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Marine Drugs publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Sustainable Valorization of Seafood By-Products through Recovery of Valuable Bioactive Compounds 2nd Edition

edited by

Oscar Martinez-Alvarez

and

Ali Bougatef

submission deadline 30 Apr 2026 | 5 articles | Viewed by 20556 | Submission Open

Keywords: seafood upgrading; bioactive molecules; nutraceuticals; cosmeceuticals; high-throughput screenings; protein hydrolysates; marine ingredients; functional food

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Bioactive Compounds for Skin Health

edited by

Hyun Soo Kim

submission deadline 30 Apr 2026 | 3 articles | Viewed by 9007 | Submission Open

Keywords: marine bioactive compounds; marine metabolites; skin health; skin inflammation; marine pharmaceuticals

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Pharmacological Potential of Marine Natural Products, 3rd Edition

edited by

Chang-Lun Shao

submission deadline 30 Apr 2026 | 4 articles | Viewed by 7079 | Submission Open

Keywords: marine natural products; marine drugs; biological activity; structure– activity relationship; antitumor activity; antiviral activity; antibacterial activity; structural determination; mechanism of action

(This special issue belongs to the Section Marine Pharmacology)

Research on Marine Antimicrobial Peptides

edited by

Na Yang

and

Xiao Wang

submission deadline 30 Apr 2026 | 2 articles | Viewed by 5450 | Submission Open

Keywords: marine antimicrobial peptides; structural diversity; host defense mechanisms; multidrug-resistant pathogens; mining and exploration; biosynthesis; anti-infective mechanism; immunoregulation; nanoparticle-based delivery systems; AI-based prediction technologies

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Marine Antiparasitic Agents, 2nd Edition

edited by

Carla Fernandes

, Anabela Cordeiro-da-Silva and Diana Resende

submission deadline 30 Apr 2026 | 2 articles | Viewed by 5408 | Submission Open

Keywords: antiparasitic; marine agents; safe extraction; green chemistry; parasites; helminths; protozoans

(This special issue belongs to the Section Marine Pharmacology)

Innovative Biotechnology Processes for Marine By-Products: From Waste Stream to Value Stream

edited by

Bergé Jean-Pascal

submission deadline 30 Apr 2026 | 2 articles | Viewed by 5308 | Submission Open

Keywords: circular bioeconomy; blue biotechnology; discard-derived molecules; marine bioactive valorization; zero-waste processing; fishery biorefinery; enzymatic bioconversion; marine ingredient LCA

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Bioactive Substances: From By-Products to Innovative Applications

edited by

Wenzheng Shi

and Dandan Ren

submission deadline 30 Apr 2026 | 3 articles | Viewed by 4972 | Submission Open

Keywords: bioactive compounds; biological activity; peptide; protein hydrolysates; extract methods; molecular structures; functional characteristics; by-product utilization; bioaccessibility and bioavailability

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Pharmacognostic Potential of Seaweed Extracts and Metabolites

edited by Rafael Alexandre Faria da Costa Félix

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3538 | Submission Open

Keywords: pharmacognosy; marine natural products; bioactive compounds; human health; veterinary; agriculture; emerging diseases; antimicrobial resistance; extraction

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Compounds as Inhibitors

edited by Seungrak Lee

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3173 | Submission Open

Keywords: marine natural products; bioactive compounds; enzyme inhibition; anticancer agents; antimicrobial agents; immunomodulators; structure– activity relationship; inhibitors

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Defying the Odds: Innate Immunity in Invertebrates Living in Deep-Sea Extreme Environments

edited by

Raul Bettencourt

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1544 | Submission Open

Keywords: deep-sea ecosystems; marine extreme environments; deep-sea invertebrates; invertebrate innate immunity; evolutionary immunology; secondary metabolites from deep sea invertebrates

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Synthesis, Optimization and Biological Activity of Marine Natural Product

edited by Shengrong Liao and

Zejun Xu

submission deadline 30 Apr 2026 | 1 articles | Viewed by 943 | Submission Open

Keywords: marine natural product; synthesis; optimization; biological evaluation; anticancer; antimicrobial activity; design and synthesis

(This special issue belongs to the Section Synthesis and Medicinal Chemistry of Marine Natural Products)

Marine Microbial Metabolites: Isolation, Bioactivity, and Therapeutic Potential

edited by

Hou-Jin Li

submission deadline 30 Apr 2026 | Viewed by 556 | Submission Open

Keywords: marine natural products; marine microorganism; metabolites; isolation; structure elucidation; bioactive; therapeutic potential

