417 Results Found

TOM40 is a channel-forming subunit of translocase, which is essential for the movement of proteins into the mitochondria. We found that TOM40 was highly expressed in epithelial ovarian cancer (EOC) cells at both the transcriptional and translational...

The central role mitochondria play in cellular homeostasis has made its study critical to our understanding of various aspects of human health and disease. Mitochondria rely on the translocase of the outer membrane (TOM) complex for the bulk of mitoc...

In the tradition of Irish traditional music, ownership of music is vague and sometimes contested. Tunes are not generally associated with a “composer”, but, if identified with anyone at all, are generally associated with the person most w...

Tom70 is a versatile adaptor protein of 70 kDa anchored in the outer membrane of mitochondria in metazoa, fungi and amoeba. The tertiary structure was resolved for the Tom70 of yeast, showing 26 α-helices, most of them participating in the form...

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the causative agent of the COVID19 pandemic. The SARS-CoV-2 genome encodes for a small accessory protein termed Orf9b, which targets the mitochondrial outer membrane protein TOM70 in inf...

ToM (ToM) and empathy, integral components of children’s social cognitive development, are shaped by multifaceted factors. The developmental trajectories of ToM and empathy in kindergarten children have long been focal points of inquiry for res...

(1) Background: The anthropogenically induced rise in atmospheric carbon dioxide (CO2) and associated climate change are considered a potential threat to human nutrition. Indeed, an elevated CO2 concentration was associated with significant alteratio...

We present a protocol for evaluating the efficiency of an electronic white cane for improving the mobility of blind people. The electronic cane used during the test is the Tom Pouce III, made of LIDAR sensors (light detection and ranging) with tactil...

Astrocytes play a key role in brain functioning by providing energy to neurons. Increased astrocytic mitochondrial functions by Korean red ginseng extract (KRGE) have been investigated in previous studies. KRGE administration induces hypoxia-inducibl...

Salinity is a form of abiotic stress that impacts growth and development in several economically relevant crops and is a top-ranking threat to agriculture, considering the average rise in the sea level caused by global warming. Tomato is moderately s...

Early fruit development in tomato is driven by complex gene expression patterns and metabolic reprogramming, a crucial phase that shapes the fruit’s final size and structure. Previous studies using the Micro-Tom model have largely focused on la...

This article analyses the ways in which British Jewish writing has responded to the watershed events of 2016: the vote to leave the EU in the United Kingdom, and the election of Donald Trump as President of the USA. It argues that such a response dem...

Theory of mind (ToM) is a social cognitive skill that involves the ability to attribute mental states to self and others (what they think (cognitive ToM) and feel (affective ToM)). We aim to provide an overview of previous knowledge of ToM in Parkins...

In tomato (Solanum lycopersicum), there are at least three SlMLO (Mildew resistance Locus O) genes acting as susceptibility genes for the powdery mildew disease caused by Oidium neolycopersici, namely SlMLO1, SlMLO5 and SlMLO8. Of the three homologs,...

Botrytis cinerea is a devastating fungal pathogen that causes severe economic losses in global tomato cultivation. Understanding the molecular mechanisms driving tomatoes’ response to this pathogen is crucial for developing effective strategies...

This study aims to perform a broad analysis of the antioxidant (AOX) responses of young tomato plants exposed to single and combined mild nitrogen (N) and water deficits through the evaluation of oxidative biomarkers, non-enzymatic and enzymatic AOX...

Gene function analysis, molecular breeding, and the introduction of new traits in crop plants all require the development of a high-performance genetic transformation system. In numerous crops, including tomatoes, Agrobacterium-mediated genetic trans...

This paper introduces Tensor-Organized Memory (TOM), a novel neuromorphic architecture inspired by the human brain’s structural and functional principles. Utilizing spike-timing-dependent plasticity (STDP) and Hebbian rules, TOM exhibits cognit...

The aim of this study was to investigate the relationships between Theory of Mind (ToM), Working Memory (WM), and Verbal Comprehension (VC). Performance of these variables was evaluated in 44 elementary students (6–12 years) diagnosed with ADHD...

Background/Objectives: The study examined the relationships between specific Theory-of-Mind (ToM) dimensions, cognitive planning, and sleep duration in aging adults. Methods: The sample included 179 participants, comprising 46 cognitively healthy ind...

This article traces the transformation of hairworks in America during the mid-nineteenth-century. Harriet Beecher Stowe’s novel Uncle Tom’s Cabin transformed the meaning of hair and hairworks in the American cultural imaginary by endowing Little Eva...

Background/Objectives: Executive functions (EFs) and Theory of Mind (ToM) are often compromised in children with Specific Learning Disorders (SLD). Although evidence highlights the malleability of EF, studies have yet to investigate whether school-ba...

Background/Objectives: Figurative language is a central tool for enriching spoken and written languages, and it is important for building social relationships. Difficulties in figurative language understanding may impair social adjustment. Some studi...

Breast cancer is still one of the most common cancers for women. Specified therapeutics are indispensable for optimal treatment. In previous studies, it has been shown that RL2, the recombinant fragment of human κ-Casein, induces cell death in...

Indonesia has the third highest number of motorcycles, which means the traffic flow in Indonesia is heterogeneous. Traffic flow can specify its condition, whether it is a free flow or very heavy traffic. Traffic condition is the most important criter...

