Sediment transport and shoreline changes causing shoreline morphodynamic evolution are key indicators of a coastal structure’s operational continuity. To reduce the computational costs associated with sediment transport modelling tools, a novel...
Type 10 17β-hydroxysteroid dehydrogenase (17β-HSD10) is the HSD17B10 gene product. It plays an appreciable part in the carcinogenesis and pathogenesis of neurodegeneration, such as Alzheimer’s disease and infantile neurodegeneration....
Type 10 17β-hydroxysteroid dehydrogenase (17β-HSD10) is the HSD17B10 gene product playing an appreciable role in cognitive functions. It is the main hub of exercise-upregulated mitochondrial proteins and is involved in a variety of metaboli...
It has long been established that mitochondrial dysfunction in Alzheimer’s disease (AD) patients can trigger pathological changes in cell metabolism by altering metabolic enzymes such as the mitochondrial 17β-hydroxysteroid dehydrogenase t...
Type 10 17β-hydroxysteroid dehydrogenase (17β-HSD10), a homo-tetrameric multifunctional protein with 1044 residues encoded by the HSD17B10 gene, is necessary for brain cognitive function. Missense mutations result in infantile neurodegenera...
Human 17β-hydroxysteroid dehydrogenase type 10 is a multifunctional protein involved in many enzymatic and structural processes within mitochondria. This enzyme was suggested to be involved in several neurological diseases, e.g., mental retardat...
The dimensionless Leaf Area Index (LAI) is widely used to characterize vegetation cover. With recent remote sensing developments LAI is available for large areas, although not continuous. However, in practice, continuous spatial-temporal LAI datasets...
In this work, we developed a software tool for the simplified, automated definition and viewing of loci in the plane, an essential task in the design, engineering and architectural fields. The process was started by identifying the most salient geome...
In the original publication [...]
Highly active antiretroviral therapy (HAART) includes very potent drugs that are often characterized by high toxicity. Tenofovir (TFV) is a widely used drug prescribed mainly for pre-exposure prophylaxis (PreP) and the treatment of human immunodefici...
The research community has made significant advances towards realizing self-tuning cloud caches; notwithstanding, existing products still require manual expert tuning to maximize performance. Cloud (software) caches are built to swiftly serve request...
An in vitro study evaluated the fracture resistance of four CAD/CAM restorative materials: lithium disilicate ceramic (IPS e.max CAD, EM), hybrid ceramic (Vita Enamic, VE), a polymer-based composite (Cerasmart, CS), and a novel 3D-printed resin (Cera...
This article presents evidence of the convenience of implementing the geometric places of the plane into commercial computer-aided design (CAD) software as auxiliary tools in the computer-aided sketching process. Additionally, the research considers...
Appropriate hapten design and synthesis have been identified as critical steps to generate high-performance immunoreagents and to develop sensitive and selective immunoanalytical methods. Antibodies and immunoassays for the major mycotoxin zearalenon...
Immunochemical methods for mycotoxin analysis require antigens with well-defined structures and antibodies with outstanding binding properties. Immunoreagents for the mycotoxins alternariol and/or alternariol monomethyl ether have typically been obta...
The excessive deposition of abdominal fat has become an important factor in restricting the production efficiency of chickens, so reducing abdominal fat deposition is important for improving growth rate. It has been proven that miRNAs play an importa...
Uncontrolled median openings contribute to more road crashes because drivers do not obey traffic laws such as driving between lanes and following speed limits. This study examined the effectiveness of the different types of signs near an uncontrolled...
The selective retention of fish is a consequence of size and species-dependent fish behaviour during the trawling process. The observation of fish reactions to trawl gear is critical to understanding the behavioural mechanisms responsible for trawl s...
13 June 2022
The aim of this systematic review was to identify the main factors affecting the training process of para-athletes, as well as the barriers they encounter. For this purpose, a systematic review was carried out in accordance with the PRISMA declaratio...
Frequent use of herbicides may impose a risk on non-target species. The objective was to test the combined toxic effect of binary herbicide mixtures—metribuzin:halosulfuron and metribuzin:flumioxazin—on non-target earthworms in two test s...
Hematopoietic cells play a crucial role in the adult retina in health and disease. Monocytes, macrophages, microglia and myeloid angiogenic cells (MACs) have all been implicated in retinal pathology. However, the role that hematopoietic cells play in...
The Ucayali River is one of the most dynamic large rivers in the world, with high rates of channel migration regularly producing cutoffs. In the lower portion of the Ucayali River, before its confluence to the Marañon River where the Amazon Ri...
This study reveals mineral and deformation processes associated with faulting of lacustrine unconsolidated sediments in the Guadix-Baza Basin (Betic Cordillera, S Spain) affected by the Baza Fault. Brittle carbonate and silt sediments develop deforma...
The fitness of the endangered green sea turtle (Chelonia mydas) may be strongly affected by its gut microbiome, as microbes play important roles in host nutrition and health. This study aimed at establishing environmental microbial baselines that can...
Hypertension is the leading cause of cardiovascular affection and premature death worldwide. The spontaneously hypertensive rat (SHR) is the most common animal model of hypertension, which is characterized by secondary ventricular dilation and hydroc...
