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2,915 Results Found

  • Feature Paper
  • Article
  • Open Access
11 Citations
3,909 Views
10 Pages

23 September 2021

The use of ultrasound is a new method to enhance convection drying. However, there is little information in the literature on the improvement of convective heat transfer caused by ultrasound. Therefore, the heat transport during ultrasound-assisted c...

(This article belongs to the Special Issue 10th Anniversary of Applied Sciences: Invited Papers in Applied Thermal Engineering)
  • Review
  • Open Access
10 Citations
4,073 Views
18 Pages

Role of Ultrasound Elastography and Contrast-Enhanced Ultrasound (CEUS) in Diagnosis and Management of Malignant Thyroid Nodules—An Update

  • Carolina Solomon,
  • Diana-Raluca Petea-Balea,
  • Sorin Marian Dudea,
  • Ioana Bene and ,
  • Cristina Alina Silaghi and
  • Manuela Lavinia Lenghel
  • + 1 author+ 0 author

The aim of this paper is to highlight the combined role of ultrasound elastography and contrast-enhanced ultrasound in terms of diagnosis, staging, and follow-up of the post-treatment response. Contrast-enhanced ultrasound (CEUS) and ultrasound elast...

(This article belongs to the Special Issue Advances in the Diagnosis and Management of Cancer/Tumors)
  • Review
  • Open Access
2 Citations
3,683 Views
24 Pages

Expanding Role of Contrast-Enhanced Ultrasound and Elastography in the Evaluation of Abdominal Pathologies in Children

  • Natae Fekadu Lemessa,
  • Laith R. Sultan,
  • Santiago Martinez-Correa,
  • Laura May Davis and
  • Misun Hwang

Contrast-enhanced ultrasound and elastography are two ultrasound technologies that are becoming increasingly popular in the evaluation of different abdominal pathologies in children. The use of these technologies has expanded the diagnostic scope of...

(This article belongs to the Special Issue Abdominal Ultrasound: A Left Behind Area)
  • Article
  • Open Access
3 Citations
1,236 Views
20 Pages

ASMase Activation in Ultrasound-Stimulated Radiation Enhancement Using MRI-Guided Focused Ultrasound

  • Tera N. Petchiny,
  • Deepa Sharma,
  • Anoja Giles,
  • Kai Xuan Leong and ,
  • Wenyi Yang,
  • Lakshmanan Sannachi,
  • David Alberico and
  • Gregory J. Czarnota
  • + 3 authors+ 0 author

17 October 2025

Focused ultrasound-stimulated microbubble (MB + FUS) therapy is a promising radiation enhancement strategy, utilizing vascular disruption to enhance radiation efficacy. However, its mechanistic effects in large tumour volumes and clinical translatabi...

  • Review
  • Open Access
12 Citations
7,551 Views
21 Pages

Deep Learning for Point-of-Care Ultrasound Image Quality Enhancement: A Review

  • Hilde G. A. van der Pol,
  • Lennard M. van Karnenbeek,
  • Mark Wijkhuizen,
  • Freija Geldof and
  • Behdad Dashtbozorg

14 August 2024

The popularity of handheld devices for point-of-care ultrasound (POCUS) has increased in recent years due to their portability and cost-effectiveness. However, POCUS has the drawback of lower imaging quality compared to conventional ultrasound becaus...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Review
  • Open Access
3 Citations
2,577 Views
52 Pages

Assessing Venous Congestion in Heart Failure: A Review of Splanchnic, Cardiac, and Pulmonary Ultrasound: Part 2: Contrast-Enhanced Ultrasound and Shear Wave

  • Francesco Giangregorio,
  • Esther Centenara,
  • Samanta Mazzocchi,
  • Luigi Gerra and ,
  • Francesco Tursi,
  • Davide Imberti and
  • Daniela Aschieri
  • + 2 authors+ 0 author

30 January 2026

Background: Heart failure (HF) is a systemic syndrome characterized by venous congestion, which critically involves the splanchnic circulation. Conventional assessment methods often lack sensitivity for early or regional congestion. Methods: We condu...

