Content Delivery Network (CDN) technology is one of the core technologies for performance optimization of mobile WEB applications, but it often encounters bottlenecks in video storage. In this paper, based on studying the basic technical model of dis...
Immune checkpoint inhibitors (ICI) have revolutionised cancer therapy. However, they have been effective in only a small subset of patients and a principal mechanism underlying immune-refractoriness is a ‘cold’ tumour microenvironment, th...
This paper formulates and solves a new problem of the double model following adaptive control (MFAC) of nodes and links in a complex dynamical network (CDN). This is different from most existing studies on CDN and MFAC. Inspired by the concept of com...
Drugs are widely used as therapeutic agents; however, they may present some limitations. To overcome some of the therapeutic disadvantages of drugs, the use of β-cyclodextrin-based nanosponges (βCDNS) constitutes a promising strategy. βCDNS are matri...
A wide range of analytical techniques have been reported to determine cordycepin (CDN) in various sample matrices. Nevertheless, greener analytical approaches for CDN estimation are scarce in the literature. As a result, this study was designed to de...
As prophylactic vaccine adjuvants for infectious diseases, cyclic dinucleotides (CDNs) induce safe, potent, long-lasting humoral and cellular memory responses in the systemic and mucosal compartments. As therapeutic cancer vaccine adjuvants, CDNs ind...
Cyclic dinucleotides (CDNs), originally discovered as bacterial second messengers, play critical roles in bacterial signal transduction, cellular processes, biofilm formation, and virulence. The finding that CDNs can trigger the innate immune respons...
The scope of complex dynamical networks (CDNs) with dynamic edges is very wide, as it is composed of a class of realistic networks including web-winding systems, communication networks, neural networks, etc. However, a classic research topic in CDNs,...
The regulation of multiple bacterial phenotypes was found to depend on different cyclic dinucleotides (CDNs) that constitute intracellular signaling second messenger systems. Most notably, c-di-GMP, along with proteins related to its synthesis, sensi...
Stimulator of interferon genes (STING) is an endoplasmic reticulum adaptor transmembrane protein that plays a pivotal role in innate immune system. STING agonists, such as endogenous cyclic dinucleotide (CDN) cyclic GMP-AMP (cGAMP), have been used in...
In today’s digital landscape, content delivery networks (CDNs) play a pivotal role in ensuring rapid and seamless access to online content across the globe. By strategically deploying a network of edge servers in close proximity to users, CDNs...
The allosteric SERCA (Sarcoplasmic/Endoplasmic Reticulum Ca2+-ATPase) activator CDN1163 has been recently added to the group of pharmacological tools for probing SERCA function. We chose to investigate the effects of the compound on T lymphocyte Ca2+...
Stimulator of Interferon Genes (STING) is a type of endoplasmic reticulum (ER)-membrane receptor. STING is activated by a ligand binding, which leads to an enhancement of the immune-system response. Therefore, a STING ligand can be used to regulate t...
Content Delivery Networks (CDNs) have evolved to meet surging data demands and stringent low-latency requirements driven by emerging applications like high-definition video streaming, virtual reality, and IoT. This paper proposes a hybrid CDN archite...
This paper aims to investigate the robustness of exponential synchronization in complex dynamic networks (CDNs) with time-varying delays and random disturbances. Via the Gronwall–Bellman lemma and partial inequality methods, by calculating the...
Satellite-enabled content delivery networks (S-CDNs) are needed to improve content access for wide-area, remote, and highly dynamic users, for whom relying only on terrestrial CDN infrastructure is often insufficient. However, in conventional CDN sys...
mRNA-based vaccines against the COVID-19 pandemic have propelled the use of nucleic acids for drug delivery. Conventional lipid-based carriers, such as liposomes and nanolipogels, effectively encapsulate and deliver RNA but are hindered by issues suc...
With the explosive growth of the demand for computing power in the era of digital economy and the continuous enhancement of the computing power of terminals, how to provide high bandwidth, low-latency, and low-cost service by leveraging the user devi...
This paper is concerned with the secure and resource-efficient cluster synchronization problem of a class of complex dynamical networks (CDNs) under random deception attacks. Each node in the CDNs is modeled by a nonlinear dynamical system with multi...
Cyclodextrin-based nanosponges (CDNSs) are novel polymers composed of cross-linked cyclodextrin (CD) macrocyclic units, whose characteristics make them great candidates for drug delivery systems with adjustable properties for the drug release process...
