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3,838 Results Found

  • Article
  • Open Access
6 Citations
2,173 Views
13 Pages

Safety and Effectiveness of Transvenous Lead Extraction in Patients with Infected Cardiac Resynchronization Therapy Devices; Is It More Risky than Extraction of Other Systems?

  • Paweł Stefańczyk,
  • Dorota Nowosielecka,
  • Anna Polewczyk,
  • Łukasz Tułecki,
  • Konrad Tomków,
  • Wojciech Jacheć,
  • Ewa Lewicka,
  • Andrzej Tomaszewski and
  • Andrzej Kutarski

Background: Transvenous lead extraction (TLE) in patients with implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy (CRT) devices is considered as more risky. The aim of this study was to assess the safety and effectiven...

  • Article
  • Open Access
9 Citations
1,243 Views
12 Pages

1 December 2016

This study aimed to develop an automated model to extract temporal features from DCE-MRI in head-and-neck (HN) cancers to localize significant tumor subvolumes having low blood volume (LBV) for predicting local and regional failure after chemoradiati...

  • Article
  • Open Access
1 Citations
2,046 Views
18 Pages

Post-Extraction Bone Changes in Molars Within Personalized Implant-Prosthetic Therapy as Evaluated with Fractal Analysis of CBCT

  • Antonia Samia Khaddour,
  • Sanda Mihaela Popescu,
  • Mihaela Ionescu,
  • Alex Ioan Sălan,
  • Răzvan Eugen Ghiţă,
  • Melania Olimpia Cojocaru,
  • Iulia Roxana Marinescu,
  • Marina Olimpia Amărăscu and
  • Emma Cristina Draghici

16 April 2025

Background: Implant-prosthetic therapy requires a detailed assessment of the bone structure before designing a personalized treatment plan. Tooth extraction at the molar level is followed by a series of bone changes dependent on the patient’s g...

  • Case Report
  • Open Access
3 Citations
5,028 Views
14 Pages

15 January 2022

Hyperbaric Oxygen Therapy (HBOT) is a stress-free, relatively safe method supporting the treatment of many different diseases. Although it is widely used in human medicine (including dentistry), in veterinary medicine, especially in the treatment of...

  • Review
  • Open Access
25 Citations
8,224 Views
16 Pages

18 September 2020

High-intensity laser therapy (HILT) and photobiomodulation therapy (PBMT) are two types of laser treatment. According to recent clinical reports, PBMT promotes wound healing after trauma or surgery. In addition, basic research has revealed that cell...

  • Systematic Review
  • Open Access
15 Citations
2,846 Views
19 Pages

The Effectiveness and Safety of Autologous Platelet Concentrates as Hemostatic Agents after Tooth Extraction in Patients on Anticoagulant Therapy: A Systematic Review of Randomized, Controlled Trials

  • Maria Domenica Campana,
  • Angelo Aliberti,
  • Alfonso Acerra,
  • Pasquale Sammartino,
  • Pasquale Dolce,
  • Gilberto Sammartino and
  • Roberta Gasparro

17 August 2023

One of the common challenges in oral surgery is dealing with patients who are taking oral anticoagulant/antiaggregant drugs. Several local hemostatic agents have been proposed as an alternative to conventional suturing. Among these, autologous platel...

  • Article
  • Open Access
1 Citations
953 Views
16 Pages

The Effect of Antimicrobial Photodynamic Therapy on the Healing of the Post-Extraction Socket of the Mandibular Third Molar: A Randomized Clinical Study

  • Alessia Pardo,
  • Maria Lonardi,
  • Annarita Signoriello,
  • Gianluca Colapinto,
  • Funda Goker,
  • Margherita Tumedei,
  • Massimo Albanese and
  • Massimo Del Fabbro

16 July 2025

Objectives: We aimed to evaluate the efficacy of antimicrobial photodynamic therapy (aPDT) in promoting wound healing after the surgical removal of inferior third molars. Methods: Patients in need of unilateral mandibular third molar extraction were...

