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10,607 Results Found

  • Hypothesis
  • Open Access
12 Citations
5,302 Views
9 Pages

Increased Dicarbonyl Stress as a Novel Mechanism of Multi-Organ Failure in Critical Illness

  • Bas C. T. Van Bussel,
  • Marcel C. G. Van de Poll,
  • Casper G. Schalkwijk and
  • Dennis C. J. J. Bergmans

Molecular pathological pathways leading to multi-organ failure in critical illness are progressively being unravelled. However, attempts to modulate these pathways have not yet improved the clinical outcome. Therefore, new targetable mechanisms shoul...

  • Article
  • Open Access
1,964 Views
15 Pages

Topic Modeling the Academic Discourse on Critical Incident Stress Debriefing and Management (CISD/M) for First Responders

  • Robert Lundblad,
  • Saul Jaeger,
  • Jennifer Moreno,
  • Charles Silber,
  • Matthew Rensi and
  • Cass Dykeman

Background/Objectives: This study examines the academic discourse surrounding Critical Incident Stress Debriefing (CISD) and Critical Incident Stress Management (CISM) for first responders using Latent Dirichlet Allocation (LDA) topic modeling. It ai...

  • Article
  • Open Access
2 Citations
2,755 Views
21 Pages

In recent years, cold-formed steel has been widely used in prefabricated steel structures, and the common cross-section forms are mainly complex lipped angle sections. However, there is a lack of design guidance for such a cross-section due to the co...

  • Feature Paper
  • Article
  • Open Access
21 Citations
9,923 Views
17 Pages

4 April 2021

In this study, the incipient motion of four groups of sand, ranging from medium to very coarse particles, was experimentally examined using an acoustic Doppler velocimeter (ADV) in different water depths under the hydraulically transitional flow cond...

  • Article
  • Open Access
14 Citations
4,050 Views
8 Pages

16 May 2018

The double differentiation method overestimates the critical stress associated with the initiation of dynamic transformation (DT) because significant amounts of the dynamic phase must be present in order for its effect on the work hardening rate to b...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,330 Views
13 Pages

Comparison of Critical Shear Stress of Rill Erosion Estimated from Two Methods

  • Ren Geng,
  • Qiu Jin,
  • Shaohua Lei,
  • Hongyuan Liu,
  • Bin Lu and
  • Meixiang Xie

17 June 2022

Various disputes exist regarding the critical shear stress (τc) of rill erosion determined by linear regression. Alternatively, some researchers have attempted to measure critical shear stress (τo) of rill erosion by observing the start of so...

  • Article
  • Open Access
346 Views
17 Pages

Critical Stress Conditions for Foam Glass Aggregate Insulation in a Flexible Pavement Layered System

  • Jean Pascal Bilodeau,
  • Erdrick Pérez-González,
  • Di Wang and
  • Pauline Segui

In cold regions, flexible pavements are vulnerable to frost-induced damage, necessitating effective insulation strategies. Foam glass aggregate (FGA) insulation layers, made from recycled glass, offer promising thermal insulation properties but are m...

  • Article
  • Open Access
624 Views
14 Pages

Mental health among university students is an issue of growing global concern, impacting both psychological well-being and academic outcomes. This study investigated the relationships between sleep quality, perceived stress, anxiety, and depression,...

  • Article
  • Open Access
15 Citations
4,026 Views
13 Pages

Perceived Stress and Coping Behavior of Nurses Caring for Critical Patients with COVID-19 Outbreak in Taiwan: A Mixed-Methods Study

  • Shu-Yen Lee,
  • Kai-Jo Chiang,
  • Yi-Jiun Tsai,
  • Chi-Kang Lin,
  • Yun-Ju Wang,
  • Chou-Ping Chiou and
  • Hsueh-Hsing Pan

Severe pneumonia with novel pathogens, also called COVID-19, caused a pandemic in Taiwan as well as in the rest of the world in May 2021. Nurses are under great stress when caring for critically ill patients with COVID-19. This study aimed to explore...

  • Article
  • Open Access
3 Citations
2,082 Views
18 Pages

26 August 2024

The mean stress effect remains a critical aspect in multiaxial fatigue analysis. This work presents a new criterion that, based on the classical Findley criterion, applies a material-dependent exponent to the mean normal stress term and includes the...