(This article belongs to the Section Nuclear Medicine & Radiology)
  • Article
  • Open Access
12 Citations
3,526 Views
11 Pages

Clinical Utility of the Contrast-Enhanced Endoscopic Ultrasound Guided Fine Needle Aspiration in the Diagnosis of Pancreatic Cyst

  • Miruna Patricia Olar,
  • Sorana D. Bolboacă,
  • Cristina Pojoga,
  • Ofelia Moșteanu and ,
  • Marcel Gheorghiu,
  • Radu Seicean,
  • Ioana Rusu,
  • Zeno Sparchez,
  • Nadim Al Hajjar and
  • Andrada Seicean
  • + 5 authors+ 0 author

12 September 2022

Endoscopic ultrasound fine needle aspiration (EUS-FNA) cytology from an intracystic fluid is useful in the differentiation of pancreatic cysts, with low sensitivity, which increases when the solid component is targeted. The clinical utility of contra...

(This article belongs to the Special Issue Advances in Endoscopic Ultrasound)
  • Review
  • Open Access
13 Citations
3,534 Views
10 Pages

The Role of Contrast-Enhanced Harmonic Endoscopic Ultrasound in Interventional Endoscopic Ultrasound

  • Cecilia Binda,
  • Chiara Coluccio,
  • Gianmarco Marocchi,
  • Monica Sbrancia and
  • Carlo Fabbri

11 October 2021

Over the last decades, contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) has emerged as an important diagnostic tool for the diagnosis and differentiation of several gastrointestinal diseases. The key advantage of CH-EUS is that the influx an...

(This article belongs to the Special Issue Recent Advances in Biliopancreatic Endoscopy)
  • Review
  • Open Access
402 Views
22 Pages

Contrast-Enhanced Low-Mechanical-Index Endoscopic Ultrasound for the Evaluation of Focal Liver Lesions

  • Christoph F. Dietrich,
  • Kathleen Möller,
  • Bertrand Napoléon,
  • Michael Hocke and ,
  • Barbara Braden and
  • Christian Jenssen
  • + 1 author+ 0 author

11 August 2026

Contrast-enhanced low-mechanical-index endoscopic ultrasound (CELMI-EUS) extends the diagnostic capabilities of endoscopic ultrasound by enabling real-time assessment of hepatic microvascularization and perfusion using intravenous ultrasound contrast...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
12 Citations
4,322 Views
14 Pages

Contrast-Enhanced Ultrasound Qualitative and Quantitative Characteristics of Parathyroid Gland Lesions

  • Sergejs Pavlovics,
  • Maija Radzina,
  • Rita Niciporuka,
  • Madara Ratniece and ,
  • Madara Mikelsone,
  • Elina Tauvena,
  • Mara Liepa,
  • Peteris Prieditis,
  • Arturs Ozolins and
  • Zenons Narbuts
  • + 6 authors+ 1 author

21 December 2021

Background and Objectives: preoperative differentiation of enlarged parathyroid glands may be challenging in conventional B-mode ultrasound. The aim of our study was to analyse qualitative and quantitative characteristics of parathyroid gland lesions...

  • Article
  • Open Access
25 Citations
4,650 Views
12 Pages

Contrast-Enhanced Ultrasound for Assessing Abdominal Conditions in Pregnancy

  • Thomas Geyer,
  • Johannes Rübenthaler,
  • Matthias F. Froelich,
  • Laura Sabel and ,
  • Constantin Marschner,
  • Vincent Schwarze and
  • Dirk-André Clevert
  • + 2 authors+ 0 author

8 December 2020

Background and objectives: Native ultrasound is the most common imaging modality in obstetrics. The use of contrast-enhanced ultrasound (CEUS) during pregnancy has not been officially approved by leading societies for obstetrics and ultrasound. The p...

(This article belongs to the Special Issue Pregnancy: Diagnosis, Misdiagnosis, Complications and Outcomes)
  • Review
  • Open Access
4 Citations
2,173 Views
23 Pages

How to Perform Cardiac Contrast-Enhanced Ultrasound (cCEUS): Part II—Advanced Applications and Interpretation

  • Harald Becher,
  • Andreas Helfen,
  • Guido Michels,
  • Nicola Gaibazzi and ,
  • Roxy Senior and
  • Christoph Frank Dietrich
  • + 1 author+ 0 author

18 September 2025

Ultrasound enhancing agents (UEAs, formerly called contrast agents) have enhanced echocardiographic diagnostics of myocardial disease and masses as well as myocardial perfusion abnormalities. This review provides up-to-date guidance on the procedures...

