You are currently viewing a new version of our website. To view the old version click .

6,258 Results Found

  • Feature Paper
  • Article
  • Open Access
3 Citations
2,558 Views
19 Pages

The Sustainable Home Health Care Process Based on Multi-Criteria Decision-Support

  • Filipe Alves,
  • Lino A. Costa,
  • Ana Maria A. C. Rocha,
  • Ana I. Pereira and
  • Paulo Leitão

20 December 2022

The increase in life expectancy has led to a growing demand for Home Health Care (HHC) services. However, some problems can arise in the management of these services, leading to high computational complexity and time-consuming to obtain an exact and/...

  • Article
  • Open Access
1,500 Views
12 Pages

Referrals, Symptoms and Treatment of Patients Referred to a Secondary Spine Centre—How Can We Help?

  • Ruud Droeghaag,
  • Daphne Nabben,
  • Anouk Smeets,
  • Wouter van Hemert,
  • Narender van Orshoven,
  • Henk van Santbrink,
  • Jasper Most and
  • Inez Curfs

4 June 2023

Introduction: Spinal disorders are amongst the conditions with the highest burden of disease. To limit the increase of healthcare-related costs in the ageing population, the selection of different types of care for patients with spinal disorders shou...

  • Article
  • Open Access
20 Citations
3,630 Views
17 Pages

The validation of a sensitive and reliable analytical procedure for the determination of pharmaceutical and personal care products (PPCPs) in solid environmental samples is reported in this study. Initially, two types of derivatization were used for...

  • Article
  • Open Access
1 Citations
3,320 Views
12 Pages

Optimized Continuity of Care Report on Nursing Compliance and Review: A Retrospective Study

  • David Luna-Aleixos,
  • Lorena Francisco-Montesó,
  • Marta López-Negre,
  • Débora Blasco-Peris,
  • Irene Llagostera-Reverter,
  • María Jesús Valero-Chillerón,
  • Ana Dolores Cervera-Pitarch,
  • Andreu Gallego-Clemente,
  • César Leal-Costa and
  • Víctor M. González-Chordá

23 August 2024

The Continuity of Care Report (CCR) is a fundamental document for ensuring high-quality healthcare and a smooth transition between different levels of care. The aim of this study was to evaluate the impact of optimizing the CCR to improve its complet...

  • Article
  • Open Access
1 Citations
1,146 Views
9 Pages

17 October 2024

Background: Patients’ compliance to inhalation therapy is usually sub-optimal in young asthmatics. Adolescents poorly compliant to regular anti-asthma treatments and those with tattoos (and the associated attitude) can share some personality tr...

  • Article
  • Open Access
15 Citations
4,600 Views
12 Pages

Interventions such as kangaroo care (KC) and live-performed music therapy (LPMT), are increasingly used to facilitate stress reduction in neonates. This study aims to investigate the effect of combining the two on physiological responses and neurolog...

  • Article
  • Open Access
2 Citations
2,877 Views
16 Pages

Changes in Treatment of Very Elderly Patients Six Weeks after Discharge from Geriatrics Department

  • Mélanie Dipanda,
  • Jérémy Barben,
  • Gilles Nuémi,
  • Lucie Vadot,
  • Valentine Nuss,
  • Jérémie Vovelle,
  • Alain Putot and
  • Patrick Manckoundia

We assessed the prescriptions of patients hospitalized in a geriatric unit and subsequently discharged. This prospective and observational study was conducted over a two-month period in the geriatrics department (acute and rehabilitation units) of a...

  • Review
  • Open Access
26 Citations
6,484 Views
20 Pages

Systemic Barriers to Optimal Cancer Care in Resource-Limited Countries: Jordanian Healthcare as an Example

  • Razan Mansour,
  • Hikmat Abdel-Razeq,
  • Maysa Al-Hussaini,
  • Omar Shamieh,
  • Akram Al-Ibraheem,
  • Amal Al-Omari and
  • Asem H. Mansour

11 March 2024

This narrative review explores the multifaceted barriers hindering access to quality cancer care in Jordan. A literature-based narrative review was undertaken to explore the current identified barriers to cancer care in Jordan. Four databases were se...

