You are currently viewing a new version of our website. To view the old version click .

46 Results Found

  • Article
  • Open Access
1 Citations
2,089 Views
27 Pages

4 September 2023

Active optics is a key technology in ground-based large-aperture telescopes. The active correction of the surface shape of the primary mirror is used to reduce the surface shape error and improve the imaging quality. At present, the structure of the...

  • Article
  • Open Access
1 Citations
1,128 Views
19 Pages

20 February 2025

Conventional mirror support structures often fail to meet optical system tolerances due to inadequate mitigation of the installation stresses caused by machining-induced surface irregularities and inclinations. This study proposes a novel single-poin...

  • Article
  • Open Access
9 Citations
3,632 Views
22 Pages

Optimization Design of Large-Aperture Primary Mirror for a Space Remote Camera

  • Xiaohan Liu,
  • Kaihui Gu,
  • Meixuan Li and
  • Zhifeng Cheng

8 June 2023

Lightweight, high stability, and high-temperature adaptability are the primary considerations when designing the primary mirror of a micro/nano satellite remote sensing camera. In this paper, the optimized design and experimental verification of the...

  • Article
  • Open Access
7 Citations
2,825 Views
20 Pages

Precision Analysis and Error Compensation of a Telescope Truss Structure Based on Robotics

  • Rui Wang,
  • Fuguo Wang,
  • Yuyan Cao,
  • Honghao Wang,
  • Xueqian Sun and
  • Fuhe Liu

15 September 2020

We propose a new secondary mirror support structure assisted by multi-robotics to improve the observation performance of vehicle-mobile telescope systems. A mathematical model of the displacement at the end of the robotic and the variation of telesco...

  • Article
  • Open Access
2 Citations
1,870 Views
14 Pages

The Optimization Design of a Lightweight 2 m SiC Mirror for Ground-Based Telescopes

  • Zhichen Wang,
  • Tao Chen,
  • Yuyan Cao,
  • Wenqiang Fan,
  • Honghao Wang and
  • Wenpan Wang

The weight of the primary mirror increases as the aperture of ground-based telescopes increases, making it more challenging to maintain the positional stability and surface accuracy of the solid primary mirror. Consequently, a 2 m lightweight silicon...

  • Article
  • Open Access
604 Views
17 Pages

16 September 2025

With the rapid advancements that are occurring in space technology, there is an increasing demand for improvements in the image quality of high-resolution space optical telescopes. The optical performance of the primary mirror plays a crucial role in...

  • Article
  • Open Access
3 Citations
1,530 Views
11 Pages

The influence of fabrication and assembly errors on the surface distortion due to gravity of a 2 m primary mirror and its correction method are presented. The effect of fabrication errors on the surface distortion is verified by Monte Carlo analysis....

  • Review
  • Open Access
5 Citations
3,086 Views
10 Pages

The Mirror Theory: Parallels between Open Angle and Angle Closure Glaucoma

  • Vasile Potop,
  • Christiana Diana Maria Dragosloveanu,
  • Alina Mihaela Ciocâlteu,
  • Miruna Gabriela Burcel,
  • Maria Cristina Marinescu and
  • Dana Margareta Cornelia Dăscălescu

12 September 2024

Glaucoma is a widespread ophthalmological disease, with a high impact and frequent visual morbidity. While the physiopathology of the two types of primary glaucoma (open angle and angle closure) has been studied, there seems to be little relationship...

  • Article
  • Open Access
1 Citations
794 Views
17 Pages

Design and Research of Large-Scale Curvature Adjustment Optical Mirror

  • Kailun Zhao,
  • Liuxing Song,
  • Dewei Sun,
  • Qiaolin Huang,
  • Rongguang Guo,
  • Guoliang Tian and
  • Jinping He

This study introduces an optimization design method for large-scale curvature-adjustable optical mirrors, innovatively integrating parametric modeling with the optimized layout of actuators, targeting the achievement of extensive curvature adjustabil...

  • Article
  • Open Access
12 Citations
3,191 Views
16 Pages

Engineering Design of an Active–Passive Combined Thermal Control Technology for an Aerial Optoelectronic Platform

  • Zhifeng Cheng,
  • Lu Sun,
  • Fuhe Liu,
  • Xiaofeng Liu,
  • Lei Li,
  • Quanchao Li and
  • Richa Hu

28 November 2019

In order to ensure the imaging performance of the aerial optoelectronic platform system in low temperature environment, an active-passive combined thermal control technology was studied. A thermal control finite element model of the aerial optoelectr...