  • Review
  • Open Access
13 Citations
4,474 Views
29 Pages

14 February 2023

Radiotherapy is a standard treatment for head and neck cancer patients worldwide. However, millions of patients who received radiotherapy consequently suffer from xerostomia because of irreversible damage to salivary glands (SGs) caused by irradiatio...

  • Article
  • Open Access
2 Citations
2,342 Views
24 Pages

10 June 2024

Cancer therapy, from malignant tumor inhibition to cellular eradication treatment, remains a challenge, especially regarding reduced side effects and low energy consumption during treatment. Hence, phytochemicals as cytotoxic sensitizers or photosens...

  • Article
  • Open Access
161 Views
16 Pages

Characterization of the Extraction System of Supersonic Gas Curtain-Based Ionization Profile Monitor for FLASH Proton Therapy

  • Farhana Thesni Mada Parambil,
  • Milaan Patel,
  • Narender Kumar,
  • Bharat Singh Rawat,
  • William Butcher,
  • Tony Price and
  • Carsten P. Welsch

FLASH radiotherapy requires real-time, non-invasive beam monitoring systems capable of operating under ultra-high dose rate (UHDR) conditions without perturbing the therapeutic beam. In this work, we characterized the extraction system of Supersonic...

  • Systematic Review
  • Open Access
10 Citations
5,639 Views
24 Pages

Acceleration Techniques for Teeth Movements in Extractive Orthodontic Therapy

  • Gianna Dipalma,
  • Assunta Patano,
  • Irene Ferrara,
  • Fabio Viapiano,
  • Anna Netti,
  • Sabino Ceci,
  • Daniela Azzollini,
  • Anna Maria Ciocia,
  • Giuseppina Malcangi and
  • Angelo Michele Inchingolo
  • + 3 authors

29 August 2023

For a world that is constantly trying to speed up every procedure while obtaining the maximum result, traditional orthodontics have the biological limitation of using light and constant forces that allow tooth movement in a time frame that is only so...

  • Review
  • Open Access
9 Citations
4,054 Views
11 Pages

2 December 2022

The hexanic extract of Serenoa repens (HESr) has been in use for decades as an effective, safe and well-tolerated therapy for relieving bothersome lower urinary tract symptoms (LUTS) associated with benign prostate hyperplasia (BPH). This manuscript...

  • Article
  • Open Access
11 Citations
3,381 Views
15 Pages

25 November 2021

Antibiotic therapy and photodynamic therapy (PDT) are commonly used to treat bacterial infections. Unfortunately, these methods are often ineffective. Therefore, agents that could effectively support antibiotic therapy and PDT in the inactivation of...

  • Article
  • Open Access
54 Citations
6,403 Views
21 Pages

25 September 2019

Sjogren’s syndrome (SS) is an autoimmune disease that manifests primarily in salivary and lacrimal glands leading to dry mouth and eyes. Unfortunately, there is no cure for SS due to its complex etiopathogenesis. Mesenchymal stem cells (MSCs) were su...

  • Article
  • Open Access
6 Citations
2,433 Views
12 Pages

Evaluation of the Hemostatic Effect of an Innovative Tissue Adhesive during Extraction Therapy under Rivaroxaban in a Rodent Model

  • Marius Heitzer,
  • Philipp Winnand,
  • Anna Bock,
  • Mark Ooms,
  • Marie Sophie Katz,
  • Kristian Kniha,
  • Oliver Grottke,
  • Frank Hölzle and
  • Ali Modabber

An increase in rivaroxaban therapies is associated with increased numbers of postoperative bleeding despite the use of hemostatic sponges, which are currently the gold standard treatment. VIVO has shown promising hemostatic results, favorable tissue...

  • Article
  • Open Access
4 Citations
2,019 Views
11 Pages

Influence of the Antithrombotic Therapy in the Healing of Simple Post-Extraction Sockets: A Randomized Clinical Trial

  • Gilberto Sammartino,
  • Roberta Gasparro,
  • Gianrico Spagnuolo,
  • Alessandra Miniello,
  • Andrea Blasi and
  • Gaetano Marenzi

24 June 2022

Background: An adequate blood supply plays a leading role in the healing process of the post-extractive socket; its coagulation leads to fibrin clot formation, which acts as a physical barrier able to prevent postoperative bleeding and microbial infe...

