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1,289 Results Found

  • Article
  • Open Access
272 Views
23 Pages

11 December 2025

Multimodal optimization is characterized by the dual imperative of achieving global peak diversity and local precision enhancement for discovered solutions. An adaptive memetic differential evolution is proposed in this work based on the virtual popu...

  • Article
  • Open Access
1,071 Views
26 Pages

30 November 2024

The electronic control module is an important part of a digital electronic detonator, which undergoes a complex production process that includes three electrical performance tests and three visual inspection procedures. In each inspection procedure,...

  • Article
  • Open Access
2 Citations
1,129 Views
37 Pages

10 February 2025

To strengthen the population diversity and search capability of equilibrium optimizer (EO), a dynamic multi-population mutation architecture-based equilibrium optimizer (DMMAEO) is proposed. Firstly, a dynamic multi-population guidance mechanism is c...

  • Article
  • Open Access
3 Citations
2,794 Views
33 Pages

7 November 2022

Differential Evolution (DE) has been extensively adopted for multi-objective optimization due to its efficient and straightforward framework. In DE, the mutation operator influences the evolution of the population. In this paper, an adaptive Grid-bas...

  • Article
  • Open Access
39 Citations
12,350 Views
16 Pages

4 February 2019

Obtaining high convergence and uniform distributions remains a major challenge in most metaheuristic multi-objective optimization problems. In this article, a novel multi-objective particle swarm optimization (PSO) algorithm is proposed based on Gaus...

  • Article
  • Open Access
176 Views
43 Pages

29 December 2025

Due to the complexity of multi-objective engineering problems, solutions obtained by many algorithms often exhibit poor distribution, and the algorithms tend to fall into local optima. To effectively alleviate these issues, an improved multi-objectiv...

  • Article
  • Open Access
15 Citations
4,018 Views
27 Pages

29 December 2018

Particle swarm optimization (PSO) is one of the most popular, nature inspired optimization algorithms. The canonical PSO is easy to implement and converges fast, however, it suffers from premature convergence. The comprehensive learning particle swar...

  • Article
  • Open Access
10 Citations
2,351 Views
23 Pages

8 November 2022

In this work, we propose a new test case generation approach that can cover behavioural scenarios individually in a multi-agent system. The purpose is to identify, in the case of the detection of an error, the scenario that caused the detected error,...

  • Article
  • Open Access
15 Citations
4,004 Views
28 Pages

29 September 2019

In this research, a novel enhanced gravitational search algorithm (EGSA) is proposed to resolve the multi-objective optimization model, considering the power generation of a hydropower enterprise and the peak operation requirement of a power system....

  • Article
  • Open Access
7 Citations
3,140 Views
20 Pages

11 July 2022

Mine extraction planning has a far-reaching impact on the production management and overall economic efficiency of the mining enterprise. The traditional method of preparing underground mine production planning is complicated and tedious, and reachin...

  • Article
  • Open Access
10 Citations
4,283 Views
19 Pages

Frequency of Pathogenic Germline Mutations in Early and Late Onset Familial Breast Cancer Patients Using Multi-Gene Panel Sequencing: An Egyptian Study

  • Auhood Nassar,
  • Abdel-Rahman N. Zekri,
  • Mahmoud M. Kamel,
  • Mostafa H. Elberry,
  • Mai M. Lotfy,
  • Mohamed G. Seadawy,
  • Zeinab K. Hassan,
  • Hany K. Soliman,
  • Ahmed M. Lymona and
  • Amira Salah El-Din Youssef

29 December 2022

Background: Precision oncology has been increasingly used in clinical practice and rapidly evolving in the oncology field. Thus, this study was performed to assess the frequency of germline mutations in early and late onset familial breast cancer (BC...

  • Article
  • Open Access
666 Views
15 Pages

16 October 2025

Cold rolling is the precision finishing stage in the steel production process, and its scheduling optimization is essential for enhancing production efficiency. To address the complex process constraints and objectives, this paper proposes a multi-gr...

