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553 Results Found

  • Review
  • Open Access
58 Citations
10,766 Views
18 Pages

27 June 2013

Schizophrenia is a complex chronic mental illness that is characterized by positive, negative and cognitive symptoms. Cognitive deficits are most predictive of long-term outcomes, with abnormalities in memory being the most robust finding. The adven...

  • Article
  • Open Access
7 Citations
5,649 Views
18 Pages

Gulf War Illness (GWI) is a debilitating condition characterized by dysfunction of cognition, pain, fatigue, sleep, and diverse somatic symptoms with no known underlying pathology. As such, uncovering objective biomarkers such as differential regions...

  • Review
  • Open Access
2 Citations
3,830 Views
16 Pages

Functional MRI in Radiology—A Personal Review

  • Martin Lotze,
  • Martin Domin,
  • Sönke Langner and
  • Thomas Platz

29 August 2022

We, here, provide a personal review article on the development of a functional MRI in the radiology departments of two German university medicine units. Although the international community for human brain mapping has met since 1995, the researchers...

  • Article
  • Open Access
2 Citations
7,289 Views
15 Pages

A Multimodal Magnetic Resonance Imaging Study on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Feasibility and Clinical Correlation

  • Raminder Kaur,
  • Brian Greeley,
  • Alexander Ciok,
  • Kashish Mehta,
  • Melody Tsai,
  • Hilary Robertson,
  • Kati Debelic,
  • Lan Xin Zhang,
  • Todd Nelson and
  • Travis Boulter
  • + 3 authors

22 August 2024

Background/Objectives: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a neurological disorder characterized by post-exertional malaise. Despite its clinical relevance, the disease mechanisms of ME/CFS are not fully understood. The pre...

  • Brief Report
  • Open Access
8 Citations
5,530 Views
14 Pages

Topics: Functional Magnetic Resonance Imaging (fMRI) evaluation of HyberBaric Oxygen Therapy (HBOT) effects on chronic cerebral stroke Patients (Pts). Introduction: Our aim was to evaluate with fMRI, in a 3 Tesla system, the functional effects of HBO...

  • Review
  • Open Access
10 Citations
7,089 Views
12 Pages

One of the challenges of managing athletes with sport-related concussion (SRC) is guiding them to a safe return to play. A potential biomarker for use in the clinical assessment of recovery is the analysis of brain activation patterns during task-rel...

  • Review
  • Open Access
15 Citations
6,873 Views
18 Pages

Optogenetic fMRI for Brain-Wide Circuit Analysis of Sensory Processing

  • Jeong-Yun Lee,
  • Taeyi You,
  • Choong-Wan Woo and
  • Seong-Gi Kim

14 October 2022

Sensory processing is a complex neurological process that receives, integrates, and responds to information from one’s own body and environment, which is closely related to survival as well as neurological disorders. Brain-wide networks of sens...

  • Article
  • Open Access
2,185 Views
19 Pages

Zero-Shot Neural Decoding with Semi-Supervised Multi-View Embedding

  • Yusuke Akamatsu,
  • Keisuke Maeda,
  • Takahiro Ogawa and
  • Miki Haseyama

3 August 2023

Zero-shot neural decoding aims to decode image categories, which were not previously trained, from functional magnetic resonance imaging (fMRI) activity evoked when a person views images. However, having insufficient training data due to the difficul...

  • Systematic Review
  • Open Access
12 Citations
7,366 Views
23 Pages

Graph-Based Analysis of Brain Connectivity in Multiple Sclerosis Using Functional MRI: A Systematic Review

  • Sara Hejazi,
  • Waldemar Karwowski,
  • Farzad V. Farahani,
  • Tadeusz Marek and
  • P. A. Hancock

31 January 2023

(1) Background: Multiple sclerosis (MS) is an immune system disease in which myelin in the nervous system is affected. This abnormal immune system mechanism causes physical disabilities and cognitive impairment. Functional magnetic resonance imaging...