  • Article
  • Open Access
1,690 Views
14 Pages

The Impact of Damon Self-Ligating Orthodontic Therapy on Soft Tissue and Incisor Inclination: Extraction vs. Non-Extraction Treatment

  • Sarah Bühling,
  • Sabrina Schmied,
  • Sara Eslami,
  • Silvia Brandt,
  • Nicolas Plein,
  • Stefan Kopp and
  • Babak Sayahpour

22 August 2025

(1) Background: The present study aimed to evaluate the effects of fixed orthodontic treatment using the Damon self-ligating system on incisor inclination and soft tissue facial profile. Additionally, the study compared the outcomes of premolar extra...

  • Article
  • Open Access
6 Citations
4,642 Views
14 Pages

Evaluation of Preventive Treatment Protocols for Patients under Antiresorptive Therapy Undergoing Tooth Extraction at a Swiss University Clinic

  • Ellen Pick,
  • Nicolas Leuenberger,
  • Irina Kuster,
  • Nicole Selina Stutzmann,
  • Bernd Stadlinger and
  • Silvio Valdec

Antiresorptive agent-related osteonecrosis of the jaw (ARONJ) is a dreaded complication in patients with compromised bone metabolism. The purpose of the present study was to examine the occurrence of ARONJ and its related factors among patients with...

  • Article
  • Open Access
323 Views
16 Pages

Dual-Wavelength 980 nm and 1550 nm Laser Therapy Accelerates Alveolar Socket Healing After Tooth Extraction

  • Dinislam Davletshin,
  • Aglaya Kazumova,
  • Alexey Fayzullin,
  • Nune Vartanova,
  • Peter Timashev,
  • Andronik Poddubikov,
  • Svetlana Tarasenko,
  • Pavel Kryuchko,
  • Ivan Klenkov and
  • Ekaterina Diachkova
  • + 3 authors

1 January 2026

Background/Objectives: Alveolitis, or “dry socket,” is a common complication after tooth extraction, associated with pain, inflammation and delayed healing. Standard surgical treatments are often invasive and insufficient. Laser therapy o...

  • Review
  • Open Access
21 Citations
6,048 Views
37 Pages

A Systematic Review on Feature Extraction in Electroencephalography-Based Diagnostics and Therapy in Attention Deficit Hyperactivity Disorder

  • Pasquale Arpaia,
  • Attilio Covino,
  • Loredana Cristaldi,
  • Mirco Frosolone,
  • Ludovica Gargiulo,
  • Francesca Mancino,
  • Federico Mantile and
  • Nicola Moccaldi

29 June 2022

A systematic review on electroencephalographic (EEG)-based feature extraction strategies to diagnosis and therapy of attention deficit hyperactivity disorder (ADHD) in children is presented. The analysis is realized at an executive function level to...

  • Article
  • Open Access
4 Citations
3,672 Views
10 Pages

Effectiveness of Auditory Distraction and Brief Relaxation Therapy in Reducing Anxiety in Dental Patients Undergoing Extraction: A Randomized Controlled Trial

  • Yaser Ali Alhazmi,
  • Amal Mohammed Mobarki,
  • Wala’a Haser Hakami,
  • Hanin Naser Akairi,
  • Yusra Khalid Altherwi and
  • Mir Faeq Ali Quadri

2 January 2022

Objective: This study compared the effectiveness of auditory distraction and brief relaxation therapy for reducing anxiety in patients undergoing tooth extraction. Methods: A non-blind, three-armed, randomized control trial was carried out. The targe...

  • Case Report
  • Open Access
7 Citations
7,544 Views
8 Pages

Tooth extraction in patients treated with bisphosphonates (BPs) for osteoporosis or cancer exposes the patient to the risk of osteonecrosis of the jaw. An autologous membrane using platelet-rich fibrin (PRF) is an innovative technique to promote woun...

