Due to the advance in technology, the type of data is getting more complicated and large-scale. To analyze such complex data, more advanced technique is required. In case of omics data from two different groups, it is interesting to find significant...
While treatment of localized cutaneous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) is based on surgery, brachytherapy, which delivers a high dose of radiation to tumor tissue while sparing healthy tissue, is an alternative. Since the...
Background/Objectives: Carbon-ion radiotherapy (CIRT) is now covered by Japan’s health insurance for patients with hepatocellular carcinoma (HCC) tumors measuring ≥4 cm. However, no studies have compared intrahepatic control between CIRT and...
During heavy oil development, the gathering and transportation of low-temperature wellhead-produced fluids are often accompanied by high viscosity, pipe-wall deposition, and high flow resistance, threatening the continuous and stable operation of gat...
Background/Objectives: The historically most commonly used preoperative radiotherapy regimen for soft tissue sarcomas (STSs) consists of 50 Gray (Gy) delivered in 25 fractions over 5 weeks, achieving excellent local control, but with significant chal...
Background. Peri-operative interventional radiotherapy (POIRT) entails tumor resection, catheter implantation in the same surgery, and irradiation within the peri-operative period. It allows for maximal tumor burden reduction, better tumor bed identi...
Tailless unmanned aerial vehicles (UAVs) achieve high-agility maneuvers with flight control systems. The attainable moment set (AMS) provides critical theoretical foundations and constraints for their optimization. A computational method is proposed...
Numerous randomized trials have revealed that hyperthermia (HT) + radiotherapy or chemotherapy improves local tumor control, progression free and overall survival vs. radiotherapy or chemotherapy alone. Despite these successes, however, some individu...
This paper uses heat transfer experiments and computational fluid dynamics (CFD) simulations to investigate the conjugate heat transfer (CHT) in a high-pressure pneumatic control valve assembly. A heat transfer test rig was constructed, and time&ndas...
Background: This single-center retrospective study aimed to evaluate the efficacy and toxicity profiles of stereotactic body radiotherapy (SBRT) and surgical resection in patients with adrenal metastases originating from solid tumors. Methods/Materia...
The Rate-Controlled Constrained-Equilibrium (RCCE) method for the description of the time-dependent behavior of dynamical systems in non-equilibrium states is a general, effective, physically based method for model order reduction that was originally...
Variations in dose prescription methods in stereotactic body radiotherapy (SBRT) for early stage non-small-cell lung cancer (ES-NSCLC) make it difficult to properly compare the outcomes of published studies. We conducted a comprehensive search of the...
The primary aim of this study was to analyze studies that use electrochemotherapy (ECT) in “deep-seated” tumors in solid organs (liver, kidney, bone metastasis, pancreas, and abdomen) and understand the similarities between patient select...
In this research, we develop ordinal decision-tree-based ensemble approaches in which an objective-based information gain measure is used to select the classifying attributes. We demonstrate the applicability of the approaches using AdaBoost and rand...
Background: The AFFINITY trial (NCT05890872) is a prospective, non-randomized, open-label, single-arm study evaluating the safety, immunological impact, and preliminary efficacy of Aliya pulsed electric field ablation in patients with solid tumors. T...
In patients with early-stage or recurrent NSCLC who are unable to tolerate surgery, a benefit could derive only from a systemic therapy or another few forms of local therapy. A systematic review was performed to evaluate the feasibility and the effec...
This work presents a methodological framework for the design of a resource-aware supervisory control system for process networks with model uncertainty and communication resource constraints. The developed framework aims to balance the objective of c...
Background and objective: Although transarterial chemoembolization (TACE) has been the commonest local modality for hepatocellular carcinoma (HCC), incomplete repsonse occurs especially for tumors with a large size or difficult tumor accessment. The...
Objective: Prognosis in SNSCC remains poor mainly for local failure. Due to the rarity of this disease, and heterogeneity as to site and stage, most of the existing studies are based on the experience of individual centers; as such, data from meta-an...
Background/Objectives To evaluate the efficacy and safety of unique magnetic resonance imaging (MRI)-guided interstitial brachytherapy (ISBT) for locally advanced cervical cancer that is unsuitable for intracavitary brachytherapy (ICBT) or intracavit...
Background and Objectives: T4 nasopharyngeal carcinoma (NPC) is a locally advanced disease with a high risk of local recurrence despite advances in radiotherapy techniques. Induction chemotherapy followed by intensity-modulated radiotherapy (IMRT) is...
Soft tissue sarcomas (STS) are a rare class of tumors that originate from mesenchymal tissues and occur most frequently in the extremities, trunk, and retroperitoneum. Surgical resection with R0 margins is the primary curative treatment for most loca...
Purpose: To evaluate the long-term oncological outcomes and toxicity profile based on 24 years of follow-up in patients with localized very high-risk prostate cancer (VHR PCa) treated with a combination of high-dose-rate brachytherapy (HDR-BT) and pe...
