54 Results Found

There is a critical need for detection of administrative regions through network map pictures in map censorship tasks, which can be implemented by target detection technology. However, on map images there tend to be numerous administrative regions ov...

Administrative regions are fundamental geographic elements on maps, thus making their detection in map images crucial to enhancing intelligent map interpretation. However, existing methods in this field primarily depend on the texture features within...

In recent years, many imaging systems have been developed to monitor the physiological and behavioral status of dairy cows. However, most of these systems do not have the ability to identify individual cows because the systems need to cooperate with...

Ship detection has been an area of focus for high-frequency surface wave radar (HFSWR). The detection and identification of ship formation have proven significant in early warning, while studies on the formation identification are limited due to the...

The phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling cascade is an important therapeutic target for lymphomas. Rapamycin-derivates as allosteric mTOR complex 1 (TORC1) inhibitors have shown moderate preclinical...

Recently, the field of vehicle-mounted visual intelligence technology has witnessed a surge of interest in pedestrian detection. Existing algorithms for dense pedestrian detection at intersections face challenges such as high computational weight, co...

Micro-Doppler signatures play a crucial role in capturing target features for the radar classification task, and the time–frequency distribution method is widely used to represent micro-Doppler signatures in many applications including human ac...

In high-mountain canyon areas, complex geological environments lead to frequent cascading disasters with unclear triggering mechanisms, posing severe threats to human life and property. Existing knowledge graph research in geology predominantly focus...

Soldering of printed circuit board (PCB)-based surface-mounted assemblies is a critical process, and to enhance the accuracy of detecting their multi-targeted soldering defects, we propose an automated sample generation method that combines ControlNe...

One of the most challenging issues in contemporary complex network research is to understand the structure and vulnerability of multilayer networks, even though cascading failures in single networks have been widely studied in recent years. The goal...

In the context of globalization and the Belt and Road Initiative, maintaining the stability and security of the China Railway Express network (CRN) is critical for international logistics operations. However, unexpected events can lead to node and ed...

The mitogen-activated protein kinase (MAPK) pathway is an important intracellular signaling cascade that plays a key role in various cellular processes. Understanding the regulatory mechanisms of this pathway is essential for developing effective int...

Lung cancer brain metastasis (LCBM) is a major contributor to cancer-related mortality, with a median survival of 8–16 months following diagnosis, despite advances in therapeutic strategies. The development of clinically relevant animal models...

Interactions between proteins and carbohydrates with larger biomacromolecules, e.g., lectins, are usually examined using self-assembled monolayers on target gold surfaces as a simplified model measuring setup. However, most of those measuring setups...

Thymic stromal lymphopoietin (TSLP) works synergistically with Th2 cytokines to regulate infection, inflammation, and metabolic homeostasis. However, their aberrant activities lead to the onset and sustaining of many types of allergic inflammatory di...

A cascading coaching model was used to teach bilingual speech-language pathology (SLP) graduate student clinicians and Spanish-speaking caregivers to implement naturalistic developmental behavioral intervention (NDBI) techniques with autistic prescho...

Representation learning-based hyperspectral target detection (HTD) methods generally follow a learning paradigm of single-layer or one-step representation residual learning and the target detection on original full spectral bands, which, in some case...

Auger cascades generated in high atomic number nanoparticles (NPs) following ionization were considered a potential mechanism for NP radiosensitization. In this work, we investigated the microdosimetric consequences of the Auger cascades using the th...

The integrated energy system effectively improves the comprehensive utilization of energy through cascade utilization and coordinated scheduling of various types of energy. Based on the independent integrated energy system, the thermal network intera...

Lung cancer, the leading cause of cancer-related incidence and mortality worldwide, is characterised by high invasiveness and poor prognosis. Novel therapeutic targets are required, especially for patients with inoperable metastatic disease requiring...

Chronic pain affects a significant portion of the population, with fewer than 30% achieving adequate relief from existing treatments. This study describes the humanization methodology and characterization of an effective non-opioid single-chain fragm...

The accurate mapping of crop types is crucial for ensuring food security. Remote Sensing (RS) satellite data have emerged as a promising tool in this field, offering broad spatial coverage and high temporal frequency. However, there is still a growin...

The master regulator of the fibrosis cascade is the myocardin-related transcription factor/serum response factor (MRTF/SRF) pathway, making it a key target for anti-fibrotic therapeutics. In the past, inhibitors and small interfering RNAs (siRNAs) ta...

CSP-1103 (formerly CHF5074) has been shown to reverse memory impairment and reduce amyloid plaque as well as inflammatory microglia activation in preclinical models of Alzheimer’s disease. Moreover, it was found to improve cognition and reduce brain...

Interleukine-6 plays a key role in the progression and poor survival in pancreatic ductal adenocarcinoma (PDAC). The present study aimed to clarify if targeting the interleukin-6/glycoprotein-130 signaling cascade using the small-molecule gp130 inhib...

With the wide application of distributed generation (DG) and the rapid development of alternating current/direct current (AC/DC) hybrid microgrids, the optimal planning of distributed generation connecting to AC/DC distribution networks/microgrids ha...

