Skip to Content

63 Results Found

  • Article
  • Open Access
658 Views
13 Pages

Factors Associated with Autopsy Consent in Pediatric Oncology: A 10-Year Review

  • Meaghann S. Weaver,
  • Jia Liang,
  • Rachel Jalfon,
  • Yimei Li,
  • Abagail D. Cohen and
  • Liza-Marie Johnson

Purpose: Autopsy remains an important diagnostic and research modality in pediatric oncology. This study examined demographic and clinical factors associated with parental acceptance or decline of autopsy in childhood cancer. Patients and Methods: Th...

(This article belongs to the Section Childhood, Adolescent and Young Adult Oncology)
  • Article
  • Open Access
14 Citations
3,402 Views
7 Pages

Association between Toxoplasma gondii Infection in Brain and a History of Depression in Suicide Decedents: A Cross-Sectional Study

  • Cosme Alvarado-Esquivel,
  • Laura Alejandra Mendoza-Larios,
  • Fernando García-Dolores,
  • Luis Francisco Sánchez-Anguiano,
  • Elizabeth Irasema Antuna-Salcido,
  • Jesús Hernández-Tinoco,
  • Adriana Rocha-Salais,
  • Marcela Araceli Segoviano-Mendoza and
  • Antonio Sifuentes-Álvarez

13 October 2021

We assessed the association between Toxoplasma gondii (T. gondii) infection of the central nervous system and suicide correlates in suicide decedents. Eighty-seven decedents who died by suicide received in a forensic setting for medico-legal autopsie...

(This article belongs to the Special Issue Effects of Toxoplasma gondii Infection on Human Behaviour)
  • Article
  • Open Access
1 Citations
1,977 Views
9 Pages

Evidence shows that older patients with advance directives such as a living will, or durable power of attorney for healthcare, are more likely to receive care consistent with their preferences at the end of life. Less is known about the use of advanc...

(This article belongs to the Special Issue Health and Social Care Policy)
  • Article
  • Open Access
9 Citations
6,086 Views
13 Pages

Psychiatric and Psychosocial Factors of Suicide Decedents and Survivor of Suicide Loss: Psychological Autopsy Study of Incheon City in South Korea

  • Mi-Nam Bae,
  • Seo-Eun Cho,
  • Ju-Hyeon Ryu,
  • Mi-Hwa Kim,
  • Hye-Jin Jeon,
  • Eun-Ji Shin,
  • Seon-A Lee,
  • Tae-Yeon Hwang and
  • Seung-Gul Kang

In South Korea, the suicide rate is more than double the OECD average, and precise identification of the cause is required for suicide prevention. Psychological autopsy is used to reveal factors related to suicidal behavior; however, such studies are...

(This article belongs to the Special Issue Suicide Prevention: A Public Health Imperative)
  • Article
  • Open Access
1,228 Views
18 Pages

Measuring Narrative Complexity Among Suicide Deaths in the National Violent Death Reporting System (2003–2021 NVDRS)

  • Christina Chance,
  • Alina Arseniev-Koehler,
  • Vickie M. Mays,
  • Kai-Wei Chang and
  • Susan D. Cochran

15 November 2025

A widely used repository of violent death records is the U.S. Centers for Disease Control National Violent Death Reporting System (NVDRS). The NVDRS includes narrative data, which researchers frequently utilize to go beyond its structured variables....

(This article belongs to the Special Issue Natural Language Processing (NLP) with Applications and Natural Language Understanding (NLU), 2nd Edition)
  • Article
  • Open Access
5 Citations
3,678 Views
11 Pages

Clinical Relevance of Unexpected Findings of Post-Mortem Computed Tomography in Hospitalized Patients: An Observational Study

  • Max G. Mentink,
  • Bartholomeus G. H. Latten,
  • Frans C. H. Bakers,
  • Casper Mihl,
  • Roger J. M. W. Rennenberg,
  • Bela Kubat and
  • Paul A. M. Hofman

Background and objective: The current literature describing the use of minimally invasive autopsy in clinical care is mainly focused on the cause of death. However, the identification of unexpected findings is equally important for the evaluation and...