(This article belongs to the Special Issue New Perspectives in Cardiac Imaging)
  • Article
  • Open Access
7 Citations
4,091 Views
13 Pages

Multiparametric Ultrasound Approach Using a Tree-Based Decision Classifier for Inconclusive Focal Liver Lesions Evaluated by Contrast Enhanced Ultrasound

  • Tudor Voicu Moga,
  • Ciprian David,
  • Alina Popescu,
  • Raluca Lupusoru and ,
  • Darius Heredea,
  • Ana M. Ghiuchici,
  • Camelia Foncea,
  • Adrian Burdan,
  • Roxana Sirli and
  • Ioan Sporea
  • + 8 authors+ 3 authors

20 December 2021

Background: Multiparametric ultrasound (MPUS) is a concept whereby the examiner is encouraged to use the latest features of an ultrasound machine. The aim of this study was to reanalyze inconclusive focal liver lesions (FLLs) that had been analyzed v...

  • Review
  • Open Access
6 Citations
3,499 Views
24 Pages

How to Perform Cardiac Contrast-Enhanced Ultrasound (cCEUS): Part I

  • Harald Becher,
  • Andreas Helfen,
  • Guido Michels,
  • Nicola Gaibazzi and ,
  • Roxy Senior and
  • Christoph Frank Dietrich
  • + 1 author+ 0 author

Ultrasound enhancing agents (UEAs, formerly called contrast agents) for assessments of the left heart have improved the applicability of echocardiography and the accuracy of echocardiographic measurements. UEAs have been recommended for several diagn...

(This article belongs to the Special Issue New Perspectives in Cardiac Imaging)
  • Article
  • Open Access
3 Citations
1,939 Views
14 Pages

The Diagnostic Value of Multimodal Contrast-Enhanced Ultrasound in Sentinel Lymph Nodes After Neoadjuvant Therapy for Breast Cancer

  • Jiaqian Zhong,
  • Jia Luo,
  • Jiaping Li,
  • Manying Li and ,
  • Yingli Liu,
  • Jinyu Liang,
  • Fushun Pan,
  • Xiaoyan Xie and
  • Yanling Zheng
  • + 4 authors+ 0 author

24 September 2025

Objective: Accurate diagnosis of sentinel lymph node (SLN) status after neoadjuvant therapy (NAT) for breast cancer is crucial for guiding axillary management. This study aimed to evaluate novel contrast-enhanced ultrasound (CEUS) patterns for assess...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
23 Citations
4,942 Views
14 Pages

Concurrent Osteosarcoma Theranostic Strategy Using Contrast-Enhanced Ultrasound and Drug-Loaded Bubbles

  • Tai-Tzung Kuo,
  • Chung-Hsin Wang,
  • Jir-You Wang,
  • Hong-Jen Chiou and ,
  • Ching-Hsiang Fan and
  • Chih-Kuang Yeh
  • + 1 author+ 0 author

Osteosarcoma (OS) is the most common bone tumor in children and teenagers. The multidrug resistant property of OS produces a major obstacle to chemotherapy, since the effective drug dose cannot be achieved via conventional drug delivery routes withou...

(This article belongs to the Special Issue Micro/Nano-Bubbles as a New Ultrasound Imaging and Drug Delivery Tool)
  • Article
  • Open Access
3 Citations
4,109 Views
12 Pages

Utility of Contrast-Enhanced Ultrasound in Optimizing Hepatic Abscess Treatment and Monitoring

  • Adam Dobek,
  • Mateusz Kobierecki,
  • Konrad Kosztowny,
  • Oliwia Grząsiak and ,
  • Adam Fabisiak,
  • Krzysztof Falenta and
  • Ludomir Stefańczyk
  • + 2 authors+ 0 author

26 August 2024

Background/Objectives: Untreated hepatic abscesses (HAs) have an 80% mortality rate and can be caused by bacteria and fungi. Previously managed with surgery, current treatments now utilize interventional radiology and antibiotics, reducing complicati...

(This article belongs to the Topic Hepatobiliary and Pancreatic Diseases: Novel Strategies of Diagnosis and Treatments)
  • Review
  • Open Access
51 Citations
5,384 Views
11 Pages

Contrast-Enhanced Ultrasound for Monitoring Treatment Response in Different Stages of Hepatocellular Carcinoma

  • Mariella Faccia,
  • Matteo Garcovich,
  • Maria Elena Ainora,
  • Laura Riccardi and ,
  • Maurizio Pompili,
  • Antonio Gasbarrini and
  • Maria Assunta Zocco
  • + 2 authors+ 0 author

18 January 2022

The capacity of contrast-enhanced ultrasound (CEUS) to detect microvessel perfusion has received much attention in cancer imaging since it can be used to evaluate the enhancement patterns of the lesions during all vascular phases in real time, with h...