Vascular cognitive impairment (VCI) is the second most common cause of cognitive deficit after Alzheimer’s disease. Since VCI patients represent an important target population for prevention, an ongoing effort has been made to elucidate the pat...

This study proposed a vision-based underwater vertical docking guidance and positioning method to address docking control challenges for human-operated vehicles (HOVs) and unmanned underwater vehicles (UUVs) under complex underwater visual conditions...

Intra-amniotic infection (IAI) is one major driver for preterm birth and has been demonstrated by clinical studies to exert both beneficial and injurious effects on the premature lung, possibly due to heterogeneity in the microbial type, timing, and...

Undersea/subsea data collection via automated underwater vehicles (AUVs) plays an important role for marine biodiversity research, while it is often much more challenging than the data collection above ground via satellites or AUVs. To enable the aut...

Spinal cord injury (SCI) is a neurological condition often resulting in permanent motor and sensory deficits, for which effective treatments remain limited. RNA interference (RNAi) is a post-transcriptional mechanism of the downregulation of gene exp...

The Notch signaling pathway is an evolutionary conserved signal transduction cascade present in almost all tissues and is required for embryonic and postnatal development, as well as for stem cell maintenance, but it is also implicated in tumorigenes...

Polarization and infrared imaging technology have unique advantages for various applications ranging from biology to ocean remote sensing. However, conventional combined polarization camera and infrared camera have limitations because they are constr...

This study aims to propose a new treatment model for glioblastoma (GBM). The combination of chemotherapy, molecular targeted therapy and radiotherapy has been achieved in a highly simultaneous manner through the application of a safe, non-toxic, loca...

Accurate bud detection is a prerequisite for automatic tea picking and yield statistics; however, current research suffers from missed detection due to the variety of singleness and false detection under complex backgrounds. Traditional target detect...

Sepsis is a life-threatening condition driven by a dysregulated immune response, leading to systemic inflammation and multi-organ failure. Among the key molecular regulators, S100A8/A9 has emerged as a critical damage-associated molecular pattern (DA...

With the rapid development of global maritime trade, high-precision ship heading estimation has become crucial for maritime traffic safety and intelligent shipping. To address the challenge of heading estimation from horizontal-view optical images, t...

Dynamic wireless power systems are an effective way to supply electric vehicles (EVs) with the required power while moving and to overcome the problems of low mileage and extensive charging times. This paper targets modeling and control for future dy...

Stress-induced demyelination resulting from oligodendrocyte (OLG) dysfunction is one of the key pathological mechanisms of depression, yet its dynamic regulatory network remains unclear. This study integrates single-cell transcriptomics, lineage trac...

Non-small cell lung cancer (NSCLC) accounts for 85% of all lung cancer cases, and for the most cancer-related deaths. The survival pathway of Akt, its downstream effectors, the mammalian target of rapamycin (mTOR) and ribosomal protein S6 kinase (p70...

Background: Antibody-drug conjugates (ADCs) have ushered in a new era of precision oncology by combining the targeting specificity of monoclonal antibodies with the potent cytotoxicity of chemotherapeutic drugs. However, the cellular and molecular me...

Oxidative stress-induced neuroinflammation is the prominent feature of neurodegenerative disorders, and is characterized by a gradual decline of structure and function of neurons. Many biochemical events emerge thanks to the result of this neurodegen...

Sufficient boron-10 isotope (10B) accumulation by tumor cells is one of the main requirements for successful boron neutron capture therapy (BNCT). The inability of the clinically registered 10B-containing borophenylalanine (BPA) to maintain a high bo...

In the natural field environment, the high planting density of sorghum and severe occlusion among spikes substantially increases the difficulty of sorghum spike recognition, resulting in frequent false positives and false negatives. The target detect...

The census and management of hazard-bearing entities, along with the integrity of data quality, form crucial foundations for disaster risk assessment and zoning. By addressing the challenge of feature confusion, prevalent in single remotely sensed im...

In the pig farming environment, complex factors such as pig adhesion, occlusion, and changes in body posture pose significant challenges for segmenting multiple target pigs. To address these challenges, this study collected video data using a horizon...

The KRAS mutation is one of the leading driver mutations in colorectal cancer (CRC), and it is usually associated with poor prognosis and drug resistance. Therapies targeting the epidermal growth factor receptor (EFGR) are widely used for end-stage C...

To address the inefficiencies and limited spatial resolution of traditional single-point monitoring techniques, this study proposes a multi-scale analysis method that integrates the Multi-Scale Model-to-Model Cloud Comparison (M3C2) algorithm with le...

Pathological retinal neovascularization (RNV) is the main character of ischemic ocular diseases, which causes severe visual impairments. Though retinal microglia are well acknowledged to play important roles in both physiological and pathological ang...

Background: Gastric adenocarcinoma (GA), one of the most common gastrointestinal cancers worldwide, is often accompanied by cancer cachexia in the advanced stage owing to malnutrition and cancer-related symptoms. Although resection is the most effect...