Effects of Marine Natural Products in Brain Health and Metabolic Diseases, 2nd Edition

edited by

Vanni Caruso

submission deadline 30 Apr 2026 | 1 articles | Viewed by 439 | Submission Open

Keywords: neuroprotection; mood disorders; sleep; pain; addiction; inflammation; antioxidants; metabolic syndrome; polycystic ovary syndrome (PCOS); weight loss

(This special issue belongs to the Section Marine Pharmacology)

Marine Natural Products Against Inflammatory-Based Diseases

edited by

Cinzia Parolini

and

Elda Favari

submission deadline 30 Apr 2026 | Viewed by 400 | Submission Open

Keywords: N-3 PUFA; marine-derived ingredients; nutraceutical; triglycerides; cardiovascular diseases; obesity; metabolic syndrome; neurodegenerative disease; rheumatoid arthritis; inflammatory bowel diseases; cancer

(This special issue belongs to the Section Marine Pharmacology)

Marine Natural Products for Innovative Dermocosmetic Applications

edited by

Laurent Picot

and Nicolas Bridiau

submission deadline 30 Apr 2026 | Viewed by 216 | Submission Open

Keywords: marine natural products; dermocosmetics; photoprotection; acne management; cancer therapy support; skin microbiome; wound healing; anti-senescence; blue biotechnology; sustainable formulation

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Value-Added Products from Marine Fishes, 2nd Edition

edited by Helena Maria Lourenço,

Sónia Pedro

and

Ana Gomes-Bispo

submission deadline 30 Apr 2026 | Viewed by 211 | Submission Open

Keywords: marine fishes; bioactivity; health benefits; blue economy; chronic diseases

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Bioactive Substances from Jellyfish

edited by

Huahua Yu

submission deadline 30 Apr 2026 | Viewed by 197 | Submission Open

Keywords: jellyfish; bioactive substances; isolation and purification; peptides; toxin; polysaccharides; bioactivity evaluation; mechanism

Computational and Experimental Advances in Bioactive Molecules from Marine Microorganisms

edited by

João Carneiro

and Mariana Alves Reis

submission deadline 30 Apr 2026 | Viewed by 192 | Submission Open

Keywords: marine bioactive metabolites; computational biology; multi-omics integration; machine learning; drug discovery

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Advances in the Application of Analytical Techniques for Marine Drugs Discovery

edited by

Ronald Quinn

submission deadline 1 May 2026 | Viewed by 191 | Submission Open

Keywords: drug development; hit identification; lead optimisation; targets; biological effects

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

Marine Anti-Inflammatory and Antioxidant Agents, 5th Edition

edited by

Donatella Degl'Innocenti

and

Marzia Vasarri

submission deadline 15 May 2026 | 3 articles | Viewed by 6947 | Submission Open

Keywords: marine organisms; inflammation; cytokines; antioxidant agents; anti-inflammatory gents; oxidative stress; ROS/RNS; NF-κ B; mitochondrial oxidative; drug delivery

(This special issue belongs to the Section Marine Pharmacology)

Marine-Derived Polysaccharide-Degrading Enzyme

edited by

Feng Han

submission deadline 15 May 2026 | 1 articles | Viewed by 650 | Submission Open

Keywords: marine-derived polysaccharide-degrading enzyme; marine polysaccharide; marine oligosaccharide; marine microorganism; genome mining; structure– function relationship; industrial application

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Cultivation and Chemical Profiling of Marine Microorganisms

edited by

Zeinab Khalil

submission deadline 15 May 2026 | Viewed by 205 | Submission Open

Keywords: marine microorganisms; cultivation techniques; metabolomics; biosynthetic gene clusters; natural product discovery; marine fungi and actinobacteria; LC– MS/MS and NMR profiling; genome mining; co-culture and elicitation; antibiotic and bioactive compounds

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Nutritional Content, Biologically Active Compounds, and Correlated Health Impacts of Seaweed as a Resource for Nutraceutical, Cosmetic, and Pharmaceutical Applications

edited by Carlos Cardoso and Cláudia Afonso

submission deadline 31 May 2026 | 7 articles | Viewed by 19127 | Submission Open

Keywords: seaweed; biologically active compounds; extraction techniques; health impacts; nutraceuticals; cosmeceuticals; pharmaceutical applications; functional food study

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Synthetic Biology in Marine Microalgae

edited by Yi Xin

submission deadline 31 May 2026 | 4 articles | Viewed by 11095 | Submission Open

Keywords: marine microalgae; high-value compounds; biomass; photosynthesis; synthetic biology; function modules; genetic engineering; metabolic engineering; conditional expression; stress response

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Bioactive Compounds from Challenging Marine Environments

edited by Seulah Lee

submission deadline 31 May 2026 | 3 articles | Viewed by 7946 | Submission Open

Keywords: natural products; extreme marine ecosystems; novel bioactive compounds; marine chemical diversity; structural elucidation