Recent studies deal with disorders and deficits caused by vascular syndrome in efforts for prediction and prevention. Cardiovascular health declines with age due to vascular risk factors, and this leads to an increasing risk of cognitive decline. Mil...

The translocases of the mitochondrial outer and inner membranes, the TOM and TIMs, import hundreds of nucleus-encoded proteins into mitochondria. TOM and TIMs are multi-subunit protein complexes that work in cooperation with other complexes to import...

In this study, we aim to verify how emotional training can improve empathy and theory of mind (ToM) in patients diagnosed with early onset schizophrenia and Asperger’s syndrome. The study design includes 100 subjects divided into two experiment...

Metabolite carriers of the mitochondrial inner membrane are crucial for cellular physiology since mitochondria contribute essential metabolic reactions and synthesize the majority of the cellular ATP. Like almost all mitochondrial proteins, carriers...

The paper reads Stoppard’s work in the 21st century as further testimony of the gradual politicisation of his work that began in the 1970s under the influence of Czech dissidents, and particularly as a result of his visits to Russia and Prague in 197...

Background: In this systematic review, conducted according to the PRISMA 2020 guidelines, we aimed to assess differences in the cognitive processes associated with social cognition—namely language, theory of mind (ToM), and executive functions...

Four synoptic regimes were identified as accompanying the widespread dust in central and eastern Saudi Arabia. The widespread cases of dust were classified based on the value and spread of the aerosol index data from the TOMS aerosol index (TOMS AI)...

This study examines the link between language abilities and Theory of Mind (ToM) development in individuals with Williams Syndrome (WS) and Down Syndrome (DS). We compared the results of 16 participants with WS, aged 6.3 to 27.2 years (Mean = 15.9 ye...

For some time now, regardless of the still-common paradigm of Barbour’s practice of science–religion relations, proposals have been emerging to develop a theology of science from a Christian perspective. This article begins by discussing...

A stepwise multi regression-based statistics was employed for prioritizing the influence of several factors, anthropogenic and/or natural, on the ERA15 temperature increments. The 5 factors that are defined as predictors are: topography, aerosol ind...

Mitochondria import about 1000 precursor proteins from the cytosol. The translocase of the outer membrane (TOM complex) forms the major entry site for precursor proteins. Subsequently, membrane-bound protein translocases sort the precursor proteins i...

The sequence of the process of changing the velocity profiles and the laws of resistance during the flow of a fluid in a pipe is considered. With the increasing of the Reynolds number, we obtain the transition of the flow regime from laminar to turbu...

It is now common to blame Christianity for broader society’s general inattention to the needs and comfort of animals in general, and farmed animals in particular. This critique of Christianity claims that certain biblical themes and particular...

Thinning of the atmospheric ozone layer leads to elevated levels of Ultraviolet-B (UVB) at the Earth's surface, resulting in an increase of health risks to living organisms due to DNA damage. This paper examines the multidecadal changes of total colu...

This work aims to evaluate how a temporary school square implemented in the city of Bologna under the principles of the tactical urbanism approach impacted on vehicular patterns through exploiting TomTom Floating Car Data (FCD) from before and after...

Control methods are applied worldwide to reduce predation on livestock by European red foxes (Vulpes vulpes). Lethal methods can inflict suffering; however, moral debate about their use is lacking. Non-lethal methods can also inflict suffering and ca...

This paper follows an integrated approach of Internet of Things based sensing and machine learning for crop growth prediction in agriculture. A Dynamic Bayesian Network (DBN) relates crop growth associated measurement data to environmental control da...

Mitochondria are essential in eukaryotes. Besides producing 80% of total cellular ATP, mitochondria are involved in various cellular functions such as apoptosis, inflammation, innate immunity, stress tolerance, and Ca2+ homeostasis. Mitochondria are...

The endophytic fungi Serendipita indica and S. vermifera have recently gained increasing attention due to their beneficial effects on plant growth and plant health. Little is known about other species, such as S. williamsii and S. herbamans. To test...

Light quality affects plant growth and the functional component accumulation of fruits. However, there is little knowledge of the effects of light quality based on multiomics profiles. This study combined transcriptomic, ionomic, and metabolomic anal...

To date, the largest Russian rivers discharging to the Arctic Ocean remain a “blank spot” on the world map of data on the distribution of microplastics in freshwater systems. This study characterizes the abundance and morphology of microp...

In only around 40% of families with pulmonary fibrosis (PF) a suspected genetic cause can be found. Genetic overlap analysis of Whole Exome Sequencing (WES) data may be a powerful tool to discover new shared variants in novel genes for PF. As a proof...

The objective of this work is to analyze the temporal and spatial variability of the total ozone column (TOC) trends over the Yangtze River Delta, the most populated region in China, during the last 35 years (1978–2013) using remote sensing-derived T...

Fertilization is essential for the optimal growth and development of crops; however, the amount of fertilizer can cause positive or negative effects depending on its rate. In addition, the cultivation system plays a significant role in determining ve...

The accuracy and speed of tomato detection were increased to facilitate fully automated harvesting by improving the Real-Time Detection Transformer (RTDETR) to develop a new lightweight tomato detection model called LiteTom-RTDETR. This model employe...