Open Access
2 Citations
2,299 Views
28 Pages

Biomechanical Effects of Lower Limb Asymmetry During Running: An OpenSim Computational Study

  • Andreea Maria Mănescu,
  • Carmen Grigoroiu,
  • Neluța Smîdu,
  • Corina Claudia Dinciu,
  • Iulius Radulian Mărgărit,
  • Adrian Iacobini and
  • Dan Cristian Mănescu

18 August 2025

Symmetry and asymmetry significantly influence running biomechanics, performance, and injury risk. Given the practical, ethical, and methodological constraints inherent in human-subject studies, computational modeling emerges as a valuable alternativ...

  • Article
  • Open Access
2 Citations
1,129 Views
7 Pages

8 April 2009

Objective. Based on recent literature data, subintimal arterial angioplasty, its indications and contraindications, methods and techniques, treatment results, and perspectives are introduced in this article. During the last two decades, with increasi...

  • Article
  • Open Access
2 Citations
2,413 Views
10 Pages

High-Grade Limbs Open Fractures: Time to Find Milestones in the Emergency Setting

  • Michele Altomare,
  • Stefano Granieri,
  • Stefano Piero Bernardo Cioffi,
  • Andrea Spota,
  • Silvia Azisa Basilicò,
  • Osvaldo Chiara and
  • Stefania Cimbanassi

12 November 2021

(1) Background: The Gustilo–Anderson (G/A) grading system is a universally accepted tool used to classify high-grade limb open fractures. The purpose of this study is to find early independent predictors of amputation in emergency settings. (2) Metho...

  • Article
  • Open Access
48 Citations
7,958 Views
20 Pages

18 April 2019

Surface Electromyography (sEMG) signal processing has a disruptive technology potential to enable a natural human interface with artificial limbs and assistive devices. However, this biosignal real-time control interface still presents several restri...

  • Article
  • Open Access
1 Citations
1,848 Views
23 Pages

4 September 2022

To investigate the axial compressive behavior of an opening cold-formed thin-wall C-steel combined double-limb column, C-steel combined I-section columns were modeled in this paper, and the models were validated by experiments on axial-compressed com...

  • Article
  • Open Access
483 Views
16 Pages

11 October 2025

This study aims to investigate the characteristics of load changes in the hip, knee, and ankle joints of the dominant and non-dominant lower limbs of young male runners after long-distance running. Using the OpenSim public dataset (containing bilater...

  • Systematic Review
  • Open Access
13 Citations
5,505 Views
16 Pages

The Effect of Delayed Surgical Debridement in the Management of Open Tibial Fractures: A Systematic Review and Meta-Analysis

  • Marios Nicolaides,
  • Alexandros Vris,
  • Nima Heidari,
  • Peter Bates and
  • Georgios Pafitanis

Introduction: Open tibial fractures are complex injuries with variable outcomes that significantly impact patients’ lives. Surgical debridement is paramount in preventing detrimental complications such as infection and non-union; however, the exact t...

  • Systematic Review
  • Open Access
1 Citations
1,946 Views
18 Pages

Treatment Strategies and Prognostic Outcomes in Acute Limb Ischemia: A Systematic Review and Meta-Analysis Comparing Thrombolytic Therapy and Open Surgical Interventions

  • Mircea Cătălin Coșarcă,
  • Nicolae Alexandru Lazăr,
  • Suzana Vasilica Șincaru,
  • Bogdan Corneliu Bandici,
  • Eduard Costin Argatu,
  • Cosmin Carașca,
  • Ráduly Gergő,
  • Dorin Constantin Dorobanțu,
  • Cristian Trâmbițaș and
  • Adrian Vasile Mureșan

30 April 2025

Background and Objectives: Acute limb ischemia (ALI) is a life-threatening vascular emergency that requires immediate intervention to restore perfusion and prevent limb loss or mortality. Management strategies primarily include thrombolysis and surgi...

  • Review
  • Open Access
822 Views
19 Pages

Fracture-Related Infections: Current Status and Perspectives from the International Society of Antimicrobial Chemotherapy

  • Julie Lourtet-Hascoët,
  • Eric Bonnet,
  • Anna Maria Spera,
  • Tiziana Ascione,
  • Monica Chan,
  • Silvano Esposito,
  • Pasquale Pagliano,
  • Antonia Scobie,
  • Serhat Ünal and
  • Gérard Giordano
  • + 1 author

1 November 2025

Fracture-related infections (FRIs) represent a significant complication in orthopedic trauma care, often leading to delayed bone healing, prolonged hospital stays, and increased patient morbidity. Pathogenesis involves microbial contamination during...

