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1,910 Results Found

  • Article
  • Open Access
117 Citations
15,676 Views
13 Pages

Children’s Anxiety and Factors Related to the COVID-19 Pandemic: An Exploratory Study Using the Children’s Anxiety Questionnaire and the Numerical Rating Scale

  • Marla Andréia Garcia de Avila,
  • Pedro Tadao Hamamoto Filho,
  • Francine Letícia da Silva Jacob,
  • Léia Regina Souza Alcantara,
  • Malin Berghammer,
  • Margaretha Jenholt Nolbris,
  • Patricia Olaya-Contreras and
  • Stefan Nilsson

The repercussions of the COVID-19 pandemic on children’s lives deserve attention. This study aimed to assess the prevalence of anxiety among Brazilian children and its associated factors during social distancing during COVID-19. We used a cross-secti...

  • Article
  • Open Access
2 Citations
1,941 Views
12 Pages

Availability of Observational Pain Assessment Tools in Hospitalized Patients with Osteoporotic Vertebral Fractures

  • Youhei Yoshimi,
  • Takanori Matsuura,
  • Kazuaki Miyazato,
  • Shiho Takahashi,
  • Nami Tanaka,
  • Hanae Morinaga,
  • Asuka Hayata,
  • Minami Onishi,
  • Yousuke Nagano and
  • Hideo Ohnishi

27 July 2024

Background and Objectives: Osteoporotic vertebral fractures in older patients cause lower back pain and abnormal posture, resulting in impaired activities of daily living (ADLs). Assessing pain using self-reported assessment tools is difficult, espec...

  • Article
  • Open Access
7 Citations
5,305 Views
20 Pages

17 September 2018

Generating energy from combustion is prone to pollutant formation. In energy systems working under non-premixed combustion mode, rapid mixing is required to increase the heat release rates. However, local extinction and re-ignition may occur, resulti...

  • Article
  • Open Access
10 Citations
3,569 Views
9 Pages

Correlation between the Neuropathic PainDETECT Screening Questionnaire and Pain Intensity in Chronic Pain Patients

  • Sebastian Lukas König,
  • Michal Prusak,
  • Sibylle Pramhas and
  • Marita Windpassinger

7 April 2021

Background and Objectives: Pain is a multidimensional phenomenon with a wide range regarding the location, intensity and quality. Patients with chronic pain, in particular those suffering from mixed pain, often present a special challenge. The PainDE...

  • Article
  • Open Access
2,023 Views
12 Pages

Combined Intra-Articular PN HPT™ and Hyaluronic Acid: Regeneration Medicine in Knee Osteoarthritis

  • Francesco Barcaro,
  • Alessandro Cerino,
  • Armando Francesco Cervini,
  • Mario Gaffuri,
  • Nikoleta Vaso and
  • Mario Vela

28 April 2025

Background/Objectives: Natural-origin PN HPT™ (Polynucleotides High Purification Technology) protect and revitalize chondrocytes, synoviocytes, and cartilage with a regenerative medicine perspective following intra-articular injection. This six...

  • Article
  • Open Access
422 Views
18 Pages

23 December 2025

Background/Objectives: Cervical spondylosis is a cause of recurrent neck pain, disability, and poor quality of life (QoL). This study aimed to examine the relationships among pain intensity, neck disability, functional performance, body mass index, a...

  • Article
  • Open Access
3 Citations
2,777 Views
10 Pages

A Quantitative Measure of Pain with Current Perception Threshold, Pain Equivalent Current, and Quantified Pain Degree: A Retrospective Study

  • So Yeon Lee,
  • Joong Baek Kim,
  • Jung Woong Lee,
  • A Mi Woo,
  • Chang Jae Kim,
  • Mee Young Chung and
  • Ho Sik Moon

23 August 2023

Background: As a subjective sensation, pain is difficult to evaluate objectively. The assessment of pain degree is largely dependent on subjective methods such as the numeric rating scale (NRS). The PainVisionTM system has recently been introduced as...

  • Article
  • Open Access
4 Citations
3,408 Views
22 Pages

The Complex Role of Botulinum Toxin in Enhancing Goal Achievement for Post-Stroke Patients

  • Miruna Ioana Săndulescu,
  • Delia Cinteză,
  • Daniela Poenaru,
  • Claudia-Gabriela Potcovaru,
  • Horia Păunescu and
  • Oana Andreia Coman

31 March 2024

Introduction. The rehabilitation medical team is responsible for the therapeutic management of post-stroke patients and, therefore, for the complex therapeutic approach of spasticity. Considering the generous arsenal at our disposal in terms of both...