  • Systematic Review
  • Open Access
7 Citations
3,386 Views
17 Pages

Optimal Care Pathways for People in Suicidal Crisis Who Interact with First Responders: A Scoping Review

  • Katelyn Kerr,
  • Ed Heffernan,
  • Jacinta Hawgood,
  • Bronwen Edwards and
  • Carla Meurk

Background: First responders play a vital role in attending to people in suicidal crisis and influencing their care. Aims: To examine existing care pathways and models of care that could be used for people in a suicidal crisis who have come to the at...

  • Article
  • Open Access
53 Citations
4,725 Views
33 Pages

10 November 2021

The ageing population in most parts of the world becomes a grand challenge for healthcare decision-makers. The care of elderly persons and general hygienic care at patients’ homes are two main reasons to motivate an optimization problem, namely, home...

  • Commentary
  • Open Access
7 Citations
2,815 Views
9 Pages

2 November 2023

Patients with incurable cancers have an increasing number of comorbidities, which can lead to polypharmacy and its associated adverse events (drug-to-drug interaction, prescription of a potentially inappropriate medication, adverse drug event). Depre...

  • Review
  • Open Access
6 Citations
5,668 Views
17 Pages

Venetoclax Initiation in Chronic Lymphocytic Leukemia: International Insights and Innovative Approaches for Optimal Patient Care

  • Mary Ann Anderson,
  • Renata Walewska,
  • Fidelma Hackett,
  • Arnon P. Kater,
  • Josie Montegaard,
  • Susan O’Brien,
  • John F. Seymour,
  • Matthew Smith,
  • Stephan Stilgenbauer and
  • Ashley Whitechurch
  • + 1 author

28 February 2024

Venetoclax, a highly selective, oral B-cell lymphoma 2 inhibitor, provides a robust targeted-therapy option for the treatment of chronic lymphocytic leukemia (CLL), including patients with high-risk del(17p)/mutated-TP53 and immunoglobulin heavy vari...

  • Feature Paper
  • Review
  • Open Access
35 Citations
11,951 Views
18 Pages

30 January 2018

This review discusses risks, benefits, and alternatives in patients already taking benzodiazepines when care transfers to a new clinician. Prescribers have the decision—sometimes mutually agreed-upon and sometimes unilateral—to continue, discontinue,...

  • Article
  • Open Access
8 Citations
3,225 Views
20 Pages

Public–private partnership is a type of cooperation that has been widely employed to alleviate contradictions between supply and demand in the elderly care industry in China. Based on evolutionary game theory, this paper mainly analyzes the eff...

  • Protocol
  • Open Access
13 Citations
3,871 Views
9 Pages

KidneyCare Guided Immuno-Optimization in Renal Allografts: The KIRA Protocol

  • Jennifer N. Gray,
  • Theresa Wolf-Doty,
  • Nimisha Sulejmani,
  • Osama Gaber,
  • David Axelrod,
  • Basmah Abdalla and
  • Gabriel Danovitch

30 September 2020

Immunosuppressant agents are essential in every transplant recipient’s care yet walking the fine line of over- or under-immunosuppression is a constant struggle for both patients and transplant providers alike. Optimization and personalization...

  • Review
  • Open Access
5 Citations
3,673 Views
20 Pages

Integrating Primary Care and Specialized Therapies in Rheumatoid Arthritis: Optimizing Recognition, Management, and Referral Practices

  • Dimitrina Miteva,
  • Konstantina Bakopoulou,
  • Ivan Padjen,
  • Issa El Kaouri,
  • Latchezar Tomov,
  • Georgi V. Vasilev,
  • Russka Shumnalieva and
  • Tsvetelina Velikova

Rheumatoid arthritis (RA) is an immune-mediated chronic and long-term condition that can lead to severe joint damage and disability. It has been shown that doctor–patient interaction and communication can have a significant impact on faster pat...