This paper investigates the problem of exponential synchronization control for complex dynamical systems (CDNs) with input saturation. Considering the effects of transmission delay, a memory sampled-data controller is designed. A modified two-sided l...
In attempt to broaden the use of cyclodextrin polymer for catalytic purposes, a novel covalent hybrid system was prepared through growth of multi-nitrogen atom containing polymer (PMelamine) derived from reaction of ethylenediamine and 2,4,6-trichlor...
Illegal broadcasting is one of the primary challenges for Over the Top (OTT) service providers. Watermarking is a method used to trace illegal redistribution of video content. However, watermarking introduces processing overhead due to the embedding...
7 September 2022
Phosphorus treatment can reduce Cd accumulation and Cd toxicity in rice, but alterations in the internal regulatory network of rice during this process have rarely been reported. We have removed the effect of cadmium phosphate precipitation from the...
Multiagent cooperation is one of the most attractive research fields in multiagent systems. There are many attempts made by researchers in this field to promote cooperation behavior. However, several issues still exist, such as complex interactions a...
Stimulator of interferon genes (STING) agonists can improve the anticancer efficacy of immune checkpoint blockade by amplifying tumor immunogenicity. However, the clinical translation of cyclic dinucleotides (CDNs) as STING agonists is hindered by th...
In the trend of transforming existing systems and services into non-face-to-face models, the concert industry is also showing movements toward transitioning to virtual formats. Physical concerts in the real world require venues that can accommodate h...
Redirection and protocol techniques are key components of the infrastructure for Content Delivery Networks (CDNs) that aid in the delivery of Multimedia Internet services to end-consumers. Redirection methods are used to route the user’s reques...
In this paper, we propose subcarrier allocation based cooperative spectrum sharing protocol for OFDM relaying networks with wireless energy harvesting. In the proposed protocol, the cognitive relay node utilizes different subcarriers to forward the p...
In the present research, a sonochemical approach was applied to prepare new cadmium(II) coordination 2D polymer, [Cd(L)(NO2)2]n (L = 1,2-bis(1-(pyridin-3-yl)ethylidene)hydrazine) and structurally characterized with various spectroscopic techniques in...
Cyclodextrin-based nanosponges (CDNSs) are complex macromolecular structures composed of individual cyclodextrins (CDs) and nanochannels created between cross-linked CD units and cross-linkers. Due to their unique structural and physicochemical prope...
Satellite altimetry provides exceptional means for absolute and undisputable monitoring of changes in sea level and inland waters (rivers and lakes), over regional to global scales, with accuracy and with respect to the center of mass of the Earth. A...
Distributed appliances connected to the Internet have provided various multimedia services. In particular, networked Personal Video Recorders (PVRs) can store broadcast TV programs in their storage devices or receive them from central servers, enabli...
Induction of immunoglobulin (Ig) A in the mucosa of the upper respiratory tract and the nasal cavity protects against influenza virus infection. Cyclic dinucleotides (CDNs) are used as mucosal adjuvants to enhance the immunogenicity of intranasal inf...
Video delivery is exploiting 5G networks to enable higher server consolidation and deployment flexibility. Performance optimization is also a key target in such network systems. We present a multi-objective optimization framework for service function...
The transmission bandwidth of a vehicle–ground connection is low when an EMU (electric multiple unit) is running in a high-speed scenario. To this end, this paper focuses on the need to solve the problem of the poor bandwidth of the vehicle&nda...
Quantum computing threatens the security foundations of global financial systems, exposing long-lived data and signed digital assets to “harvest-now, decrypt-later” attacks. While the timeline for cryptographically relevant quantum comput...
The demand for multimedia content over the Internet protocol network is growing exponentially with Internet users’ growth. Despite high reliability and well-defined infrastructure for Internet protocol communication, Quality of Experience (QoE) is th...
This paper addresses the problem of fixed-time consensus tracking for a class of nonlinear multiagent systems (MASs) with disturbances. We establish a novel fixed-time consensus tracking protocol with adaptive disturbance rejection capabilities, leve...
Malicious domains are part of the landscape of the internet but are becoming more prevalent and more dangerous both to companies and to individuals. They can be hosted on various technologies and serve an array of content, including malware, command...
Underdeveloped immunity during the neonatal age makes this period one of the most dangerous during the human lifespan, with infection-related mortality being one of the highest of all age groups. It is also discussed that vaccination during this time...