  • Article
  • Open Access
13 Citations
3,777 Views
9 Pages

Functional Magnetic Resonance Imaging in the Olfactory Perception of the Same Stimuli

  • Andrea Ciorba,
  • Stavros Hatzopoulos,
  • Cristina Cogliandolo,
  • Chiara Bianchini,
  • Martina Renna,
  • Luca Perrucci,
  • Magdalena Skarzynska,
  • Piotr Henryk Skarżyński,
  • Paolo Campioni and
  • Corrado Cittanti
  • + 3 authors

25 December 2020

Background. Data in the literature report that a number of studies have attempted to identify the exact location of the cortical olfaction representation, searching for evidence suggesting that sniffing odors can initiate a primary activation of the...

  • Article
  • Open Access
11 Citations
4,498 Views
16 Pages

An fMRI Compatible Smart Device for Measuring Palmar Grasping Actions in Newborns

  • Daniela Lo Presti,
  • Sofia Dall’Orso,
  • Silvia Muceli,
  • Tomoki Arichi,
  • Sara Neumane,
  • Anna Lukens,
  • Riccardo Sabbadini,
  • Carlo Massaroni,
  • Michele Arturo Caponero and
  • Domenico Formica
  • + 2 authors

23 October 2020

Grasping is one of the first dominant motor behaviors that enable interaction of a newborn infant with its surroundings. Although atypical grasping patterns are considered predictive of neuromotor disorders and injuries, their clinical assessment suf...

  • Article
  • Open Access
2,854 Views
20 Pages

Decoding Mental States in Social Cognition: Insights from Explainable Artificial Intelligence on HCP fMRI Data

  • José Diogo Marques dos Santos,
  • Luís Paulo Reis and
  • José Paulo Marques dos Santos

Artificial neural networks (ANNs) have been used for classification tasks involving functional magnetic resonance imaging (fMRI), though typically focusing only on fractions of the brain in the analysis. Recent work combined shallow neural networks (...

  • Article
  • Open Access
13 Citations
3,745 Views
16 Pages

6 December 2023

Autism spectrum disorder (ASD) poses as a multifaceted neurodevelopmental condition, significantly impacting children’s social, behavioral, and communicative capacities. Despite extensive research, the precise etiological origins of ASD remain...

  • Article
  • Open Access
1,922 Views
19 Pages

Safety of Simultaneous Scalp and Intracranial EEG and fMRI: Evaluation of RF-Induced Heating

  • Hassan B. Hawsawi,
  • Anastasia Papadaki,
  • Vejay N. Vakharia,
  • John S. Thornton,
  • David W. Carmichael,
  • Suchit Kumar and
  • Louis Lemieux

The acquisition of electroencephalography (EEG) concurrently with functional magnetic resonance imaging (fMRI) requires a careful consideration of the health hazards resulting from interactions between the scanner’s electromagnetic fields and E...

  • Article
  • Open Access
3 Citations
3,487 Views
14 Pages

Background: Theory of Mind (ToM) is an ability to infer the mental state of others, which plays an important role during social events. Previous studies have shown that ToM deficits exist frequently in schizophrenia, which may result from abnormal ac...

  • Article
  • Open Access
46 Citations
12,434 Views
23 Pages

7 February 2022

Brain neural activity decoding is an important branch of neuroscience research and a key technology for the brain–computer interface (BCI). Researchers initially developed simple linear models and machine learning algorithms to classify and rec...

  • Article
  • Open Access
16 Citations
7,790 Views
12 Pages

Reliability of Fronto–Amygdala Coupling during Emotional Face Processing

  • Camilla L Nord,
  • Alan Gray,
  • Oliver J Robinson and
  • Jonathan P Roiser

One of the most exciting translational prospects for brain imaging research is the potential use of functional magnetic resonance imaging (fMRI) ‘biomarkers’ to predict an individual’s risk of developing a neuropsychiatric disorder or the likelihood...

