Hydrogels have many different applications in the field of regenerative medicine. Biodegradable, injectable hydrogels could be utilized as delivery systems, cell carriers, and scaffolds for tissue engineering. Injectable hydrogels are an appealing sc...
Hydrogels are macromolecular networks able to absorb and release water solutions in a reversible manner, in response to specific environmental stimuli. Such stimuli-sensitive behaviour makes hydrogels appealing for the design of ‘smart’ devices, appl...
This article provides insights into hydrogels of the most promising biodegradable natural polymers and their mechanisms of degradation, highlighting the different possibilities of controlling hydrogel degradation rates. Since biodegradable hydrogels...
This research work deployed free radical polymerization for the development of pH-responsive hybrid nanocomposite hydrogels (NCHs) with the formation of improved interpenetrating networks (IPN). The crosslinked biopolymeric system was composed of (ch...
Hydrogels evolved as an outstanding carrier material for local and controlled drug delivery that tend to overcome the shortcomings of old conventional dosage forms for small drugs (NSAIDS) and large peptides and proteins. The aqueous swellable and cr...
Hydrogels have emerged as promising biomaterials due to their excellent performance; however, their biocompatibility, biodegradability, and absorbability still require improvement to support a broader range of medical applications. This paper present...
Multi-layer cell constructs produced in vitro are an innovative treatment option to support the growing demand for therapy in regenerative medicine. Our research introduces a novel construct integrating organ-derived decellularised extracellular matr...
We proposed a novel strategy in the fabrication of biodegradable poly(acrylic acid-co-acrylamide)/poly(vinyl alcohol) (P(AAc-co-Am)/PVA) double network (DN) hydrogels with good mechanical and self-healing properties. In the DN hydrogel system, P(AAc-...
A series of PDLLA-PEG1k-PDLLA tri-block co-polymers with various compositions, i.e., containing 2–10 lactoyl units, were prepared via ring opening polymerisation of d,l-lactide in the presence of poly (ethylene glycol) (PEG) (Mn = 1000 g·mol−1) as th...
The stimuli-sensitive and biodegradable hydrogels are promising biomaterials as controlled drug delivery systems for diverse biomedical applications. In this study, we construct hybrid hydrogels combined with peptide-based bis-acrylate and acrylic ac...
The possibility of increasing the complexity of the operational properties of environmentally safe biodegradable polymer hydrogel materials based on hydroxypropyl methylcellulose due to modification by humic acids from lignite is considered. As a res...
There is a great demand for biodegradable hydrogel, and cellulose enriched wastes materials are widely used to serve this purpose for various advance applications (e.g., biomedical and environmental). Sugarcane bagasse is cellulose-enriched agro-wast...
As micron-sized objects, mobile microrobots have shown significant potential for future biomedical applications, such as targeted drug delivery and minimally invasive surgery. However, to make these microrobots viable for clinical applications, sever...
Extracellular matrix (ECM) hydrogel promotes tissue regeneration in lesion cavities after stroke. However, a bioscaffold’s regenerative potential needs to be considered in the context of the evolving pathological environment caused by a stroke. To ev...
Preparation of stable hydrogels using physically (electrostatically) interacting charge-complementary polyelectrolyte chains seems to be more attractive from a practical point of view than the use of organic crosslinking agents. In this work natural...
In this study, a cellulose-based hydrogel was derived from olive pomace through a three-stage valorization process. In the first stage, cellulose was extracted from de-oiled olive pomace, yielding 9.16%. In the second stage, the extracted cellulose w...
Conventional seedling substrates such as rockwool and peat raise environmental concerns associated with disposal and resource extraction. Here, we investigate nanoclay–agarose hydrogels as candidate sustainable and biodegradable alternatives fo...
Polyvinyl alcohol (PVA) hydrogels are promising implants due to the similarity of their low-friction behavior to that of cartilage tissue, and also due to their non-cytotoxicity. However, their poor mechanical resistance and insufficient durability r...
Climate change and the impacts related to nonbiodegradable synthetic materials highlight the need for sustainable alternatives. Biopolymers from renewable sources show great potential for producing hydrogels, which are three-dimensionally crosslinked...
To improve the efficient use of nitrogen and decrease the environmental pollution of N losses, a novel and biodegradable composite hydrogel was prepared by chemical cross-linking synthesis using gelatin (Gel), chitosan (CS) and polylactic acid (PLA)...
This study evaluated the in vitro characterizations of biodegradable hydrogel beads with calcium phosphate bone cement (CPC). Commercial fast-setting CPC and hydrogel beads were compared with 25%-volume hydrogel in CPC (C/0.25) in vivo. The histologi...
Biodegradable hydrogel-based conductive inks, with application in additive circuit manufacturing, are synthesized from agarose, sodium alginate and functional carbon-based particles (carbon nanotubes and graphite). Rheological measurements are conduc...
Downgrading in the yield of crop is due to the inadequate availability of water. The way out for this trouble is to construct synthetic resources dependent on natural polymers with great water absorption and preservation limits. The present study inv...
The development of functional materials that promote the infiltration and retention of water and the controlled release of fertilizers and nutrients in soil is of interest in agriculture. In this context, hydrogels, three-dimensional polymeric struct...
This study attempts to address the challenge of accurately measuring the degradation of biodegradable hydrogels, which are frequently employed in drug delivery for controlled and sustained release. The traditional method utilizes a mass-loss approach...