  • Review
  • Open Access
6 Citations
3,132 Views
14 Pages

Can Telemedicine Optimize the HCV Care Cascade in People Who Use Drugs? Features of an Innovative Decentralization Model and Comparison with Other Micro-Elimination Strategies

  • Riccardo Nevola,
  • Valerio Rosato,
  • Vincenza Conturso,
  • Pasquale Perillo,
  • Teresa Le Pera,
  • Ferdinando Del Vecchio,
  • Davide Mastrocinque,
  • Annalisa Pappalardo,
  • Simona Imbriani and
  • Augusto Delle Femine
  • + 2 authors

24 May 2022

People who use drugs (PWUDs) are a crucial population in the global fight against viral hepatitis. The difficulties in linkage to care, the low adherence to therapy, the frequent loss to follow-up and the high risk of re-infection make the eradicatio...

  • Article
  • Open Access
10 Citations
4,838 Views
31 Pages

24 May 2019

Systems that supply medicinal gases—oxygen, nitrous oxide and medical air—serve all care units of a hospital; for example, they feed distribution systems for operating theatres, neonatal and pediatric units, dialysis, X-ray, casualty, spe...

  • Article
  • Open Access
1 Citations
2,483 Views
13 Pages

31 May 2024

The level of NCP implementation varies across countries due to differences identified in major components of health systems such as infrastructures, legislation, training, and cultural diversities. Dietitians in Greece receive sufficient training in...

  • Article
  • Open Access
5 Citations
3,545 Views
17 Pages

Optimizing Patient Information Material for a New Psycho-Oncological Care Program Using a Participatory Health Research Approach in Germany

  • Theresia Krieger,
  • Sandra Salm,
  • Antje Dresen,
  • Anna Arning,
  • Kathrin Schwickerath,
  • Andrea Göttel,
  • Stefanie Houwaart,
  • Holger Pfaff and
  • Natalia Cecon

High-quality patient information material (PIM) is essential for patients´ informed decision-making, and its quality may influence a care program’s acceptance. In the new psycho-oncological care program, isPO, the initial PIM was develope...

  • Communication
  • Open Access
7,610 Views
5 Pages

Electronic health records (EHR) combined with robust data collection systems can be used to simultaneously drive research and performance improvement initiatives. Our Smart, Transformative, EHR-based Approaches to Revolutionizing the Intensive Care U...

  • Article
  • Open Access
4 Citations
7,239 Views
18 Pages

Optimization of a Cell Counting Algorithm for Mobile Point-of-Care Testing Platforms

  • DaeHan Ahn,
  • Nam Sung Kim,
  • SangJun Moon,
  • Taejoon Park and
  • Sang Hyuk Son

19 August 2014

In a point-of-care (POC) setting, it is critically important to reliably count the number of specific cells in a blood sample. Software-based cell counting, which is far faster than manual counting, while much cheaper than hardware-based counting, ha...

  • Article
  • Open Access
2 Citations
1,404 Views
26 Pages

17 April 2025

This paper addresses the critical challenge of optimal allocation and scheduling of Internet of Things (IoT) tracking devices for patient monitoring in healthcare facilities, where limited resources must be efficiently distributed to minimize cost an...

  • Article
  • Open Access
1 Citations
1,817 Views
12 Pages

24 November 2023

Malnutrition is a prevalent geriatric syndrome with adverse health outcomes. This study aimed to assess the effectiveness of an optimized protocol for treatment of malnutrition in older hospitalized patients. We conducted a prospective, non-randomize...

  • Article
  • Open Access
2 Citations
2,623 Views
18 Pages

19 July 2023

In smart elderly care communities, optimizing the design of building energy systems is crucial for improving the quality of life and health of the elderly. This study pioneers an innovative adaptive optimization design methodology for building energy...