(This article belongs to the Special Issue Curative Strategies for the Management of Hepatocellular Cancer)
  • Article
  • Open Access
29 Citations
4,505 Views
20 Pages

29 August 2022

As an important secondary zinc resource, large-scale reserves of zinc oxide dust (ZOD) from a wide range of sources is of high comprehensive recycling value. Therefore, an experimental study on ultrasound-enhanced sulfuric acid leaching for zinc extr...

(This article belongs to the Special Issue Recovery of Non-ferrous Metal from Metallurgical Residues)
  • Article
  • Open Access
7 Citations
2,860 Views
11 Pages

Background: Subpleural focal organizing pneumonia (FOP) and primary lung malignancy (PLM) are usually confused. The aim of this study was to explore the value of ultrasound (US) and contrast-enhanced ultrasound (CEUS) in the differential diagnosis of...

(This article belongs to the Special Issue Ultrasound Imaging in Medicine 2022)
  • Article
  • Open Access
11 Citations
3,633 Views
14 Pages

Challenges in Diagnosing Focal Liver Lesions Using Contrast-Enhanced Ultrasound

  • Tudor Voicu Moga,
  • Raluca Lupusoru,
  • Mirela Danila,
  • Ana Maria Ghiuchici and ,
  • Alina Popescu,
  • Bogdan Miutescu,
  • Iulia Ratiu,
  • Calin Burciu,
  • Teofana Bizerea-Moga and
  • Roxana Sirli
  • + 7 authors+ 2 authors

Background: Contrast-enhanced ultrasound (CEUS) has become the preferred method for many clinicians in evaluating focal liver lesions (FLLs) initially identified through standard ultrasound. However, in clinical practice, certain lesions may deviate...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
23 Citations
4,325 Views
12 Pages

10 August 2020

Friction stir welding (FSW) is an innovative solid-state joining process, which is suitable for joining dissimilar materials with strongly differing physical and chemical properties such as aluminum and steel. Where other joining methods such as fusi...

(This article belongs to the Special Issue Advanced Process Technologies Based on Friction Stir Welding and Linear Friction Welding)
  • Review
  • Open Access
11 Citations
5,229 Views
15 Pages

28 July 2023

In recent years, advancements in technology have allowed the use of contrast-enhanced ultrasounds (CEUS) with high-frequency transducers, which in turn, led to new possibilities in diagnosing a variety of diseases and conditions in the field of radio...

(This article belongs to the Section Pediatric Neurology & Neurodevelopmental Disorders)
  • Review
  • Open Access
6 Citations
7,586 Views
15 Pages

17 August 2022

Contrast-enhanced ultrasound (CEUS) is an emerging technology in veterinary medicine involving the administration of intravenous contrast agents, and it is increasingly recognized for its high potential as a diagnostic imaging tool for small animals....

(This article belongs to the Special Issue Contrast-Enhanced Ultrasound (CEUS) in Small and Large Animals)
  • Article
  • Open Access
10 Citations
3,324 Views
15 Pages

Application of Dynamic Contrast-Enhanced Ultrasound in Evaluation the Activity of Crohn’s Disease

  • Ying Wang,
  • Li Wei,
  • Wen-Song Ge,
  • You-Rong Duan and ,
  • Wen-Jun Ding,
  • Xiu-Yun Lu,
  • Yun-Lin Huang,
  • Sheng Chen,
  • Yi Dong and
  • Peng Du
  • + 5 authors+ 0 author

Background and Objective: The dynamic assessment of disease activity during the follow-up of patients with Crohn’s disease (CD) remains a significant challenge. In this study, we aimed to identify the role of dynamic contrast-enhanced ultrasoun...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
8 Citations
3,225 Views
9 Pages

Role of Contrast-Enhanced Ultrasound in the Follow-Up after Endovascular Abdominal Aortic Aneurysm Repair

  • Filippo Benedetto,
  • Domenico Spinelli,
  • Francesco La Corte,
  • Narayana Pipitò and ,
  • Gabriele Passari and
  • Giovanni De Caridi
  • + 1 author+ 0 author

15 December 2022

Background: The aim of this study was to assess whether contrast-enhanced ultrasound (CEUS) shows a false negative rate close to zero and therefore is suitable as the main non-invasive follow-up strategy for long-term monitoring after endovascular ao...

