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Review

Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation

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Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman 11931, Jordan
2
Department of Pharmaceutical Chemistry and Pharmacognosy, Applied Science Private University, Amman 11931, Jordan
*
Author to whom correspondence should be addressed.
Academic Editors: Teresa Mencherini and Francesca Sansone
Molecules 2020, 25(22), 5319; https://doi.org/10.3390/molecules25225319
Received: 10 October 2020 / Revised: 10 November 2020 / Accepted: 11 November 2020 / Published: 14 November 2020
Cancer is one of the main causes of death globally and considered as a major challenge for the public health system. The high toxicity and the lack of selectivity of conventional anticancer therapies make the search for alternative treatments a priority. In this review, we describe the main plant-derived natural products used as anticancer agents. Natural sources, extraction methods, anticancer mechanisms, clinical studies, and pharmaceutical formulation are discussed in this review. Studies covered by this review should provide a solid foundation for researchers and physicians to enhance basic and clinical research on developing alternative anticancer therapies. View Full-Text
Keywords: alternative anticancer therapies; natural products; plant extracts; curcumin; thymoquinon alternative anticancer therapies; natural products; plant extracts; curcumin; thymoquinon
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MDPI and ACS Style

Talib, W.H.; Alsalahat, I.; Daoud, S.; Abutayeh, R.F.; Mahmod, A.I. Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation. Molecules 2020, 25, 5319. https://doi.org/10.3390/molecules25225319

AMA Style

Talib WH, Alsalahat I, Daoud S, Abutayeh RF, Mahmod AI. Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation. Molecules. 2020; 25(22):5319. https://doi.org/10.3390/molecules25225319

Chicago/Turabian Style

Talib, Wamidh H., Izzeddin Alsalahat, Safa Daoud, Reem F. Abutayeh, and Asma I. Mahmod. 2020. "Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation" Molecules 25, no. 22: 5319. https://doi.org/10.3390/molecules25225319

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