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Mar. Drugs 2019, 17(4), 202; https://doi.org/10.3390/md17040202

Anti-Obesity and Anti-Diabetic Effects of Ishige okamurae

Department of Marine Life Science, Jeju National University, Jeju 63243, Korea
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Received: 15 March 2019 / Revised: 25 March 2019 / Accepted: 25 March 2019 / Published: 29 March 2019
(This article belongs to the Special Issue Marine Natural Products and Obesity)
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Abstract

Obesity is associated with several health complications and can lead to the development of metabolic syndrome. Some of its deleterious consequences are related to insulin resistance, which adversely affects blood glucose regulation. At present, there is a growing concern regarding healthy food consumption, owing to awareness about obesity. Seaweeds are well-known for their nutritional benefits. The brown alga Ishige okamurae (IO) has been studied as a dietary supplement and exhibits various biological activities in vitro and in vivo. The bioactive compounds isolated from IO extract are known to possess anti-obesity and anti-diabetic properties, elicited via the regulation of lipid metabolism and glucose homeostasis. This review focuses on IO extract and its bioactive compounds that exhibit therapeutic effects through several cellular mechanisms in obesity and diabetes. The information discussed in the present review may provide evidence to develop nutraceuticals from IO. View Full-Text
Keywords: Ishige okamurae; marine alga; obesity; diabetes; nutraceuticals Ishige okamurae; marine alga; obesity; diabetes; nutraceuticals
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Yang, H.-W.; Fernando, K.; Oh, J.-Y.; Li, X.; Jeon, Y.-J.; Ryu, B. Anti-Obesity and Anti-Diabetic Effects of Ishige okamurae. Mar. Drugs 2019, 17, 202.

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