(This article belongs to the Collection Vascular Diseases Diagnostics)
  • Article
  • Open Access
15 Citations
4,687 Views
15 Pages

Ultrasound-Enhanced Hot Air Drying of Germinated Highland Barley Seeds: Drying Characteristics, Microstructure, and Bioactive Profile

  • Yan Song,
  • Yang Tao,
  • Xiaoyu Zhu,
  • Yongbin Han and ,
  • Pau Loke Show,
  • Changnain Song and
  • Hayyiratul Fatimah Mohd Zaid
  • + 2 authors+ 0 author

The effects of ultrasound-enhanced hot air drying on the drying characteristics, microstructure and bioactive profile of germinated highland barley seeds (GHB) were studied. GHB was dried by hot air at 55 °C and 70 °C and ultrasonic intensiti...

  • Article
  • Open Access
9 Citations
2,769 Views
10 Pages

Contrast-Enhanced Intraoperative Ultrasound Shows Excellent Performance in Improving Intraoperative Decision-Making

  • Laura S. Kupke,
  • Ivor Dropco,
  • Markus Götz,
  • Paul Kupke and ,
  • Friedrich Jung,
  • Christian Stroszczynski and
  • Ernst-Michael Jung
  • + 2 authors+ 0 author

22 September 2024

Background: The aim of this study was to evaluate the performance and the impact of contrast-enhanced intraoperative ultrasound (CE-IOUS) on intraoperative decision-making, as there is still no standardized protocol for its use. Therefore, we retrosp...

(This article belongs to the Special Issue Microvascular Dynamics: Insights and Applications)
  • Review
  • Open Access
23 Citations
5,491 Views
30 Pages

Enhancing Targeted Therapy in Breast Cancer by Ultrasound-Responsive Nanocarriers

  • Isaiah A. Edwards,
  • Flavia De Carlo,
  • Juliana Sitta,
  • William Varner and ,
  • Candace M. Howard and
  • Pier Paolo Claudio
  • + 1 author+ 0 author

Currently, the response to cancer treatments is highly variable, and severe side effects and toxicity are experienced by patients receiving high doses of chemotherapy, such as those diagnosed with triple-negative breast cancer. The main goal of resea...

(This article belongs to the Special Issue Bioinspired Functional Materials for Biomedical Applications)
  • Article
  • Open Access
9 Citations
5,461 Views
13 Pages

Contrast-Enhanced Ultrasound Imaging of Prostate Gland in Neutered Dogs

  • Stefano Spada,
  • Gary C. W. England,
  • Massimo Vignoli,
  • Augusto Carluccio and
  • Marco Russo

20 February 2021

Prostatic neoplasia (PN) occurs in 5–7% of dogs with prostatic disease, with castrated dogs having the same or higher prevalence when compared to intact dogs. Considering the promising results achieved by performing contrast-enhanced ultrasound (CEUS...

(This article belongs to the Special Issue Veterinary and Comparative Reproductive Pathology)
  • Review
  • Open Access
180 Views
16 Pages

Diagnostic Value of Gastrointestinal Ultrasound (GIUS), Including Doppler and Contrast-Enhanced Ultrasound (CEUS), in the Assessment of Inflammatory Bowel Disease Activity: A Scoping Review

  • Radosław Korczyk,
  • Angelika Złotnik,
  • Paweł Ścierski,
  • Barbara Lipka and ,
  • Piotr Oleś and
  • Aleksandra Kawczyk-Krupka
  • + 1 author+ 0 author

15 October 2026

Background/Objectives: Treat-to-target management of inflammatory bowel disease (IBD) requires frequent, accurate assessment of disease activity. Endoscopy remains the reference standard, but its invasiveness limits repeated use, which has increased...

(This article belongs to the Special Issue Advanced Endoscopy and Imaging in Gastrointestinal Diseases)
  • Article
  • Open Access
2 Citations
2,587 Views
12 Pages

Deep Learning Detection and Segmentation of Facet Joints in Ultrasound Images Based on Convolutional Neural Networks and Enhanced Data Annotation

  • Lingeer Wu,
  • Di Xia,
  • Jin Wang,
  • Si Chen and ,
  • Xulei Cui,
  • Le Shen and
  • Yuguang Huang
  • + 2 authors+ 0 author

The facet joint injection is the most common procedure used to release lower back pain. In this paper, we proposed a deep learning method for detecting and segmenting facet joints in ultrasound images based on convolutional neural networks (CNNs) and...