  • Review
  • Open Access
9 Citations
9,968 Views
14 Pages

31 October 2022

The occurrence of bleeding following dental extraction is a relatively common complication. A history of therapy with oral anticoagulants represents a major favoring factor, both in patients treated with vitamin K-antagonists (especially warfarin) an...

  • Tutorial
  • Open Access
2 Citations
323 Views
13 Pages

This article addresses selected concepts and procedures related to orofacial myology in a question and answer format. Topics include tongue-tip placement for swallowing; a massetercontraction swallow; temporary anchorage devices utilized in orthodont...

  • Systematic Review
  • Open Access
14 Citations
10,977 Views
20 Pages

Effectiveness of Herbal Medicines with Anti-Inflammatory, Antimicrobial, and Antioxidant Properties in Improving Oral Health and Treating Gingivitis and Periodontitis: A Systematic Review

  • Giuseppina Malcangi,
  • Angelo Michele Inchingolo,
  • Lucia Casamassima,
  • Irma Trilli,
  • Laura Ferrante,
  • Francesco Inchingolo,
  • Andrea Palermo,
  • Alessio Danilo Inchingolo and
  • Gianna Dipalma

21 February 2025

Objectives: This systematic review investigates the effectiveness of natural extracts with anti-inflammatory properties for improving oral health, particularly in managing gingivitis and periodontal disease (PD). With PD being a major global health i...

  • Article
  • Open Access
6 Citations
2,586 Views
12 Pages

Metronidazole and Vancomycin Have a Synergic Effect, with Plant Extracts as Helpful Tools to Combat Clostridioides difficile Infections

  • Nancy C. Ruiz-Pérez,
  • Yuli Bayona-Pérez,
  • Silvia Laura Guzmán-Gutiérrez,
  • Ricardo Reyes-Chilpa,
  • Víctor M. Luna-Pineda,
  • Javier Torres and
  • Mariana Romo-Castillo

Background/Objectives: The prolonged use of antibiotics is closely related to increased infections caused by Clostridioides difficile (Cdiff). Plant-origin compounds have been expanding in recent years as the best opportunity to identify new synergic...

  • Article
  • Open Access
23 Citations
5,819 Views
14 Pages

Photobiomodulation Therapy on Orthodontic Movement: Analysis of Preliminary Studies with a New Protocol

  • Alessandra Impellizzeri,
  • Martina Horodynski,
  • Riccardo Fusco,
  • Gaspare Palaia,
  • Antonella Polimeni,
  • Umberto Romeo,
  • Ersilia Barbato and
  • Gabriella Galluccio

This study aimed to investigate the effectiveness of photobiomodulation therapy (PBMT) on the acceleration of orthodontic movements, deriving from its biostimulating and regenerative capacity on soft tissues, consequent to the increase in differentia...

  • Review
  • Open Access
3 Citations
10,693 Views
22 Pages

Combined Potential of Orlistat with Natural Sources and Their Bioactive Compounds Against Obesity: A Review

  • Jonatan Jafet Uuh Narvaez,
  • Ivan Chan Zapata and
  • Maira Rubi Segura Campos

Obesity represents a significant global public health issue, contributing to the rising prevalence of metabolic diseases. One treatment for obesity is orlistat, a drug that inhibits pancreatic lipase. It is widely used due to its efficacy in reducing...

  • Article
  • Open Access
5 Citations
3,740 Views
14 Pages

Evaluation of the Potential Beneficial Effects of Ferula communis L. Extract Supplementation in Postmenopausal Discomfort

  • Roberta Macrì,
  • Jessica Maiuolo,
  • Federica Scarano,
  • Vincenzo Musolino,
  • Annalisa Fregola,
  • Micaela Gliozzi,
  • Cristina Carresi,
  • Saverio Nucera,
  • Maria Serra and
  • Vincenzo Mollace
  • + 9 authors

11 August 2024

Peri-menopausal discomfort can have a detrimental effect on the physical health of women due to physiological and behavioral changes. Estrogen and progesterone-based hormone therapy can alleviate menopausal symptoms, but estrogen supplementation may...