Peru is an important center of diversity for maize; its different cultivars have been adapted to distinct altitudes and water availability and possess an array of kernel colors (red, blue, and purple), which are highly appreciated by local population...
(1) The aims of this study were to find out the perception of the coaches of male and female football players in the initiation stage of Spanish professional clubs about different factors of the training process (context, talent development, and meth...
An improved method that allows the robust characterization of surfaces is necessary to accurately predict the biofouling formation on construction materials of photobioreactors (PBR). Exopolymeric substances (EPS), such as proteins and polysaccharide...
Background: Transcriptomic and lipidomic dual analyses usually initiate with independent extractive procedures. That entails a difficulty in aligning results from both omics platforms, especially in the case of highly heterogeneous tissues, such as t...
In the western part of the Sierra de los Filabres area, there are fine-grained metamorphic rock bands, showing a field aspect simitar to slates, as previously described in the geological literature of the studied region. They are variable in thicknes...
An innovative synthetic route that involves the thermal treatment of selected Ru co−ordination complexes was used to prepare RuO2-based materials with catalytic activity for oxygen reduction (ORR) and oxygen evolution (OER) reactions. Extensive...
One of the main routes of fish exposure to micro- and nanoplastics (MNPLs) is their ingestion. MNPLs can act as reservoirs of organic contaminants that are adsorbed onto their surfaces, or that can leach from their complex formulations, with potentia...
In recent times, the progress of Clinical Pharmacogenetics has been remarkable [...]
Objective: The aim of the present study was to compare the fascicle length, pennation angle, muscle thickness and stiffness of the biceps femoris long head, and eccentric hamstring strength between injured dominant limbs, injured non-dominant limbs,...
7 December 2022
The present study aimed to examine the changes that occurred in vertical jump and isokinetic dynamometer (ISK) performances at the beginning of a preparatory period (PRE) and at the start of the competitive period (POST). Sixteen U-17 elite female vo...
Larvae of the nematode family Anisakidae are capable of causing parasitic infections in humans associated with the consumption of fishery products, leading to intestinal syndromes and allergic reactions. Anisakidae larvae are widely distributed geogr...
Bacterial resistance to antibiotics is on the rise and hinders the fight against bacterial infections, which are expected to cause millions of deaths by 2050. New antibiotics are difficult to find, so alternatives are needed. One could be metal-based...
In recent years, Industry 4.0 (I4.0) has been a recurrent theme in the literature on Lean Six Sigma (LSS), given the synergies that can arise from their combination. However, their joint implementation presents several challenges. In this article, a...
People living with HIV-1 and HTLV-2 concomitantly show slower CD4+ T cell depletion and AIDS progression, more frequency of the natural control of HIV-1, and lower mortality rates. A similar beneficial effect of this infection has been reported on HC...
Rasagiline is a selective and irreversible inhibitor of monoamine oxidase type B with neuroprotective effect, indicated for the management of Parkinson’s disease. The aim of this work was to evaluate the impact of seven CYP1A2 alleles and of 12...
Hydrocephalus is a central nervous system condition characterized by CSF buildup and ventricular hypertrophy. It is divided into two types: communicative and non-communicating hydrocephalus. Congenital hydrocephalus has been linked to several changes...
In the literature, different DC/DC power electronic converters (PECs) have been found to interconnect high-voltage DC and low-voltage DC grids in the electric power distribution networks of aircraft. In this scenario, the dual-active-bridge (DAB) con...
There is a lack of evidence of the health impacts due to long COVID among children and young people (CYP). The objective of this study is to determine the main clinical characteristics of long COVID in CYP and to investigate the academic, social, and...
The foremost wastage of bakery products which mainly disturbs the food supply chain, especially in remote areas, is fungal growth. Good quality bread, especially with good height and volume, is the demand of every customer. Here, we aimed to develop...
Myelin, critical for the correct function of the nervous system, is organized in different patterns that can include long non-myelinated axonal segments. How myelin patterning is regulated remains unexplained. The carbohydrate-binding protein galecti...
The objective of the study was to evaluate the volumetric wear of four composite materials for CAD/CAM (computer-aided design/computer-aided manufacturing) systems. The materials evaluated were: Cerasmart (CER), Shofu Block HC (SBH), Tetric CAD (TEC)...
METHs are drugs that enter wastewater through the feces and urine of users. Conventional wastewater treatment plants are not capable of removing this type of emerging contaminant, but, in recent years, techniques have been developed to abate drugs of...
Listeria monocytogenes is an opportunistic pathogen that is widely distributed in the environment. Here we show the prevalence and transmission of L. monocytogenes in dairy farms in the Cantabria region, on the northern coast of Spain. A total of 424...
Despite golf’s contribution to health, scientific production related to golf and health has been relatively scarce. This work aims to investigate the state of the art on golf and health and to identify existing gaps and the principal and most n...
With increasing environmental awareness, lignin will play a key role in the transition from the traditional materials industry towards sustainability and Industry 4.0, boosting the development of functional eco-friendly composites for future electron...
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