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52 Results Found

  • Article
  • Open Access
20 Citations
4,122 Views
17 Pages

Freshwater cyanobacterial blooms (e.g., Microcystis blooms) constitute a major global environmental problem because of their risks to public health and aquatic ecological systems. Current physicochemical treatments of toxic cyanobacteria cause the si...

  • Article
  • Open Access
5 Citations
2,789 Views
16 Pages

Microcystin-Detoxifying Recombinant Saccharomyces cerevisiae Expressing the mlrA Gene from Sphingosinicella microcystinivorans B9

  • Fernando de Godoi Silva,
  • Daiane Dias Lopes,
  • Ronald E. Hector,
  • Maikon Thiago do Nascimento,
  • Tatiana de Ávila Miguel,
  • Emília Kiyomi Kuroda,
  • Gisele Maria de Andrade de Nóbrega,
  • Ken-Ichi Harada and
  • Elisa Yoko Hirooka

Contamination of water by microcystins is a global problem. These potent hepatotoxins demand constant monitoring and control methods in potable water. Promising approaches to reduce contamination risks have focused on natural microcystin biodegradati...

  • Article
  • Open Access
6 Citations
1,974 Views
24 Pages

Towards an Improved High-Throughput Phenotyping Approach: Utilizing MLRA and Dimensionality Reduction Techniques for Transferring Hyperspectral Proximal-Based Model to Airborne Images

  • Ramin Heidarian Dehkordi,
  • Gabriele Candiani,
  • Francesco Nutini,
  • Federico Carotenuto,
  • Beniamino Gioli,
  • Carla Cesaraccio and
  • Mirco Boschetti

27 January 2024

At present, it is critical to accurately monitor wheat crops to help decision-making processes in precision agriculture. This research aims to retrieve various wheat crop traits from hyperspectral data using machine learning regression algorithms (ML...

  • Proceeding Paper
  • Open Access
1 Citations
2,596 Views
7 Pages

Modeling Water Sorption Capacity of Silica Gel

  • Dragana Kešelj,
  • Dragica Lazić,
  • Željana Bogićević,
  • Zoran Petrović and
  • Dijana Drljača

Silica gel is a widely used desiccant with a high water sorption capacity, influenced by factors such as specific surface area, pore volume, and pore size. This study develops mathematical models using multiple linear regression analysis (MLRA) to pr...

  • Article
  • Open Access
25 Citations
5,857 Views
23 Pages

Origin-Oriented Elemental Profile of Fine Ambient Particulate Matter in Central European Suburban Conditions

  • Wioletta Rogula-Kozłowska,
  • Grzegorz Majewski,
  • Barbara Błaszczak,
  • Krzysztof Klejnowski and
  • Patrycja Rogula-Kopiec

Twenty-four-hour samples of fine ambient particulate matter (PM2.5; particles with aerodynamic diameters ≤2.5 µm) were collected in a suburban (quasi-rural) area in Racibórz (Poland) between 1 January 2011 and 26 December 2012. The samples were analy...

  • Article
  • Open Access
11 Citations
3,618 Views
13 Pages

Cloning and Expression of Genes for Biodegrading Nodularin by Sphingopyxis sp. USTB-05

  • Qianqian Xu,
  • Hongfei Ma,
  • Jinhui Fan,
  • Hai Yan,
  • Haiyang Zhang,
  • Chunhua Yin,
  • Xiaolu Liu,
  • Yang Liu and
  • Huasheng Wang

20 September 2019

Biodegradation is efficient for removing cyanobacterial toxins, such as microcystins (MCs) and nodularin (NOD). However, not all the microbial strains with the microcystin-biodegrading enzymes MlrA and MlrC could biodegrade NOD. Studies on genes and...