(This article belongs to the Special Issue Deep Learning Techniques for Medical Image Analysis)
  • Article
  • Open Access
12 Citations
8,138 Views
12 Pages

Imaging Features of Hepatocellular Carcinoma in the Non-Cirrhotic Liver with Sonazoid-Enhanced Contrast-Enhanced Ultrasound

  • Sheng Chen,
  • Yi-Jie Qiu,
  • Dan Zuo,
  • Shuai-Nan Shi and ,
  • Wen-Ping Wang and
  • Yi Dong
  • + 1 author+ 0 author

20 September 2022

Purpose: To investigate the Sonazoid-enhanced contrast-enhanced ultrasound (CEUS) features of hepatocellular carcinoma (HCC) in a non-cirrhosis liver background, in comparison to those in liver cirrhosis. Methods: In this retrospective study, 19 pati...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
9 Citations
2,497 Views
10 Pages

12 February 2021

The aim of this study was to assess the usefulness of contrast-enhanced ultrasound (CEUS) for predicting the therapeutic efficacy of transarterial chemoembolization with drug-eluting beads (DEB-TACE) for hepatocellular carcinoma (HCC). Thirty-two pat...

(This article belongs to the Special Issue Abdominal Ultrasound and Treatment of Hepatocellular Carcinoma)
  • Article
  • Open Access
14 Citations
7,224 Views
21 Pages

A q-Extension of Sigmoid Functions and the Application for Enhancement of Ultrasound Images

  • Paulo Sergio Rodrigues,
  • Guilherme Wachs-Lopes,
  • Ricardo Morello Santos,
  • Eduardo Coltri and
  • Gilson Antonio Giraldi

23 April 2019

This paper proposes the q-sigmoid functions, which are variations of the sigmoid expressions and an analysis of their application to the process of enhancing regions of interest in digital images. These new functions are based on the non-extensive Ts...

(This article belongs to the Special Issue Entropy in Image Analysis)
  • Review
  • Open Access
28 Citations
6,620 Views
12 Pages

Role of Contrast-Enhanced Ultrasound (CEUS) in Native Kidney Pathology: Limits and Fields of Action

  • Antonio Granata,
  • Irene Campo,
  • Paolo Lentini,
  • Francesco Pesce and ,
  • Loreto Gesualdo,
  • Antonio Basile,
  • Vito Cantisani,
  • Matthias Zeiler and
  • Michele Bertolotto
  • + 4 authors+ 0 author

Gray scale ultrasound has an important diagnostic role in native kidney disease. Low cost, absence of ionizing radiation and nephrotoxicity, short performance time, and repeatability even at the bedside, are the major advantages of this technique. Th...

(This article belongs to the Special Issue Imaging in Kidney Disease)
  • Article
  • Open Access
21 Citations
4,493 Views
8 Pages

Diagnostic Performance of Contrast-Enhanced Ultrasound (CEUS) in the Evaluation of Solid Renal Masses

  • Thomas Geyer,
  • Vincent Schwarze,
  • Constantin Marschner,
  • Moritz L. Schnitzer and ,
  • Matthias F. Froelich,
  • Johannes Rübenthaler and
  • Dirk-André Clevert
  • + 2 authors+ 0 author

19 November 2020

Background: The present study aims to evaluate the diagnostic performance of contrast-enhanced ultrasound (CEUS) for discriminating between benign and malignant solid renal masses. Methods: 18 patients with histopathologically confirmed benign solid...

(This article belongs to the Special Issue Imaging of the Kidney and Urinary Tract)
  • Review
  • Open Access
11 Citations
4,401 Views
11 Pages

The Role of Contrast-Enhanced Ultrasound (CEUS) in the Detection of Neoplastic Portal Vein Thrombosis in Patients with Hepatocellular Carcinoma

  • Lucia Cerrito,
  • Maria Elena Ainora,
  • Silvino Di Francesco,
  • Linda Galasso and ,
  • Antonio Gasbarrini and
  • Maria Assunta Zocco
  • + 1 author+ 0 author

20 October 2023

Hepatocellular carcinoma (HCC) is the principal primary liver cancer and one of the most frequent malignant tumors worldwide in patients with chronic liver disease. When diagnosed at an advanced stage, it is often associated with portal vein tumor th...