  • Article
  • Open Access
1 Citations
2,262 Views
18 Pages

25 January 2025

As society develops, the aging population issue is becoming more serious and gaining global attention. Meanwhile, the building industry worldwide is focusing on making buildings more convenient for the elderly. This study focuses on a health care bui...

  • Article
  • Open Access
5 Citations
2,702 Views
19 Pages

Innovative Orthopedic Solutions for AI-Optimized Piezoelectric Implants for Superior Patient Care

  • Bankole I. Oladapo,
  • Mattew A. Olawumi and
  • Temitope Olumide Olugbade

23 August 2024

This research aims to optimize piezoelectric implants for orthopedic applications, enhancing energy harvesting efficiency and mechanical integrity. Our objectives include comparing piezoelectric materials (PZT, PVDF, and BaTiO3) and employing advance...

  • Article
  • Open Access
9 Citations
3,397 Views
14 Pages

20 January 2023

This paper constructs an evaluation index system for the suitability of community home and institutional elderly care land development, respectively, from different elderly care modes with the data of urban POI, OSM road network, and expert questionn...

  • Article
  • Open Access
620 Views
16 Pages

Optimizing Pediatric Intermediate Care: Clinical Predictors of Deterioration and Length of Stay in a Tertiary Setting

  • Giacomo Brisca,
  • Carlotta Pepino,
  • Marcello Mariani,
  • Giacomo Tardini,
  • Marta Romanengo,
  • Emanuele Giacheri,
  • Marisa Mallamaci,
  • Isabella Buffoni,
  • Valentina Carrato and
  • Marina Francesca Strati
  • + 7 authors

10 September 2025

Background/Objective: Pediatric Intermediate Care Units (PIMCUs) provide enhanced monitoring and support for children who require more care than standard wards but do not meet full Pediatric Intensive Care Unit (PICU) criteria. Despite their growing...

  • Review
  • Open Access
7 Citations
4,148 Views
15 Pages

Optimizing Childhood Obesity Management: The Role of Edmonton Obesity Staging System in Personalized Care Pathways

  • Astrid De Wolf,
  • Elise Nauwynck,
  • Jesse Vanbesien,
  • Willem Staels,
  • Jean De Schepper and
  • Inge Gies

28 February 2024

Childhood obesity, affecting 29% of 7–9-year-olds across 33 European countries, is a significant public health challenge. Its persistence into adulthood poses grave health risks influenced by genetic, environmental, and socio-economic factors....

  • Perspective
  • Open Access
6 Citations
3,451 Views
27 Pages

26 September 2022

Individual differences in the responsiveness of the brain to transcranial electrical stimulation (tES) are increasingly demonstrated by the large variability in the effects of tES. Anatomically detailed computational brain models have been developed...

  • Article
  • Open Access
28 Citations
7,934 Views
15 Pages

(1) Background: Antibiotic resistance is a worldwide health threat. The WHO published a global strategic plan in 2001 to contain antimicrobial resistance. In the following year, a workshop identified crucial barriers to the implementation of the stra...

  • Article
  • Open Access
2 Views
8 Pages

19 September 2012

The European Year of Healthy Ageing recognizes that health care systems need to be improved and reorganized if services are to optimize the opportunities for people to stay healthy and well in their own homes for as long as possible. However, current...

  • Article
  • Open Access
6 Citations
2,793 Views
12 Pages

Optimization of Microfluidics for Point-of-Care Blood Sensing

  • Amirmahdi Tavakolidakhrabadi,
  • Matt Stark,
  • Ulrike Bacher,
  • Myriam Legros and
  • Cedric Bessire

23 May 2024

Blood tests are widely used in modern medicine to diagnose certain illnesses and evaluate the overall health of a patient. To enable testing in resource-limited areas, there has been increasing interest in point-of-care (PoC) testing devices. To proc...