  • Article
  • Open Access
25 Citations
4,489 Views
16 Pages

The Effect of a Combined Hydrogen Peroxide-MlrA Treatment on the Phytoplankton Community and Microcystin Concentrations in a Mesocosm Experiment in Lake Ludoš

  • Dariusz Dziga,
  • Nada Tokodi,
  • Damjana Drobac,
  • Mikołaj Kokociński,
  • Adam Antosiak,
  • Jakub Puchalski,
  • Wojciech Strzałka,
  • Mariusz Madej,
  • Zorica Svirčev and
  • Jussi Meriluoto

11 December 2019

Harmful cyanobacteria and their toxic metabolites constitute a big challenge for the production of safe drinking water. Microcystins (MC), chemically stable hepatotoxic heptapeptides, have often been involved in cyanobacterial poisoning incidents. A...

  • Article
  • Open Access
10 Citations
5,068 Views
23 Pages

Assessing Changes in Terrestrial Water Storage Components over the Great Artesian Basin Using Satellite Observations

  • Pankaj R. Kaushik,
  • Christopher E. Ndehedehe,
  • Ryan M. Burrows,
  • Mark R. Noll and
  • Mark J. Kennard

6 November 2021

The influence of climate change and anthropogenic activities (e.g., water withdrawals) on groundwater basins has gained attention recently across the globe. However, the understanding of hydrological stores (e.g., groundwater storage) in one of the l...

  • Article
  • Open Access
21 Citations
8,632 Views
22 Pages

Retrofit of Building Façade Using Precast Sandwich Panel: An Integrated Thermal and Environmental Assessment on BIM-Based LCA

  • Quddus Tushar,
  • Guomin Zhang,
  • Muhammed A. Bhuiyan,
  • Satheeskumar Navaratnam,
  • Filippo Giustozzi and
  • Lei Hou

30 November 2022

The study conducts a comprehensive life cycle assessment (LCA) of precast sandwich panels by integrating operational and embodied phases detailing thermal efficiency and environmental impacts. The analytical regression model is developed for climatic...

  • Article
  • Open Access
2 Citations
1,391 Views
16 Pages

An Advanced Approach for Predicting Workpiece Surface Roughness Using Finite Element Method and Image Processing Techniques

  • Taoming Chen,
  • Chun Li,
  • Zhexiang Zou,
  • Qi Han,
  • Bing Li,
  • Fengshou Gu and
  • Andrew D. Ball

20 November 2024

Workpiece surface quality is a critical metric for assessing machining quality. However, due to the complex coupling characteristics of cutting factors, accurately predicting surface roughness remains challenging. Typically, roughness is measured pos...

  • Article
  • Open Access
100 Citations
15,822 Views
16 Pages

Degradation of Microcystin-LR and RR by a Stenotrophomonas sp. Strain EMS Isolated from Lake Taihu, China

  • Jian Chen,
  • Liang Bin Hu,
  • Wei Zhou,
  • Shao Hua Yan,
  • Jing Dong Yang,
  • Yan Feng Xue and
  • Zhi Qi Shi

2 March 2010

A bacterial strain EMS with the capability of degrading microcystins (MCs) was isolated from Lake Taihu, China. The bacterium was tentatively identified as a Stenotrophomonas sp. The bacterium could completely consume MC-LR and MC-RR within 24 hours...

  • Article
  • Open Access
39 Citations
8,810 Views
19 Pages

4 November 2016

Harmful cyanobacteria blooms may deteriorate freshwater environments, leading to bad water quality that can adversely affect the health of humans, animals, and aquatic life. Many cyanobacteria can produce toxic metabolites, with Microcystin-LR (MC-LR...

  • Article
  • Open Access
8 Citations
3,984 Views
24 Pages

Assessing the Generalization of Machine Learning-Based Slope Failure Prediction to New Geographic Extents

  • Aaron E. Maxwell,
  • Maneesh Sharma,
  • J. Steven Kite,
  • Kurt A. Donaldson,
  • Shannon M. Maynard and
  • Caleb M. Malay

Slope failure probabilistic models generated using random forest (RF) machine learning (ML), manually interpreted incident points, and light detection and ranging (LiDAR) digital terrain variables are assessed for predicting and generalizing to new g...