  • Review
  • Open Access
46 Citations
14,221 Views
11 Pages

Fibromyalgia is characterized by chronic widespread pain and several additional symptoms such as fatigue, cognitive dysfunction, depressive episodes, and anxiety. The underlying pathophysiology of fibromyalgia is still poorly understood, and treatmen...

  • Article
  • Open Access
5 Citations
5,542 Views
11 Pages

Longitudinal Volumetric Assessment of Ventricular Enlargement in Pet Dogs Trained for Functional Magnetic Resonance Imaging (fMRI) Studies

  • Eva Gunde,
  • Kálmán Czeibert,
  • Anna Gábor,
  • Dóra Szabó,
  • Anna Kis,
  • Attila Arany-Tóth,
  • Attila Andics,
  • Márta Gácsi and
  • Enikő Kubinyi

4 September 2020

Background: Recent studies suggest that clinically sound ventriculomegaly in dogs could be a preliminary form of the clinically significant hydrocephalus. We evaluated changes of ventricular volumes in awake functional magnetic resonance imaging (fMR...

  • Article
  • Open Access
3 Citations
3,524 Views
13 Pages

28 April 2023

Multimodal functional near-infrared spectroscopy–functional magnetic resonance imaging (fNIRS–fMRI) studies have been highly beneficial for both the fNIRS and fMRI field as, for example, they shed light on the underlying mechanism of each...

  • Review
  • Open Access
2 Citations
4,763 Views
18 Pages

fMRI Insights into Visual Cortex Dysfunction as a Biomarker for Migraine with Aura

  • Damian Pikor,
  • Natalia Banaszek-Hurla,
  • Alicja Drelichowska,
  • Mikołaj Hurla,
  • Jolanta Dorszewska,
  • Tomasz Wolak and
  • Wojciech Kozubski

Migraine with aura (MwA) is a common and severely disabling neurological disorder, characterised by transient yet recurrent visual disturbances, including scintillating scotomas, flickering photopsias, and complex geometric patterns. These episodic v...

  • Article
  • Open Access
12 Citations
5,593 Views
28 Pages

Effect of SSRIs on Resting-State Functional Brain Networks in Adolescents with Major Depressive Disorder

  • Shu-Hsien Chu,
  • Keshab K. Parhi,
  • Melinda Westlund Schreiner,
  • Christophe Lenglet,
  • Bryon A. Mueller,
  • Bonnie Klimes-Dougan and
  • Kathryn R. Cullen

23 September 2021

Investigation of brain changes in functional connectivity and functional network topology from receiving 8-week selective serotonin reuptake inhibitor (SSRI) treatments is conducted in 12 unmedicated adolescents with major depressive disorder (MDD) b...

  • Article
  • Open Access
1,892 Views
17 Pages

Continuous Dictionary of Nodes Model and Bilinear-Diffusion Representation Learning for Brain Disease Analysis

  • Jiarui Liang,
  • Tianyi Yan,
  • Yin Huang,
  • Ting Li,
  • Songhui Rao,
  • Hongye Yang,
  • Jiayu Lu,
  • Yan Niu,
  • Dandan Li and
  • Jie Xiang
  • + 1 author

13 August 2024

Brain networks based on functional magnetic resonance imaging (fMRI) provide a crucial perspective for diagnosing brain diseases. Representation learning has recently attracted tremendous attention due to its strong representation capability, which c...

  • Review
  • Open Access
542 Views
14 Pages

Innovations in Meta-Analytic and Computational Methods in the Neuroscientific Investigation of Psychiatric and Neurological Disorders

  • Chris H. Miller,
  • Thomas J. Farrer,
  • Jonathan D. Moore,
  • Matthew J. Wright,
  • Caitlin Baten,
  • Ellen Woo,
  • J. Paul Hamilton,
  • Matthew D. Sacchet,
  • Lance D. Erickson and
  • Shawn D. Gale
  • + 1 author

12 December 2025

Recent advancements in neuroimaging and genetics have generated a rapid proliferation of primary studies in these fields, leading to the development and application of meta-analytic methods, which have contributed substantially to our understanding o...