Efficient drug delivery systems are essential for improving patient outcomes. Acetaminophen (AP), which is a kind of oral administration, is a commonly used pain reliever and fever reducer. However, oral administration carries various health risks, e...
New composite 3D scaffolds were developed as a combination of synthetic polymer, poly(2-hydroxyethyl methacrylate) (PHEMA), and a natural polymer, gelatin, with a ceramic component, nanohydroxyapatite (ID nHAp) dopped with metal ions. The combination...
Through the control of the molecular weight, water content and monomer concentration, polyethylene glycol dimethacrylate (PEGDMA) based hydrogels have been adapted for numerous applications, including as structural scaffolds, drug delivery vehicles a...
Lead (Pb2+) pollution poses a severe threat to the ecological environment and human health due to its high toxicity, bioaccumulation, and refractory nature. Traditional treatment technologies for lead-contaminated wastewater, such as chemical precipi...
In this paper, injectable, thermosensitive smart hydrogel local drug delivery systems (LDDSs) releasing the model antitumour drug 5-fluorouracil (5-FU) were developed. The systems were based on biodegradable triblock copolymers synthesized via ring o...
Poly(N-isopropylacrylamide) (P(NIPAAm)) hydrogels were prepared by free-radical polymerization with biodegradable poly (β-amino ester) (PBAE) crosslinkers at 1 wt% and 3 wt% ratio, and compared with conventional N,N′-methylene bisacrylamid...
Recently, the development of new materials with the desired characteristics for functional tissue engineering, ensuring tissue architecture and supporting cellular growth, has gained significant attention. Hydrogels, which possess similar properties...
We investigated the release behavior of glucagon-like peptide-1 (GLP-1) from a biodegradable injectable polymer (IP) hydrogel. This hydrogel shows temperature-responsive irreversible gelation due to the covalent bond formation through a thiol-ene rea...
Developing an exceptional reaction medium with high promotion efficiency, desirable biodegradability and good recyclability is necessary for hydrate-based methane storage. In this work, a kind of eco-friendly hydrogel, polyvinyl alcohol-co-acrylic ac...
Drought and water shortage are serious problems in many arid and semi-arid regions. This problem is getting worse and even continues in temperate climatic regions due to climate change. To address this problem, the use of biodegradable hydrogels is i...
Recently, we reported the synthesis and characterization of a new dextran derivative obtained by grafting polyethylene glycol methacrylate to a polysaccharide backbone through a carbonate bond. This moiety was introduced because it allows for the fab...
The complex nature of the ocular drug delivery barrier presents a significant challenge to the effective administration of drugs, resulting in poor therapeutic outcomes. To address this issue, it is essential to investigate new drugs and alternative...
Researchers have been investigating the physical and morphological properties of biodegradable polymer and copolymer films, blending them with other chemicals to solve challenges in medical, industrial, and eco-environmental fields. The present study...
Due to the growing demand for sustainable hygiene products (that will exhibit biodegradability and compostability properties), the challenge of developing a superabsorbent polymer that absorbs significant amounts of liquid has been raised so that it...
Supramolecular hydrogels based on chitosan and monoaldehydes are biomaterials with high potential for a multitude of bioapplications. This is due to the proper choice of the monoaldehyde that can tune the hydrogel properties for specific practices. I...
Cryogels obtained by the cryotropic gelation process are macroporous hydrogels with a well-developed system of interconnected pores and shape memory. There have been significant recent advancements in our understanding of the cryotropic gelation proc...
In the past couple of years, cellulose has attracted a significant amount of attention and research interest due to the fact that it is the most abundant and renewable source of hydrogels. With increasing environmental issues and an emerging demand,...
Current trends in intelligent hydrogels design for tissue engineering demand multifunctional biomaterials that respond to external stimuli, while maintaining adhesion, controlled degradation, and cytocompatibility. The present work describes the synt...
The development of superabsorbent hydrogels is experiencing a transformative era across industries. While traditional synthetic hydrogels have found broad utility, their non-biodegradable nature has raised environmental concerns, driving the search f...
The growing global demands for food security, efficient water use, and environmentally resilient agricultural strategies call for a sustainable agricultural revolution. Water scarcity, the excessive use of pesticides, and soil degradation are viewed...
In this work, crosslinkers were prepared by conjugating high- and low-molecular-weight gelatin with different mole ratios of itaconic acid (IA) with double bonds. Then, the gelatin-itaconic acid (gelatin-IA) crosslinkers were compared with the gelati...
This study investigates pH-sensitive hydrogels based on biocompatible, biodegradable polysaccharides and natural polymers such as chondroitin sulfate and alginate in combination with synthetic monomer such as acrylic acid, as controlled drug carriers...
Hydrogels are widely known for their ability to increase soil water retention and for their potential slow nutrient release mechanism. They have been constantly improved to meet the growing demand for sustainability in agriculture. Research focused o...
Hydrogel-gated synaptic transistors offer unique advantages, including biocompatibility, tunable electrical properties, being biodegradable, and having an ability to mimic biological synaptic plasticity. For processing massive data with ultralow powe...
Thermo-responsive diblock copolymers composed of hydrophilic methoxy poly(ethylene glycol) (MPEG) and hydrophobic biodegradable polyesters were prepared for application as injectable drug delivery systems, because they show a thermo-responsive sol-to...
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