  • Article
  • Open Access
1,389 Views
19 Pages

25 April 2025

Background: This study explored the experiences and insights of providers who support fathers experiencing family breakdown, separation, and divorce (FBSD). Methods: Nine practitioners who work for organizations in the United Kingdom supporting fathe...

  • Communication
  • Open Access
1,551 Views
13 Pages

The large-aperture space camera needs gravity unloading in the ground imaging quality test. The multi-point gravity balance method is mainly applied to the object with symmetrical structure and regular mass distribution, such as the primary mirror of...

  • Communication
  • Open Access
8 Citations
2,110 Views
13 Pages

24 January 2023

The novel rotating synthetic aperture (RSA) is a new optical imaging system that uses the method of rotating the rectangular primary mirror for dynamic imaging. It has the advantage of being lightweight, with no need for splicing and real-time surfac...

  • Article
  • Open Access
2,212 Views
13 Pages

25 November 2022

The starting point of the study is the work counselling process taking place in the induction phase of the students’ teaching career. The work counselling process consists of activities that support and strengthen the students’ teacher ho...

  • Article
  • Open Access
19 Citations
5,059 Views
13 Pages

Fast, In Vivo Model for Drug-Response Prediction in Patients with B-Cell Precursor Acute Lymphoblastic Leukemia

  • Anton Gauert,
  • Nadine Olk,
  • Helia Pimentel-Gutiérrez,
  • Kathy Astrahantseff,
  • Lasse D. Jensen,
  • Yihai Cao,
  • Angelika Eggert,
  • Cornelia Eckert and
  • Anja I.H. Hagemann

13 July 2020

Only half of patients with relapsed B-cell precursor (BCP) acute lymphoblastic leukemia (ALL) currently survive with standard treatment protocols. Predicting individual patient responses to defined drugs prior to application would help therapy strati...

  • Article
  • Open Access
756 Views
13 Pages

Sella Turcica and Cranial Base Symmetry in Anterior Synostotic Plagiocephaly Patients: A Retrospective Case–Control Study

  • Edoardo Staderini,
  • Davide Guerrieri,
  • Michele Tepedino,
  • Gianmarco Saponaro,
  • Alessandro Moro,
  • Giulio Gasparini,
  • Patrizia Gallenzi and
  • Massimo Cordaro

29 August 2025

Background/Objectives: The present case–control study aims to compare the symmetry of the sella turcica and cranial base of nine patients with anterior unicoronal synostotic plagiocephaly (ASP) and nine healthy patients referred to the maxillof...

  • Article
  • Open Access
1 Citations
2,004 Views
22 Pages

Background: This study explored the experiences of adults with diverse rare diseases (RDs) and RD caregivers with barriers and facilitators to healthcare access in the United States (US), including during the early part of the COVID-19 pandemic, and...

  • Article
  • Open Access
416 Views
15 Pages

22 October 2025

Background/Objectives: Pediatric mental health is a major public health concern worldwide and primary care providers struggle to meet the growing demand for mental healthcare. Child Psychiatry Access Programs have emerged to fill gaps in primary care...

  • Article
  • Open Access
8 Citations
2,470 Views
22 Pages

Validation of High-Availability Model for Edge Devices and IIoT

  • Peter Peniak,
  • Emília Bubeníková and
  • Alžbeta Kanáliková

18 May 2023

Competitiveness in industry requires smooth, efficient, and high-quality operation. For some industrial applications or process control and monitoring applications, it is necessary to achieve high availability and reliability because, for example, th...

  • Communication
  • Open Access
5 Citations
4,840 Views
14 Pages

Animal Research beyond the Laboratory: Report from a Workshop on Places Other than Licensed Establishments (POLEs) in the UK

  • Alexandra Palmer,
  • Beth Greenhough,
  • Pru Hobson-West,
  • Reuben Message,
  • James N. Aegerter,
  • Zoe Belshaw,
  • Ngaire Dennison,
  • Roger Dickey,
  • Julie Lane and
  • Jamie Lorimer
  • + 7 authors

13 October 2020

Research involving animals that occurs outside the laboratory raises an array of unique challenges. With regard to UK legislation, however, it receives only limited attention in terms of official guidelines, support, and statistics, which are unsurpr...