  • Article
  • Open Access
58 Citations
3,304 Views
20 Pages

Calcareous sand is a special marine soil rich in calcium carbonate minerals, characterized by brittle particles. It is, therefore, widely used as a filling material in the construction of islands and reefs. In this study, a series of cyclic tri-axial...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,255 Views
17 Pages

Study on the Relationship Between WC Coating Thickness and Residual Stress Using Critical Refracted Ultrasonic Longitudinal Waves

  • Darui Xu,
  • Xiangyu Zhang,
  • Vasiliy O. Pelenovich,
  • Oleksandr Pohrebniak,
  • Bing Yang,
  • Jun Zhang and
  • Yanming Chen

23 February 2025

Tungsten carbide (WC) coatings of varying thicknesses were prepared using electrical discharge deposition technology. Relevant characterizations were conducted to analyze the residual stress in the WC coatings from a microscopic perspective, and this...

  • Article
  • Open Access
1 Citations
2,412 Views
12 Pages

A Physically Based Model Predicting the Degradation of Hydrogen on Crack Growth Critical Stress Intensity Factor of Metals

  • Yuting Huang,
  • Jihan Chen,
  • Yanfei Wang,
  • Wei Liu,
  • Weijie Wu,
  • Xinfeng Li and
  • Xinyu Yang

29 August 2022

A simple, physically based model is developed to quantitatively predict the degradation of hydrogen on the crack growth critical stress intensity factor (CSIF) of metals. The model is formulated by combining a microscopically shielded Griffith criter...

  • Article
  • Open Access
1 Citations
1,258 Views
18 Pages

8 December 2024

In this paper, a comprehensive series of dynamic triaxial tests were conducted to delve into the influence of temperature and moisture content on the behavior of frozen silty clay. Upon scrutinizing the experimental outcomes under prolonged reciproca...

  • Article
  • Open Access
5 Citations
3,421 Views
19 Pages

19 December 2019

Measurement and control of stress in the metal forming layer is the basic problem of selective laser melting (SLM) forming parts. The critical refraction longitudinal (LCR) wave method to test stress in metallic materials has been extensively studied...

  • Feature Paper
  • Review
  • Open Access
22 Citations
15,954 Views
19 Pages

Overview: Post traumatic stress disorder (PTSD) has emerged as a severely debilitating psychiatric disorder associated with critical illness. Little progress has been made in the treatment of post-intensive care unit (ICU) PTSD. Aim: To synthesize ne...

  • Brief Report
  • Open Access
4 Citations
2,672 Views
7 Pages

27 January 2023

Emergency service workers encounter potentially traumatic incidents as part of their normal work duties. They are, therefore, at an increased risk of symptoms of poor mental health. In the past, post-critical incident seminars (PCIS) were offered to...

  • Article
  • Open Access
4 Citations
1,912 Views
14 Pages

11 February 2023

To investigate the dynamic stability of natural subgrade filler (NSF) and fiber-binder reinforced subgrade filler (RSF) under cyclic load after freeze–thaw (FT) cycles, a triaxial test was conducted to determine the correlation between cumulati...

  • Article
  • Open Access
35 Citations
11,021 Views
18 Pages

29 October 2018

This study deals with the numerical estimation of the fatigue life represented in the form of strength-life (S-N, or Wöhler) curves of metals with different crystallographic structures, namely body-centered cubic (BCC) and face-centered cubic (F...

  • Article
  • Open Access
8 Citations
2,284 Views
20 Pages

30 September 2021

Critical dynamic stress (σcri) and accumulative plastic strain (εp) are primary indicators regarding the dynamic stability of unbound granular materials (UGMs). This study aims to seek an effective method to evaluate the dynamic stability of UGMs use...

  • Article
  • Open Access
496 Views
13 Pages

De-Novo Stress Urinary Incontinence After Apical Prolapse Surgery: Potential Link with the Zone of Critical Elasticity

  • Yaman Degirmenci,
  • Ceren Efe Sayın,
  • Ina Shehaj,
  • Mona Wanda Schmidt and
  • Gilbert Georg Klamminger

17 November 2025

Background/Objectives: Pelvic organ prolapse (POP) surgery can lead to postoperative stress urinary incontinence (SUI) in previously continent women, termed de novo SUI. This study assessed the incidence and risk factors of de novo SUI after apical P...