  • Article
  • Open Access
29 Citations
4,311 Views
22 Pages

A quick and effective way of segmenting images is the Otsu threshold method. However, the complexity of time grows exponentially as the number of thresolds rises. The aim of this study is to address the issues with the standard threshold image segmen...

  • Article
  • Open Access
13 Citations
5,493 Views
12 Pages

19 July 2018

Emergence of human immunodeficiency virus type 1 (HIV-1) drug resistance arises from mutation fixation in the viral genome during antiretroviral therapy. Primary mutations directly confer antiviral drug resistance, while secondary mutations arise tha...

  • Article
  • Open Access
4 Citations
1,590 Views
31 Pages

8 December 2022

Marine Predator Algorithm (MPA) is a meta-heuristic algorithm based on the foraging behavior of marine animals. It has the advantages of few parameters, simple setup, easy implementation, accurate calculation, and easy application. However, compared...

  • Article
  • Open Access
2 Citations
2,018 Views
24 Pages

9 August 2022

The intelligent manufacturing of power systems has led to many challenges. The cyber-physical system (CPS) was introduced to solve the problem of insufficient integration of equipment and systems. It brings advantages, but also risks. In the distribu...

  • Article
  • Open Access
14 Citations
2,918 Views
15 Pages

6 June 2022

Aiming at solving the problems of large calculation, time-consuming, and low segmentation accuracy of multi-threshold image segmentation, an adaptive threshold value based differential evolution algorithm is proposed in this paper. Firstly, an opposi...

  • Article
  • Open Access
16 Citations
2,441 Views
14 Pages

30 November 2022

The IDH somatic mutation status is an important basis for the diagnosis and classification of gliomas. We proposed a “6-Step” general radiomics model to noninvasively predict the IDH mutation status by simultaneously tuning combined multi...

  • Article
  • Open Access
282 Views
36 Pages

31 December 2025

Target assignment is a core issue in command and control, aiming to rationally distribute targets among multiple coordinated operational units based on battlefield conditions to maximize overall operational effectiveness. This study proposes a target...

  • Article
  • Open Access
8 Citations
1,966 Views
16 Pages

25 September 2023

In the context of carbon peaking and carbon neutralization, distributed photovoltaics is a relatively mature new energy power generation technology that is being widely promoted. However, the randomness and volatility of distributed generation bring...

  • Article
  • Open Access
22 Citations
3,430 Views
21 Pages

Mechanism of Land Subsidence Mutation in Beijing Plain under the Background of Urban Expansion

  • Lin Guo,
  • Huili Gong,
  • Yinghai Ke,
  • Lin Zhu,
  • Xiaojuan Li,
  • Mingyuan Lyu and
  • Ke Zhang

5 August 2021

Under the background of over-exploitation of groundwater and urban expansion, the land subsidence in the Beijing Plain has dramatically increased recently, and has demonstrated obvious mutation characteristics. Firstly, this paper used the land-use t...

  • Article
  • Open Access
6 Citations
3,866 Views
9 Pages

Hunting for Familial Parkinson’s Disease Mutations in the Post Genome Era

  • Steven R. Bentley,
  • Ilaria Guella,
  • Holly E. Sherman,
  • Hannah M. Neuendorf,
  • Alex M. Sykes,
  • Javed Y. Fowdar,
  • Peter A. Silburn,
  • Stephen A. Wood,
  • Matthew J. Farrer and
  • George D. Mellick

17 March 2021

Parkinson’s disease (PD) is typically sporadic; however, multi-incident families provide a powerful platform to discover novel genetic forms of disease. Their identification supports deciphering molecular processes leading to disease and may inform o...