(This article belongs to the Special Issue Forensic Epidemiology)
  • Communication
  • Open Access
5 Citations
2,036 Views
8 Pages

Affecting Factors of Prostate Volume in Forensic Autopsied Decedents

  • Kota Tanaka,
  • Masahito Hitosugi,
  • Marin Takaso,
  • Mami Nakamura and
  • Arisa Takeda

Because decedents undergoing forensic autopsies would have behaved normally before death, prostate volume according to age group can be confirmed with forensic autopsy materials. The objectives of this study were to first confirm the current prostate...

(This article belongs to the Special Issue Innovations in Forensic Medicine)
  • Article
  • Open Access
1 Citations
3,137 Views
14 Pages

Identifying Witnessed Suicides in National Violent Death Reporting System Narratives

  • Vickie M. Mays,
  • Mikaela Gareeb,
  • Xingruo Zhang,
  • Vivian Nguyen,
  • Joelle Rosenberg,
  • Yuri Lin,
  • Alina Arseniev-Koehler,
  • Adam Eliav,
  • Jacob Gates Foster and
  • Susan D. Cochran
  • + 1 author

15 January 2024

There is increasing attention to suicides that occur in view of others, as these deaths can cause significant psychological impact on witnesses. This study illuminates characteristics of witnessed suicides and compares characteristics of these deaths...

  • Article
  • Open Access
8 Citations
3,287 Views
12 Pages

Background: Systemic sclerosis (SSc) has the highest mortality rate among autoimmune disorders. Individuals with SSc frequently die from complications or infections related to SSc. Nonetheless, the sex–age–period interaction of SSc is com...

(This article belongs to the Section Public Health Statistics and Risk Assessment)
  • Article
  • Open Access
28 Citations
4,782 Views
11 Pages

Trajectory of End-of-Life Pain and Other Physical Symptoms among Cancer Patients Receiving Home Care

  • Hsien Seow,
  • Dawn M. Guthrie,
  • Tara Stevens,
  • Lisa C. Barbera,
  • Fred Burge,
  • Kimberlyn McGrail,
  • Kelvin K. W. Chan,
  • Stuart J. Peacock and
  • Rinku Sutradhar

28 April 2021

Purpose: To describe the trajectory of physical symptoms among cancer decedents who were receiving home care in the six months before death. Patients and Methods: An observational cohort study of cancer decedents in Ontario, Canada, who received home...

  • Article
  • Open Access
37 Citations
11,759 Views
17 Pages

Adolescents’ exposure to a peer’s suicide has been found to be associated with, as well as to predict, suicidal ideation and behavior. Although postvention efforts tend to be school-based, little is known about the impact of a schoolmate’s suicide on...

(This article belongs to the Special Issue Advances in Suicide Research)
  • Article
  • Open Access
5 Citations
3,022 Views
18 Pages

Trace and Major Element Concentrations in Cadaveric Lung Tissues from World Trade Center Health Registry Decedents and Community Controls

  • Michael Marmor,
  • Joyce L. Burcham,
  • Lung-Chi Chen,
  • Steven N. Chillrud,
  • Jason K. Graham,
  • Hannah T. Jordan,
  • Mianhua Zhong,
  • Elizabeth Halzack,
  • James E. Cone and
  • Yongzhao Shao

Studies of the health impacts of the 11 September 2001 terrorist attacks on New York City’s (NYC’s) World Trade Center (WTC) towers have been hindered by imprecise estimates of exposure. We sought to identify potential biomarkers of WTC e...

  • Article
  • Open Access
4 Citations
1,498 Views
9 Pages

Comparing Enrolees with Non-Enrolees of Cancer-Patient Navigation at End of Life

  • G. Park,
  • G.M. Johnston,
  • R. Urquhart,
  • G. Walsh and
  • M. McCallum

1 June 2018

Background: Cancer-patient navigators who are oncology nurses support and connect patients to resources throughout the cancer care trajectory, including end of life. Although qualitative and cohort studies of navigated patients have been reported, no...

  • Article
  • Open Access
1 Citations
2,629 Views
16 Pages

Fine particulate matter (PM2.5) has been associated with mortality at low concentrations, with higher per-unit risk at lower exposure levels, and no threshold of effect. We examined characteristics of Medicare decedents living in zip codes at the low...