  • Review
  • Open Access
1 Citations
7,966 Views
15 Pages

The Furosemide Stress Test: A Dynamic Tool for Predicting Acute Kidney Injury Progression in Critical Care Medicine

  • Luigi La Via,
  • Giuseppe Cuttone,
  • Nicola Sinatra,
  • Maurizio Giuseppe Abrignani,
  • Giulio Geraci,
  • Giovanni Ippati and
  • Francesca Maria Rubulotta

10 April 2025

Acute kidney injury (AKI) remains a significant challenge in critical care medicine, affecting up to 50% of intensive care unit patients with substantial mortality rates. While traditional approaches to AKI assessment rely on static measurements like...

  • Article
  • Open Access
18 Citations
6,453 Views
12 Pages

Assessing the Perceptions and Impact of Critical Incident Stress Management Peer Support among Firefighters and Paramedics in Canada

  • Jill A. B. Price,
  • Caeleigh A. Landry,
  • Jeff Sych,
  • Malcolm McNeill,
  • Andrea M. Stelnicki,
  • Aleiia J. N. Asmundson and
  • R. Nicholas Carleton

Relative to the general population, public safety personnel (PSP) appear at an increased risk of developing mental health challenges as a result of repeated exposure to potentially psychologically traumatic events (PPTEs). To help mitigate the impact...

  • Article
  • Open Access
2 Citations
3,007 Views
21 Pages

Perspectives and Experiences of Public Safety Personnel Engaged in a Peer-Led Workplace Reintegration Program Post Critical Incident or Operational Stress Injury: A Qualitative Thematic Analysis

  • Chelsea Jones,
  • Shaylee Spencer,
  • Elly O’Greysik,
  • Lorraine Smith-MacDonald,
  • Katherine S. Bright,
  • Amy J. Beck,
  • R. Nicholas Carleton,
  • Lisa Burback,
  • Andrew Greenshaw and
  • Yanbo Zhang
  • + 4 authors

Introduction: Public safety personnel (PSP) experience operational stress injuries (OSIs), which can put them at increased risk of experiencing mental health and functional challenges. Such challenges can result in PSP needing to take time away from...

  • Review
  • Open Access
10 Citations
4,000 Views
12 Pages

27 April 2022

Nutritional support is an important part of the treatment of critical ill children and the phase of disease has to be taken into account. The metabolic stress response during acute critical illness is characterized by severe catabolism. So far, there...

  • Article
  • Open Access
15 Citations
3,819 Views
12 Pages

31 January 2019

Critically refracted longitudinal (LCR) waves are commonly used to evaluate the residual stress of a material. The utilization of LCR waves is advantageous in that these waves are not sensitive to the texture of the material. Thus, LCR can be conside...

  • Article
  • Open Access
6 Citations
2,708 Views
15 Pages

19 September 2021

Acid rain deposition (AR) has long-lasting implications for the community stability and biodiversity conservation in southwest China. Acer catalpifolium is a critically endangered species in the rain zone of Western China where AR occurs frequently....

  • Commentary
  • Open Access
6 Citations
5,421 Views
11 Pages

28 November 2024

Autism spectrum disorder (ASD) is a neurodevelopmental disability that presents significant challenges in communication and behavior. ASD prevalence exceeds 2% among eight-year-old children and is at similar levels globally. We propose that critical...

  • Article
  • Open Access
5 Citations
1,550 Views
17 Pages

21 September 2024

Climatic changes have caused seasonal drought to occur frequently in tea fields of low-mountain and hill regions over the past decades. This leads to huge losses in the quality and yields of famous tea, which restricts the economic development of the...

  • Article
  • Open Access
3 Citations
2,540 Views
14 Pages

Comparison of n-3 PUFA-Enriched vs. Olive-Oil-Based Lipid Emulsion on Oxidative Stress and Inflammatory Response in Critically Ill Post-Surgery Adults: Secondary Analysis of a Randomized Controlled Trial

  • Nerea Cuartero-Corbalán,
  • Fátima Martínez-Lozano Aranaga,
  • Maria Jesús Gómez-Ramos,
  • María B. Gómez-Sánchez,
  • Francisco V. Avilés-Plaza,
  • María A. Núñez-Sánchez and
  • Juana M. Morillas-Ruiz

31 October 2024

Malnutrition in critically ill patients represents a major concern as it can lead to adverse outcomes including increased morbidity and mortality. These patients exhibit an impaired immune response accompanied by increased oxidative stress. Nutrition...