  • Article
  • Open Access
1 Citations
6,175 Views
8 Pages

Characterization and Clinical Trial of an Innovative High-Speed Lancing Device

  • Ho Chang,
  • Yao-Jen Yeh,
  • Rahnfong Lee,
  • Chia-Chun Lee and
  • Jenq-Huey Shyu

18 April 2016

An innovative high-speed lancing device has a lancet that moves so fast that it is not affected at all by the vibration of its spring, and does not pierce the skin repeatedly, greatly reducing the pain that is caused to diabetes mellitus (DM) patient...

  • Article
  • Open Access
3 Citations
4,701 Views
11 Pages

Ultrasound (US)-guided cervical selective nerve root block (CSNRB) procedures are increasingly being performed as an alternative to conventional fluoroscopy (FL)-guided epidural injections for the treatment of cervical radicular pain. The aim of this...

  • Article
  • Open Access
6 Citations
25,678 Views
13 Pages

The intake of specific collagen peptides (SCPs) has been shown to decrease activity-related knee pain in young, physically active adults. This trial investigated the effect of a 12-week SCP supplementation in a wider age range of healthy men and wome...

  • Study Protocol
  • Open Access
10 Citations
7,401 Views
13 Pages

The Effect of Cannabis-Based Medicine on Neuropathic Pain and Spasticity in Patients with Multiple Sclerosis and Spinal Cord Injury: Study Protocol of a National Multicenter Double-Blinded, Placebo-Controlled Trial

  • Julie Schjødtz Hansen,
  • Rikke Middelhede Hansen,
  • Thor Petersen,
  • Stefan Gustavsen,
  • Annette Bang Oturai,
  • Finn Sellebjerg,
  • Eva Aggerholm Sædder,
  • Helge Kasch,
  • Peter Vestergaard Rasmussen and
  • Kristina Bacher Svendsen
  • + 1 author

14 September 2021

Disease or acquired damage to the central nervous system frequently causes disabling spasticity and central neuropathic pain (NP), both of which are frequent in multiple sclerosis (MS) and spinal cord injury (SCI). Patients with MS and SCI often requ...

  • Article
  • Open Access
31 Citations
4,279 Views
10 Pages

12 March 2023

Atopic dermatitis (AD) is a chronic inflammatory skin disease with severe itch. The eosinophil-to-lymphocyte ratio (ELR), neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR) are reported to...

  • Article
  • Open Access
2 Citations
3,248 Views
11 Pages

Pain Assessment and Analgesic Requirements after Sleeve Gastrectomy: A Comparison Study of Robotic versus Laparoscopic Approaches

  • Juan S. Barajas-Gamboa,
  • Mohammed Sakib Ihsan Khan,
  • Valentin Mocanu,
  • Jerry T. Dang,
  • Gustavo Romero-Velez,
  • Terrence Lee St-John,
  • Gabriel Diaz Del Gobbo,
  • A. Daniel Guerron,
  • Juan Pablo Pantoja and
  • Ricard Corcelles
  • + 4 authors

30 August 2024

Background: Sleeve gastrectomy is the most common bariatric procedure worldwide, yet postoperative pain management remains a concern. This study aimed to compare pain medication usage and pain scores between laparoscopic sleeve gastrectomy (LSG) and...

  • Article
  • Open Access
2 Citations
3,200 Views
11 Pages

Can Simple Tests Prior to Endoscopy Predict the OLGA Stage of Gastritis?

  • Ertan Bulbuloglu,
  • Hasan Dagmura,
  • Emin Daldal,
  • Alev Deresoy,
  • Huseyin Bakir,
  • Ugur Ozsoy,
  • Ali Ihsan Saglam and
  • Osman Demir

Gastritis is a progressive disease that evolves from a non-atrophic to atrophic state and progresses through intestinal metaplasia, with some cases leading eventually to gastric cancer. Since gastritis by definition is an inflammatory process of the...

  • Article
  • Open Access
11 Citations
4,800 Views
11 Pages

Pain Course after Total Knee Arthroplasty within a Standardized Pain Management Concept: A Prospective Observational Study

  • Melanie Schindler,
  • Stephanie Schmitz,
  • Jan Reinhard,
  • Petra Jansen,
  • Joachim Grifka and
  • Achim Benditz

4 December 2022

Background: Joint replacement surgeries have been known to be some of the most painful surgical procedures. Therefore, the options for postoperative pain management are of great importance for patients undergoing total knee arthroplasty (TKA). Despit...