  • Article
  • Open Access
12 Citations
2,963 Views
11 Pages

The Impact of Chronic Kidney Disease on Mid-Term Outcomes after Revascularisation of Peripheral Arterial Occlusive Disease: Results from a Prospective Cohort Study

  • Artur Kotov,
  • Deven A. Blasche,
  • Frederik Peters,
  • Philip Pospiech,
  • Ulrich Rother,
  • Konstantinos Stavroulakis,
  • Jürgen Remig,
  • Christian Schmidt-Lauber,
  • Thomas Zeller and
  • Hartmut Görtz
  • + 2 authors

14 August 2022

Objective: The current study aimed to determine the relationship between chronic kidney disease (CKD) and major 12-month outcomes for patients with in-hospital treatment for symptomatic peripheral arterial occlusive disease (PAOD). Methods: An analys...

  • Article
  • Open Access
18 Citations
7,028 Views
15 Pages

Effect of Heel Lift Insoles on Lower Extremity Muscle Activation and Joint Work during Barbell Squats

  • Zhenghui Lu,
  • Xin Li,
  • Rongrong Xuan,
  • Yang Song,
  • István Bíró,
  • Minjun Liang and
  • Yaodong Gu

The effect of heel elevation on the barbell squat remains controversial, and further exploration of muscle activity might help find additional evidence. Therefore, 20 healthy adult participants (10 males and 10 females) were recruited for this study...

  • Article
  • Open Access
4 Citations
1,618 Views
10 Pages

Long-Term Outcome of Lower Extremity Bypass Surgery in Diabetic and Non-Diabetic Patients with Critical Limb-Threatening Ischaemia in Germany

  • Johanna Surmann,
  • Philipp Meyer,
  • Jasmin Epple,
  • Thomas Schmitz-Rixen,
  • Dittmar Böckler and
  • Reinhart T. Grundmann

Aim: To present the short- and long-term outcomes of lower extremity bypass (LEB) surgery in patients with critical limb-threatening ischaemia (CLTI), comparing diabetic (DM) and non-diabetic (non-DM) patients. Methods: Retrospective analysis of anon...

  • Systematic Review
  • Open Access
1,596 Views
16 Pages

25 September 2024

Background: Compound fractures of the distal tibia (with or without the middle third) represent a challenge for orthopedic and plastic surgeons because of the scarcity of available soft tissue reconstruction and the important comminution of the fract...

  • Article
  • Open Access
1 Citations
3,396 Views
17 Pages

19 July 2024

Stroke causes disability and significantly affects patient quality of life. Post-stroke rehabilitation of upper limb function is crucial, as it affects daily activities and individual autonomy. Traditional rehabilitation methods often require frequen...

  • Article
  • Open Access
12 Citations
2,478 Views
10 Pages

An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate

  • Sorin Barac,
  • Roxana Ramona Onofrei,
  • Petru Vlad Neagoe,
  • Alexandra Ioana Popescu,
  • Stelian Pantea and
  • Andreea Luciana Rață

29 October 2021

An observational study on 22 patients presenting with acute limb ischemia and SARS-CoV-2 infection, and without any other embolic risk factors, was performed. All patients were classified according to Rutherford classification for acute limb ischemia...

  • Article
  • Open Access
3 Citations
1,982 Views
16 Pages

10 February 2024

Background: Glucocorticoids induce osteoporosis, while bisphosphonates treat it, yet both can lead to atypical femoral fractures. Patients on both agents may face challenges in healing from such fractures due to their pathophysiology and pharmacologi...

  • Case Report
  • Open Access
2 Citations
6,405 Views
10 Pages

9 November 2021

Open traumatic lesion of the popliteal artery is relatively rare. Ischemia time longer than 6 h and severity of limb ischemia have been shown to be associated with an increased risk of limb loss. Severe local infection is critical in the presence of...

  • Article
  • Open Access
1 Citations
2,455 Views
10 Pages

Single-Leg Balance and Lower Limb Strength: Quantitative Analysis with the Balance Master System

  • José Manuel Delfa-de-la-Morena,
  • Pedro Pinheiro Paes,
  • Débora Priscila Lima de Oliveira,
  • Frederico Camarotti Júnior,
  • Bruna Daniele Monteiro Lima,
  • Miriam García-González,
  • Juan-José Mijarra-Murillo and
  • Víctor Riquelme-Aguado

Objective: This study investigates the relationship between lower limb strength and postural stability in single-leg stance using the Balance Master system. Methods: The research involved 64 participants divided into sedentary and physically active g...