  • Article
  • Open Access
1 Citations
2,704 Views
29 Pages

24 February 2025

Effective collaboration among various actors is essential to optimally support the educational needs of gifted students. School leaders play an essential role in creating an environment and policies that foster this collaboration. This exploratory mi...

  • Article
  • Open Access
3,707 Views
33 Pages

This paper examines Gorgia Toscana (GT), a phenomenon of stop lenition observed in Tuscan varieties of Italian. Traditionally, this process has been understood to occur in post-vocalic positions, which, in the native lexicon, corresponds to onset pos...

  • Review
  • Open Access
8 Citations
2,986 Views
15 Pages

Circulating microRNAs as Diagnostic Markers in Primary Aldosteronism

  • Scott M. MacKenzie,
  • Hannah Saunders,
  • Josie C. van Kralingen,
  • Stacy Robertson,
  • Alexandra Riddell,
  • Maria-Christina Zennaro and
  • Eleanor Davies

22 October 2021

Primary aldosteronism (PA) is a common and highly treatable condition, usually resulting from adrenocortical tumorous growth or hyperplasia. PA is currently underdiagnosed owing to its complex and protracted diagnostic procedures. A simplified biomar...

  • Article
  • Open Access
5 Citations
5,263 Views
13 Pages

Isolation and Characterization of Primary DMD Pig Muscle Cells as an In Vitro Model for Preclinical Research on Duchenne Muscular Dystrophy

  • Tina Donandt,
  • Stefan Hintze,
  • Sabine Krause,
  • Eckhard Wolf,
  • Benedikt Schoser,
  • Maggie C. Walter and
  • Peter Meinke

21 October 2022

Duchenne muscular dystrophy (DMD) is the most frequent genetic myopathy in childhood and leads to progressive muscle atrophy, weakness, and premature death. So far, there is no curative treatment available. Therapeutic development from bench to bedsi...

  • Perspective
  • Open Access
4 Citations
6,576 Views
15 Pages

Does Vitamin B6 Act as an Exercise Mimetic in Skeletal Muscle?

  • Norihisa Kato,
  • Yongshou Yang,
  • Chanikan Bumrungkit and
  • Thanutchaporn Kumrungsee

15 September 2024

Marginal vitamin B6 (B6) deficiency is common in various segments worldwide. In a super-aged society, sarcopenia is a major concern and has gained significant research attention focused on healthy aging. To date, the primary interventions for sarcope...

  • Article
  • Open Access
11 Citations
3,085 Views
13 Pages

Chemotherapy and Survival in Patients with Primary High-Grade Extremity and Trunk Soft Tissue Sarcoma

  • Danielle S. Graham,
  • Ritchell van Dams,
  • Nicholas J. Jackson,
  • Mykola Onyshchenko,
  • Mark A. Eckardt,
  • Benjamin J. DiPardo,
  • Scott D. Nelson,
  • Bartosz Chmielowski,
  • Jacob E. Shabason and
  • Arun S. Singh
  • + 2 authors

24 August 2020

The use of upfront chemotherapy for primary localized soft tissue sarcoma (STS) of the extremity and trunk is debated. It remains unclear if chemotherapy adds clinical benefit, which patients are likely to benefit, and whether the timing of therapy a...

  • Communication
  • Open Access
3 Citations
1,325 Views
9 Pages

Tissue-Specific Effects of Aging on Repeat-Mediated Mutation Hotspots In Vivo

  • Alexandra M. D’Amico,
  • Tonia T. Li and
  • Karen M. Vasquez

16 November 2024

Aging constitutes complex and dynamic alterations in molecular and physiological processes and is associated with numerous disorders, in part due to increased genetic instability. The aging population is projected to double by 2050, underscoring the...

  • Article
  • Open Access
3,750 Views
20 Pages

The aging water distribution system in the United States, constructed mainly during the 1970s with some pipes dating back 125 years, is experiencing significant deterioration leading to substantial water losses. Along with the potential for water los...

  • Review
  • Open Access
290 Views
31 Pages

Modulation of Toll-like Receptors with Natural Compounds: A Therapeutic Avenue Against Inflammaging?

  • Corina Andrei,
  • Ciprian Pușcașu,
  • George Mihai Nitulescu and
  • Anca Zanfirescu

22 November 2025

Chronic low-grade inflammation, or “inflammaging,” is a defining feature of aging and a key driver of functional decline. Among innate immune sensors, Toll-like receptors (TLRs) are central mediators linking cellular stress to sterile inf...

