The aim of this study is to evaluate the adhesion ability of okra gum, which is gaining popularity as a tablet binder. For this purpose, gum was extracted from okra pods, and the binding strength of different concentrations (1%, 3%, and 5%) was deter...
While Portland cement produces large amounts of carbon dioxide, low-calcium high-strength cements effectively reduce carbon emissions by decreasing the proportion of high-calcium minerals. In order to enhance the practical application value of low-ca...
The selective paste intrusion (SPI) describes a selective binding, additive manufacturing method. SPI bonds thin layers of aggregate by cement paste locally. Currently, SPI can achieve higher compressive strength, durability, and easier unpacking beh...
We investigated the influence of a solvent’s composition on the stability of desorbed and multiply charged RNAse S ions by analyzing the non-covalent complex’s gas-phase dissociation processes. RNAse S was dissolved in electrospray ionization-compati...
Origins-of-life research requires searching for a plausible transition from simple chemicals to larger macromolecules that can both hold information and catalyze their own production. We have previously shown that some group I intron ribozymes posses...
We have used a simple model system to test the prediction that surface attachment strength of filaments presenting a torsion would affect their shape and properties. FtsZ from E. coli containing one cysteine in position 2 was covalently attached to a...
A novel ambidentate dipeptide conjugate (H(L1)) containing N-donor atoms of the peptide part and an (O,O) chelate at the hydroxypyridinone (HP) ring is synthesized and characterized. It is hoped that this chelating ligand can be useful to obtain mult...
The RNA viruses SARS-CoV, SARS-CoV-2 and MERS-CoV encode the non-structural Nsp16 (2′-O-methyltransferase) that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to the first ribonucleotide in mRNA. Recently, it has been...
Proton binding (i.e., charging) isotherms of halloysite nanotubes (HNT) were determined from cycled acid-base potentiometric titrations in KCl solution at constant ionic strengths (0.01, 0.10, 1.00 mol dm−3). The isotherms measured in the pH cy...
κ-Conotoxin-PVIIA (κ-PVIIA) is a potassium-channel blocking peptide from the venom of the fish-hunting snail, Conus purpurascens, which is essential for quick prey’s excitotoxic immobilization. Binding of one κ-PVIIA to Shaker...
Titanium-extracted tailing slag (TETS) has high activity, but the content of chloride ions is high. To effectively bind the chloride ions, CaO was used to activate the TETS, and the solidified cementitious material of CaO-activated TETS was prepared....
Electrospray mass spectrometry is applied to determine apparent binding energies and quasi equilibrium dissociation constants of immune complex dissociation reactions in the gas phase. Myoglobin, a natural protein-ligand complex, has been used to dev...
Hydrogen bonds (HB)s are the most abundant motifs in biological systems. They play a key role in determining protein–ligand binding affinity and selectivity. We designed two pharmaceutically beneficial HB databases, database A including ca. 12,...
The interactions between model polyanions and polycations have been studied using frontal continuous capillary electrophoresis (FACCE) which allows the determination of binding stoichiometry and binding constant of the formed polyelectrolyte complex...
Protein binding prevents uremic toxins from removal by conventional extracorporeal therapies leading to accumulation in maintenance dialysis patients. Weakening of the protein binding may enhance the dialytic elimination of these toxins. In ultrafilt...
Chloride erodes steel bars through concrete pores, seriously affecting the durability of reinforced concrete structures. Improving the binding ability to chloride is an important measure. We explored the effects of W/C, curing age, and premixed Cl&mi...
In this present work, three generations of dendrigraft poly(l-Lysine) (DGL) were studied regarding their ability to interact with linear poly (acrylamide-co-2-acrylamido-2-methyl-1-propanesulfonate) (PAMAMPS) of different chemical charge densities (3...
Vegetable-oils-based pressure-sensitive adhesives (PSAs) are being developed as a substitute for petrochemical-based PSAs for application in daily life. However, vegetable-oils-based PSAs face the problems of unsatisfactory binding strengths and easy...
Coke breeze, a solid waste generated during coke production, transportation and utilization, possesses physicochemical properties akin to metallurgical coke except for its finer particle size. Recycling this material offers an effective route to cons...
The evolution of SARS-CoV-2, particularly the emergence of Omicron variants, has raised questions regarding changes in its binding affinity to the human angiotensin-converting enzyme 2 receptor (hACE2). Understanding the impact of mutations on the in...
The disposal of industrial wastewater (IWW) discharged from factories is a significant topic in the environment field, and the use of cement-based materials is a useful way to treat materials with unexpected ions. In this work, IWW with abundant SO42...
Inhibition of the major human drug-metabolizing cytochrome P450 3A4 (CYP3A4) by pharmaceuticals and other xenobiotics could lead to toxicity, drug–drug interactions and other adverse effects, as well as pharmacoenhancement. Despite serious clin...
The influence of structural features of three serpentine-group minerals (antigorite, chrysotile, and lizardite) on the hydration of heat-treated materials and the formation of magnesium silicate binder has been studied. Initial serpentine samples hav...
Polymer-coated steel (PCS) is a new type of metal packaging material under development, which has better performance in saving resources, energy, and environmental protection. The lamination process has an important influence on the bonding quality o...
Carbon/carbon composites, when used as bone implant materials, do not adhere well to the bone tissues because of their non-bioactive characteristics. Therefore, we electro-deposited SiC-hydroxyapatite coatings (with an ultrasound-assisted step) on ca...