  • Article
  • Open Access
17 Citations
4,375 Views
22 Pages

Retrieval of Crop Canopy Chlorophyll: Machine Learning vs. Radiative Transfer Model

  • Mir Md Tasnim Alam,
  • Anita Simic Milas,
  • Mateo Gašparović and
  • Henry Poku Osei

7 June 2024

In recent years, the utilization of machine learning algorithms and advancements in unmanned aerial vehicle (UAV) technology have caused significant shifts in remote sensing practices. In particular, the integration of machine learning with physical...

  • Article
  • Open Access
67 Citations
8,505 Views
25 Pages

7 April 2019

Leaf area index (LAI) is a crucial crop biophysical parameter that has been widely used in a variety of fields. Five state-of-the-art machine learning regression algorithms (MLRAs), namely, artificial neural network (ANN), support vector regression (...

  • Article
  • Open Access
7 Citations
5,253 Views
15 Pages

Microcystin-LR Removal from Water via Enzymatic Linearization and Ultrafiltration

  • Abelline Fionah,
  • Cannon Hackett,
  • Hazim Aljewari,
  • Laura Brady,
  • Faisal Alqhtani,
  • Isabel C. Escobar and
  • Audie K. Thompson

22 March 2022

Microcystin-LR (MC-LR) is a toxin produced by cyanobacteria that can bloom in freshwater supplies. This study describes a new strategy for remediation of MC-LR that combines linearization of the toxin using microcystinase A, MlrA, enzyme with rejecti...

  • Article
  • Open Access
1 Citations
1,362 Views
17 Pages

Biodegradation of Microcystins by Aquatic Bacteria Klebsiella spp. Isolated from Lake Kasumigaura

  • Thida Lin,
  • Kazuya Shimizu,
  • Tianxiao Liu,
  • Qintong Li and
  • Motoo Utsumi

10 July 2025

Microcystins (MCs) are the most toxic and abundant cyanotoxins found in natural waters during harmful cyanobacterial blooms. These toxins pose a significant threat to plant, animal, and human health due to their toxicity. Degradation of MCs by MC-deg...

  • Article
  • Open Access
87 Citations
11,492 Views
27 Pages

Emulation of Leaf, Canopy and Atmosphere Radiative Transfer Models for Fast Global Sensitivity Analysis

  • Jochem Verrelst,
  • Neus Sabater,
  • Juan Pablo Rivera,
  • Jordi Muñoz-Marí,
  • Jorge Vicent,
  • Gustau Camps-Valls and
  • José Moreno

19 August 2016

Physically-based radiative transfer models (RTMs) help understand the interactions of radiation with vegetation and atmosphere. However, advanced RTMs can be computationally burdensome, which makes them impractical in many real applications, especial...

  • Article
  • Open Access
7 Citations
4,548 Views
16 Pages

27 March 2022

In the USA, family-based treatment (FBT) with inpatient medical stabilization as needed is the leading evidence-based treatment for youth with anorexia nervosa (AN). In continental Europe, typically inpatient multimodal treatment targeting weight rec...

  • Article
  • Open Access
11 Citations
3,668 Views
16 Pages

18 November 2021

Currently, studies worldwide have comprehensively recognized the importance of Sphingomonadaceae bacteria and the mlrCABD gene cluster in microcystin (MC) degradation. However, knowledge about their degradation of nodularin (NOD) is still unclear. In...

  • Article
  • Open Access
49 Citations
6,927 Views
29 Pages

Assessment of Workflow Feature Selection on Forest LAI Prediction with Sentinel-2A MSI, Landsat 7 ETM+ and Landsat 8 OLI

  • Benjamin Brede,
  • Jochem Verrelst,
  • Jean-Philippe Gastellu-Etchegorry,
  • Jan G. P. W. Clevers,
  • Leo Goudzwaard,
  • Jan den Ouden,
  • Jan Verbesselt and
  • Martin Herold

12 March 2020

The European Space Agency (ESA)’s Sentinel-2A (S2A) mission is providing time series that allow the characterisation of dynamic vegetation, especially when combined with the National Aeronautics and Space Administration (NASA)/United States Geo...