  • Review
  • Open Access
18 Citations
18,099 Views
15 Pages

Vegetable Extracts and Nutrients Useful in the Recovery from Helicobacter pylori Infection: A Systematic Review on Clinical Trials

  • Hammad Ullah,
  • Alessandro Di Minno,
  • Cristina Santarcangelo,
  • Haroon Khan,
  • Jianbo Xiao,
  • Carla Renata Arciola and
  • Maria Daglia

14 April 2021

Helicobacter pylori (H. pylori) infections affect almost half of the world’s population, with gradually increasing incidence in developed countries. Eradication of H. pylori may provide significant benefits to the affected individual by healing a num...

  • Review
  • Open Access
280 Views
16 Pages

15 January 2026

Background: Intentional tooth replantation (ITR) is a promising treatment option for preserving teeth in cases where conventional endodontic therapy is challenging, or when previous endodontic treatment and apicoectomy have been unsuccessful. The pro...

  • Review
  • Open Access
99 Citations
15,056 Views
89 Pages

Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation

  • Wamidh H. Talib,
  • Izzeddin Alsalahat,
  • Safa Daoud,
  • Reem Fawaz Abutayeh and
  • Asma Ismail Mahmod

14 November 2020

Cancer is one of the main causes of death globally and considered as a major challenge for the public health system. The high toxicity and the lack of selectivity of conventional anticancer therapies make the search for alternative treatments a prior...

  • Article
  • Open Access
1 Citations
1,279 Views
29 Pages

30 June 2025

This study investigates near-infrared (NIR)-induced, Phyto-enhanced, second harmonic generation-mediated photodynamic therapy (Phyto-SHG-PDT) using barium titanate (BT)/rhein/polyethylene glycol 100 (PEG100) and BT/Yemenite “Etrog” leaf e...

  • Article
  • Open Access
3 Citations
1,961 Views
16 Pages

Complex Hippocampal Response to Thermal Skin Injury and Protocols with Hyperbaric Oxygen Therapy and Filipendula ulmaria Extract in Rats

  • Bojana Krstic,
  • Dragica Selakovic,
  • Nemanja Jovicic,
  • Milos Krstic,
  • Jelena S. Katanic Stankovic,
  • Sara Rosic,
  • Dragan Milovanovic and
  • Gvozden Rosic

The aim of this study was to evaluate the alterations of the hippocampal function that may be related to anxiogenic response to thermal skin injury, including the morpho-functional alterations, and the effects of hyperbaric oxygen (HBO) and Filipendu...

  • Systematic Review
  • Open Access
10 Citations
7,390 Views
24 Pages

14 March 2024

Chemoresistance is a challenge in cancer treatment, limiting the effectiveness of chemotherapy. Mushroom extracts have shown potential as treatments for cancer therapies, offering a possible solution to overcome chemoresistance. This systematic revie...

  • Article
  • Open Access
8 Citations
5,462 Views
13 Pages

Eruption Pattern of Third Molars in Orthodontic Patients Treated with First Permanent Molar Extraction: A Longitudinal Retrospective Evaluation

  • Lisa J. Langer,
  • Nikolaos Pandis,
  • Maria R. Mang de la Rosa,
  • Paul-Georg Jost-Brinkmann and
  • Theodosia N. Bartzela

30 January 2023

The aim of this study was to evaluate angular and positional changes in the second (M2) and third molars (M3) of orthodontically treated patients undergoing a first molar (M1) extraction. A retrospective longitudinal study with a sample of 152 pre- a...

  • Brief Report
  • Open Access
1 Citations
996 Views
10 Pages

Oral Cannabidiol for Acute Post-Extraction Pain: A Randomized Pilot Study

  • Ammaar H. Abidi,
  • Modar Kassan and
  • Karen Derefinko

25 November 2025

Introduction/Objective: Dental extractions are among the most common oral surgical procedures worldwide, with postoperative pain representing a significant clinical concern. Cannabidiol (CBD), a non-intoxicating phytocannabinoid with analgesic and an...

