Table of Contents
Mar. Drugs, Volume 17, Issue 4 (April 2019)
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Cover Story (view full-size image) Collagen plays an integral role in cartilage, and with the surge in the development of biomaterials [...] Read more. Collagen plays an integral role in cartilage, and with the surge in the development of biomaterials for cartilage replacement, it is necessary that there is a reliable source of well-characterised collagens that mimic human collagen. The composition and biochemical properties of collagen in teleost cartilage have never been studied. In this founding study, we found that nasal cartilage of hoki contained, the major collagen, type II, and minor collagens, type IX and type XI, with biochemical homology to mammalian collagens. In addition, we detected a 90 kDa, highly glycosylated collagen that has never been identified in any other species. This significant by-product resource holds promise not only, as a source of ingredients for valuable biomaterials, but also for gaining a greater understanding of teleost cartilage. View this paper.