  • Article
  • Open Access
8 Citations
2,674 Views
13 Pages

Radiofrequency Thermal Ablation for the Treatment of Chronic Insufficiency of the Saphenous Vein—A Comparative Retrospective Study

  • Octavian Andercou,
  • Bogdan Stancu,
  • Horațiu Flaviu Coman,
  • Beatrix Cucuruz,
  • Thomas Noppeney and
  • Dorin Marian

Objectives: The broad spectrum of chronic venous disease encompasses varicose veins, edema, hyperpigmentation and venous ulcers. Radiofrequency thermal ablation is indicated for the treatment of superficial venous reflux of the lower limb. Our resear...

  • Article
  • Open Access
1,732 Views
12 Pages

Reliability Study of Weight-Bearing Upper Extremity Sway Test Performed on a Force Plate in the One-Handed Plank Position

  • Łukasz Oleksy,
  • Anna Mika,
  • Maciej Kuchciak,
  • Grzegorz Bril,
  • Martyna Sopa,
  • Artur Stolarczyk,
  • Olga Adamska,
  • Renata Kielnar,
  • Joanna Zyznawska and
  • Zofia Dzięcioł-Anikiej
  • + 2 authors

20 December 2024

(1) Background: The aim of this study is to determine the intra-rater and test–retest reliability of an upper extremity sway test performed in the one-handed plank position on a force plate and to establish if there are any between-limb differe...

  • Article
  • Open Access
7 Citations
2,019 Views
11 Pages

Endovascular Revascularisation versus Open Surgery with Prosthetic Bypass for Femoro-Popliteal Lesions in Patients with Peripheral Arterial Disease

  • Gladiol Zenunaj,
  • Pierfilippo Acciarri,
  • Giulia Baldazzi,
  • Alessio Mario Cosacco,
  • Vincenzo Gasbarro and
  • Luca Traina

15 September 2023

Aim: Complex atherosclerotic femoro-popliteal lesions have traditionally been treated with bypass surgery. A prosthetic graft is used to save the vein graft for more distal revascularisations or when a vein graft is unavailable. The endovascular appr...

  • Article
  • Open Access
3 Citations
2,942 Views
15 Pages

25 July 2024

Pattern recognition (PR)-based myoelectric control systems can naturally provide multifunctional and intuitive control of upper limb prostheses and restore lost limb function, but understanding their robustness remains an open scientific question. Th...

  • Article
  • Open Access
1 Citations
1,659 Views
17 Pages

20 January 2025

Prefabricated insulation grid shear walls are a new type of wall which integrates structure, insulation and formwork. A grid-like reinforced concrete shear wall with vertical and transverse limbs is formed by casting concrete into the reserved vertic...

  • Article
  • Open Access
5 Citations
3,438 Views
12 Pages

Requirements and Solutions for Motion Limb Assistance of COVID-19 Patients

  • Marco Ceccarelli,
  • Matteo Bottin,
  • Matteo Russo,
  • Giulio Rosati,
  • Med Amine Laribi and
  • Victor Petuya

COVID-19 patients are strongly affected in terms of limb motion when imbedded during the acute phase of the infection, but also during the course of recovery therapies. Peculiarities are investigated for design requirements for medical devices in lim...

  • Article
  • Open Access
792 Views
10 Pages

Accuracy of Lower Extremity Alignment Correction Using Patient-Specific Cutting Guides and Anatomically Contoured Plates

  • Julia Matthias,
  • S Robert Rozbruch,
  • Austin T. Fragomen,
  • Anil S. Ranawat and
  • Taylor J. Reif

Background/Objectives: Limb malalignment disrupts physiological joint forces and predisposes individuals to the development of osteoarthritis. Surgical interventions such as distal femur or high tibial osteotomy aim to restore mechanical balance on w...

  • Article
  • Open Access
6 Citations
2,789 Views
18 Pages

1 November 2023

In this study, to establish the biomechanical characteristics of commercial vehicle drivers’ muscles and bones while operating the three pedals, a driver pedal-operation simulator was built, and the real-life situation was reconstructed in Open...

  • Article
  • Open Access
5 Citations
2,872 Views
13 Pages

Postural Stability in Athletes during Special Hurdle Tests without a Definite Dominant Leg

  • Bożena Wojciechowska-Maszkowska,
  • Ryszard Marcinów,
  • Janusz Iskra and
  • Rafał Tataruch

The purpose of this study was to analyze the body balance control of people walking and hurdling with or without a specific dominant leg in a monopodal position. This study involved 28 physical education students. The center of pressure (COP) was mea...

  • Communication
  • Open Access
6 Citations
3,777 Views
4 Pages

6 May 2022

In the past few years, there was a great interest in the use of higher doses of botulinum toxin type A, especially in case of upper and lower limb severe spasticity. To date, only one prospective, non-randomized, single-arm, multicenter, open-label,...