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

Marine Bioactive Peptides: Structure, Function, and Therapeutic Potential, 5th Edition

edited by

Tatiana V. Ovchinnikova

submission deadline 31 May 2026 | 6 articles | Viewed by 7238 | Submission Open

Keywords: marine peptides; structure; function; chemical synthesis; biotechnological production; peptidomics; therapeutic potential; antibacterial; antifungal; antiviral; cytotoxic; neurotoxic; anticancer; anticoagulant; endotoxin-binding; host defense; innate immunity; toxins; peptide drugs

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Green Extraction of High-Value Compounds in Marine Algae

edited by

Padrón-Sanz Carolina

and

Graciliana Lopes

submission deadline 31 May 2026 | 4 articles | Viewed by 6693 | Submission Open

Keywords: green extraction methods; green solvents; biorefinery; ultrasonic assisted extraction; microwave assisted extraction; supercritical fluid extraction; subcritical water extraction; pressurized liquid extraction; pulsed electric field; ionic liquids

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Advances in Secondary Metabolites from Mangrove Holobiont

edited by

Xuefeng Zhou

and

Huaming Tao

submission deadline 31 May 2026 | 5 articles | Viewed by 6593 | Submission Open

Keywords: mangrove holobiont; natural products; pharmacological activities; biosynthetic mechanisms; symbionts communicate; lead compound

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

New Methods in Extraction and Isolation of Marine Natural Products

edited by Débora Tomazi Pereira and

Paz García-García

submission deadline 31 May 2026 | 3 articles | Viewed by 6292 | Submission Open

Keywords: green extraction and isolation of marine natural products; marine extraction methods; isolation techniques; marine natural products; bioactive marine compounds; marine chemistry

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Glycobiology

edited by

Yuki Fujii

Marco Gerdol

, Ogawa Yukiko and

Yasuhiro Ozeki

submission deadline 31 May 2026 | 4 articles | Viewed by 4955 | Submission Open

Keywords: glycan-drug discovery; lectins; structural glycobiology; transcriptome; glycoconjugates; glycosaminoglycans; deep-sea; glycan-relating enzymes; glycomicrobiology

Bioactive Compounds from Marine Invertebrates

edited by

Aiti Vizzini

submission deadline 31 May 2026 | 2 articles | Viewed by 2256 | Submission Open

Keywords: metabolite; peptide; marine invertebrate; marine natural products; biotechnological application; drugs; metabolomic; proteomic; bioinformat

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Marine Algae as Functional Foods

edited by Tânia Sofia Tavares

submission deadline 31 May 2026 | 1 articles | Viewed by 2055 | Submission Open

Keywords: seaweed; bioactivity; extraction; sustainability; industry; food

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Antioxidants 2026

edited by

Immacolata Castellano

submission deadline 31 May 2026 | 2 articles | Viewed by 1999 | Submission Open

Keywords: marine compounds; antioxidants; biosynthesis; marine-inspired products; oxidative stress

Advances in Natural Products of Marine Thraustochytrids

edited by

Carolina Shene

submission deadline 31 May 2026 | 1 articles | Viewed by 1964 | Submission Open

Keywords: marine natural products; bioactive natural products; thraustochytrid metabolism; cultivation conditions; fatty acids; carotenoids; neutral and polar lipids; marine proteins; sulfated polysaccharides

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Microorganisms Bioprospecting, 2nd Edition

edited by

Junfeng Wang

and Qingbo Zhang

submission deadline 31 May 2026 | 2 articles | Viewed by 1416 | Submission Open

Keywords: marine microorganisms; marine natural products; bioactivity screening; structure-activity relationship; genome mining; natural product biosynthesis; biocatalysis; metabolic engineering; synthetic biology; pharmacological mechanisms

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Genome Mining and Discovery of Marine Bioactive Secondary Metabolites

edited by

Jianying Han

submission deadline 31 May 2026 | 1 articles | Viewed by 1084 | Submission Open

Keywords: genome mining; marine natural products; structure elucidation; host– microbe interaction; Biosynthetic Gene Clusters (BGCs); bioactive compounds; marine fungi; marine actinobacteria

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Lectins: Structures, Functions and Applications

edited by

Kanji Hori

submission deadline 31 May 2026 | Viewed by 448 | Submission Open

Keywords: marine organism; lectin; structure; function; molecular evolution; application; biomarker; biosensor; diagnosis; drug; cosmeceutical; nutraceutical

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine-Derived Functional Foods and Nutraceuticals: Novel Compounds, Mechanisms, and Therapeutic Potential

edited by Jun Yang and

Xianxiang Chen

submission deadline 31 May 2026 | Viewed by 333 | Submission Open

Keywords: marine active compounds; functional foods; nutritional interventions; molecular mechanisms; targeted delivery