  • Article
  • Open Access
11 Citations
3,240 Views
18 Pages

Combining Multi-Shell Diffusion with Conventional MRI Improves Molecular Diagnosis of Diffuse Gliomas with Deep Learning

  • Golestan Karami,
  • Riccardo Pascuzzo,
  • Matteo Figini,
  • Cosimo Del Gratta,
  • Hui Zhang and
  • Alberto Bizzi

12 January 2023

The WHO classification since 2016 confirms the importance of integrating molecular diagnosis for prognosis and treatment decisions of adult-type diffuse gliomas. This motivates the development of non-invasive diagnostic methods, in particular MRI, to...

  • Article
  • Open Access
1 Citations
2,856 Views
19 Pages

Edge-Weighted Consensus-Based Formation Control with Collision Avoidance for Mobile Robots Based on Multi-Strategy Mutation Differential Evolution

  • Jesus Hernandez-Barragan,
  • Tonatiuh Hernandez,
  • Jorge D. Rios,
  • Marco Perez-Cisneros and
  • Alma Y. Alanis

23 August 2023

An edge-weighted consensus-based formation control strategy is presented for mobile robots. In the edge-weighted strategy, a desired formation pattern is achieved by adjusting gain weights related to the distance between robots. Moreover, the edge-we...

  • Article
  • Open Access
13 Citations
5,836 Views
18 Pages

Transcriptome Patterns of BRCA1- and BRCA2- Mutated Breast and Ovarian Cancers

  • Arsen Arakelyan,
  • Ani Melkonyan,
  • Siras Hakobyan,
  • Uljana Boyarskih,
  • Arman Simonyan,
  • Lilit Nersisyan,
  • Maria Nikoghosyan,
  • Maxim Filipenko and
  • Hans Binder

28 January 2021

Mutations in the BRCA1 and BRCA2 genes are known risk factors and drivers of breast and ovarian cancers. So far, few studies have been focused on understanding the differences in transcriptome and functional landscapes associated with the disease (br...

  • Article
  • Open Access
5 Citations
3,605 Views
23 Pages

13 April 2022

Pancreatic Ductal adenocarcinoma (PDAC) is an aggressive cancer commonly exhibiting KRAS-activating mutations. Alcohol contributes to the risk of developing PDAC in humans, and murine models have shown alcohol consumption in the context of KRAS mutat...

  • Article
  • Open Access
4 Citations
2,241 Views
24 Pages

15 June 2023

By addressing the flexible job shop scheduling problem (FJSP), this paper proposes a new type of algorithm for the FJSP. We named it the hybrid coronavirus population immunity optimization algorithm. Based on the characteristics of the problem, first...

  • Article
  • Open Access
179 Views
32 Pages

29 December 2025

To solve the multi-objective optimization problem (MOP) for parameter optimization of a multiple spacecraft attitude controller, an improved multi-objective moth–flame optimization algorithm based on r-domination (rIMOMFO) is proposed. In rIMOM...

  • Article
  • Open Access
5 Citations
3,896 Views
19 Pages

Somatic heterozygous mutations in the active site of the enhancer of zeste homolog 2 (EZH2) are prevalent in diffuse large B-cell lymphoma (DLBCL) and acute myeloid leukemia (AML). The methyltransferase activity of EZH2 towards lysine 27 on histone H...

  • Article
  • Open Access
4 Citations
1,782 Views
15 Pages

An Intelligent Cost-Reference Particle Filter with Resampling of Multi-Population Cooperation

  • Xinyu Zhang,
  • Mengjiao Ren,
  • Jiemin Duan,
  • Yingmin Yi,
  • Biyu Lei and
  • Shuyue Wu

22 July 2023

Although the cost-reference particle filter (CRPF) has a good advantage in solving the state estimation problem with unknown noise statistical characteristics, its estimation accuracy is still affected by the lack of particle diversity and sensitivit...

  • Article
  • Open Access
871 Views
28 Pages

29 October 2025

Three-dimensional path planning in emergency logistics is a complex optimization problem, particularly challenging because it requires considering conflicting objectives such as flight time, energy consumption, and obstacle avoidance. Unlike most urb...