  • Article
  • Open Access
8 Citations
3,038 Views
11 Pages

Still’s Disease Mortality Trends in France, 1979–2016: A Multiple-Cause-of-Death Study

  • Caroline Borciuch,
  • Mathieu Fauvernier,
  • Mathieu Gerfaud-Valentin,
  • Pascal Sève and
  • Yvan Jamilloux

30 September 2021

Still’s disease (SD) is often considered a benign disease, with low mortality rates. However, few studies have investigated SD mortality and its causes and most of these have been single-center cohort studies. We sought to examine mortality rates and...

(This article belongs to the Special Issue Advances in Adult-Onset Still’s Disease and Systemic Juvenile Idiopathic Arthritis)
  • Article
  • Open Access
3 Citations
1,442 Views
9 Pages

Clinical and Pathological Findings of Fatal 2009–2010 Pandemic Influenza A (H1N1) Infection in Estonia

  • Kadri Tamme,
  • Ave Minajeva,
  • Vivika Adamson,
  • Kaarina Ristmägi,
  • Jaak Põder and
  • Irja Lutsar

4 February 2012

The aim of this study was to analyze all deaths from A (H1N1) in Estonia during the 2009–2010 epidemic to find out the reasons of high mortality and optimize management strategies for future influenza epidemics.

Material and Methods
. A retrospective...

  • Case Report
  • Open Access
8,694 Views
13 Pages

Following a recent death, a human skull was found in a worn physician bag at the decedent’s residence. The bag was labeled with the name “G.B. Ward”, who was found to be a practicing physician and surgeon in the late 1800s, and cont...

  • Article
  • Open Access
8 Citations
3,603 Views
6 Pages

Association between Suicide and Toxoplasma gondii Seropositivity

  • Laura Alejandra Mendoza-Larios,
  • Fernando García-Dolores,
  • Luis Francisco Sánchez-Anguiano,
  • Jesús Hernández-Tinoco and
  • Cosme Alvarado-Esquivel

27 August 2021

This study aimed to determine the association between suicide and Toxoplasma gondii (T. gondii) seropositivity. Serum samples of 89 decedents who committed suicide (cases) and 58 decedents who did not commit suicide (controls) were tested for anti-T....

(This article belongs to the Special Issue Effects of Toxoplasma gondii Infection on Human Behaviour)
  • Article
  • Open Access
6 Citations
3,628 Views
11 Pages

Ethanol and Medical Psychotropics Co-Consumption in European Countries: Results from a Three-Year Retrospective Study of Forensic Samples in Spain

  • Maira Almeida-González,
  • Luis D. Boada,
  • Guillermo Burillo-Putze,
  • Luis A. Henríquez-Hernández,
  • Octavio P. Luzardo,
  • María P. Quintana-Montesdeoca and
  • Manuel Zumbado

31 December 2022

Ethanol and medical psychotropics (MPs) are legal psychoactive substances widely consumed in Western countries that are routinely detected in standard toxicological analyses at compulsory autopsies, and toxicokinetic interactions between these drugs...

(This article belongs to the Section Drugs Toxicity)
  • Article
  • Open Access
1,531 Views
11 Pages

Demographic Factors and Aortic Stenosis-Related Death Locations: A Cross-Sectional Analysis

  • Adam Bacon,
  • Hesham Abdalla,
  • Ramzi Ibrahim,
  • Mohamed Allam,
  • Maryam Emami Neyestanak,
  • Ghee Kheng Lim,
  • Xuan Ci Mee,
  • Hoang Nhat Pham,
  • Mahmoud Abdelnabi and
  • Kwan Lee
  • + 4 authors

14 March 2025

Background: Aortic stenosis (AS) imposes a significant mortality burden. Understanding demographic influences on the location of AS-related death is crucial for advancing equitable end-of-life care. Therefore, we investigated how demographic factors...

(This article belongs to the Section Cardiovascular Medicine)
  • Article
  • Open Access
12 Citations
1,003 Views
10 Pages

Temporal Association between Home Nursing and Hospital Costs at End of Life in Three Provinces

  • H. Seow,
  • R. Pataky,
  • B. Lawson,
  • E.M. O’Leary,
  • R. Sutradhar,
  • K. Fassbender,
  • K. McGrail,
  • L. Barbera,
  • F. Burge and
  • J.S. Hoch
  • + 1 author

1 February 2016

Background: Research has demonstrated that increases in palliative homecare nursing are associated with a reduction in the rate of subsequent hospitalizations. However, little evidence is available about the cost-savings potential of palliative nursi...

