Many methods for evaluating the aquifer’s vulnerability to pollution have been developed in the past four decades by using geographic information system (GIS) tools. However, even if the aquifer vulnerability concept is well defined and the met...
The dynamics of power systems is often analyzed using real-time simulators. The basic requirements of these simulators are the speed of obtaining the results and their accuracy. Known algorithms (backward Euler or trapezoidal rule) used in real-time...
In this paper, testing and diagnosis methods for the static excitation systems of power plant synchronous generators using Hardware-In-the-Loop technology are described. These methods allow a physical excitation system to be connected to a real-time...
Individual taste sensitivity influences food preferences, nutritional control, and health, and differs greatly between individuals. The purpose of this study was to establish a method of measuring and quantifying an individual’s taste sensitivi...
Introduction: Patients with end-stage kidney disease (ESRD) represent a high-risk population in terms of both development of and death by cardiovascular diseases. Outcome data of ESRD patients with severe aortic valve stenosis (AS) treated by transca...
The siderophore–antibiotic conjugate LCB10-0200 (a.k.a. GT-1) has been developed to combat multidrug-resistant Gram-negative bacteria. In this study, the in vitro activity of LCB10-0200 and LCB10-0200/avibactam (AVI) has been investigated against car...
Purpose: To evaluate the real-world evidence of ceftazidime-avibactam (CAZ-AVI) compared to intravenous colistin for the treatment of multidrug-resistant (MDR) P. aeruginosa infections. Method: This is a multicenter, retrospective cohort study conduc...
Background: Ceftazidime-Avibactam (CAZ-AVI) is one of the new antibiotics available to treat infections due to carbapenem-resistant gram-negative bacteria (CRB). Our aim was to describe the use of CAZ-AVI in children admitted to pediatric intensive c...
Background: Ceftazidime/avibactam (CAZ-AVI) resistance amongst Enterobacterales is worryingly increasing worldwide. Objectives: The aim of this study was to collect and describe real-life data on CAZ-AVI-resistant Klebsiella pneumoniae (KP) isolates...
Background: Ceftazidime–avibactam (CAZ-AVI) is recommended as first-line treatment for Oxacillinase-48 (OXA-48) β-Lactamase-producing carbapenem-resistant Enterobacterales (CRE) infections, while polymyxin-based combination therapies (PBCT...
Background/objectives: Infections caused by carbapenem-resistant Enterobacterales (CRE) are progressively increasing in Pediatric Intensive Care Units (PICUs). Its treatment is challenging due to the lack of pediatric trials. CRE infections are assoc...
Background/Objectives: Metallo-β-lactamase (MBL)-producing Gram-negative bacteria represent a growing global health threat due to their broad resistance to β-lactam antibiotics, including carbapenems, which severely limits treatment options...
The novel β-lactam/β-lactamase inhibitor combinations (βL-βLICs) are one of the last-line resources available against multidrug-resistant (MDR) Gram-negative bacteria. Among βL-βLICs, ceftazidime/avibactam (CAZ-AVI) demo...
Background: Antibiotic resistance represents a growing concern. A new strategy developed to treat severe infections is represented by ceftazidime/avibactam (CZA/AVI). Despite the promising activities against more pathogens, continuous monitoring is r...
Monitoring vehicles’ paths is important for the management and governance of smart sustainable cities, where traffic sensors play a significant role. As a typical sensor, an automatic vehicle identification (AVI) sensor can observe the whereabo...
Introduction, objectives: Obesity is a global health problem with a great negative impact on health. Among the pathologies caused by obesity are insulin resistance and metabolic syndrome, which constitute an increasingly common health problem in both...
Background: The Arterial Velocity Pulse Index (AVI) and Arterial Pressure–Volume Index (API) are novel non-invasive indices of arterial stiffness derived from cuff-oscillometric measurements. Previous studies have shown that elevated AVI and AP...
Background: A novel fixed combination of aztreonam (ATM) and avibactam (AVI) offers promising potential to treat infections with carbapenem-resistant Enterobacterales (CRE) producing metallo-β-lactamases (MBL). This study aimed to assess the acc...
Background/Objectives: Antimicrobial resistance (AMR) has increased significantly over the years, contributing to a real challenge in the intensive care unit (ICU). The emergence of metallo-beta-lactamases (MBLs) has contributed to the protection of...
Background: Carbapenemase-producing Klebsiella pneumoniae (CP-KP) represents a global threat to public health, with limited antimicrobial therapeutic options. In this study, we analyzed a ceftazidime/avibactam (CAZ-AVI)-resistant K. pneumoniae isolat...
Background: Evidence has shown that short courses of antibiotic therapy are at least as effective as long courses with better clinical outcomes. CAZ/AVI has demonstrated its clinical efficacy in treating K. pneumoniae-KPC infections. Methods: We cond...
Background: Recently, the arterial velocity pulse index (AVI) and arterial pressure volume index (API) have been used to evaluate arterial stiffness and endothelial function. As arterial stiffness and endothelial injury are risk factors for coronary...
In islanded operation, precise power sharing is an immensely critical challenge when there are different line impedance values among the different-rated inverters connected to the same electrical network. Issues in power sharing and voltage compensat...
Background/Introduction: Carbapenem-resistant Klebsiella pneumoniae (CRKP) bacteremia is a serious public health problem due to its high mortality rate and limited treatment options. This study aimed to identify risk factors associated with ceftazidi...
Background: This study aimed to compare mortality rates and treatment efficacy between ceftazidime–avibactam (CAZ/AVI) and meropenem-based combination regimens in critically ill patients with carbapenem-resistant Gram-negative bacteria (CRGNB)...
