- Article
Bag-1 Protects Nucleus Pulposus Cells from Oxidative Stress by Interacting with HSP70
- Kaori Suyama,
- Daisuke Sakai,
- Shogo Hayashi,
- Ning Qu,
- Hayato Terayama,
- Daisuke Kiyoshima,
- Kenta Nagahori and
- Masahiko Watanabe
Bcl-2-associated athanogene 1 (Bag-1) is a multifunctional prosurvival protein that binds to several intracellular targets and promotes cell survival. HSP70 and Raf-1 are important targets of Bag-1; however, the protective function of Bag-1 in nucleu...