This paper contains a comprehensive study regarding the synthesis and physicochemical properties of new hexasubstitued benzene derivatives. In this work, three compounds of this type (including two electropolymerisable monomers) were synthesized in a...
In this study, Benzene-1,3,5-tricarboxylic acid (BTA)-functionalized gum (Cherry gum) (gum-Pr-BTA) was prepared as a novel nanocatalyst. This novel nanocatalyst was used for the expeditious and efficient synthesis of 1,4-polyhydroquinoline derivative...
Gallnut water extract (GWE) enriches 80~90% of gallnut tannic acid (TA). In order to study the biodegradation of GWE into gallic acid (GA), the LHS-1 strain, a variant of Aspergillus niger, was chosen to determine the optimal degradation parameters f...
Eight thia- or azasubstituted butyric acid derivatives were prepared and the influence of these substituents on the chemical shifts of the benzene ring carbon atoms was studied.
Background: Based on our previously reported series of novel 1,3,5-tris[(4-(substituted-aminomethyl)phenyl)methyl]benzene and 1,3,5-tris[(4-(substituted-aminomethyl)phenoxy)methyl]benzene derivatives, we have now designed, synthesized, and tested a n...
The identification of novel molecular systems with high fluorescence and significant non-linear optical (NLO) properties is a hot topic in the continuous search for new emissive probes. Here, the photobehavior of three two-arm bis[(dimethylamino)styr...
Glyoxalase-I (Glo-I) enzyme was established to be a valid target for anticancer drug design. It performs the essential detoxification step of harmful byproducts, especially methylglyoxal. A robust computer-aided drug design approach was used to desig...
Indoor air contamination in office rooms is regarded as one of the most important issues in the protection of workers’ health, because contaminants, even those occurring at low concentrations, can cause health problems for the office staff in v...
Intramolecular interactions are shown to be key for favoring a given structure in systems with a variety of conformers. In ortho-substituted benzene derivatives including a beryllium moiety, beryllium bonds provide very large stabilizations with resp...
Urea benzene derivatives (UBD) with amphiphilic side chains showed self-assembly behavior in aqueous solution to form nanoparticles ~100 nm in size. Subsequent thermal treatment led to additional self-assembly of the nanoparticles due to dehydration...
Two of the most hazardous benzene derivatives (HBD) that have polluted the aquatic environment are bromobenzene and chlorobenzene. Ferrate can degrade various pollutants quickly and efficiently without producing harmful byproducts. This study aims to...
A series of new 1,3,5-tris[(4-(substituted-aminomethyl)phenyl)methyl]benzene compounds were designed, synthesized, and evaluated in vitro against two parasites (Plasmodium falciparum and Leishmania donovani). The biological results showed antimalaria...
The potential migration of chemical compounds from plastic food packaging poses significant health risks, necessitating continuous monitoring and enhanced safety protocols. This study aimed to investigate the migration of nine chemical groups, includ...
A number of 1,4-bis(phenylethynyl)benzene derivatives (BPEBs) and their analogues with different numbers of side-substitute fluorine atoms on benzene rings, and alkyl chains, ethoxyl groups, fluorine atoms and trifluoromethyl groups as the end groups...
Gold catalysts possess the advantages of water and oxygen resistance, with the possibility of catalyzing many novel chemical transformations, especially in the syntheses of small-molecule skeletons, in addition to achieving the rapid construction of...
Ninhydrin-based fluorometric quantification of phenylalanine is one of the most widely used methods for hyperphenylalaninemia (HPA) screening in neonates due to its high sensitivity, high accuracy, and low cost. Here we report an increase of false po...
Gases, such as nitrogen dioxide, formaldehyde and benzene, are toxic even at very low concentrations. However, so far there are no low-cost sensors available with sufficiently low detection limits and desired response times, which are able to detect...
Sustainable hydrogen production is one of the main challenges today in the transition to a green and sustainable economy. Photocatalytic hydrogen production is one of the most promising technologies, amongst which BiVO4-based processes are highly att...