  • Article
  • Open Access
1 Citations
3,108 Views
18 Pages

Immersive Virtual Reality-Based Exercise for Pain Management in Fibromyalgia: An Exploratory Study with Risk of Poor Outcomes Stratification

  • Claudio Carvajal-Parodi,
  • Gonzalo Arias-Álvarez,
  • David Ulloa-Díaz,
  • Luis Romero-Vera,
  • Oscar Andrades-Ramírez,
  • Francisco Guede-Rojas and
  • Jesús G. Ponce-González

26 May 2025

Fibromyalgia (FM) is characterized by persistent widespread pain that severely impacts quality of life. Immersive virtual reality-based exercise (iVRE) is emerging as a therapeutic modality for chronic pain management. However, research on iVRE in FM...

  • Article
  • Open Access
3 Citations
1,858 Views
22 Pages

Background/Objectives: Precisely selected patients require vitreoretinal surgeries (VRS) performed under general anesthesia (GA) when intravenous rescue opioid analgesics (IROA) are administered intraoperatively, despite a risk of adverse events, to...

  • Article
  • Open Access
2 Citations
2,790 Views
11 Pages

23 April 2024

Background and Objectives: The aim of this retrospective study was to evaluate the effect of lumbar sympathetic block (LSB) on pain scores, Fontaine Classification, and collateral perfusion status in patients with lower extremity peripheral artery di...

  • Article
  • Open Access
1,215 Views
18 Pages

15 April 2025

Background and Objectives: Prostatectomy is a common surgical procedure for prostate cancer, the most frequently diagnosed cancer in the male population. The choice of anaesthetic technique has a significant impact on postoperative pain management. T...

  • Article
  • Open Access
1 Citations
2,933 Views
13 Pages

Pain Self-Management with Inhaled Methoxyflurane by Emergency Department Trauma Patients: A Prospective, Interventional, Single-Center Study

  • Daniel Aiham Ghazali,
  • Donia Bouzid,
  • Alix Frachon,
  • Sarah Ait-Abdesselam,
  • Philippe Kenway,
  • Christophe Choquet and
  • Enrique Casalino

The coronavirus disease 2019 (COVID-19) pandemic has led to overcrowding in many emergency departments (EDs). The present single-center, prospective, interventional study (conducted at Bichat University Medical Center (Paris, France)) was designed to...

  • Systematic Review
  • Open Access
18 Citations
6,534 Views
13 Pages

Background: The concept of virtual reality (VR)-based rehabilitation therapy for treating people with low back pain is of growing research interest. However, the effectiveness of such therapy for pain reduction in clinical settings remains controvers...

  • Article
  • Open Access
4 Citations
3,242 Views
11 Pages

Endodontic Emergencies in Mumbai City during COVID-19 Lockdown and Different Phases of Unlock

  • Omkar Shinde,
  • Ajinkya M. Pawar,
  • Kulvinder Singh Banga,
  • Jatin Atram and
  • Dian Agustin Wahjuningrun

The present descriptive research focused on determining the traits of patients who required endodontic treatment during the COVID-19 lockdown and various stages of unlocking in Mumbai metropolitan region. The descriptive analysis was carried out by e...

  • Article
  • Open Access
3 Citations
1,152 Views
18 Pages

4 September 2025

Background/Objectives: Some patients undergoing vitreoretinal surgery (VRS) require general anesthesia (GA), despite the possibility of developing intolerable postoperative pain perception (IPPP). Intraoperative rescue opioid analgesia (IROA) adminis...

  • Article
  • Open Access
16 Citations
4,217 Views
13 Pages

Targeting IL-4 and IL-13 Receptors on Eosinophils in CRSwNP Patients: The Clinical Efficacy of Dupilumab

  • Giovanna Lucia Piazzetta,
  • Nadia Lobello,
  • Emanuela Chiarella,
  • Alberta Rizzuti,
  • Corrado Pelaia,
  • Girolamo Pelaia and
  • Nicola Lombardo

19 September 2023

Chronic rhinosinusitis with nasal polyposis (CRSwNP) is an inflammatory disease linked to type 2 inflammation. Several biologics have demonstrated therapeutic potential for the treatment of this pathology in which IL-4, IL-5 and IL-13 represent the m...