  • Article
  • Open Access
308 Views
20 Pages

Comparative Fractal Analysis on Orthopantomography Images of Bone Remodeling Changes at 3 Months Between Natural Socket Healing and Immediate Implant Placement

  • Andrei Radu,
  • Mihaela Ionescu,
  • Antonia Samia Khaddour,
  • Cristina Maria Munteanu,
  • Monica Mihaela Iacov Crăițoiu,
  • Melania Olimpia Cojocaru,
  • Alex Ioan Sălan,
  • Iulia Roxana Marinescu,
  • Răzvan Mercuț and
  • Sanda Mihaela Popescu

Background: Osseointegration is the main factor that ensures the long-term success of implant-prosthetic therapy, but besides this, there are other important factors, such as the quality of the alveolar bone and the time of placement of dental implan...

  • Article
  • Open Access
17 Citations
7,144 Views
12 Pages

Patient Experiences and Perceptions Associated with the Use of Desiccated Thyroid Extract

  • Freddy J. K. Toloza,
  • Nataly R. Espinoza Suarez,
  • Omar El Kawkgi,
  • Elizabeth H. Golembiewski,
  • Oscar J. Ponce,
  • Lixia Yao,
  • Spyridoula Maraka,
  • Naykky M. Singh Ospina and
  • Juan P. Brito

3 April 2020

Background and objectives: It is unclear why many patients with hypothyroidism prefer the use of desiccated thyroid extract (DTE) as a thyroid hormone replacement formulation over levothyroxine (LT4) treatment, as recommended by clinical practice gui...

  • Article
  • Open Access
1,481 Views
14 Pages

Laser-Mediated Hemostasis for Older Patients Receiving Routine Dental Treatment

  • Suwat Tanya,
  • Saengsome Prajaneh,
  • Piyachat Patcharanuchat and
  • Sajee Sattayut

11 July 2025

Background/Objective: Laser therapy has gained attention in dental practice to minimize bleeding and enhance blood clot formation. This study aimed to explore the utilization and to compare the clinical efficacy of laser-mediated hemostasis for older...

  • Article
  • Open Access
3 Citations
2,372 Views
14 Pages

15 November 2024

Popular photoluminescent (PL) nanomaterials, such as carbon dots, have attracted substantial attention from scientists due to their photophysical properties, biocompatibility, low cost, and diverse applicability. Carbon dots have been used in sensors...

  • Article
  • Open Access
4 Citations
2,264 Views
19 Pages

In Situ Aqueous Spice Extract-Based Antifungal Lock Strategy for Salvage of Foley’s Catheter Biofouled with Candida albicans Biofilm Gel

  • Bindu Sadanandan,
  • Vaniyamparambath Vijayalakshmi,
  • Kalidas Shetty,
  • Adithya Rathish,
  • Harshala Shivkumar,
  • Malavika Gundreddy,
  • Nikhil Kumar Kagganti Narendra and
  • Nethra Machamada Devaiah

1 January 2025

Candida forms a gel-like biofilm in the Foley’s catheter (FC) causing tenacious biofouling and severe urinary tract infections (UTIs). For the first time, a spice extract-based antifungal lock therapy (ALT) has been developed to inhibit the Can...

  • Article
  • Open Access
20 Citations
4,512 Views
17 Pages

Pigmentation Levels Affect Melanoma Responses to Coriolus versicolor Extract and Play a Crucial Role in Melanoma-Mononuclear Cell Crosstalk

  • Małgorzata Pawlikowska,
  • Tomasz Jędrzejewski,
  • Andrzej T. Slominski,
  • Anna A. Brożyna and
  • Sylwia Wrotek

Melanoma, the malignancy originating from pigment-producing melanocytes, is the most aggressive form of skin cancer and has a poor prognosis once the disease starts to metastasize. The process of melanin synthesis generates an immunosuppressive and m...

  • Review
  • Open Access
193 Citations
17,941 Views
30 Pages

Health problems and reduced treatment effectiveness due to antimicrobial resistance have become important global problems and are important factors that negatively affect life expectancy. Antimicrobial photodynamic therapy (APDT) is constantly evolvi...