  • Article
  • Open Access
8 Citations
4,767 Views
23 Pages

Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease

  • Peter Simons,
  • Yan Guo,
  • Virginie Bondu,
  • Susan L. Tigert,
  • Michelle Harkins,
  • Samuel Goodfellow,
  • Cana Tompkins,
  • Devon Chabot-Richards,
  • Xuexian O. Yang and
  • Tione Buranda
  • + 3 authors

12 August 2021

Pathogenic New World orthohantaviruses cause hantavirus cardiopulmonary syndrome (HCPS), a severe immunopathogenic disease in humans manifested by pulmonary edema and respiratory distress, with case fatality rates approaching 40%. High levels of infl...

(This article belongs to the Section Human Virology and Viral Diseases)
  • Article
  • Open Access
47 Citations
18,738 Views
15 Pages

Substantial racial/ethnic and gender disparities in COVID-19 mortality have been previously documented. However, few studies have investigated the impact of individual socioeconomic position (SEP) on these disparities. Objectives: To determine the jo...

(This article belongs to the Section Infectious Disease Epidemiology)
  • Article
  • Open Access
30 Citations
6,695 Views
13 Pages

Polycyclic Aromatic Hydrocarbon Residues in Serum Samples of Autopsied Individuals from Tennessee

  • Aramandla Ramesh,
  • Anil Kumar,
  • Mounika P. Aramandla and
  • Alfred M. Nyanda

This study reports the concentrations of Polycyclic Aromatic Hydrocarbons (PAHs) in human blood sera samples (n = 650) obtained at autopsy from individuals who died of drug abuse, alcohol toxicity, homicide, suicide and other unknown causes. The anal...

  • Article
  • Open Access
4 Citations
11,641 Views
12 Pages

Feline Forensics: Revealing the Unique Decomposition of Cats

  • Kelly Bagsby,
  • Adam W. Stern and
  • Krystal R. Hans

24 March 2024

Limited data about the differences between the decomposition of animals with fur exist within the forensic veterinary medicine discipline. Due to the sheer number of animals used as animal models and the number of animals that exist, determining stag...

(This article belongs to the Section Veterinary Clinical Studies)
  • Article
  • Open Access
5 Citations
4,225 Views
11 Pages

Comparison of Palliative Care Models in Idiopathic Pulmonary Fibrosis

  • Sarah Younus,
  • Jeffrey A. Bakal,
  • Janice Richman-Eisenstat,
  • Ghadah Alrehaili,
  • Sharina Aldhaheri,
  • Michelle Morales,
  • Naomi Rippon,
  • Elisabeth Bendstrup,
  • Ingrid Harle and
  • Meena Kalluri
  • + 3 authors

28 September 2021

Introduction: Palliative care (PC) is recommended in idiopathic pulmonary fibrosis (IPF) patients but poorly implemented. Integration of PC into routine management by pulmonologists may improve overall and end-of-life (EOL) care, but the optimal mode...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Communication
  • Open Access
1 Citations
2,727 Views
9 Pages

Carbapenem Use in the Last Days of Life: A Nationwide Korean Study

  • Yu Mi Wi,
  • Ki Tae Kwon,
  • Cheon-Hoo Jeon,
  • Si-Ho Kim,
  • Soyoon Hwang,
  • Sohyun Bae,
  • Yoonjung Kim,
  • Hyun-Ha Chang,
  • Shin-Woo Kim and
  • Antimicrobial Stewardship Research Committee of Korean Society for Antimicrobial Therapy
  • + 11 authors

The appropriate use of carbapenem is a critical concern for patient safety and public health, and is a national priority. We investigated the nationwide status of carbapenem prescription in patients within their last 14 days of life to guide judiciou...

  • Article
  • Open Access
1,121 Views
15 Pages

Sexual Dimorphism of the Lateral Angle of the Petrous Bone in Children: Growth Patterns and the Influence of Cranial Width

  • Lukas Waltenberger,
  • Stefan Lettner,
  • Anton Dobsak,
  • Martin Dockner,
  • Lena Hirtler and
  • Stefan Tangl

29 May 2025

Background: The lateral angle of the internal acoustic meatus of the petrous bone is a sexually dimorphic feature used for sex determination, particularly in fragmented or cremated remains. However, studies show conflicting results regarding its accu...

