In this paper, experimental and numerical studies were conducted to differentiate solvent exsolution and liberation processes from different heavy oil–solvent systems in bulk phases and porous media. Experimentally, two series of constant-compo...
Obtaining an ideal solvent system for target compounds is still an obstacle to the wide application of high-speed counter-current chromatography (HSCCC). The partition coefficient and retention of the stationary phase are two key parameters for solve...
Currently, only a limited number of Mark–Houwink–Sakurada (MHS) equations are available for chitin, and their applicability is constrained by the narrow range of suitable solvent systems. The Mark–Houwink–Sakurada (MHS) equati...
Solid multicomponent systems (SMS) are gaining an increasingly important role in the pharmaceutical industry, to improve the physicochemical properties of active pharmaceutical ingredients (APIs). In recent years, various processes have been employed...
Understanding the interactions between solutes and solvents is vital in many areas of the chemical sciences. Solvation free energy (SFE) is an important thermodynamic property in characterising molecular solvation and so accurate prediction of this p...
This work studies the partition of phenolic compounds, namely caffeic acid, syringic acid, vanillic acid, ferulic acid, and vanillin, in aqueous two-phase systems (ATPSs) formed by acetonitrile and deep eutectic solvents (DESs) based on choline chlor...
This paper shows that low concentrations of either a low-molecular-weight or a recyclable polymeric cosolvent can be used to design recyclable, tunable alkane polymeric solvent systems. We have shown that dyes experience a microheterogeneous environm...
A novel Trichloromethane (TCM)/2,2,2-Trifluoroethanol (TFE) solvent system was developed for fabricating electrospun thermoplastic polyurethane (TPU) nanofibers. TPU solution stability made from this novel solvent system was improved compared to that...
Numerous compounds that are scavengers of hydroxyl radicals (•OH) in Fenton systems have low solubility in water. Therefore, they are dissolved in organic solvents to reach suitable concentrations in the reaction milieu of the Fenton system. How...
We designed a gradient solvent strategy for the reduction of graphene oxide, matching the hydrophilic properties of graphene oxide (GO) and reduced graphene oxide (RGO), respectively. A third solvent was added dropwise to regulate the hydrophilic var...
This paper discloses six polymorphs of famoxadone obtained from polymorph screening, which were characterized by XRPD, DSC, and SEM. A study of solvent-mediated polymorphic transformation (SMPT) of famoxadone from the metastable Form II to the stable...
Wet organic wastes are especially troublesome in valorization. Therefore, innovative solutions are still in demand to make valorization feasible. In this study, we tested a new transformation route of a blackcurrant pomace as a high-moisture industri...
Background/Objectives: Capric acid (CA)–therapeutic deep eutectic systems (THEDES) are emerging as a distinct class of biofunctional matrices capable of reshaping drug solubilization, permeability, and bioactivity. Methods: Relevant studies on...
An in situ coacervative extraction (IS-CAE) based on a double-solvent supramolecular system coupled to liquid–liquid microextraction is investigated for extraction and enrichment of triazole fungicides. The formation of a double-solvent supramo...
A study was undertaken of the solvolysis of pivaloyl triflate in a variety of ionic liquid:alcohol solvent mixtures. The solvolysis is a kΔ process (i.e., a process in which ionization occurs with rearrangement), and the resulting rearranged carbocat...
Pretreatment is very important for the efficient production of value-added products from lignocellulosic biomass. However, traditional pretreatment methods have several disadvantages, including low efficiency and high pollution. This article gives an...
In this study, a green and effective extraction method was proposed to extract two main compounds, ginsenosides and polysaccharides, from American ginseng by combining deep eutectic solvents (DESs) with aqueous two-phase systems. The factors of type...
The endophytic fungus Berkleasmium sp. Dzf12, isolated from Dioscorea zingiberensis, was found to produce palmarumycins C12 and C13 which possess a great variety of biological activities. Seven biocompatible water-immiscible organic solvents includin...
Spiked centaury (Centaurium spicatum) is a well-known medicinal plant from the Mediterranean region with various bioactivities, but there are no studies addressing the use of different solvent systems to improve its pharmacological potential. Nine ex...
One of the main challenges facing the pharmaceutical industry today is the low solubility of active pharmaceutical ingredients (APIs), which leads to low bioavailability, reduced therapeutic efficacy, and the need for higher drug doses. Eutectic solv...
The determination of the NMR spin–spin relaxation rate of water in (purely) aqueous particulate dispersions has been shown to be a convenient and facile experimental approach to probing the composition of near particle surface structures. Here,...
Experimental and theoretical techniques have been developed to quantify foamy oil behaviour of solvent-heavy oil systems at bubble level during a gas exsolution process. During constant composition expansion (CCE) tests, we artificially induced foamy...
Lipases from Thermomyces lanuginosus (TLL) and Pseudomonas fluorescens (PFL) wereimmobilized on functionalized silica particles aiming their use in the synthesis of fructose oleate in a tert‐butyl alcohol/water system. Silica particles were chemicall...
Ginsenosides are the pharmacologically active constituents of ginseng. So far, more than 30 ginsenosides have been identified and widely used in pharmaceutical formulations. However, the therapeutic applications of ginsenosides are hampered by their...
Artemisinin (ART) is a sesquiterpene lactone and a popular malaria drug used in many parts of the world. Artesunate (ARTS) is a semi-synthetic derivative of ART with improved pharmacokinetic properties. However, the half-life of ARTS is less than an...
