A Multi-Resolution Weakly Compressible Moving-Particle Semi-Implicit (MR-WC-MPS) method is presented in this paper for simulation of free-surface flows. To reduce the computational costs, as with the multi-grid schemes used in mesh-based methods, the...
Microphysiological systems (MPS) are an emerging technology for next-generation drug screening in non-clinical tests. Microphysiological systems are microfluidic devices that reconstitute the physiological functions of a human organ using a three-dim...
This work aims to propose an efficient MPS/FEM coupling method for the simulation of fluid–structure interaction (FSI), where the MPS and FEM are respectively employed to account for fluid flows and structural deformation. The main idea of our...
Magnetic particle spectroscopy (MPS) in the Brownian relaxation regime, also termed magnetic spectroscopy of Brownian motion (MSB), can detect and quantitate very low, sub-nanomolar concentrations of molecular biomarkers. MPS/MSB uses the harmonics o...
Mucopolysaccharidosis I-Hurler (MPS I-H) is caused by the loss of α-L-iduronidase, a lysosomal enzyme that degrades glycosaminoglycans. Current therapies cannot treat many MPS I-H manifestations. In this study, triamterene, an FDA-approved, ant...
Microhaplotypes (MHs) are widely accepted as powerful markers in forensic studies. They have the advantage of both short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs), with no stutter and amplification bias, short fragments and amp...
Pervasive microplastics (MPs) and per- and polyfluoroalkyl substances (PFAS) frequently co-occur across aquatic and terrestrial environments due to shared sources, transport pathways, and persistence, yet their interaction-driven effects on environme...
The advent of the COVID-19 era has ushered in significant changes to both the environment and daily life. During the COVID-19 lockdown, a unique opportunity emerged to improve environmental quality and mitigate certain impacts on the planet. The dist...
As a Lagrangian mesh-free method, the moving particle semi-implicit (MPS) method can easily handle complex incompressible flow with a free surface. However, some deficiencies of the MPS method, such as inaccurate results, unphysical pressure oscillat...
Mucopolysaccharidosis (MPS) type I and II are two closely related lysosomal storage diseases associated with disrupted glycosaminoglycan catabolism. In MPS II, the first step of degradation of heparan sulfate (HS) and dermatan sulfate (DS) is blocked...
Forensic DNA phenotyping (FDP) provides the ability to predict the human external traits from unknown sample donors, directly from minute amounts of DNA found at the crime scene. We developed a MPS multiplex assay, with the aim of genotyping all 41 D...
To test the usefulness of the forensic PCR-MPS approach to eye and hair color prediction for aged skeletons, a customized version of the PCR-MPS HIrisPlex panel was used on two sets of samples. The first set contained 11 skeletons dated from the 3rd...
Floodwater entering the damaged cabin and impacting the bulkhead can cause damage to the watertight compartment and affect the survival of the ship. The elastic deformation of the bulkhead can slow down the impact and affect the flow field, which aff...
This paper demonstrated the impact of process conditions on the surge current capability of 1.2 kV SiC junction barrier Schottky diode (JBS) and merged PiN Schottky diode (MPS). The influence of ohmic contact and defect density produced by implantati...
Continental delta deposits are characterized by strong heterogeneity in the lateral direction; meanwhile, reservoir development is challenged by rapid changes in rock properties. Thus, it is critical to use proper methods for fine characterization to...
A novel magnetic fluorescent nanoprobe (Fe3O4@ZnS@MPS(MFNPs)) was synthesized, which recognized and cooperated with Ag+ ions, and a rapid method for detecting Ag+ was established in solution. It was found by fluorescence spectroscopy analysis that th...
Liquid sloshing in ship tanks would have a direct effect on ship dynamic stability, and thus is of great importance for navigation safety. To calculate the sloshing-induced force on real ship tanks, this paper presents an approach to numerically simu...
Mucopolysaccharidosis type II (MPS-II, Hunter syndrome, OMIM:30990) is a lysosomal storage disorder (LSD) that results in iduronate 2-sulphatase (I2S) enzyme deficiency. MPS-II was added to the Recommended Uniform Screening Panel (RUSP) in August 202...
The mucopolysaccharidoses (MPS), Pompe Disease (PD), and Krabbe disease (KD) are inherited conditions known as lysosomal storage disorders (LSDs) The resulting enzyme deficiencies give rise to progressive symptoms. The United States Department of Hea...
Here, we present the molecular diagnosis of a patient with a general clinical suspicion of Mucopolysaccharidosis, highlighting the different tools used to perform its molecular characterization. In order to decrease the turnaround time for the final...
Genetically encoded calcium indicators (GECIs) have become a widespread tool for the visualization of neuronal activity. As compared to popular GCaMP GECIs, the FGCaMP indicator benefits from calmodulin and M13-peptide from the fungi Aspergillus nige...
The family of MOBs (monopolar spindle-one-binder proteins) is highly conserved in the eukaryotic kingdom. MOBs represent globular scaffold proteins without any known enzymatic activities. They can act as signal transducers in essential intracellular...
New characterizations of the gMP inverse are provided by the core part of the core-EP decomposition. We also answer the question as to whether X is the gMP inverse of A under the conditions of R(X)⊆R(A*Ak) or N((Ak)*)⊆N(X). We investigate t...
In this paper, we consider a non-orthogonal multiple access (NOMA) system with coordinated multi-point (CoMP), which is used in 5G cellular networks to guarantee the rate requirements from the different edge users. Based on the China Family Panel Stu...