  • Article
  • Open Access
67 Citations
10,799 Views
24 Pages

An Emulator Toolbox to Approximate Radiative Transfer Models with Statistical Learning

  • Juan Pablo Rivera,
  • Jochem Verrelst,
  • Jose Gómez-Dans,
  • Jordi Muñoz-Marí,
  • José Moreno and
  • Gustau Camps-Valls

22 July 2015

Physically-based radiative transfer models (RTMs) help in understanding the processes occurring on the Earth’s surface and their interactions with vegetation and atmosphere. When it comes to studying vegetation properties, RTMs allows us to study lig...

  • Article
  • Open Access
21 Citations
2,941 Views
18 Pages

Retrieval of Leaf Chlorophyll Contents (LCCs) in Litchi Based on Fractional Order Derivatives and VCPA-GA-ML Algorithms

  • Umut Hasan,
  • Kai Jia,
  • Li Wang,
  • Chongyang Wang,
  • Ziqi Shen,
  • Wenjie Yu,
  • Yishan Sun,
  • Hao Jiang,
  • Zhicong Zhang and
  • Dan Li
  • + 2 authors

21 January 2023

The accurate estimation of leaf chlorophyll content (LCC) is a significant foundation in assessing litchi photosynthetic activity and possible nutrient status. Hyperspectral remote sensing data have been widely used in agricultural quantitative monit...

  • Article
  • Open Access
33 Citations
8,999 Views
14 Pages

13 August 2014

An important aim of white (grey) biotechnology is bioremediation, where microbes are employed to remove unwanted chemicals. Microcystins (MCs) and other cyanobacterial toxins are not industrial or agricultural pollutants; however, their occurrence as...

  • Article
  • Open Access
62 Citations
8,477 Views
17 Pages

Presence or Absence of mlr Genes and Nutrient Concentrations Co-Determine the Microcystin Biodegradation Efficiency of a Natural Bacterial Community

  • María Ángeles Lezcano,
  • Jesús Morón-López,
  • Ramsy Agha,
  • Isabel López-Heras,
  • Leonor Nozal,
  • Antonio Quesada and
  • Rehab El-Shehawy

3 November 2016

The microcystin biodegradation potential of a natural bacterial community coexisting with a toxic cyanobacterial bloom was investigated in a water reservoir from central Spain. The biodegradation capacity was confirmed in all samples during the bloom...

  • Article
  • Open Access
48 Citations
7,213 Views
30 Pages

3 December 2018

Field spectra acquired from a handheld spectroradiometer and Sentinel-2 images spectra were used to investigate the applicability of hyperspectral and multispectral data in retrieving the maize leaf area index in low-input crop systems, with high spa...

  • Article
  • Open Access
8 Citations
3,252 Views
15 Pages

Genomic Analysis of Shiga Toxin-Producing E. coli O157 Cattle and Clinical Isolates from Alberta, Canada

  • Emmanuel W. Bumunang,
  • Rahat Zaheer,
  • Kim Stanford,
  • Chad Laing,
  • Dongyan Niu,
  • Le Luo Guan,
  • Linda Chui,
  • Gillian A. M. Tarr and
  • Tim A. McAllister

31 August 2022

Shiga toxin (stx) is the principal virulence factor of the foodborne pathogen, Shiga toxin-producing Escherichia coli (STEC) O157:H7 and is associated with various lambdoid bacterio (phages). A comparative genomic analysis was performed on STEC O157...

  • Review
  • Open Access
1,336 Views
29 Pages

RTM Surrogate Modeling in Optical Remote Sensing: A Review of Emulation for Vegetation and Atmosphere Applications

  • Jochem Verrelst,
  • Miguel Morata,
  • José Luis García-Soria,
  • Yilin Sun,
  • Jianbo Qi and
  • Juan Pablo Rivera-Caicedo

31 October 2025

Radiative transfer models (RTMs) are foundational to optical remote sensing for simulating vegetation and atmospheric properties. However, their significant computational cost, especially for 3D RTMs and large-scale applications, severely limits thei...