  • Review
  • Open Access
7 Citations
4,043 Views
15 Pages

Natural products have historically played an important role as a source of therapeutic drugs for various diseases, and the development of medicinal natural products is still a field with high potential. Although diverse drugs have been developed for...

  • Article
  • Open Access
21 Citations
5,329 Views
17 Pages

Management of Acute Radiodermatitis in Non-Melanoma Skin Cancer Patients Using Electrospun Nanofibrous Patches Loaded with Pinus halepensis Bark Extract

  • Aikaterini Kyritsi,
  • Stefanos Kikionis,
  • Anna Tagka,
  • Nikolaos Koliarakis,
  • Antonia Evangelatou,
  • Panagiotis Papagiannis,
  • Alexandros Stratigos,
  • Vangelis Karalis,
  • Paraskevas Dallas and
  • Michail Rallis
  • + 3 authors

26 May 2021

Acute radiodermatitis is the most common side effect in non-melanoma skin cancer patients undergoing radiotherapy. Nonetheless, despite the ongoing progress of clinical trials, no effective regimen has been found yet. In this study, a non-woven patch...

  • Article
  • Open Access
2 Citations
2,225 Views
10 Pages

Porcine Placental Extract Improves the Lipid Profile and Body Weight in a Post-Menopausal Rat Model Without Affecting Reproductive Tissues

  • Tugsjargal Purevdorj,
  • Moeka Arata,
  • Mari Nii,
  • Shota Yamamoto,
  • Hiroki Noguchi,
  • Asuka Takeda,
  • Hidenori Aoki,
  • Hiroaki Inui,
  • Tomohiro Kagawa and
  • Takeshi Iwasa
  • + 3 authors

11 March 2025

Introduction: What if porcine placental extract (PPE) could combat post-menopausal weight gain and lipid imbalances without the side effects of traditional hormone treatments? The menopause marks a critical shift in women’s health, with declini...

  • Review
  • Open Access
29 Citations
6,265 Views
25 Pages

Phytochemicals Involved in Mitigating Silent Toxicity Induced by Heavy Metals

  • Jessica Ceramella,
  • Azzurra Chiara De Maio,
  • Giovanna Basile,
  • Anastasia Facente,
  • Elisabetta Scali,
  • Inmaculada Andreu,
  • Maria Stefania Sinicropi,
  • Domenico Iacopetta and
  • Alessia Catalano

22 March 2024

Heavy metals (HMs) are natural elements present in the Earth’s crust, characterised by a high atomic mass and a density more than five times higher than water. Despite their origin from natural sources, extensive usage and processing of raw mat...

  • Systematic Review
  • Open Access
17 Citations
12,875 Views
36 Pages

Herbal Medicines for the Treatment of Active Ulcerative Colitis: A Systematic Review and Meta-Analysis

  • Preetha Iyengar,
  • Gala Godoy-Brewer,
  • Isha Maniyar,
  • Jacob White,
  • Laura Maas,
  • Alyssa M. Parian and
  • Berkeley Limketkai

23 March 2024

Herbal medicines are used by patients with IBD despite limited evidence. We present a systematic review and meta-analysis of randomized controlled trials (RCTs) investigating treatment with herbal medicines in active ulcerative colitis (UC). A search...

  • Article
  • Open Access
10 Citations
4,140 Views
19 Pages

Practical Assessment of an Interdisciplinary Bacteriophage Delivery Pipeline for Personalized Therapy of Gram-Negative Bacterial Infections

  • Silvia Würstle,
  • Jana Stender,
  • Jens André Hammerl,
  • Kilian Vogele,
  • Kathrin Rothe,
  • Christian Willy and
  • Joachim Jakob Bugert

2 February 2022

Despite numerous advances in personalized phage therapy, smooth logistics are challenging, particularly for multidrug-resistant Gram-negative bacterial infections requiring high numbers of specific lytic phages. We conducted this study to pave the wa...

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