  • Review
  • Open Access
13 Citations
4,761 Views
12 Pages

11 October 2022

Technologies utilizing cutting-edge methodologies, including artificial intelligence (AI), machine learning (ML) and deep learning (DL), present powerful opportunities to help evaluate, predict, and improve patient outcomes by drawing insights from r...

  • Article
  • Open Access
2 Citations
3,366 Views
21 Pages

Optimizing Nurse Rostering: A Case Study Using Integer Programming to Enhance Operational Efficiency and Care Quality

  • Aristeidis Mystakidis,
  • Christos Koukaras,
  • Paraskevas Koukaras,
  • Konstantinos Kaparis,
  • Stavros G. Stavrinides and
  • Christos Tjortjis

17 December 2024

Background/Objectives: This study addresses the complex challenge of Nurse Rostering (NR) in oncology departments, a critical component of healthcare management affecting operational efficiency and patient care quality. Given the intricate dynamics o...

  • Article
  • Open Access
2,304 Views
12 Pages

Optimizing Interhospital Transfers in Orthopedics and Trauma Surgery: Challenges, Insights, and Proposals for Standardized Care in Germany

  • Jonas Roos,
  • Soufian Ben Amar,
  • Leonie Weinhold,
  • Alberto Alfieri Zellner,
  • Amadeo Touet,
  • Christian Prangenberg,
  • Thomas Loy and
  • Martin Gathen

Background: Germany’s high density of under-equipped hospitals and anticipated surge in orthopedic and trauma surgery-related diseases by 2030, combined with personnel shortages, are expected to increase patient transfers between hospitals, an...

  • Article
  • Open Access
4 Citations
3,329 Views
26 Pages

Optimization of Film-Dressings Containing Herbal Extracts for Wound Care—A Quality by Design Approach

  • Diana Antonia Safta,
  • Cătălina Bogdan,
  • Sonia Iurian and
  • Mirela-Liliana Moldovan

25 April 2025

Despite the potential of film dressings for wound healing, many formulations lack an optimized design in order to ensure that the ingredients were carefully chosen to increase the product’s efficacy and stability, while also ensuring the patien...

  • Article
  • Open Access
13 Citations
4,763 Views
15 Pages

Background: Pharmacists are increasingly involved in strategies to fight antimicrobial resistance by ensuring optimised antibiotic (AB) use, including adherence support. Successful adherence interventions should be tailored to patients’ barriers and...

  • Review
  • Open Access
3 Citations
5,457 Views
21 Pages

Optimizing Care Delivery in Patients with Chronic Kidney Disease in the United States: Proceedings of a Multidisciplinary Roundtable Discussion and Literature Review

  • Jamie S. Hirsch,
  • Samuel Colby Danna,
  • Nihar Desai,
  • Ty J. Gluckman,
  • Manisha Jhamb,
  • Kim Newlin,
  • Bob Pellechio,
  • Ahlam Elbedewe and
  • Evan Norfolk

20 February 2024

Background: Approximately 37 million individuals in the United States (US) have chronic kidney disease (CKD). Patients with CKD have a substantial morbidity and mortality, which contributes to a huge economic burden to the healthcare system. A limite...

  • Systematic Review
  • Open Access
9 Citations
4,107 Views
22 Pages

Neoadjuvant Gastric Cancer Treatment and Associated Nutritional Critical Domains for the Optimization of Care Pathways: A Systematic Review

  • Marta Correia,
  • Ines Moreira,
  • Sonia Cabral,
  • Carolina Castro,
  • Andreia Cruz,
  • Bruno Magalhães,
  • Lúcio Lara Santos and
  • Susana Couto Irving

9 May 2023

(1) Background: Gastric cancer patients are known to be at a high risk of malnutrition, sarcopenia, and cachexia, and the latter impairs the patient’s nutritional status during their clinical course and also treatment response. A clearer identi...