Two common extraction solvent systems, namely acidified aqueous methanol and acidified aqueous acetone, were used to extract blackberry phenolics, and the antioxidant properties of the recovered extracts were compared. The crude extracts were fractio...
3-O-ethyl l-ascorbic acid (EA), an ether derivative of Vitamin C, is widely used in skincare formulations. Previously, we reported the effects of neat solvents on EA percutaneous absorption and observed that 0.6–7.5% of the applied EA was deliv...
Innovative and sustainable all-cellulose composites (ACCs) can be obtained by partial dissolution of cellulosic fibers and regeneration of the dissolved fraction. Among cellulose solvents, sodium hydroxide/urea solutions are recognized as promising l...
Niacinamide (NIA) is the amide form of vitamin B3 and has been widely used in pharmaceutical and personal care formulations. Previously, we reported a comparative study of NIA permeation from neat solvents using the Skin Parallel Artificial Membrane...
The purification of thermo-acidic amylase enzyme from red pitaya (Hylocereus polyrhizus) peel for the first time was investigated using a novel aqueous two-phase system (ATPS) consisting of a thermo-separating copolymer and an organic solvent. The ef...
(1) Background: Aqueous two-phase systems (ATPSs) have been widely used in the separation and purification of bioactive substances in recent years. (2) Methods: In this study, deep eutectic solvents (DESs)-based ATPSs were employed for the extraction...
Currently, lipases are one of the most widely used enzymes, especially in catalysis, mostly due to their high activity in mild conditions and wide specificity. Therefore, obtaining the highest possible catalytic activity, which can be achieved throug...
A novel ethanolic two-phase system (ETPS) composed of Pluronic®L-64 (PL 64) and deep eutectic solvents (DESs) was constructed for the separation of two similar flavonoids of naringin (Nar) and neohesperidin (Neo) from the pomelo peel. The selecti...
The growing demand for more sustainable routes and processes in the mixture separation and purification industry has generated a need to search for innovations, with new solvent alternatives being a possible solution. In this context, a new class of...
In this work, solubility data of 1,5-pentanediamine adipate dihydrate in binary solvent systems of water + methanol, water + ethanol and water + N,N-dimethylformamide were experimentally measured via a static gravimetric method in the temperature ran...
The separation of large polar constituents presents a substantial challenge in natural product research when employing column chromatography techniques, as the process is both complex and time-consuming. In this study, an acetonitrile/tetrahydrofuran...
R-phycoerythrin (R-PE), a marine bioactive protein, is abundant in Porphyra yezoensis with high protein content. In this study, R-PE was purified using a deep eutectic solvents aqueous two-phase system (DES-ATPS), combined with ammonium sulphate prec...
The detailed metabolite profiling of Laguncularia racemosa was accomplished by high-performance countercurrent chromatography (HPCCC) using the three-phase system n-hexane–tert-butyl methyl ether–acetonitrile–water 2:3:3:2 (v/v/v/v) in step-gradient...
The adoption of biocatalysis in solvent-free systems is an alternative to establish a greener esters production. An interesting correlation between the acid:alcohol molar ratio and biocatalyst (immobilized lipase) loading in the optimization of ester...
Lignin as the most abundant source of aromatic chemicals in nature has attracted a great deal of attention in both academia and industry. Solvolysis is one of the promising methods to convert lignin to a number of petroleum-based aromatic chemicals....
Solvent extraction (SX) is one of the most widely applied hydrometallurgical processes in copper production from oxide ore. As the high-grade ore deposits have been developed and depleted, now only low-grade ore deposits are being developed and are t...
This study presents a novel structural modification strategy for lignin, utilizing a ternary eutectic solvent system (TESS), which induces targeted derivatization. The resulting lignin-based functional hydrogel (LBFH), prepared via rational cross-lin...
Esterification of starch was carried out to expand the usefulness of starch for a myriad of industrial applications. Lipase B from Candida antarctica, immobilized on macroporous acrylic resin (Novozym 435), was used for starch esterification in two r...
The characterization of terpene-based eutectic solvent systems is performed to describe their solid–liquid phase transitions. Physical properties are measured experimentally and compared to computed correlations for deep eutectic solvents (DES) and t...
This review provides a critical assessment of the current state of affairs regarding the solvation thermodynamics involving mixed-solvent systems. It focuses specifically on (i) its rigorous molecular-based foundations, (ii) the underlying connection...
To achieve artificial photosynthesis, it is crucial to develop a catalytic system for CO2 reduction using water as the electron source. However, photochemical CO2 reduction by homogeneous molecular catalysts has predominantly been conducted in organi...
Protein phosphorylation and dephosphorylation reactions of intracellular molecules catalyzed by enzymes such as kinases and phosphatases are essential reactions in a lot of cellular functions such as intracellular signal transduction in living system...
Traditional cleaning methods for removing undesired substances from artworks often involve the use of toxic volatile solvents, raising concerns about human health and environmental impact. Over time, various cleaning systems, such as thickeners, rigi...
Investigation of chiroptical polymers in the solution phase is paramount for designing supramolecular architectures for photonic or biomedical devices. This work is devoted to the case study of poly(propylene oxide) (PPO) optical activity in several...
Organic solvent nanofiltration (OSN), also known as solvent-resistant nanofiltration (SRNF), is an emerging membrane-based separation technique capable of efficiently separating molecules in the 200–1000 Da range within organic media. It holds...
of 79