The cement industry is a major contributor to global CO2 emissions, necessitating the development of low-carbon alternatives, such as alkali-activated slag cement (AAS). This study investigates the feasibility of using NaCl and NaOH as co-activators...
Commercialization of anion exchange membrane fuel cells (AEMFCs) has been limited due to the chemical degradation of various quaternary ammonium (QA) head groups, which affects the transportation of hydroxide (
The ability of a natural ice-binding protein from Shewanella frigidimarina (SfIBP) to inhibit ice crystal growth in highly alkaline solutions with increasing pH and ionic strength was investigated in this work. The purity of isolated SfIBP was first...
This article examines the interaction of clay minerals with iron ore concentrate in the context of the efficient use of composite mineral resources. The role of the adsorption properties of mineral additives in the formation of interparticle bonds in...
This work studies the phase composition, structure and mechanical properties of composite materials obtained by high-temperature vacuum sintering of SHS-fabricated CrNi–TiN powders synthesized in semi-industrial-scale production conditions. It was fo...
The global battle against the COVID-19 pandemic relies strongly on the human defense of antibody, which is assumed to bind the antigen’s receptor binding domain (RBD) with its hypervariable region (HVR). Due to the similarity to other viruses such as...
Ribavirin, 1-(β-D-Ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, which is included in the list of drugs recommended in the guidelines for the diagnosis and treatment of SARS-CoV-2 infection, has been the subject of experimental and theoretical...
Investigations on binding strength differences of non-covalent protein complex components were performed by mass spectrometry. T4 fibritin foldon (T4Ff) is a well-studied miniprotein, which together with its biotinylated version served as model syste...
The performance of aptamer-based biosensors is crucially impacted by their interactions with physiological metal ions, which can alter their structures and chemical properties. Therefore, elucidating the nature of these interactions carries the utmos...
Concrete in which EPS (expanded polystyrene) particles partially or completely replace concrete aggregates is called EPS concrete. Compared to traditional concrete, EPS concrete has a controllable low density and good thermal-insulation performance,...
Intact Transition Epitope Mapping—One-step Non-covalent force Exploitation (ITEM-ONE) analysis reveals an assembled epitope on the surface of Pertuzumab, which is recognized by the anti-Pertuzumab affimer 00557_709097. It encompasses amino acid...
The cohesive performance and durability of the bonding layer with semiconductor substrates are of paramount importance for realizing the high thermal conductivity capabilities of diamond. Utilizing electron beam evaporation and the room-temperature,...
Monotonic axial compression tests were carried out on 16 steel fiber-reinforced concrete (SFRC) columns confined by rectangular spiral stirrups. The impacts of stirrup spacing, stirrup strength, concrete strength, and cross-sectional aspect ratio on...
Biomass is one of the most important sources of renewable energy, generating large amounts of ash. This increases the amount of waste, landfill, and air pollution. This work focuses on the sustainable disposal of this ash by producing an innovative b...
Geometries, equilibrium dissociation energies (De), intermolecular stretching, and quadratic force constants (kσ) determined by ab initio calculations conducted at the CCSD(T)/aug-cc-pVTZ level of theory, with De obtained by using the complete...
E. coli O157:H7 is a pathogenic bacterium producing verotoxins that could lead to serious complications such as hemolytic uremia syndrome. Fast detection of such pathogens is important. For rapid detection, aptamers are quickly gaining traction as al...
The formation and evolution of SmCo5/Sm2Co17 (1:5H/2:17R/H) cellular structures play an essential role in understanding the coercivity of Sm-Co magnets. Herein, the pristine and different elemental-doped 1:5/2:17R and 1:5/2:17H interfaces are investi...
Understanding the thermal aging behavior of SiO2f/PI composites is crucial for ensuring their reliability and longevity in high-temperature aerospace applications. In this study, the thermal aging behavior of three-dimensional quartz-fiber-reinforced...
In this paper, the quartz crystal microbalance with dissipation monitoring (QCM-D) was used to investigate hydrophobicity and binding strength (KD) for 10 different drugs interacting with human serum albumin (HSA). Quantitative structure activity rel...
Background/Objectives: The unprecedented structural and binding data for antibodies to the SARS-CoV-2 virus taken together with the mutations for the spike protein allows for a broad simulation study of antibody–spike protein binding. This prov...
An intramolecular interaction between the p53 transactivation and DNA binding domains inhibits DNA binding. To study this autoinhibition, we used a fragment of p53, referred to as ND WT, containing the N-terminal transactivation domains (TAD1 and TAD...
Transcription factors must scan genomic DNA, recognize the cognate sequence of their control element(s), and bind tightly to them. The DNA recognition process is primarily carried out by their DNA binding domains (DBD), which interact with the cognat...
The Ebola virus is a deadly pathogen that has been threatening public health for decades. Recent studies have revealed alternative viral invasion routes where Ebola virus approaches cells via interactions among phosphatidylserine (PS), PS binding lig...
A bacon-type meat analogue consists of different structural layers, such as textured protein and a fat mimetic. To obtain a coherent and appealing product, a suitable binder must glue those elements together. A mixture based on pea protein and sugar...
Chelating agents are commonly employed in microelectronic processes to prevent metal ion contamination. The ligand fragments of a chelating agent largely determine its binding strength to metal ions. Identification of ligands with suitable characteri...
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