The kidney proximal tubule (PT) mediates renal drug elimination in vivo and is a major site of drug-induced toxicity. To reliably assess drug efficacy, it is crucial to construct a model in which PT functions are replicated. Current animal studies ha...
This effort describes a low-power analog MP3 psychoacoustic model designed, implemented, and demonstrated using a large-scale Field-Programmable Analog Array (FPAA) to allocate bits for MP3 compression. Although MP3 encoders are assumed to be a digit...
With the growth of Internet of Things (IoT) services and applications, the efficient transmission of IoT data has been crucially required. The IETF has recently developed the QUIC protocol for UDP-based multiplexed and secure transport. The Multipath...
Mucopolysaccharidoses (MPS) are the group of lysosomal storage disorders caused by deficiencies of enzymes involved in the stepwise degradation of glycosaminoglycans. To identify brain pathology common for neurological MPS, we conducted a comprehensi...
When dealing with the complex deformation of free surface such as wave breaking, traditional mesh-based Computational Fluid Dynamics (CFD) methods often face problems arising alongside grid distortion and re-meshing. Therefore, the meshless method be...
Monocrystalline silicon, despite its widespread use as a photoelectrode material, is hindered by inherent drawbacks, such as high surface reflectivity, vulnerability to oxide passivation, and instability in aqueous electrolytes. To address these, a m...
Mono-polar spindle 1 (Mps1/TTK) represents a protein kinase reported to be vital for cell division processes and is generally regarded as an attractive target for the treatment of hepatocellular carcinoma, breast carcinoma, and colon cancer. However,...
In order to accurately and efficiently analyze the distribution law and motion status of lubricating oil in the spiral bevel gearbox of the electric multiple unit (EMU), a high-fidelity 3D CFD model of the spiral bevel gearbox of the EMU was establis...
Background: Micropeptides, encoded by non-coding RNAs, play a pivotal role in various cellular functions. While several micropeptides have already been linked to HCC, their roles remain incompletely understood. Our study identifies MP60, a conserved...
Red fluorescent genetically encoded calcium indicators (GECIs) have expanded the available pallet of colors used for the visualization of neuronal calcium activity in vivo. However, their calcium-binding domain is restricted by calmodulin from metazo...
Multipath transport protocols have the ability to simultaneously utilize the different paths and thus outperform single-path solutions in terms of achievable goodput, latency, or reliability. In this paper our goal is to examine the potential of conn...
Viruses are one of the leading causes of human disease, and many highly pathogenic viruses still have no specific treatment drugs. Therefore, producing new antiviral drugs is an urgent matter. In our study, we first found that the natural wasp venom...
Satellite communications are pivotal to global Internet access, connectivity, and the advancement of information warfare. Despite these importance, the open nature of satellite channels makes them vulnerable to eavesdropping, making the enhancement o...
With the increase in user density, it is a challenging problem to achieve higher energy efficiency in vehicle-to-everything (V2X) networks, where frequent handovers occur as users continuously pass through dense cell boundaries. In this paper, we inv...
Prostate cancer is the second most common cancer in men and a leading cause of death worldwide. Early detection is vital, as it often presents with vague symptoms such as nocturia and poor urinary stream. Diagnostic tools like PSA tests, ultrasound,...
Mastoparans from the venom of social wasps have attracted considerable attention as effective antibiotic candidates. In this study, mastoparan V1 (MP-V1) from Vespula vulgaris was first disclosed to have a peptide amino acid sequence distinct from ty...
The huge traffic demand envisioned in 5G requires radical changes in mobile network architecture. A Centralized Radio Access Network (C-RAN) was introduced as a novel mobile network architecture, designed to effectively support the challenging requir...
Since each branch of the multiterminal DC circuit system relies on the DC circuit breaker for breaking and fault isolation, the prohibitive cost and huge volume of the Hybrid DC Circuit Breaker (HCB) limit its development and broad application in mul...
Eliminating noise signals of the magnetotelluric (MT) method is bound to improve the quality of MT data. However, existing de-noising methods are designed for use in whole MT data sets, causing the loss of low-frequency information and severe mutatio...
In the context of the COVID-19 global epidemic, it is particularly important to use limited medical resources to improve the systemic control of infectious diseases. There is a situation where a shortage of medical resources and an uneven distributio...
Green fluorescent genetically encoded calcium indicators (GECIs) are the most popular tool for visualization of calcium dynamics in vivo. However, most of them are based on the EGFP protein and have similar molecular brightnesses. The NTnC indicator,...
In this study, a real-time volcanic ash plume prediction by the PUFF system was applied to the Sakurajima volcano (which erupted at 17:24 Japan Standard Time (JST) on 8 November 2019), using the direct observation of the multi-parameter (MP) radar da...
Research on two dimensional (2D) antiferromagnetic materials and heterobilayers is gaining prominence in spintronics. This study focuses on MPS3 monolayers and their van der Waals heterobilayers with GaN monolayers. We systematically investigated the...
Prostate carcinoma is one of the most prevalent cancers worldwide. Multiparametric magnetic resonance imaging (mpMRI) is a non-invasive tool that can improve prostate lesion detection, classification, and volume quantification. Machine learning (ML),...
Newborn screening enables the diagnosis of treatable disorders at the early stages, and because of its countless benefits, conditions have been continuously added to screening panels, allowing early intervention, aiming for the prevention of irrevers...
As new pollutants, microplastics (MPs) have attracted much attention worldwide because they cause serious environmental pollution and pose potential health risks to humans. However, the toxic effects of MPs are still unclear. In this study, we analys...
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