  • Feature Paper
  • Article
  • Open Access
9 Citations
4,117 Views
18 Pages

19 January 2021

Sun induced chlorophyll fluorescence (SICF) emitted by phytoplankton provides considerable insights into the vital role of the carbon productivity of the earth’s aquatic ecosystems. However, the SICF signal leaving a water body is highly affect...

  • Article
  • Open Access
41 Citations
8,371 Views
13 Pages

Characterization of Enzymatic Activity of MlrB and MlrC Proteins Involved in Bacterial Degradation of Cyanotoxins Microcystins

  • Dariusz Dziga,
  • Gabriela Zielinska,
  • Benedykt Wladyka,
  • Oliwia Bochenska,
  • Anna Maksylewicz,
  • Wojciech Strzalka and
  • Jussi Meriluoto

16 March 2016

Bacterial degradation of toxic microcystins produced by cyanobacteria is a common phenomenon. However, our understanding of the mechanisms of these processes is rudimentary. In this paper several novel discoveries regarding the action of the enzymes...

  • Article
  • Open Access
2 Citations
2,520 Views
15 Pages

17 November 2022

Water bodies in urban parks are important for scenic and recreational areas, yet algal bloom problems seriously affect public use; therefore, it is important to study the features of algal density (AD) changes and environmental driving factors (EDFs)...

  • Article
  • Open Access
8 Citations
2,386 Views
21 Pages

Coupling the PROSAIL Model and Machine Learning Approach for Canopy Parameter Estimation of Moso Bamboo Forests from UAV Hyperspectral Data

  • Yongxia Zhou,
  • Xuejian Li,
  • Chao Chen,
  • Lv Zhou,
  • Yinyin Zhao,
  • Jinjin Chen,
  • Cheng Tan,
  • Jiaqian Sun,
  • Lingjun Zhang and
  • Huaqiang Du
  • + 1 author

30 May 2024

Parameters such as the leaf area index (LAI), canopy chlorophyll content (CCH), and canopy carotenoid content (CCA) are important indicators for evaluating the ecological functions of forests. Currently, rapidly developing unmanned aerial vehicles (U...

  • Article
  • Open Access
35 Citations
10,893 Views
14 Pages

31 December 2004

A QSAR toxicity analysis has been performed for a series of 19 alkaloids with the lycoctonine skeleton. GA-MLRA (Genetic Algorithm combined with Multiple Linear Regression Analysis) technique was applied for the generation of two types of QSARs: firs...

  • Article
  • Open Access
24 Citations
9,025 Views
27 Pages

7 April 2023

Land degradation and desertification (LDD) has gained worldwide policy attention due to decline in land quality and the resultant economic burden accrued upon a vast population reliant on land-based natural capital. In India, the impacts are becoming...

  • Article
  • Open Access
55 Citations
6,285 Views
18 Pages

Assessment of Leaf Chlorophyll Content Models for Winter Wheat Using Landsat-8 Multispectral Remote Sensing Data

  • Xianfeng Zhou,
  • Jingcheng Zhang,
  • Dongmei Chen,
  • Yanbo Huang,
  • Weiping Kong,
  • Lin Yuan,
  • Huichun Ye and
  • Wenjiang Huang

11 August 2020

The leaf chlorophyll content (LCC) is a critical index to characterize crop growth conditions, photosynthetic capacity, and physiological status. Its dynamic change characteristics are of great significance for monitoring crop growth conditions and u...