It has been found that two-dimensional materials, such as graphene, can be used as remarkable gas detection platforms as even minimal chemical interactions can lead to distinct changes in electrical conductivity. In this work, epitaxially grown graph...
HIV-1 capsid (CA) performs multiple roles in the viral life cycle and is a promising target for antiviral development. In this work, we describe the design, synthesis, assessment of antiviral activity, and mechanistic investigation of 20 piperazinone...
The impact of the chalcogen atomic electronegativity (O, S, and Se atoms) of new organic molecules on excited-state dynamical reactions is self-evident. Inspired by this kind of distinguished photochemical characteristic, in this work, we performed a...
A 1,4-bis((9H-carbazol-9-yl)methyl)benzene (DCB)-containing homopolymer (P(DCB)) and four DCB- and ED-derivative (3,4-ethylenedioxythiophene (EDOT) and 3,4-ethylenedioxythiophene-methanol (EDm))-containing copolymers (P(DCB-co-ED), P(2DCB-co-ED), P(D...
UV/chlorine advanced oxidation process (AOP), as a potential alternative to UV/H2O2 in water treatment, may pose a potential risk of increased disinfection by-product (DBP) formation and is of great concern. In this paper, seven benzene derivatives,...
Qualitative chemical fingerprinting of the honey volatiles by gas chromatography and mass spectrometry (GC-MS) has been an efficient authentication tool that allowed for the classification of the honey botanical origin (strongly related to its medici...
In this study, copolymers based on 1,3-bis(carbazol-9-yl)benzene (BCz) and three 3,4-ethylenedioxythiophene derivatives (3,4-ethylenedioxythiophene (EDOT), 3,4-(2,2-dimethylpropylenedioxy)thiophene (ProDOT-Me2), and 3,4-ethylenedithiathiophene (EDTT)...
To discover bioactive natural products from mangrove sediment-derived microbes, a chemical investigation of the two Beibu Gulf-derived fungi strains, Talaromyces sp. SCSIO 41050 and Penicillium sp. SCSIO 41411, led to the isolation of 23 natural prod...
[2 + 2 + 2] cycloaddition of a 1,2-bis(propiolyl)benzene derivative with terminal and internal alkynes takes place in the presence of [Ir(cod)Cl]2 (cod = 1,5-cyclooctadiene) combined with bis(diphenylphosphino)ethane (DPPE) to give anthraquinones in...
Microwave-assisted processing has shown tremendous promise in accelerating chemical reactions and reducing energy consumption through targeted dielectric heating. This study develops MOF-derived Mn-Co and Ce-Co oxide catalysts for energy-efficient be...
The present study reports the effective removal of benzene in aqueous phase onto biochar. The adsorption capacity of benzene onto biochars made at different pyrolytic temperatures (e.g., 350, 550, and 750 °C) and from various feedstocks (e.g., gr...
Coal tar, a by-product of the pyrolysis of coal, is rich in aromatic compounds that have the potential to facilitate the synthesis of graphene, a high-quality carbon material, via low-temperature chemical vapor deposition (CVD). This approach offers...
Microwave-assisted reaction between 2-(3-oxoindolin-2-yl)-2-phenylacetonitriles andbenzene-1,2-diamines leads to the high-yielding formation of the corresponding quinoxalines as sole, easily isolaable products. The featured transformation involves un...
A series of xylene charge-transfer complexes with fluorine-substituted tetracyanoquinodimethane (TCNQ) acceptors were studied experimentally and theoretically in order to reveal the role of various intermolecular interactions on stoichiometry and the...
There is a need to continue research to find out other anti-dermatophytic agents to inhibit causal pathogenic skin diseases including many types of tinea. We undertook the production, purification, and identification of an anti-dermatophytic substanc...