  • Review
  • Open Access
8 Citations
4,187 Views
17 Pages

7 April 2024

Radiation therapy (RT) plays a crucial role in the treatment of head and neck cancers (HNCs). This paper emphasizes the importance of effective communication and collaboration between radiation oncologists and dental specialists in the HNC care pathw...

  • Article
  • Open Access
25 Citations
9,282 Views
13 Pages

6 January 2020

Salivary pepsin is a promising marker for the non-invasive diagnosis of laryngopharyngeal reflux (LPR). For reliable results regarding pepsin in saliva, it is critical to standardize the collection, storage, and pre-processing methods. In this study,...

  • Article
  • Open Access
264 Views
13 Pages

21 November 2025

Objective: To characterize debilitating fatigue in children and adults across inactive auto-inflammatory diseases (AID), identifying distinct disease-specific fatigue phenotypes and modifiable risk factors is necessary for optimal care. Methods: A si...

  • Review
  • Open Access
4 Citations
2,480 Views
12 Pages

From Symptoms to Satisfaction: Optimizing Patient-Centered Care in Dry Eye Disease

  • Edoardo Villani,
  • Stefano Barabino,
  • Giuseppe Giannaccare,
  • Antonio Di Zazzo,
  • Pasquale Aragona and
  • Maurizio Rolando

1 January 2025

Dry eye disease (DED) is a multifactorial, chronic, and often relapsing condition with a significant impact on patient quality of life (QoL). Symptoms such as ocular discomfort and visual disturbances are diverse and frequently misaligned with object...

  • Systematic Review
  • Open Access
13 Citations
3,365 Views
13 Pages

Optimizing Patient Care: A Systematic Review of Multidisciplinary Approaches for SLE Management

  • Giorgio Galoppini,
  • Antonio Marangoni,
  • Francesca Cirilli,
  • Francesca Ruffilli,
  • Carlo Garaffoni,
  • Marcello Govoni,
  • Carlo Alberto Scirè,
  • Ettore Silvagni and
  • Alessandra Bortoluzzi

15 June 2023

Systemic lupus erythematosus (SLE) is characterized by multisystemic clinical manifestations ranging from a relatively mild involvement to potentially life-threatening complications. Due to this complexity, a multidisciplinary (MD) approach is the be...

  • Review
  • Open Access
4 Citations
21,571 Views
22 Pages

11 February 2025

Integrating artificial intelligence (AI) into pharmacy operations and drug discovery represents a groundbreaking milestone in healthcare, offering unparalleled opportunities to revolutionize medication management, accelerate drug development, and del...

  • Article
  • Open Access
1 Citations
1,918 Views
22 Pages

Sustainable Primary Cell Banking for Topical Compound Cytotoxicity Assays: Protocol Validation on Novel Biocides and Antifungals for Optimized Burn Wound Care

  • Zhifeng Liao,
  • Nicolas Laurent,
  • Nathalie Hirt-Burri,
  • Corinne Scaletta,
  • Philippe Abdel-Sayed,
  • Wassim Raffoul,
  • Shengkang Luo,
  • Damian J. Krysan,
  • Alexis Laurent and
  • Lee Ann Applegate

6 August 2024

Thorough biological safety testing of topical therapeutic compounds and antimicrobials is a critical prerequisite for appropriate cutaneous wound care. Increasing pathogen resistance rates to traditional antibiotics and antifungals are driving the de...

  • Article
  • Open Access
13 Citations
9,681 Views
11 Pages

1 September 2014

This study presents an optical inspection system for detecting a commercial point-of-care testing product and a new detection model covering from qualitative to quantitative analysis. Human chorionic gonadotropin (hCG) strips (cut-off value of the hC...

  • Review
  • Open Access
45 Citations
8,518 Views
29 Pages

22 June 2020

There have been significant advancements in the safe delivery of anesthesia as well as improvements in surgical technique; however, the perioperative period can still be high risk for the pediatric patient. Perioperative respiratory complications (PR...

of 126