  • Article
  • Open Access
1 Citations
1,551 Views
28 Pages

12 November 2024

The impact of uncertainty in information systems is difficult to assess, especially when drawing conclusions from human observation records. In this study, we investigate survival variation in a population experiencing infectious disease as a proxy t...

(This article belongs to the Section Complexity)
  • Communication
  • Open Access
4 Citations
3,362 Views
10 Pages

Decreased Administration of Life-Sustaining Treatment just before Death among Older Inpatients in Japan: A Time-Trend Analysis from 2012 through 2014 Based on a Nationally Representative Sample

  • Michi Sakai,
  • Shosuke Ohtera,
  • Tomohide Iwao,
  • Yukiko Neff,
  • Tomoe Uchida,
  • Yoshimitsu Takahashi,
  • Genta Kato,
  • Tomohiro Kuroda,
  • Shuzo Nishimura and
  • on behalf of BiDAME (Big Data Analysis of Medical Care for the Elderly in Kyoto)
  • + 1 author

The administration of intensive end-of-life care just before death in older patients has become a major policy concern, as it increases medical costs; however, care intensity does not necessarily indicate quality. This study aimed to describe the tem...

  • Article
  • Open Access
23 Citations
4,841 Views
11 Pages

Mortality and Associated Causes in Hemophagocytic Lymphohistiocytosis: A Multiple-Cause-of-Death Analysis in France

  • Solène La Marle,
  • Gaëlle Richard-Colmant,
  • Mathieu Fauvernier,
  • Hervé Ghesquières,
  • Arnaud Hot,
  • Pascal Sève and
  • Yvan Jamilloux

20 February 2023

Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome with an overall mortality rate of 40%. A multiple-cause-of-death analysis allows for the characterization of mortality and associated causes over an extended period. Deat...

(This article belongs to the Section Immunology & Rheumatology)
  • Article
  • Open Access
5 Citations
6,692 Views
18 Pages

27 December 2023

This study delves into the dynamics of relational energy (RE) within an organizational context, examining some of its antecedents and decedents. Specifically, it investigates the influence of psychological capital (PsyCap) and humor on RE, and, subse...

(This article belongs to the Special Issue Humor Use in Interpersonal Relationships)
  • Article
  • Open Access
13 Citations
4,840 Views
18 Pages

This study aims to translate and validate two perceived suicide stigma scales, including the Stigma of Suicide Attempt Scale (STOSA) and the Stigma of Suicide and Suicide Survivor Scale (STOSASS) into Chinese language, examining the factor structure,...

(This article belongs to the Special Issue Feature Papers in Public Health Statistics and Risk Assessment)
  • Technical Note
  • Open Access
18 Citations
7,546 Views
14 Pages

13 September 2021

Educational institutions in several countries state that the education sector should be modernized to ensure a contemporary, individualized, and more open learning process by introducing and developing advance digital solutions and learning tools. Vi...

(This article belongs to the Section Applied Systems on Educational Innovations and Emerging Technologies)
  • Article
  • Open Access
11 Citations
3,657 Views
13 Pages

Quality of End-of-Life Cancer Care in Canada: A 12-Year Retrospective Analysis of Three Provinces’ Administrative Health Care Data Evaluating Changes over Time

  • Amanda Farah Khan,
  • Hsien Seow,
  • Rinku Sutradhar,
  • Stuart Peacock,
  • Kelvin Kar-Wing Chan,
  • Fred Burge,
  • Kim McGrail,
  • Adam Raymakers,
  • Beverley Lawson and
  • Lisa Barbera

12 November 2021

This retrospective cohort study of cancer decedents during 2004–2015 examined end-of-life cancer care quality indicators (QIs) in the provinces of British Columbia (BC), Ontario, and Nova Scotia (NS). These included: emergency department use, in-pati...

(This article belongs to the Section Palliative and Supportive Care)
  • Article
  • Open Access
6 Citations
1,300 Views
7 Pages

Changes of heart geometry in patients with ischemic heart disease

  • Dalia Pangonytė,
  • Elena Stalioraitytė,
  • Danutė Kazlauskaitė,
  • Reda Žiuraitienė,
  • Zita Stanionienė and
  • Sonata Kerpauskienė

23 December 2007

Objective. The aim of the study was to determine ventricular and atrial cardiometric parameters at preinfarction and postinfarction stage of ischemic heart disease.