  • Article
  • Open Access
2 Citations
2,750 Views
33 Pages

Modelling EEG Dynamics with Brain Sources

  • Vitaly Volpert,
  • Georges Sadaka,
  • Quentin Mesnildrey and
  • Anne Beuter

5 February 2024

An electroencephalogram (EEG), recorded on the surface of the scalp, serves to characterize the distribution of electric potential during brain activity. This method finds extensive application in investigating brain functioning and diagnosing variou...

  • Article
  • Open Access
1 Citations
3,131 Views
8 Pages

15 September 2023

The U.S. Army Veterinary Services (AVS) provides public health guidance, consultation, and clinical support regarding zoonoses for the Department of Defense (DoD). AVS One Health Division was tasked with developing a surveillance tool for zoonoses of...

  • Brief Report
  • Open Access
9 Citations
3,173 Views
12 Pages

Next-Generation Sequencing Comparative Analysis of DNA Mutations between Blood-Derived Extracellular Vesicles and Matched Cancer Tissue in Patients with Grade 4 Glioblastoma

  • Paolo Rosa,
  • Elena De Falco,
  • Luca Pacini,
  • Amedeo Piazza,
  • Paolo Ciracì,
  • Luca Ricciardi,
  • Francesco Fiorentino,
  • Sokol Trungu,
  • Massimo Miscusi and
  • Antonino Raco
  • + 1 author

The biological heterogeneity of glioblastoma, IDH-wildtype (GBM, CNS WHO grade 4), the most aggressive type of brain cancer, is a critical hallmark, caused by changes in the genomic mutational asset and influencing clinical progression over time. The...

  • Review
  • Open Access
1 Citations
1,770 Views
14 Pages

Seronegative Sicca Syndrome: Diagnostic Considerations and Management Strategies

  • Yordanka M. Basheva-Kraeva,
  • Krasimir I. Kraev,
  • Petar A. Uchikov,
  • Maria I. Kraeva,
  • Bozhidar K. Hristov,
  • Nina St. Stoyanova,
  • Vesela T. Mitkova-Hristova,
  • Borislav Ivanov,
  • Stanislav S. Karamitev and
  • Nina Koleva
  • + 2 authors

17 June 2025

Seronegative sicca syndrome encompasses patients who present with xerostomia and/or keratoconjunctivitis sicca but lack anti-SSA/SSB antibodies and do not fulfill current classification criteria for primary Sjögren’s syndrome (pSS). Despit...

  • Article
  • Open Access
787 Views
22 Pages

27 July 2025

To enable accurate evaluation of satellite laser communication terminals under solar outage interference, this paper presents the design and implementation of a solar radiation simulation system targeting the 1540–1560 nm communication band. Th...

  • Article
  • Open Access
4 Citations
2,814 Views
13 Pages

Development and Validation of a Non-Invasive, Chairside Oral Cavity Cancer Risk Assessment Prototype Using Machine Learning Approach

  • Neel Shimpi,
  • Ingrid Glurich,
  • Reihaneh Rostami,
  • Harshad Hegde,
  • Brent Olson and
  • Amit Acharya

11 April 2022

Oral cavity cancer (OCC) is associated with high morbidity and mortality rates when diagnosed at late stages. Early detection of increased risk provides an opportunity for implementing prevention strategies surrounding modifiable risk factors and scr...

  • Article
  • Open Access
734 Views
16 Pages

25 September 2025

This study presents the development and validation of a high-efficiency optical interface designed for ultra-high-concentration photovoltaic (UHCPV) systems, with a focus on enabling clean and sustainable solar energy conversion. A Fresnel lens serve...

  • Article
  • Open Access
9 Citations
2,113 Views
22 Pages

15 December 2023

The coal industry is a crucial component of China’s energy sector. However, the persistent exploitation of coal resources has gravely impacted the ecological environment. While the Remote Sensing Ecology Index (RSEI) is predominantly used for a...

  • Article
  • Open Access
214 Views
11 Pages

A Comparison of Functional Outcomes in Open Fractures of Phalanges, Early Versus Delayed Treatment, and Considerations on Tulipan’s Classification

  • Camillo Fulchignoni,
  • Silvia Pietramala,
  • Andrea Cruciani,
  • Alessio Greco,
  • Stella La Rocca,
  • Leopoldo Arioli,
  • Emanuele Gerace and
  • Lorenzo Rocchi

21 November 2025

Background: Open phalangeal fractures raise timing questions that may not mirror long-bone protocols. We aimed to test whether time-to-surgery is associated with infection, time to union, and return to work. Methods: A single-centre retrospective coh...