  • Article
  • Open Access
18 Citations
4,195 Views
13 Pages

Real-Life Effects of Omalizumab on Chronic Rhinosinusitis with Nasal Polyposis

  • Nicola Lombardo,
  • Giovanna Lucia Piazzetta,
  • Nadia Lobello,
  • Giuseppe Cicala,
  • Maria Patafi,
  • Anna Teresa Benincasa,
  • Corrado Pelaia,
  • Emanuela Chiarella and
  • Girolamo Pelaia

19 December 2023

Chronic rhinosinusitis with nasal polyposis (CRSwNP) is an inflammatory disease of the nasal and sinus mucosa. This inflammatory process is supported by a multitude of cytokines, including IL-4, IL-5, and IL-13 produced by Th2 cells, as well as by Ig...

  • Article
  • Open Access
7 Citations
2,560 Views
19 Pages

The Adequacy of Anesthesia Guidance for Vitreoretinal Surgeries with Preemptive Paracetamol/Metamizole

  • Michał Jan Stasiowski,
  • Anita Lyssek-Boroń,
  • Nikola Zmarzły,
  • Kaja Marczak and
  • Beniamin Oskar Grabarek

18 January 2024

Despite the possibility of postoperative pain occurrence, in some patients, vitreoretinal surgeries (VRSs) require performance of general anesthesia (GA). The administration of intraoperative intravenous rescue opioid analgesics (IROA) during GA cons...

  • Study Protocol
  • Open Access
1,565 Views
15 Pages

Background/Objectives: Complex regional pain syndrome (CRPS) is a primary pain condition that can develop in a limb after a trauma. Although the condition is rare, it may cause lifelong pain and disability. Evidence-based treatments are limited. Neur...

  • Article
  • Open Access
1 Citations
568 Views
17 Pages

14 November 2025

Background/Objectives: Postoperative nausea and vomiting (PONV) are common after general anesthesia (GA) and, in patients undergoing vitreoretinal surgery, may be triggered by the oculocardiac reflex (OCR) leading to the oculoemetic reflex (OER). Ina...

  • Article
  • Open Access
1 Citations
491 Views
13 Pages

1 December 2025

Background/Objectives: Intolerable postoperative pain perception (IPPP) may occur in patients undergoing vitreoretinal surgery (VRS), while general anesthesia (GA) is often preferred over regional techniques due to multiple contraindications. Intraop...

  • Article
  • Open Access
265 Views
13 Pages

3 January 2026

Background/Objectives: Postoperative nausea and vomiting (PONV) remains a frequent and clinically relevant complication following open lumbar discectomy (OLD) under general anesthesia. The present study represents a secondary, post hoc analysis of a...

  • Systematic Review
  • Open Access
6 Citations
4,056 Views
24 Pages

22 January 2024

Subjective pain assessment in cattle is contingent upon the observer’s experience and attitude. Studies of pain assessment in cattle by veterinarians and farmers using different pain scales have been published. This systematic review and meta-a...

  • Article
  • Open Access
5 Citations
3,425 Views
16 Pages

The Whole Process CFD Numerical Simulation of Flow Field and Suspended Solids Distribution in a Full-Scale High-Rate Clarifier

  • Qi Xu,
  • Xi Luo,
  • Chengjian Xu,
  • Yanlei Wan,
  • Guangcheng Xiong,
  • Hao Chen,
  • Qiuhong Zhou,
  • Dan Yan,
  • Xiang Li and
  • Huijuan Liu
  • + 1 author

26 August 2022

To further reduce the contents of phosphorus and suspended solids (SS) in the effluent, the high-rate clarifier is adopted by some wastewater treatment plants (WWTPs) to upgrade their processes. However, due to the complex phosphorus species and uncl...

  • Article
  • Open Access
2 Citations
1,516 Views
21 Pages

21 September 2024

In this study, the gas−particle flow field in a real-size industrial-scale micron air classifier manufactured by Phenikaa Group using 3D transient simulations with the FWC-RSM–DPM (Four-Way Coupling-Reynold Stress Model-Discrete Phase Mod...

  • Article
  • Open Access
8 Citations
2,612 Views
14 Pages

15 April 2022

The intersection behavior of hydraulic fractures and single natural fractures has been studied in detail; however, in fractured reservoirs, natural fractures are numerous and interlaced and the intersection of hydraulic fractures and multiple natural...

  • Creative
  • Open Access
1 Citations
3,070 Views
26 Pages

3 August 2020

The simplified model of numerical analyses of discrete dislocation motion and emission from a stressed source was applied to predict the yield stress, dislocation creep, and fatigue crack growth rate of metals dominated by dislocation motion. The res...