  • Brief Report
  • Open Access
12 Citations
3,854 Views
9 Pages

Qualitative Assessment of Contrast-Enhanced Ultrasound in Differentiating Clear Cell Renal Cell Carcinoma and Oncocytoma

  • Antonio Tufano,
  • Costantino Leonardo,
  • Chiara Di Bella,
  • Giuseppe Lucarelli and ,
  • Vincenzo Dolcetti,
  • Piervito Dipinto,
  • Flavia Proietti,
  • Rocco Simone Flammia,
  • Umberto Anceschi and
  • Vito Cantisani
  • + 9 authors+ 4 authors

23 April 2023

Background: We aimed to assess whether clear cell renal cell carcinoma (ccRCC) can be differentiated from renal oncocytoma (RO) on a contrast-enhanced ultrasound (CEUS). Methods: Between January 2021 and October 2022, we retrospectively queried and a...

(This article belongs to the Section Nuclear Medicine & Radiology)
  • Article
  • Open Access
19 Citations
3,490 Views
15 Pages

Contrast-Enhanced Ultrasound in Distinguishing between Malignant and Benign Peripheral Pulmonary Consolidations: The Debated Utility of the Contrast Enhancement Arrival Time

  • Carla Maria Irene Quarato,
  • Beatrice Feragalli,
  • Donato Lacedonia,
  • Gaetano Rea and ,
  • Giulia Scioscia,
  • Evaristo Maiello,
  • Concetta Di Micco,
  • Cristina Borelli,
  • Antonio Mirijello and
  • Marco Sperandeo
  • + 8 authors+ 3 authors

10 February 2023

Background. Limited studies and observations conducted on a too small number of patients prevent determining the actual clinical utility of pulmonary contrast-enhanced ultrasound (CEUS). The aim of the present study was to examine the efficacy of con...

(This article belongs to the Special Issue Advances in Chest Imaging Diagnostics)
  • Article
  • Open Access
2 Citations
3,535 Views
10 Pages

Comparison of Linear and Convex-Array Transducers in Assessing the Enhancement Characteristics of Suspicious Breast Lesions at Contrast-Enhanced Ultrasound (CEUS)

  • Ioana Boca (Bene),
  • Anca Ileana Ciurea,
  • Cristiana Augusta Ciortea,
  • Ștefan Cristian Vesa and
  • Sorin Marian Dudea

The purpose of this study was to determine the observer agreement in assessing the enhancement pattern of suspicious breast lesions with contrast-enhanced ultrasound (CEUS) using high and low frequency transducers. Methods: This prospective study inc...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
7 Citations
4,330 Views
13 Pages

Diagnostic Value of Contrast-Enhanced Ultrasound for Evaluation of Transjugular Intrahepatic Portosystemic Shunt Perfusion

  • Constantin A. Marschner,
  • Thomas Geyer,
  • Matthias F. Froelich,
  • Johannes Rübenthaler and ,
  • Vincent Schwarze and
  • Dirk-André Clevert
  • + 1 author+ 0 author

1 September 2021

Background: In patients with liver cirrhosis, transjugular intrahepatic portosystemic shunt (TIPS) displays an effective method for treating portal hypertension. Main indications include refractory ascites and secondary prevention of esophageal bleed...

(This article belongs to the Special Issue Novel Approaches in Oncologic Imaging)
  • Review
  • Open Access
2,905 Views
20 Pages

Necrotizing (Abscessing) Lymphadenopathy and the Diagnostic Value of Contrast-Enhanced Ultrasound (CEUS): A Review with Clinical Vignettes

  • Christian Görg,
  • Yi Dong,
  • Görg Friedemann,
  • Christian Jenssen and ,
  • Michael Kallenbach,
  • Kathleen Möller,
  • Findeisen Hajo,
  • Nitin Chaubal and
  • Christoph Frank Dietrich
  • + 4 authors+ 0 author

Necrotizing (abscessing) lymphadenopathy is a clinically relevant condition with a broad differential diagnosis, including acute bacterial infections, mycobacterial disease, zoonoses, fungal and parasitic infections, autoimmune disorders, and maligna...

(This article belongs to the Special Issue Ultrasound Imaging: Current Status and Future Perspectives)
  • Review
  • Open Access
5 Citations
2,478 Views
12 Pages

Role of B-Mode and Contrast-Enhanced Ultrasound in the Diagnostic Workflow of Gastro-Entero-Pancreatic Neuroendocrine Tumors (GEP-NETs)

  • Linda Galasso,
  • Maria Grazia Maratta,
  • Valeria Sardaro,
  • Giorgio Esposto and ,
  • Irene Mignini,
  • Raffaele Borriello,
  • Antonio Gasbarrini,
  • Maria Elena Ainora,
  • Giovanni Schinzari and
  • Maria Assunta Zocco
  • + 5 authors+ 0 author

4 June 2025

Gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs) represent a rare and varied class of neoplasms, characterized by diverse clinical presentations and prognostic trajectories. Accurate and prompt diagnosis is vital to inform and optimize thera...