  • Article
  • Open Access
2 Citations
2,711 Views
9 Pages

Purification and Mechanism of Microcystinase MlrC for Catalyzing Linearized Cyanobacterial Hepatotoxins Using Sphingopyxis sp. USTB-05

  • Qianwen Zou,
  • Junhui Teng,
  • Kunyan Wang,
  • Yiming Huang,
  • Qingbei Hu,
  • Sisi Chen,
  • Qianqian Xu,
  • Haiyang Zhang,
  • Duyuan Fang and
  • Hai Yan

31 August 2022

Cyanobacterial hepatotoxins, including microcystins (MCs) and nodularins (NODs), are widely produced, distributed and extremely hazardous to human beings and the environment. However, the catalytic mechanism of microcystinase for biodegrading cyanoba...

  • Article
  • Open Access
35 Citations
5,599 Views
14 Pages

A native, highly efficient microcystin-LR (MC-LR)-degrading bacterium named a7 was isolated from Lake Taihu and identified as Sphingopyxis sp. by 16S rDNA sequence analysis. The strain a7 could totally degrade MC-LR at a rate of 3.33 mg/(L•h), as det...

  • Article
  • Open Access
12 Citations
5,615 Views
15 Pages

18 April 2017

Quantitative structure–thermostability relationship was carried out for four series of bis(imino)pyridine iron (cobalt) complexes and α-diimine nickel complexes systems in ethylene oligo/polymerization. Three structural parameters were correlated wit...

  • Article
  • Open Access
1 Citations
1,639 Views
14 Pages

A Quantitative Structure–Activity Relationship Study of the Anabolic Activity of Ecdysteroids

  • Durbek Usmanov,
  • Ugiloy Yusupova,
  • Vladimir Syrov,
  • Gerardo M. Casanola-Martin and
  • Bakhtiyor Rasulev

Phytoecdysteroids represent a class of naturally occurring substances known for their diverse biological functions, particularly their strong ability to stimulate protein anabolism. In this study, a computational machine learning-driven quantitative...

  • Article
  • Open Access
2 Citations
1,794 Views
17 Pages

Formulation and Performance of Model Concrete in Reduced-Scale Physical Model Tests

  • Gang Zheng,
  • Boyang Xia,
  • Haizuo Zhou,
  • Yu Diao,
  • Jianyou Huang,
  • Junbo Zhang and
  • Xiaoxuan Yu

24 August 2023

The utility of geotechnical centrifuge tests depends on how correctly they predict the physical and mechanical behaviour of concrete. In this study, a model concrete material that consisted of α-gypsum plaster, fine silica sand, and water was d...

  • Article
  • Open Access
6 Citations
3,057 Views
12 Pages

Determinants Analysis Regarding Household Chemical Indoor Pollution

  • Paolo Montuori,
  • Mariagiovanna Gioia,
  • Michele Sorrentino,
  • Fabiana Di Duca,
  • Francesca Pennino,
  • Giuseppe Messineo,
  • Maria Luisa Maccauro,
  • Simonetta Riello,
  • Ugo Trama and
  • Antonio Nardone
  • + 1 author

13 March 2023

Indoor household pollution is not yet sufficiently studied in the general population. Over 4 million people die prematurely every year due to air pollution in households. This study aimed to propose quantitative data research through the administrati...

  • Article
  • Open Access
10 Citations
4,846 Views
14 Pages

Insights from a Cross-Sectional Study on Knowledge, Attitudes and Behaviors Concerning Antibiotic Use in a Large Metropolitan Area: Implications for Public Health and Policy Interventions

  • Francesca Pennino,
  • Maria Luisa Maccauro,
  • Michele Sorrentino,
  • Mariagiovanna Gioia,
  • Simonetta Riello,
  • Giuseppe Messineo,
  • Carmela Di Rosa,
  • Paolo Montuori,
  • Maria Triassi and
  • Antonio Nardone

22 September 2023

The overuse and inappropriate use of antibiotics pose a grave threat to public health, contributing significantly to the accelerated development of antimicrobial resistance (AMR) and increased rates of morbidity and mortality, making it a leading cau...