  • Article
  • Open Access
4 Citations
2,793 Views
15 Pages

Modelling and Numerical Simulation of a Compartment Fire: Flow Rate Behaviour at Opening

  • Ahmed El-kebir Iya,
  • Alban Fabrice Epée,
  • Philippe Onguéné Mvogo,
  • Justin Tégawendé Zaida and
  • Ruben Mouangue

3 May 2023

The modelling of fire behaviour in a compartment is the subject of this work. A small-scale experimental study was carried out in a compartment sized 0.5 m × 0.5 m × 0.5 m with a single door with a width of 0.2 m and a height of 0.4 m. Th...

  • Feature Paper
  • Article
  • Open Access
2 Citations
2,109 Views
17 Pages

12 October 2023

This work aims to identify the optimal rating scale for the rating system used by a credit insurance company subjected to the Solvency 2 regulatory framework. To do so, we apply and further develop a previously published result concerning the rating...

  • Article
  • Open Access
2,225 Views
14 Pages

13 August 2022

Flow configurations that maximize the instantaneous rate of conversion from potential to kinetic energy are sought using a combination of analytical and numerical methods. A hydrostatic model is briefly investigated, but the presence of unrealistic a...

  • Article
  • Open Access
1 Citations
3,029 Views
18 Pages

12 June 2020

In this work, the temporal–spatial evolution of kinetic and thermal energy dissipation rates in three-dimensional (3D) turbulent Rayleigh–Taylor (RT) mixing are investigated numerically by the lattice Boltzmann method. The temperature fie...

  • Article
  • Open Access
8 Citations
3,870 Views
16 Pages

7 August 2021

Olfactory self-assessments have been analyzed with often negative but also positive conclusions about their usefulness as a surrogate for sensory olfactory testing. Patients with nasal polyposis have been highlighted as a well-predisposed group for r...

  • Article
  • Open Access
15 Citations
7,067 Views
17 Pages

20 February 2017

Spatial heterogeneity in soil properties has been a challenge for providing field-scale estimates of infiltration rates and surface soil moisture content over natural fields. In this study, we develop analytical expressions for effective saturated hy...

  • Article
  • Open Access
4 Citations
2,337 Views
19 Pages

3 November 2020

This paper presents a numerical two-scale framework for the simulation of fiber reinforced concrete under impact loading. The numerical homogenization framework considers the full balance of linear momentum at the microscale. This allows for the stud...

  • Article
  • Open Access
15 Citations
3,806 Views
21 Pages

10 February 2021

This work aims at bridging experimental and numerical approaches to determine the optimal operating parameters for the fabrication of well-shaped polyvinylpyrrolidone (PVP) particles via electrohydrodynamic atomization. Particular emphasis is given t...

  • Article
  • Open Access
13 Citations
3,652 Views
15 Pages

Hybrid rockets are considered a promising future propulsion alternative for specific applications to solid or liquid rockets. In order to raise their technology readiness level, it is important to perform predictive numerical simulations of their int...

  • Article
  • Open Access
4 Citations
4,863 Views
11 Pages

A Forehead Wearable Sensor for the Objective Measurement of Chronic Pain

  • Marcus Orzabal,
  • Ramo Naidu,
  • Kasra Amirdelfan and
  • Alireza Akhbardeh

Chronic pain impacts one in five Americans and is difficult to manage, costing ~USD 600 billion annually. The subjective experience of pain is a complex processing of central nervous system input. Recent advances in magnetic resonance imaging reveale...

  • Review
  • Open Access
26 Citations
5,918 Views
15 Pages

This paper reviews the recent development of numerical modelling of local scour around hydraulic and marine structures. The numerical models for simulating local scour are classified into five categories: sediment transport rate models, two-phase mod...

  • Article
  • Open Access
946 Views
11 Pages

12 February 2025

Background/Objectives: Biosimilar studies use overall response rate to assess clinical similarity. Sample size and power depend on the equivalence margin, defined in either risk difference or risk ratio scale. This manuscript investigates how differe...

  • Article
  • Open Access
1,327 Views
24 Pages

23 January 2025

This study systematically performs multi-scale numerical investigation of supercritical CO2-energized fracturing, widely employed for enhanced oil recovery (EOR) in tight oil and gas reservoirs. Two distinct models, spanning from core scale to field...

  • Article
  • Open Access
2 Citations
1,774 Views
22 Pages

24 October 2024

The model error is a direct reflection of the accuracy of the model simulation. However, it is challenging to estimate the model error due to the presence of numerous uncertainties inherent to the atmospheric and soil data, as well as the structure a...

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