  • Review
  • Open Access
7 Citations
4,434 Views
19 Pages

28 December 2022

The search for fundamental determinants of bio-molecular chirality is a hot topic in biology, clarifying the meaning of evolution and the enigma of life’s origin. The question of origin may be resolved assuming that non-biological and biological enti...

  • Article
  • Open Access
9 Citations
3,926 Views
11 Pages

Proteins of the Ciliated Protozoan Parasite Ichthyophthirius multifiliis Identified in Common Carp Skin Mucus

  • Mona Saleh,
  • Abdel-Azeem S. Abdel-Baki,
  • Mohamed A. Dkhil,
  • Mansour El-Matbouli and
  • Saleh Al-Quraishy

The skin mucus is the fish primary defense barrier protecting from infections via the skin epidermis. In a previous study, we have investigated the proteome of common carp (Cyprinus carpio) skin mucus at two different time points (1 and 9 days) post-...

  • Article
  • Open Access
1 Citations
2,051 Views
29 Pages

15 April 2025

This research aims to develop and validate an organizational maturity framework (OM framework) to assess an organization’s maturity and improve the operational performance of the EQM. The study adopts a multi-methods approach. Qualitative data...

  • Article
  • Open Access
489 Views
18 Pages

14 October 2025

The mackerel fishery is Taiwan’s most productive coastal fishery sector, with the blue mackerel (Scomber australasicus) being its primary target species. Given the economic and ecological significance of this fishery, considerable attention has...

  • Study Protocol
  • Open Access
1,139 Views
18 Pages

ACT-ON-DIP: Study Protocol of a Randomized Controlled Trial of a Home-Based ACTion Observation Tele-RehabilitatioN for Upper Limb in Children with DIPlegic Cerebral Palsy

  • Elena Beani,
  • Elisa Matteucci,
  • Elisa Sicola,
  • Giada Martini,
  • Maria Chiara Di Lieto,
  • Clara Bombonato,
  • Valentina Menici,
  • Annalisa Cotardo,
  • Marta Rizzo and
  • Silvia Filogna
  • + 17 authors

14 September 2025

Background: Children with diplegic Cerebral Palsy often exhibit upper-limb (UL) motor impairments compounded by deficits in visuospatial, sensory, and executive functions. Despite this, research has primarily focused on lower-limb rehabilitation, lea...

  • Article
  • Open Access
796 Views
39 Pages

Harnessing Machine Learning to Analyze Renewable Energy Research in Latin America and the Caribbean

  • Javier De La Hoz-M,
  • Edwan A. Ariza-Echeverri,
  • John A. Taborda,
  • Diego Vergara and
  • Izabel F. Machado

16 October 2025

The transition to renewable energy is essential for mitigating climate change and promoting sustainable development, particularly in Latin America and the Caribbean (LAC). Despite its vast potential, the region faces structural and economic challenge...

  • Article
  • Open Access
923 Views
19 Pages

A Thymus-Independent Artificial Organoid System Supports Complete Thymopoiesis from Rhesus Macaque-Derived Hematopoietic Stem and Progenitor Cells

  • Callie Wilde,
  • Saleem Anwar,
  • Yu-Tim Yau,
  • Sunil Badve,
  • Yesim Gökmen-Polar,
  • John D. Roback,
  • Rama Rao Amara,
  • R. Paul Johnson and
  • Sheikh Abdul Rahman

Background: T cell regeneration in the thymus is intrinsically linked to the T cell-biased lineage differentiation of hematopoietic stem and progenitor cells (HSPCs). Although nonhuman primates (NHPs) serve as indispensable models for studying thymic...

  • Review
  • Open Access
1 Citations
4,849 Views
18 Pages

Frontal Fibrosing Alopecia in Men: A Review of the Literature

  • Ana Melián-Olivera,
  • Adrián Imbernón-Moya,
  • María L. Porriño-Bustamante,
  • Cristina Pindado-Ortega,
  • Daniel Fernandes-Melo and
  • David Saceda-Corralo

12 March 2025

Background: Frontal fibrosing alopecia (FFA) is a primary cicatricial alopecia, initially described in postmenopausal women but increasingly reported in men. The male form remains under-recognized, often misdiagnosed as androgenetic alopecia (AGA) or...