A series of novel chromophores A, B, C, and D, based on the julolidinyl donor and the tricyanofuran (TCF) and CF3-tricyanofuran (CF3-Ph-TCF) acceptors, have been synthesized and systematically investigated. The 3,5-bis(trifluoromethyl)benzene derivat...
The rapid spread of the coronavirus disease 2019 (COVID-19) resulted in serious health, social, and economic consequences. While the development of effective vaccines substantially reduced the severity of symptoms and the associated deaths, we still...
In 30 monosubstituted benzene cation radicals, studied at the ωB97XD/aug-cc-pVTZ level, the phenyl rings usually adopt a compressed form, but a differently compressed form—equivalent to an elongated one—may coexist. The computational and literature i...
A unique series of sulphonamide derivatives was attempted to be synthesized in this study using a new and effective method. All of the synthesized compounds were verified using several spectroscopic methods, including FTIR, 1H-NMR, 13C-NMR, and HREI-...
We have prepared and characterized 1,4-dibromo-2,5-bis(2-phenylethoxy)benzene (1) and 1,4-dibromo-2,5-bis(3-phenylpropoxy)benzene (2). Their single-crystal structures confirm that, at the molecular level, they are similar with the phenylalkoxy chains...
The divergence of fluorine-based systems and significance of their nascent non-covalent chemistry in molecular assemblies are presented in a brief review of the field. Emphasis has been placed to show that type-I and -II halogen-centered F·&mi...
3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol (HPN) is a bromophenol derivative from the marine red alga Rhodomela confervoides. We have previously found that HPN exerted an anti-hyperglycemic property in db/db mouse...
Lung cancer is the most frequent cause of cancer-related deaths worldwide, and mutations in the kinase domain of the epidermal growth factor receptor (EGFR) are a common cause of non-small-cell lung cancers, which is a major subtype of lung cancers....
A high-yielding click reaction was used to synthesize a series of highly conjugated, symmetrical, as well as asymmetrical compounds with a benzene core. Cyclic voltammetry and ultraviolet/visible absorption spectroscopy were carried out, and proved t...
The generation and emission of volatile organic compounds (VOCs) affects the environment and air quality, playing an important role in global warming, depletion of atmospheric ozone and emission of unpleasant odors, but also directly affect human hea...
Novel 2-amino-4-methyl-6-phenyl-benzene-1,3-dicarbonitrile derivatives were proposed as photosensitizes of iodonium salt for a highly effective bimolecular photoinitiating system upon soft irradiation conditions under long-wave ultraviolet (UV-A) and...
By taking into account our previously described series of 1,3,5-tris[(4-(substituted-aminomethyl)phenyl)methyl]benzene compounds, we have now designed, prepared, and evaluated in vitro against Plasmodium falciparum a novel series of structural analog...
Activation of C(sp2)-H in aromatic molecules such as benzene is one of the challenging reactions. The tungsten trioxide supported Pt nanoparticles (Pt-WO3) exhibited hydroxylation of benzene in the presence of air and H2O under visible-light (420 <...
Studies show that compounds such as 1,3-oxazine-6-ones are promising starting reagents that allow us to obtain various acyclic and heteroaromatic systems. These substances demonstrate a wide range of biological activity. Meanwhile, it is known that d...
Natural geranyl compounds are known to exhibit important biological activities. In this work a series of geranylphenols were synthesized to evaluate their effect on the mycelial growth of Botrytis cinerea. Geranyl derivatives were synthesized by dire...
3,4-dihydro-3-phenyl-2H-1,3-benzoxazines derived from phenol-, resorcinol-, and phloroglucinol give monomers with one, two, and three oxazine units at a single benzene ring, respectively. Aside from the synthesis and characterization of such multifun...
(E,E)-1,4-bis(4'-aminostyryl)-2,5-bis(octyloxy)-benzene (6) and its derivative (E,E)-1,4-bis(4'-acetamidostyryl)-2,5-bis(octyloxy)-benzene (7) were synthesized and characterized after alkylation, bromomethylation, Horner-Emmons reaction and reduction...
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