  • Article
  • Open Access
38 Citations
15,491 Views
23 Pages

Slow Down: Behavioural and Physiological Effects of Reducing Eating Rate

  • Katherine Hawton,
  • Danielle Ferriday,
  • Peter Rogers,
  • Paula Toner,
  • Jonathan Brooks,
  • Jeffrey Holly,
  • Kalina Biernacka,
  • Julian Hamilton-Shield and
  • Elanor Hinton

27 December 2018

Slowing eating rate appears to be an effective strategy for reducing food intake. This feasibility study investigated the effect of eating rate on post-meal responses using functional magnetic resonance imaging (fMRI), plasma gastrointestinal hormone...

  • Article
  • Open Access
7 Citations
6,022 Views
24 Pages

This study investigated the role of working memory capacity (WMC) in metaphoric and metonymic processing in Mandarin–English bilinguals’ minds. It also explored the neural correlations between metaphor and metonymy computations. We adopte...

  • Article
  • Open Access
2 Citations
3,403 Views
21 Pages

Brain Activity during Visual and Auditory Word Rhyming Tasks in Cantonese–Mandarin–English Trilinguals

  • Yujia Wu,
  • Jingwen Ma,
  • Lei Cai,
  • Zengjian Wang,
  • Miao Fan,
  • Jianping Chu,
  • Yue Zhang and
  • Xiuhong Li

4 December 2020

It is unclear whether the brain activity during phonological processing of second languages (L2) is similar to that of the first language (L1) in trilingual individuals, especially when the L1 is logographic, and the L2s are logographic and alphabeti...

  • Article
  • Open Access
1 Citations
2,618 Views
15 Pages

1 October 2023

This article presents a method for extracting neural signal features to identify the imagination of left- and right-hand grasping movements. A functional magnetic resonance imaging (fMRI) experiment is employed to identify four brain regions with sig...

  • Review
  • Open Access
28 Citations
6,523 Views
33 Pages

15 January 2021

In rodent models the use of functional magnetic resonance imaging (fMRI) under anesthesia is common. The anesthetic protocol might influence fMRI readouts either directly or via changes in physiological parameters. As long as those factors cannot be...

  • Article
  • Open Access
8 Citations
3,627 Views
17 Pages

18 December 2023

Major depressive disorder (MDD) is a prevalent psychiatric condition with a complex and unknown pathological mechanism. Resting-state functional magnetic resonance imaging (rs-fMRI) has emerged as a valuable non-invasive technology for MDD diagnosis....

  • Article
  • Open Access
711 Views
25 Pages

DrSVision: A Machine Learning Tool for Cortical Region-Specific fNIRS Calibration Based on Cadaveric Head MRI

  • Serhat Ilgaz Yöner,
  • Mehmet Emin Aksoy,
  • Hayrettin Can Südor,
  • Kurtuluş İzzetoğlu,
  • Baran Bozkurt and
  • Alp Dinçer

14 October 2025

Functional Near-Infrared Spectroscopy is (fNIRS) a non-invasive neuroimaging technique that monitors cerebral hemodynamic responses by measuring near-infrared (NIR) light absorption caused by changes in oxygenated and deoxygenated hemoglobin concentr...

  • Review
  • Open Access
22 Citations
7,403 Views
13 Pages

Magnetic resonance imaging (MRI) has the potential to serve as a biomarker for Parkinson’s disease (PD). However, the type or types of biomarker it could provide remain to be determined. At this time there is not sufficient sensitivity or specificity...

  • Review
  • Open Access
11 Citations
5,592 Views
13 Pages

Is It Time to Call Time on Bone Marrow Biopsy for Staging Ewing Sarcoma (ES)?