  • Article
  • Open Access
427 Views
28 Pages

26 November 2025

Notch and size effects significantly influence the fatigue performance of engineering components, which is crucial for ensuring structural integrity. A novel probabilistic fatigue life prediction Kt-V-L model considering both the size and the notch e...

  • Review
  • Open Access
802 Citations
27,264 Views
23 Pages

Oxidative Stress in Obesity: A Critical Component in Human Diseases

  • Lucia Marseglia,
  • Sara Manti,
  • Gabriella D’Angelo,
  • Antonio Nicotera,
  • Eleonora Parisi,
  • Gabriella Di Rosa,
  • Eloisa Gitto and
  • Teresa Arrigo

26 December 2014

Obesity, a social problem worldwide, is characterized by an increase in body weight that results in excessive fat accumulation. Obesity is a major cause of morbidity and mortality and leads to several diseases, including metabolic syndrome, diabetes...

  • Review
  • Open Access
2 Citations
1,674 Views
24 Pages

The Influence of Anesthetics on the Functions of the Endothelium and Oxidative Stress: A Critical Review

  • Marko Djuric,
  • Irina Nenadic,
  • Nina Radisavljevic,
  • Dusan Todorovic,
  • Maja Stojanovic,
  • Nemanja Dimic,
  • Marina Bobos,
  • Suzana Bojic,
  • Predrag Stevanovic and
  • Predrag Savic
  • + 3 authors

26 September 2025

Endothelial dysfunction (characterized by reduced vasodilation or vasoconstriction, oxidative stress, inflammation, and pro-thrombotic condition) is a critical factor in the pathophysiology of various cardiovascular conditions, and the application of...

  • Review
  • Open Access
1 Citations
3,749 Views
31 Pages

Post-traumatic stress disorder (PTSD), a mental disorder caused by exposure to traumatic stress, affects 5–10% of the world’s population. There is some evidence that PTSD is associated with accelerated cellular aging, leading to an increa...

  • Article
  • Open Access
3,598 Views
40 Pages

This paper captures a qualitative review of the regulatory prescribed stress tests for UK financial services designed by the Bank of England and the Prudential Regulation Authority (PRA)/Financial Conduct Authority (FCA) after the Global Financial Cr...

  • Article
  • Open Access
6 Citations
3,324 Views
15 Pages

The Critical Assessment of Oxidative Stress Parameters as Potential Biomarkers of Carbon Monoxide Poisoning

  • Piotr Hydzik,
  • Renata Francik,
  • Sławomir Francik,
  • Ewa Gomółka,
  • Ebru Derici Eker,
  • Mirosław Krośniak,
  • Maciej Noga and
  • Kamil Jurowski

In conventional clinical toxicology practice, the blood level of carboxyhemoglobin is a biomarker of carbon monoxide (CO) poisoning but does not correspond to the complete clinical picture and the severity of the poisoning. Taking into account articl...

  • Article
  • Open Access
3 Citations
3,568 Views
11 Pages

Experimental Study on Critical Parameters Degradation of Nano PDSOI MOSFET under TDDB Stress

  • Tianzhi Gao,
  • Jianye Yang,
  • Hongxia Liu,
  • Yong Lu and
  • Changjun Liu

27 July 2023

In today’s digital circuits, Si-based MOS devices have become the most widely used technology in medical, military, aerospace, and aviation due to their advantages of mature technology, high performance, and low cost. With the continuous integr...

  • Communication
  • Open Access
910 Views
11 Pages

StarD5 Plays a Critical Role in the Hepatocyte ER Stress Survival Response

  • William M. Pandak,
  • Genta Kakiyama and
  • Daniel Rodriguez-Agudo

The unfolded protein response (UPR) is a highly orchestrated survival response initiated in cells under endoplasmic reticulum (ER) stress. Steroidogenic acute regulatory-related lipid transfer domain 5 (StarD5) is an ER stress-responsive, cholesterol...