Object and methods. Cardiometric parameters (mass, endocardial surface area, the trac...

  • Article
  • Open Access
34 Citations
9,913 Views
17 Pages

Each year in the U.S. more than 7,000 adults aged 60 years and older die of suicide and as the population ages, these numbers are expected to increase. While sex is an important predictor of older adult suicide, differences between males and females...

(This article belongs to the Special Issue Suicide Prevention and Public Health)
  • Article
  • Open Access
1 Citations
2,377 Views
9 Pages

Quality of End-of-Life Care in Gastrointestinal Cancers: A 13-Year Population-Based Retrospective Analysis in Ontario, Canada

  • Caitlin SR Lees,
  • Hsien Seow,
  • Kelvin KW Chan,
  • Anastasia Gayowsky and
  • Aynharan Sinnarajah

24 November 2022

Population-based quality indicators of either aggressive or supportive care at end of life (EOL), especially when specific to a cancer type, help to inform quality improvement efforts. This is a population-based, retrospective cohort study of gastroi...

  • Article
  • Open Access
28 Citations
8,567 Views
28 Pages

Methods for estimating assigned, binary sex at birth from skeletonized remains have primarily been developed for specific population groups in the U.S. (e.g., African American, European American, Hispanic) and, thus, inherently rely on ancestry estim...

(This article belongs to the Collection The Rise of Forensic Anthropology and Documented Human Osteological Collections)
  • Article
  • Open Access
13 Citations
4,202 Views
9 Pages

Impact of the COVID-19 Pandemic on Pulmonary Hypertension Patients: Insights from the BNP-PL National Database

  • Aleksandra Mamzer,
  • Marcin Waligora,
  • Grzegorz Kopec,
  • Katarzyna Ptaszynska-Kopczynska,
  • Marcin Kurzyna,
  • Szymon Darocha,
  • Michal Florczyk,
  • Ewa Mroczek,
  • Tatiana Mularek-Kubzdela and
  • Jaroslaw D. Kasprzak
  • + 22 authors

We aimed to evaluate the clinical course and impact of the SARS-CoV-2 pandemic on the rate of diagnosis and therapy in the complete Polish population of patients (pts) with pulmonary arterial hypertension (PAH-1134) and CTEPH (570 pts) treated within...

(This article belongs to the Section Health Behavior, Chronic Disease and Health Promotion)
  • Article
  • Open Access
2,372 Views
31 Pages

Background/Objectives: Forensic anthropological analyses and reports include diverse information that may help in establishing identifications, cause or manner of death determinations, taphonomic alterations, or other circumstances involving decedent...

  • Article
  • Open Access
1,938 Views
16 Pages

1 March 2026

Cannabis is the most-used psychoactive drug in Aotearoa—New Zealand (NZ); recreational use remains illegal, while medicinal use was legalized in 2020. Cannabis use is associated with increased risk of injury; however, there is little known on t...

  • Communication
  • Open Access
2 Citations
818 Views
7 Pages

Detecting Mycobacterium tuberculosis Complex DNA, Based on Post-Mortem Examination of Hilar Lymph Nodes with Real-Time PCR: Initial Study

  • Wojciech Rzechorzek,
  • Michalina Szańkowska,
  • Benedykt Szczepankiewicz,
  • Agata Cyran-Chlebicka and
  • Aleksandra Safianowska

18 August 2014

Introduction: According to the WHO, almost a third of the world population are thought to be infected with Mycobacterium tuberculosis. Some studies of the prevalence of latent tuberculosis infection (LTBI) have already been performed in Poland, showi...

  • Article
  • Open Access
2 Citations
3,486 Views
7 Pages

Comprehensive Diagnostic Work-Up for Uncovering the Causes of Sudden Cardiac Death: The Role of Family Members

  • Emanuele Monda,
  • Gaetano Diana,
  • Daniele Bruno,
  • Marta Rubino,
  • Giuseppe Palmiero,
  • Federica Verrillo,
  • Chiara Cirillo,
  • Annapaola Cirillo,
  • Adelaide Fusco and
  • Giuseppe Limongelli
  • + 6 authors

Background: The aim of this study was to evaluate the performance of the diagnostic pathway proposed by the European Society of Cardiology (ESC) guidelines for identifying the underlying aetiology of sudden cardiac death (SCD) through the screening o...