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Chemical Defense in Marine Organisms, 4th Edition

edited by

Chiara Lauritano

and

Eleonora Montuori

submission deadline 31 May 2026 | Viewed by 203 | Submission Open

Keywords: defense strategies; stress responses; toxins; secondary metabolites; marine organisms; enzymatic pathway activation; bioactive compounds; biotechnological applications

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Bioactive Polyketides from Marine Resources

edited by

Yan-Bo Zeng

submission deadline 31 May 2026 | Viewed by 151 | Submission Open

Keywords: marine animals; marine fungi; marine microorganisms; polyketides; marine natural products; bioactive compounds; chemical structures; biosynthetic pathway; pharmacological mechanism; marine drugs

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Research on Marine-Derived Functional Foods

edited by

Konstantina Nasopoulou

submission deadline 1 Jun 2026 | 1 articles | Viewed by 710 | Submission Open

Keywords: marine organisms; omega-3 fatty acids; peptides; antioxidants; anti-inflammatory effect; cardioprotective activity; innovative processing methods; bioavailability; safety; stability

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine-Derived Agents in Anticancer Targeting and Therapy

edited by

Paola Barraja

and

Alessandra Montalbano

submission deadline 1 Jun 2026 | Viewed by 306 | Submission Open

Keywords: marine natural products; marine-derived compounds; anticancer therapy; targeted cancer therapy; chemical synthesis; structure– activity relationship (SAR); oncogenic pathways; molecular targets; drug discovery and development

(This special issue belongs to the Section Marine Pharmacology)

Sustainable Approaches for the Biotechnological Development of Marine Microalgae-Derived Products

edited by

Serena Lima

and

Chiara Lauritano

submission deadline 15 Jun 2026 | 2 articles | Viewed by 5688 | Submission Open

Keywords: marine bioactive compounds; microalgae; green solvents; sustainable extraction methods; sustainable formulations

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Biotoxins, 4th Edition

edited by

Jordi Molgó

submission deadline 15 Jun 2026 | 5 articles | Viewed by 5575 | Submission Open

Keywords: marine biotoxins; cellular and molecular targets; signaling pathways; metabolism; toxicity; risk factors; molecular interactions; therapeutic potential; ion channels; Ionotropic receptors; ligand-gated receptors; metabotropic receptors

(This special issue belongs to the Section Marine Toxins)

Marine Bioactive Compounds: Roles in Signaling Pathway Regulation and Potential Applications

edited by

Ji-Hye Ahn

submission deadline 15 Jun 2026 | 1 articles | Viewed by 1261 | Submission Open

Keywords: marine bioactive compounds; natural products; signaling pathway regulation; molecular mechanisms of action; inflammation; oxidative stress; cancer; network pharmacology; translational marine pharmacology

(This special issue belongs to the Section Marine Pharmacology)

Marine Natural Products as Promising Modulators of Ferroptosis

edited by Zhongbin Cheng

submission deadline 15 Jun 2026 | 1 articles | Viewed by 951 | Submission Open

Keywords: marine natural products; ferroptosis modulators; inhibitors; inducer; isolation and structural identification; activity; mechanism

(This special issue belongs to the Section Marine Pharmacology)

The Separation and Purification, Structural Elucidation and Applications of Marine Oligosaccharides

edited by

Benwei Zhu

and

Yuya Kumagai

submission deadline 15 Jun 2026 | Viewed by 201 | Submission Open

Keywords: marine oligosaccharides; separation; purification; isolation; structural characterization; chromatography; mass spectrum; membrane separation; thin-layer chromatography

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Animal Natural Products and Their Biosynthesis

edited by

Feng Li

submission deadline 15 Jun 2026 | Viewed by 149 | Submission Open

Keywords: marine animals; natural products; pharmacological activity; biosynthesis; enzymes

(This special issue belongs to the Section Synthesis and Medicinal Chemistry of Marine Natural Products)

Algal Cultivation for Obtaining High-Value Products, 2nd Edition

edited by

Cecilia Faraloni

and

Eleftherios Touloupakis

submission deadline 30 Jun 2026 | 8 articles | Viewed by 16838 | Submission Open

Keywords: algae; photosynthesis; antioxidant; stress; carotenoids; polyphenols; physiology; high-value product; photobioreactor; biotechnology; fatty acids

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

From Marine Natural Products to Marine Bioproducts

edited by

Robert J. Capon

submission deadline 30 Jun 2026 | 7 articles | Viewed by 9916 | Submission Open

Keywords: marine natural products; marine bioproducts; new methodologies and technologies; marine biorefining and bioprocessing; marine bioproducts

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

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