  • Article
  • Open Access
27 Citations
4,756 Views
25 Pages

6 September 2023

Fatigue damage accumulation will not only cause the degradation of material performance but also lead to the growth of effective stress and critical stiffness. However, the existing fatigue reliability models usually ignore the effective stress growt...

  • Article
  • Open Access
3 Citations
4,801 Views
19 Pages

1 June 2022

The research presented is directed to identify the ways to reduce stress state in critical areas of the C-frame of mechanical presses. Ribbing is a way to increase rigidity and a means to reduce energy consumption in operation. Hence, the objective i...

  • Article
  • Open Access
1,590 Views
17 Pages

27 April 2023

Buckled graphene has potential applications in energy harvest, storage, conversion, and hydrogen storage. The investigation and quantification analysis of the random porosity in buckled graphene not only contributes to the performance reliability eva...

  • Article
  • Open Access
7 Citations
2,309 Views
14 Pages

27 February 2021

In this paper, the fracture of notched polymeric specimens under compressive stresses was investigated both experimentally and theoretically. In the experimental section, to determine the load-carrying capacity (LCC) of U-notched specimens made of ge...

  • Article
  • Open Access
52 Citations
4,974 Views
14 Pages

28 June 2021

Crop photosynthesis is closely related to leaf water content (LWC), and clarifying the LWC conditions at critical points in crop photosynthesis has great theoretical and practical value for accurately monitoring drought and providing early drought wa...

  • Article
  • Open Access
1 Citations
1,829 Views
16 Pages

In steel structures, skew thin steel plates serve as panel zones in structures spanning large spaces (e.g., warehouses and gymnasiums). Considerable research has been conducted on the shear buckling of panels due to seismic loads acting on a structur...

  • Review
  • Open Access
3 Citations
3,350 Views
13 Pages

The Universally Conserved Unconventional G Protein YchF Is Critical for Growth and Stress Response

  • Zhaoheng Lin,
  • Rongfang Li,
  • Zhiwei Han,
  • Yi Liu,
  • Liyang Gao,
  • Suchang Huang,
  • Ying Miao and
  • Rui Miao

20 April 2023

The ancient guanine nucleotide-binding (G) proteins are a group of critical regulatory and signal transduction proteins, widely involved in diverse cellular processes of all kingdoms of life. YchF is a kind of universally conserved novel unconvention...

  • Article
  • Open Access
9 Citations
4,470 Views
40 Pages

22 October 2019

This study presents a new interface for wellbore stability analysis, which visualizes and quantifies the stress condition around a wellbore at shear and tensile failure. In the first part of this study, the Mohr–Coulomb, Mogi–Coulomb, mod...

  • Article
  • Open Access
10 Citations
4,078 Views
11 Pages

17 June 2020

The paper introduces a valuable new description of fatigue strength in relation to material properties and thus a new perspective on the overall understanding of the fatigue process. Namely, a relation between the endurance limits and the accompanyin...

  • Article
  • Open Access
609 Views
17 Pages

Transcriptome Analysis Reveals Critical Genes Involved in the Response of Stropharia rugosoannulata to High Temperature and Drought Stress

  • Shengze Yan,
  • Shengyou Wang,
  • Meirong Zhan,
  • Xianxin Huang,
  • Ting Xie,
  • Ruijuan Wang,
  • Huan Lu,
  • Qingqing Luo and
  • Wei Ye

In this study, the differences in gene expression of Stropharia rugosoannulata at different treatment times under high temperature and drought stress were analyzed by transcriptomics. Here, a total of 74,571 transcripts and 16,233 unigenes were ident...

  • Article
  • Open Access
5 Citations
3,246 Views
21 Pages

2 September 2020

This publication is intended to present a new way of estimating the fatigue life of various construction materials. Carpinteri’s proposal was modified by replacing the fatigue limits ratio with the value of the normal to shear stress ratio for...

  • Article
  • Open Access
5 Citations
2,058 Views
20 Pages

12 August 2024

Drought stress has serious effects on the growth and yield of wheat in both productivity and quality and is an abiotic factor. Traditional methods of crop drought stress monitoring have some deficits. This work has been conducted in order to enhance...

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