(This article belongs to the Section Cardiovascular Genetics in Clinical Practice)
  • Article
  • Open Access
1,480 Views
34 Pages

Background/Objective: Most weight estimation formulae developed for children from skeletal measurements are based on 20 individuals from the Denver Growth Study. This limitation is mainly due to the availability of data. The formulae produced using t...

  • Review
  • Open Access
1 Citations
1,737 Views
30 Pages

Liver Xenotransplantation: From Early Primate Trials to the First-in-Human Porcine Bridging Therapies

  • Alexandru Grigorie Nastase,
  • Alin Mihai Vasilescu,
  • Ana Maria Trofin,
  • Nicolae Florin Iftimie,
  • Juan José Segura-Sampedro,
  • Ramona Cadar,
  • Iulian Buzincu,
  • Alexandra Davidescu,
  • Anda Lucia Nastase and
  • Cristian Dumitru Lupascu
  • + 2 authors

20 April 2026

Liver transplantation remains the definitive treatment for end-stage liver disease and acute liver failure, yet a critical and persistent shortage of donor organs results in thousands of preventable deaths annually worldwide. Xenotransplantation has...

(This article belongs to the Special Issue Clinical Advances in Abdominal Surgery)
  • Article
  • Open Access
8 Citations
5,326 Views
15 Pages

Death Is a Possibility for Those without Shelter”: A Thematic Analysis of News Coverage on Homelessness and the 2021 Heat Dome in Canada

  • Emily J. Tetzlaff,
  • Farah Mourad,
  • Nicholas Goulet,
  • Melissa Gorman,
  • Rachel Siblock,
  • Sean A. Kidd,
  • Mariya Bezgrebelna and
  • Glen P. Kenny

Among the most vulnerable to the health-harming effects of heat are people experiencing homelessness. However, during the 2021 Heat Dome, the deadliest extreme heat event (EHE) recorded in Canada to date, people experiencing homelessness represented...

(This article belongs to the Section Global Health)
  • Article
  • Open Access
2 Citations
2,509 Views
12 Pages

Residential Nitrogen Dioxide Exposure and Cause-Specific Cerebrovascular Mortality: An Individual-Level, Case-Crossover Study

  • Yifeng Qian,
  • Renzhi Cai,
  • Xiaozhen Su,
  • Qi Li,
  • Shan Jin,
  • Wentao Shi,
  • Renjie Chen,
  • Chunfang Wang and
  • Jia He

22 December 2023

Background: Existing studies have already shown a connection between nitrogen dioxide (NO2) exposure and cerebrovascular mortality. However, the differential effects of NO2 on cerebrovascular disease and its subtypes remain unclear and require furthe...

(This article belongs to the Section Air Pollution and Health)
  • Article
  • Open Access
47 Citations
1,863 Views
15 Pages

Quality of End-of-Life Cancer Care in Canada: A Retrospective Four-Province Study Using Administrative Health Care Data

  • L. Barbera,
  • H. Seow,
  • R. Sutradhar,
  • A. Chu,
  • F. Burge,
  • K. Fassbender,
  • K. McGrail,
  • B. Lawson,
  • Y. Liu and
  • A. Potapov
  • + 1 author

1 October 2015

Background: The quality of data comparing care at the end of life (eol) in cancer patients across Canada is poor. This project used identical cohorts and definitions to evaluate quality indicators for eol care in British Columbia, Alberta, Ontario, a...

  • Article
  • Open Access
19 Citations
1,229 Views
10 Pages

Population-Based Trends in Systemic Therapy Use and Cost for Cancer Patients in the Last Year of Life

  • R.E. Pataky,
  • W.Y. Cheung,
  • C. de Oliveira,
  • K.E. Bremner,
  • K.K.W. Chan,
  • J.S. Hoch,
  • M.D. Krahn and
  • S.J. Peacock

1 February 2016

Background: The use of systemic therapy near the end of life can expose cancer patients to severe toxicity for minimal survival gain and comes with a high cost. Early palliative care is recommended, but there is evidence that aggressive care remains...

of 2