  • Katrina M. Ingley,
  • Simon Wan,
  • Stefan Vöö,
  • Rachael Windsor,
  • Maria Michelagnoli,
  • Asif Saifuddin and
  • Sandra J. Strauss

29 June 2021

Primary malignant bone sarcomas are rare and Ewing sarcoma (ES), along with osteosarcoma, predominates in teenagers and young adults. The well-established multimodality treatment incorporates systemic chemotherapy with local control in the form of su...

  • Article
  • Open Access
2,355 Views
14 Pages

21 October 2022

Sound-induced flash illusion (SiFI) is typical auditory dominance phenomenon in multisensory illusion. Although a number of studies have explored the SiFI in terms of age-related effects, the reasons for the enhanced SiFI in older adults are still co...

  • Review
  • Open Access
64 Citations
20,619 Views
34 Pages

Neurotherapeutics for Attention Deficit/Hyperactivity Disorder (ADHD): A Review

  • Katya Rubia,
  • Samuel Westwood,
  • Pascal-M. Aggensteiner and
  • Daniel Brandeis

21 August 2021

This review focuses on the evidence for neurotherapeutics for attention deficit/hyperactivity disorder (ADHD). EEG-neurofeedback has been tested for about 45 years, with the latest meta-analyses of randomised controlled trials (RCT) showing small/med...

  • Review
  • Open Access
70 Citations
21,583 Views
23 Pages

24 September 2020

The aim of this study was to conduct a comprehensive review on hyperscanning research (measuring brain activity simultaneously from more than two people interacting) using an explicit systematic method, the preferred reporting items for systematic re...

  • Review
  • Open Access
2 Citations
8,780 Views
12 Pages

14 September 2022

One of the central goals of cognitive neuroscience is to understand how structure relates to function. Over the past century, clinical studies on patients with lesions have provided key insights into the relationship between brain areas and behavior....

  • Protocol
  • Open Access
4 Citations
3,913 Views
16 Pages

Protocol Report on the Transcranial Photobiomodulation for Alzheimer’s Disease (TRAP-AD) Study

  • Dan V. Iosifescu,
  • Xiaotong Song,
  • Maia B. Gersten,
  • Arwa Adib,
  • Yoonju Cho,
  • Katherine M. Collins,
  • Kathy F. Yates,
  • Aura M. Hurtado-Puerto,
  • Kayla M. McEachern and
  • Ricardo S. Osorio
  • + 1 author

Background: Alzheimer’s disease’s (AD) prevalence is projected to increase as the population ages and current treatments are minimally effective. Transcranial photobiomodulation (t-PBM) with near-infrared (NIR) light penetrates into the c...

  • Article
  • Open Access
13 Citations
4,233 Views
14 Pages

16 December 2020

N-3 polyunsaturated fatty acid supplements improve the symptoms of major depressive disorder (MDD) in randomized-controlled trials and meta-analyses, with the higher efficacy from anti-inflammatory eicosapentaenoic acid (EPA) than brain-dominant doco...

  • Review
  • Open Access
82 Citations
45,956 Views
20 Pages

Abnormal sensory-based behaviors are a defining feature of autism spectrum disorders (ASD). Dr. A. Jean Ayres was the first occupational therapist to conceptualize Sensory Integration (SI) theories and therapies to address these deficits. Her work wa...

  • Review
  • Open Access
28 Citations
11,905 Views
28 Pages

Recent research has reported motor impairment similarities between children with developmental coordination disorder (DCD) and a subgroup of individuals with autism spectrum disorder (ASD). However, there is a debate as to whether DCD is a co-occurri...

  • Review
  • Open Access
40 Citations
17,831 Views
24 Pages

15 August 2019

Anorexia nervosa (AN) is an eating disorder often occurring in adolescence. AN has one of the highest mortality rates amongst psychiatric illnesses and is associated with medical complications and high risk for psychiatric comorbidities, persisting a...