(This article belongs to the Special Issue Developments in the Management of Gastrointestinal Malignancies (2nd Edition))
  • Article
  • Open Access
4 Citations
3,450 Views
20 Pages

24 June 2020

The assessment of microvascular perfusion is essential for the diagnosis of a specific muscle disease. In comparison with the current available medical modalities, the contrast-enhanced ultrasound imaging is the simplest and fastest means for probing...

(This article belongs to the Special Issue Advances in Sensors and Sensing for Technical Condition Assessment and NDT)
  • Review
  • Open Access
36 Citations
10,735 Views
11 Pages

27 February 2015

In association with the widespread use of prostate specific antigen (PSA) screening, the numbers of men identified with early-stage prostate cancer (PCa) are increasing in the developed countries, including Japan. However, the accurate localization o...

(This article belongs to the Special Issue Ultrasonic Sensors and Transducers for Applications in Biology, Medicine and NDT)
  • Article
  • Open Access
1,021 Views
12 Pages

A Preliminary Study on Contrast Enhanced Ultrasound Characteristics of Solid Pseudopapillary Neoplasms and Pancreatoblastoma in Children

  • Yuxin Tang,
  • Juan Wang,
  • Lirong Zhu,
  • Jingyu Chen and ,
  • Hongli Zhai and
  • Yi Tang
  • + 1 author+ 0 author

Objective: Solid pseudopapillary neoplasms (SPN) and pancreatoblastoma (PB) have a low overall incidence but represent the most common pancreatic tumors in childhood. Currently, there is a lack of systematic descriptions of contrast-enhanced ultrasou...

(This article belongs to the Special Issue Advances in Gynecological and Pediatric Imaging)
  • Article
  • Open Access
3 Citations
979 Views
16 Pages

Texture Analysis of Histology Images for Characterizing Ultrasound-Stimulated Microbubble Radiation Enhancement Treatment Response

  • Lakshmanan Sannachi,
  • Serena Mohabir,
  • Evan McNabb,
  • Deepa Sharma and ,
  • Anoja Giles,
  • Wenyi Yang,
  • Kai Xuan Leong,
  • Martin Stanisz and
  • Gregory J. Czarnota
  • + 4 authors+ 0 author

18 December 2025

Ultrasound-stimulated microbubble (USMB) therapy, in combination with radiotherapy (XRT), represents a promising approach to enhancing the efficacy of conventional cancer treatments by targeting tumor vasculature. Recent preclinical studies using MRI...

(This article belongs to the Section Cellular Pathology)
  • Article
  • Open Access
508 Views
13 Pages

Perfusion Patterns of Pleura-Based Pulmonary Sarcoma Metastases on Contrast-Enhanced Ultrasound (CEUS): A Single-Center Retrospective Pilot Study

  • Felix Ragnar Merlin Koenig,
  • Christian Görg,
  • Helmut Prosch,
  • Veronika Vetchy and ,
  • Anna Hohensteiner,
  • Nikolai A. Gantner,
  • Daria Kifjak,
  • Florian Lindenlaub,
  • Philipp Theodor Funovics and
  • Ehsan Safai Zadeh
  • + 6 authors+ 1 author

Background/Objectives: Pleura-based pulmonary nodules in soft-tissue sarcoma (STS) patients remain diagnostically challenging, and entity-specific contrast-enhanced ultrasound (CEUS) data are scarce. We aimed to characterize CEUS perfusion patterns o...

(This article belongs to the Special Issue (Bio)sensors for Medical Diagnostics)
  • Review
  • Open Access
515 Views
17 Pages

Dynamic Contrast-Enhanced Ultrasound for Carotid Plaque Characterization: An Algorithm-Aware Technical Review

  • Nicola Morelli,
  • Marco Spallazzi,
  • Marina Biondi,
  • Eugenia Rota and ,
  • Lucia Mazza,
  • Paolo Immovilli and
  • Davide Colombi
  • + 2 authors+ 0 author

Carotid artery disease has traditionally been assessed according to luminal stenosis, although plaques with similar narrowing may differ substantially in biological activity and clinical risk. Intraplaque neovascularization is a key feature of plaque...

(This article belongs to the Special Issue Ultrasound Imaging in Medicine in 2026)

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