  • Article
  • Open Access
12 Citations
5,047 Views
15 Pages

11 March 2019

In the real word, optimization problems in multi-objective optimization (MOP) and dynamic optimization can be seen everywhere. During the last decade, among various swarm intelligence algorithms for multi-objective optimization problems, glowworm swa...

  • Article
  • Open Access
8 Citations
3,519 Views
19 Pages

Modified Whale Optimization Algorithm for Multi-Type Combine Harvesters Scheduling

  • Wenqiang Yang,
  • Zhile Yang,
  • Yonggang Chen and
  • Zhanlei Peng

17 January 2022

The optimal scheduling of multi-type combine harvesters is a crucial topic in improving the operating efficiency of combine harvesters. Due to the NP-hard property of this problem, developing appropriate optimization approaches is an intractable task...

  • Article
  • Open Access
1 Citations
3,408 Views
17 Pages

A Multi-Agent Motion Prediction and Tracking Method Based on Non-Cooperative Equilibrium

  • Yan Li,
  • Mengyu Zhao,
  • Huazhi Zhang,
  • Yuanyuan Qu and
  • Suyu Wang

5 January 2022

A Multi-Agent Motion Prediction and Tracking method based on non-cooperative equilibrium (MPT-NCE) is proposed according to the fact that some multi-agent intelligent evolution methods, like the MADDPG, lack adaptability facing unfamiliar environment...

  • Article
  • Open Access
887 Views
17 Pages

7 November 2025

Background: Levofloxacin is a broad-spectrum third-generation fluoroquinolone with bactericidal activity against Streptococcus species. We aimed to investigate the susceptibility rates of levofloxacin, the genetic determinants contributing to resista...

  • Review
  • Open Access
15 Citations
3,963 Views
50 Pages

Precision neurosurgery is rapidly evolving as a medical specialty by merging genomic medicine, multi-omics technologies, and artificial intelligence (AI) technology, while at the same time, society is shifting away from the traditional, anatomic mode...

  • Article
  • Open Access
1 Citations
890 Views
35 Pages

20 June 2025

This study proposes an improved multi-objective black-winged kite algorithm (MOBKA-QL) integrating Q-learning with adaptive mutation strategies for optimizing multi-objective scheduling in integrated energy systems (IES). The algorithm dynamically se...

  • Article
  • Open Access
1 Citations
1,747 Views
24 Pages

Dynamic Niches-Based Hybrid Breeding Optimization Algorithm for Solving Multi-Modal Optimization Problem

  • Ting Cai,
  • Ziteng Qiao,
  • Zhiwei Ye,
  • Hu Pan,
  • Mingwei Wang,
  • Wen Zhou,
  • Qiyi He,
  • Peng Zhang and
  • Wanfang Bai

8 September 2024

Some problems exist in classical optimization algorithms to solve multi-modal optimization problems and other complex systems. A Dynamic Niches-based Improved Hybrid Breeding Optimization (DNIHBO) algorithm is proposed to address the multi-modal opti...

  • Review
  • Open Access
15 Citations
6,822 Views
24 Pages

Multi-Gene Testing Overview with a Clinical Perspective in Metastatic Triple-Negative Breast Cancer

  • Martina Dameri,
  • Lorenzo Ferrando,
  • Gabriella Cirmena,
  • Claudio Vernieri,
  • Giancarlo Pruneri,
  • Alberto Ballestrero and
  • Gabriele Zoppoli

Next-generation sequencing (NGS) is the technology of choice for the routine screening of tumor samples in clinical practice. In this setting, the targeted sequencing of a restricted number of clinically relevant genes represents the most practical o...

  • Article
  • Open Access
39 Citations
5,691 Views
17 Pages

6 February 2018

In the past two decades, China’s manufacturing industry has achieved great success. However, pollution and environmental impacts have become more serious while this industry has grown. The economic and emission dispatch (EED) problem is a typical mul...