  • Article
  • Open Access
10 Citations
4,525 Views
15 Pages

Neural Correlates of Impaired Cognitive Control in Individuals with Methamphetamine Dependence: An fMRI Study

  • Ani Zerekidze,
  • Meng Li,
  • Nooshin Javaheripour,
  • Laura Huff,
  • Thomas Weiss,
  • Martin Walter and
  • Gerd Wagner

24 January 2023

Impaired cognitive and behavioral control has often been observed in people who use methamphetamine (MA). However, a comprehensive understanding of the neural substrates underlying these impairments is still lacking. The goal of the present study was...

  • Article
  • Open Access
2 Citations
4,929 Views
16 Pages

26 January 2021

It is now common to apply functional magnetic resonance imaging to explore which areas of the human brain are activated during the decision-making process. In the study of consumer behaviors, product brand has been identified as a major factor affect...

  • Article
  • Open Access
1 Citations
4,450 Views
17 Pages

12 October 2024

Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, and numerous functional and structural differences have been identified in the brains of individuals with ADHD compared to controls. This study uses data from th...

  • Feature Paper
  • Article
  • Open Access
1 Citations
2,511 Views
20 Pages

21 November 2024

Restricted repetitive behaviors (RRB) encompass a variety of inflexible behaviors, which are diagnostic for autism spectrum disorder (ASD). Despite being requisite diagnostic criteria, the neurocircuitry of these behaviors remains poorly understood,...

  • Systematic Review
  • Open Access
13 Citations
10,532 Views
12 Pages

Melodic Intonation Therapy in Post-Stroke Non-Fluent Aphasia and Its Effects on Brain Plasticity

  • Natalia García-Casares,
  • Amanda Barros-Cano and
  • Juan A. García-Arnés

17 June 2022

Melodic Intonation Therapy (MIT) is one of the most well-known therapies for the rehabilitation of speech in patients with non-fluent aphasia and which is thought to promote right-hemisphere involvement in language processing. This review focuses on...

  • Article
  • Open Access
6 Citations
4,107 Views
18 Pages

NRN1 Gene as a Potential Marker of Early-Onset Schizophrenia: Evidence from Genetic and Neuroimaging Approaches

  • Carmen Almodóvar-Payá,
  • Maria Guardiola-Ripoll,
  • Maria Giralt-López,
  • Carme Gallego,
  • Pilar Salgado-Pineda,
  • Salvador Miret,
  • Raymond Salvador,
  • María J. Muñoz,
  • Luisa Lázaro and
  • Amalia Guerrero-Pedraza
  • + 10 authors

Included in the neurotrophins family, the Neuritin 1 gene (NRN1) has emerged as an attractive candidate gene for schizophrenia (SZ) since it has been associated with the risk for the disorder and general cognitive performance. In this work, we aimed...

  • Review
  • Open Access
9,788 Views
13 Pages

Status of Brain Imaging in Gastroparesis

  • Zorisadday Gonzalez and
  • Richard W. McCallum

The pathophysiology of nausea and vomiting in gastroparesis is complicated and multifaceted involving the collaboration of both the peripheral and central nervous systems. Most treatment strategies and studies performed in gastroparesis have focused...

  • Article
  • Open Access
26 Citations
8,563 Views
18 Pages

Probiotic Mixture Containing Lactobacillus helveticus, Bifidobacterium longum and Lactiplantibacillus plantarum Affects Brain Responses to an Arithmetic Stress Task in Healthy Subjects: A Randomised Clinical Trial and Proof-of-Concept Study

  • Hanna M. T. Edebol Carlman,
  • Julia Rode,
  • Julia König,
  • Dirk Repsilber,
  • Ashley N. Hutchinson,
  • Per Thunberg,
  • Jonas Persson,
  • Andrey Kiselev,
  • Jens C. Pruessner and
  • Robert J. Brummer

22 March 2022

Probiotics are suggested to impact physiological and psychological stress responses by acting on the gut-brain axis. We investigated if a probiotic product containing Bifidobacterium longum R0175, Lactobacillus helveticus R0052 and Lactiplantibacillu...

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