  • Article
  • Open Access
15 Citations
3,249 Views
12 Pages

16 July 2020

49 samples of propolis from different regions in China were collected and analyzed for their chemical compositions, contents of total flavonoids (TFC), total phenolic acid (TPC) and antioxidant activity. High-performance liquid chromatography (HPLC)...

  • Article
  • Open Access
14 Citations
4,271 Views
20 Pages

17 August 2018

Various regression models are currently applied to derive functional forms of operating rules for hydropower reservoirs. It is necessary to analyze and evaluate the model selecting uncertainty involved in reservoir operating rules for efficient hydro...

  • Article
  • Open Access
3 Citations
2,744 Views
22 Pages

New Multidrug Efflux Systems in a Microcystin-Degrading Bacterium Blastomonas fulva and Its Genomic Feature

  • Long Jin,
  • Chengda Cui,
  • Chengxiao Zhang,
  • So-Ra Ko,
  • Taihua Li,
  • Feng-Jie Jin,
  • Chi-Yong Ahn,
  • Hee-Mock Oh and
  • Hyung-Gwan Lee

17 September 2022

A microcystin-degrading bacterial strain, Blastomonas fulva T2, was isolated from the culture of a microalgae Microcystis. The strain B. fulva T2 is Gram-stain-negative, non-motile, aerobic, non-spore-forming and phototrophic. The cells of B. fulva T...

  • Article
  • Open Access
16 Citations
2,764 Views
19 Pages

28 September 2023

The new generation of available (i.e., PRISMA, ENMAP, DESIS) and future (i.e., ESA-CHIME, NASA-SBG) spaceborne hyperspectral missions provide unprecedented data for environmental and agricultural monitoring, such as crop trait assessment. This paper...

  • Article
  • Open Access
21 Citations
4,634 Views
12 Pages

Isolation of a Novel Microcystin-Degrading Bacterium and the Evolutionary Origin of mlr Gene Cluster

  • Lian Qin,
  • Xiaoxing Zhang,
  • Xiaoguo Chen,
  • Ke Wang,
  • Yitian Shen and
  • Dan Li

13 May 2019

The mlr-dependent biodegradation plays an essential role in the natural attenuation of microcystins (MCs) in eutrophic freshwater ecosystems. However, their evolutionary origin is still unclear due to the lack of mlr gene cluster sequences. In this s...

  • Article
  • Open Access
48 Citations
9,633 Views
19 Pages

Validation of Quantitative Structure-Activity Relationship (QSAR) Model for Photosensitizer Activity Prediction

  • Neni Frimayanti,
  • Mun Li Yam,
  • Hong Boon Lee,
  • Rozana Othman,
  • Sharifuddin M. Zain and
  • Noorsaadah Abd. Rahman

29 November 2011

Photodynamic therapy is a relatively new treatment method for cancer which utilizes a combination of oxygen, a photosensitizer and light to generate reactive singlet oxygen that eradicates tumors via direct cell-killing, vasculature damage and engage...

  • Article
  • Open Access
1,251 Views
16 Pages

Comprehensive Insight into Microcystin-Degrading Mechanism of Sphingopyxis sp. m6 Based on Mlr Enzymes

  • Qin Ding,
  • Tongtong Liu,
  • Zhuoxiao Li,
  • Rongli Sun,
  • Juan Zhang,
  • Lihong Yin and
  • Yuepu Pu

5 September 2025

Bacterial degradation is one important Microcystin (MC) removal method in the natural environment. The traditional MC-degrading pathway was proposed based on the functions of individual recombinant Mlr enzymes and the structures of the main MC-degrad...

  • Article
  • Open Access
55 Citations
9,028 Views
26 Pages

Explainable Boosting Machines for Slope Failure Spatial Predictive Modeling

  • Aaron E. Maxwell,
  • Maneesh Sharma and
  • Kurt A. Donaldson

8 December 2021

Machine learning (ML) methods, such as artificial neural networks (ANN), k-nearest neighbors (kNN), random forests (RF), support vector machines (SVM), and boosted decision trees (DTs), may offer stronger predictive performance than more traditional,...

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