- Hypothesis
Increased Dicarbonyl Stress as a Novel Mechanism of Multi-Organ Failure in Critical Illness
- Bas C. T. Van Bussel,
- Marcel C. G. Van de Poll,
- Casper G. Schalkwijk and
- Dennis C. J. J. Bergmans
Molecular pathological pathways leading to multi-organ failure in critical illness are progressively being unravelled. However, attempts to modulate these pathways have not yet improved the clinical outcome. Therefore, new targetable mechanisms shoul...