  • Case Report
  • Open Access
2 Citations
2,450 Views
7 Pages

8 March 2023

A 3-year-old male northern goshawk (Accipiter gentilis) used in falconry for hunting was diagnosed with a craniodorsal coxofemoral luxation of the left leg after an unsuccessful hunting flight. Closed reduction in the dislocation was unsuccessful and...

  • Article
  • Open Access
14 Citations
4,779 Views
8 Pages

Long-Term Outcomes following Common Femoral Endarterectomy

  • Takuya Hashimoto,
  • Satoshi Yamamoto,
  • Masaru Kimura,
  • Masaya Sano,
  • Osamu Sato and
  • Juno Deguchi

21 November 2022

Thromboendarterectomy of the common femoral artery (CFA) for occlusive disease is a crucial procedure in vascular surgery. As an outcome reference for emerging endovascular procedures and new devices, we need more robust evidence of the outcome of th...

  • Article
  • Open Access
535 Views
10 Pages

Background and Objective: This study presents a combined osteometric and biomechanical analysis of a Korean female cadaver exhibiting bilateral lower limb bone asymmetry with abnormal curvature and callus formation on the left femoral midshaft. Metho...

  • Article
  • Open Access
3 Citations
3,315 Views
14 Pages

9 October 2022

Cold-formed steel (CFS) is a typical green building material with the merits of being low-cost, lightweight, high-strength, and recyclable. CFS built-up section beams are widely used in CFS frames owing to their outstanding mechanical properties. How...

  • Article
  • Open Access
1,170 Views
11 Pages

miRNA in the Diagnosis and Treatment of Critical Limb Ischemia

  • Alexandra Ioana Popescu,
  • Andreea Luciana Rață,
  • Daliborca Vlad,
  • Cristian Vlad,
  • Roxana Popescu,
  • Ramona Roxana Onofrei,
  • Marialuisa Morelli,
  • Stelian Pantea and
  • Sorin Barac

Chronic threatening limb ischemia of the inferior limbs (CLTI) is the final stage of peripheral arterial disease (PAD) and is one of the most feared atherosclerotic manifestations because if left untreated, in time, it can lead to amputation. Althoug...

  • Communication
  • Open Access
3 Citations
2,606 Views
10 Pages

1 December 2023

Background: Agreement between the activities-specific balance confidence scale (ABC) and center of pressure (CoP) in prosthesis users is still very much unknown. The purpose of this study was to investigate the agreement between ABC and CoP in lower-...

  • Article
  • Open Access
1 Citations
3,190 Views
26 Pages

A Combined Mirror–EMG Robot-Assisted Therapy System for Lower Limb Rehabilitation

  • Florin Covaciu,
  • Bogdan Gherman,
  • Calin Vaida,
  • Adrian Pisla,
  • Paul Tucan,
  • Andrei Caprariu and
  • Doina Pisla

This paper presents the development and initial evaluation of a novel protocol for robot-assisted lower limb rehabilitation. It integrates dual-modal patient interaction, employing mirror therapy and an auto-adaptive EMG-driven control system, design...

  • Article
  • Open Access
43 Citations
4,985 Views
27 Pages

5 May 2020

Objective assessment of the motor evaluation test for Parkinson’s disease (PD) diagnosis is an open issue both for clinical and technical experts since it could improve current clinical practice with benefits both for patients and healthcare systems....

  • Article
  • Open Access
839 Views
11 Pages

Tibial Tubercle Avulsion Fracture in Young Athletes Surgically Treated: Mid-Long Term Result and Comparison

  • Lorenzo Moretti,
  • Carlo Amati,
  • Alessandro Geronimo,
  • Andrea Michele Abbaticchio,
  • Maria Paola Miolla,
  • Daniela Dibello and
  • Giuseppe Solarino

22 April 2025

Objectives: Tibial apophysis avulsion fracture is an unusual injury in young pediatric athletes. The mechanism of injury is often related to sports (i.e football and basketball). Fifteen patients who had this kind of fracture underwent surgical Open...

  • Article
  • Open Access
1,198 Views
14 Pages

11 August 2025

Upper-limb motor disabilities and amputation pose a significant burden on individuals, hindering their ability to perform daily activities independently. While various research studies aim to enhance the performance of current upper-limb prosthetic d...

  • Short Note
  • Open Access
2 Citations
4,030 Views
10 Pages

Synfolding calcite was precipitated between layers of Neoproterozoic sandy dolomite and striated parallel to the fold axis of an open anticline with a shallow plunge during folding. The fold had limb dips of 45° and plunged 20° to the south. The synf...

  • Article
  • Open Access
12 Citations
5,479 Views
18 Pages

Previous studies indicated that Fibroblast Growth Factors (FGFs) are present during tail and early limb regeneration in lizards, but FGFs disappear in the limb that turns into a scar and does not regenerate at 25–40 days post-amputation. Based on the...

of 8