Ceftazidime–avibactam (CAZ-AVI) is a second-generation intravenous β-lactam/β-lactamase inhibitor combination. In recent years, substantial evidence has emerged regarding the efficacy and safety of CAZ-AVI. However, data on its use in...
Background: Aortic valve infective endocarditis (AV-IE) and mitral valve infective endocarditis (MV-IE) are often grouped together as one entity: left-sided endocarditis. However, there are significant differences between the valves in terms of anato...
Salmonellosis is a global food safety challenge caused by Salmonella, a gram-negative bacterium of zoonotic importance. Poultry is considered a major reservoir for the pathogen, and humans are exposed through consumption of raw or undercooked product...
Background/Objectives: Metallo-β-lactamases (MBLs) in Enterobacterales and other Gram-negative organisms pose significant public health threats due to their association with multidrug resistance (MDR). Although aztreonam (AZT) can target MBL-pro...
To implement fine-grained progression signal control on arterial, it is essential to have access to the time-varying distribution of the origin–destination (OD) flow of the arterial. However, due to the sparsity of automatic vehicle identificat...
Introduction: New anthropometric indices have been developed as an alternative to body mass index (BMI) and waist circumference (WC) to assess body mass and visceral fat. Asymptomatic hyperuricemia is considered an independent cardiovascular risk fac...
Objectives: The aim of this study was to describe our experience of a combination treatment including meropenem/vaborbactam (M/V) plus aztreonam (ATM) for bloodstream infections (BSIs) due to ceftazidime/avibactam-resistant Klebsiella pneumoniae (CAZ...
Background/Objectives: Arterial stiffness is an independent cardiovascular risk factor, and arterial velocity pulse index (AVI) and arterial pressure–volume index (API) are practical oscillometric markers. Shigin, a traditional Japanese vocal r...
The main issue in this paper is the real-time simulator of a part of a power grid with a wind turbine. The simulator is constructed on the basis of a classic PC running under a classic operating system. The proposed solution is expected and desired b...
Background/Objectives: Bloodstream infections (BSIs) caused by carbapenem-resistant Enterobacterales (CREs) are a growing public health threat due to limited therapeutic options and high mortality. In Turkey, oxacillinase-48 (OXA-48) producers predom...
Population growth, increasing urbanization and industrialization, mismanagement, and climate change are accountable for the rising depletion and pollution of groundwater worldwide. Consequently, water security, food security, and environmental securi...
Background: Although ceftazidime/avibactam (CAZ/AVI) has become an important option for treating adults and children, no data or recommendations exist for neonates. We report a neonatal sepsis case due to CAZ/AVI-resistant blaKPC-2-harboring Klebsiel...
The challenge of small data has emerged in synthetic aperture radar automatic target recognition (SAR-ATR) problems. Most SAR-ATR methods are data-driven and require a lot of training data that are expensive to collect. To address this challenge, we...
Background: The combination of aztreonam (ATM) and avibactam (AVI) presents an important therapeutic option for carbapenem-resistant Enterobacterales, particularly the NDM-producing Enterobacterales. In 2024, both the CLSI and EUCAST published their...
Introduction: The combination of ceftazidime−avibactam (CAZ-AVI) with aztreonam (ATM) may be an option for the treatment of infections due to metallo-β-lactamases (MBLs) producing bacteria, as recommended by current guidelines. MBLs protec...
A murine model of myelofibrosis in tibia was used in a co-clinical trial to evaluate segmentation methods for application of image-based biomarkers to assess disease status. The dataset (32 mice with 157 3D MRI scans including 49 test–retest pa...
Seabed sediment predictions at regional and national scales in Australia are mainly based on bathymetry-related variables due to the lack of backscatter-derived data. In this study, we applied random forests (RFs), hybrid methods of RF and geostatist...
Background: Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality, despite advances in treatment. Early detection of vascular aging is critical, as preclinical atherosclerosis often remains undiagnosed. AI-determined vascul...
Air emissions from livestock farming, particularly ammonia (NH3) and particulate matter (PM2.5 and PM10), constitute a major environmental and occupational health concern. The aim of this work was to assess the compliance with the Verification of Env...
The gene TAS2R38 single nucleotide polymorphisms (SNPs-P49A, A262V and V296I) can condition bitter tasting by PAV (proline–alanine–valine) and non-bitter-tasting by AVI (alanine–valine–isoleucine) homozygosity. We evaluated th...
Introduction: Gram-negative bacteria (GNB) account for about 70% of infections in the intensive care unit (ICU) setting and are associated with significant morbidity and mortality. In recent years, pan-drug resistant (PDR) strains, strains that are n...
This work deals with the Traffic State Estimation (TSE) problem for urban networks, using heterogeneous sources of data such as stationary flow sensors, Floating Car Data (FCD), and Automatic Vehicle Identifiers (AVI). A data-based flow and density e...
For spray applications, drop size is the most important feature as it affects all aspects of a phytosanitary treatment: biological efficacy, environmental pollution, and operator safety. In turn, drop size distribution depends on nozzle type, liquid...
Objectives: The aim of this study was to assess the distribution of abdominal volume index (AVI) conicity index (C-Index) and weight adjusted waist index (WWI) attributes by sociodemographic and health characteristics in apparently healthy individual...
This study was conducted in the Harran Plain within the framework of the Southeastern Anatolia Project (GAP) in Türkiye to evaluate the vulnerability of groundwater to contamination, with a special emphasis on the high salinity conditions attrib...
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