  • Article
  • Open Access
61 Citations
5,779 Views
17 Pages

Molecular Diagnostic of Solid Tumor Using a Next Generation Sequencing Custom-Designed Multi-Gene Panel

  • Dario de Biase,
  • Giorgia Acquaviva,
  • Michela Visani,
  • Viviana Sanza,
  • Chiara M. Argento,
  • Antonio De Leo,
  • Thais Maloberti,
  • Annalisa Pession and
  • Giovanni Tallini

Next generation sequencing (NGS) allows parallel sequencing of multiple genes at a very high depth of coverage. The need to analyze a variety of targets for diagnostic/prognostic/predictive purposes requires multi-gene characterization. Multi-gene pa...

  • Article
  • Open Access
1 Citations
1,035 Views
33 Pages

2 April 2025

Amid the rapid growth of the new energy vehicle industry and the accelerating global shift toward green and low-carbon energy alternatives, this paper develops a multi-objective optimization model for an Electric Vehicle Integrated Energy Station (EV...

  • Article
  • Open Access
33 Citations
2,336 Views
20 Pages

28 March 2024

Currently, the multi-machine collaboration of agricultural machinery is one of the international frontiers and a topic of research interest in the field of agricultural equipment. However, the multi-machine cooperative operation of agricultural machi...

  • Article
  • Open Access
10 Citations
4,941 Views
17 Pages

Effective Improved NSGA-II Algorithm for Multi-Objective Integrated Process Planning and Scheduling

  • Xiaoyu Wen,
  • Qingbo Song,
  • Yunjie Qian,
  • Dongping Qiao,
  • Haoqi Wang,
  • Yuyan Zhang and
  • Hao Li

15 August 2023

Integrated process planning and scheduling (IPPS) is important for modern manufacturing companies to achieve manufacturing efficiency and improve resource utilization. Meanwhile, multiple objectives need to be considered in the realistic decision-mak...

  • Article
  • Open Access
2 Citations
3,362 Views
30 Pages

13 December 2024

In the distribution field, distribution costs and customer service satisfaction are extremely important issues for enterprises. However, both the Vehicle Routing Problem with Soft Time Windows (VRPSTW) and the Vehicle Routing Problem with Fuzzy Time...

  • Article
  • Open Access
567 Views
27 Pages

Improvement of Premium Oil Soybean Variety Heinong 551 with Integrating Conventional Hybridization and Gamma Radiation

  • Xiulin Liu,
  • Xueyang Wang,
  • Kezhen Zhao,
  • Chunlei Zhang,
  • Fengyi Zhang,
  • Rongqiang Yuan,
  • Sobhi F. Lamlom,
  • Honglei Ren and
  • Bixian Zhang

16 October 2025

Meeting the growing demand for vegetable oil while promoting agricultural sustainability in Northeast China requires developing high-yield, high-oil-content soybean varieties. We present the comprehensive development and evaluation of Heinong 551, an...

  • Article
  • Open Access
2 Citations
2,019 Views
16 Pages

13 September 2023

We propose a computational framework for selecting biologically plausible genes identified by clustering of multi-omics data that reveal patients’ similarity, thus giving researchers a more comprehensive view on any given disease. We employ spe...

  • Article
  • Open Access
18 Citations
3,533 Views
27 Pages

7 July 2023

The application of 3D UAV path planning algorithms in smart cities and smart buildings can improve logistics efficiency, enhance emergency response capabilities as well as provide services such as indoor navigation, thus bringing more convenience and...

  • Article
  • Open Access
10 Citations
4,803 Views
20 Pages

31 August 2023

Lesch–Nyhan syndrome (LN) is an is an X-linked recessive inborn error of metabolism that arises from a deficiency of purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT). The disease manifests severely, causing intellectu...

  • Article
  • Open Access
22 Citations
5,039 Views
42 Pages

The African Vulture Optimization Algorithm (AVOA) is inspired by African vultures’ feeding and orienting behaviors. It comprises powerful operators while maintaining the balance of exploration and efficiency in solving optimization problems. To...

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