Objective: Although local definitive radiotherapy (RT) is considered the standard of care for solitary plasmacytoma (SP), the optimal RT parameters for SP patients have not been defined. The aim of this retrospective study is to analyze the effective...
Background: Radiation-associated angiosarcoma of the breast (RAASB) is a rare, challenging disease, with surgery being the accepted basic therapeutic approach. In contrast, the role of adjuvant and systemic therapies is a subject of some controversy....
A virtual marketplace or service-providing system must ensure minimal task response times. Varying working rates among the human workers in the system can lead to longer delays for certain tasks. The waiting time in the queue is crucially affected by...
Multi-robot systems (MRS) have attracted a lot of attention from researchers due to their widespread application in various environments. However, in multi-robot collaborative search tasks, two problems often arise: sparse rewards for capturing targe...
This study aimed to evaluate the efficacy and safety of computed tomography-magnetic resonance imaging (CT-MRI)-guided multi-catheter interstitial brachytherapy for patients with bulky (≥4 cm) and high-risk, stage IIB–IVB advanced cervical c...
Introduction: According to the literature only sparse data are available on the use of high-dose-rate intraoperative brachytherapy (IOHDR-BT) as a boost to external-beam irradiation (EBRT) in combination with a wide resection in patients with high-gr...
Background and Objectives: The recently published Spine Stereotactic Radiosurgery (SSRS) ESTRO guidelines advise against treating spinal metastatic disease with a single dose equal to or smaller than 18 Gy, prioritizing local control over the potenti...
Introduction: Myxoid liposarcoma (MLPS) has been reported to be more radiosensitive compared with other soft tissue sarcomas. The main objective of the study was to assess the efficacy of hypofractionated radiotherapy (RT) in the preoperative setting...
Introduction: We conducted a systematic review to determine the optimal treatment options in patients with desmoid tumours who have declined observational management. Methods: A search was conducted of the medline and embase databases (1990 to Septem...
Background: Local recurrence in gynecological malignancies occurring in a previously irradiated field is a challenging clinical issue. The most frequent curative-intent treatment is salvage surgery. Reirradiation, using three-dimensional image-guided...
Background: Currently, 45–55% of rectal cancer patients receive preoperative chemo- radio-therapy for Locally Advanced Rectal Cancer (LARC). The idea of our study is to use Electrochemotherapy (ECT) before surgery, in patients with major clinical res...
(1) Background: To report the long-term clinical outcomes of computer-tomography (CT)-guided brachytherapy (BT) for locally advanced cervical cancer. (2) Methods: A total of 135 patients with FIGO stage IB-IVA cervical cancer treated with definitive...
Background: Brachytherapy (BT) has a major role in pediatric cancers of the lower genital tract, as part of a multimodal organ conservative strategy. Scarce data are available on the location of image-guided BT. Methods: Medical records of all consec...
This study aims to investigate the effect of dose escalation with brachytherapy (BT) as an addition to definitive chemoradiotherapy (CRT) on local control and survival in esophageal cancer. From 2001 to 2020, 183 patients with locally limited or loca...
The paper proposes a novel automatic control system for the attitude of the mini-satellites equipped with an actuator having N = 2 DGMSCMGs (Double Gimbal Magnetically Suspended Control Moment Gyros) in parallel and orthogonal configuration, as well...
(1) Background: Extraskeletal osteosarcoma (ESOS) is a malignant tumor characterized by the production of bone or bone matrix by tumor cells without any continuity into the skeletal bones. The standard treatment for localized ESOS is wide resection;...
This paper presents a local tracking control approach for DC–DC synchronous buck converters operating under randomly varying load resistance. The load variation is represented by a discrete-mode switching mechanism governed by a Markov stochast...
Cutaneous melanoma is an aggressive skin cancer. While laser therapy is established for non-melanoma skin cancers, its role in melanoma remains controversial and largely unsupported by robust clinical evidence. The gold standard for melanoma manageme...
This study explores the conventional ‘funneling’ method by introducing two extra locations beyond the virtual reality (VR) controller boundaries, terming it the extended funneling technique. Thirty-two participants engaged in a localizati...
Local likelihood methods are widely used to estimate calibration functions in conditional copula models. Recent work has established uniform stochastic equicontinuity and uniform convergence rates for local likelihood estimators of covariate-dependen...
Pancreatic ductal adenocarcinoma is one of the most aggressive tumours, with an estimated 5-year overall survival rate of 5% and median survival of 5–11 months. Approximately one third of patients die of complications due to local disease progr...
Background/Objectives: Ultra-low-dose radiotherapy (ULD-RT), an ultra-low-dose regimen delivering 4 Gy in two fractions, has emerged as a promising treatment for indolent ocular adnexal lymphoma (OAL), offering disease control with minimal toxicity....
(1) Background: Surgical resection for the removal of brain metastases often fails to prevent tumor recurrence within the surgical cavity; hence, researchers are divided as to the benefits of radiation treatment following surgical resection. This ret...
Background: Pulmonary metastasectomy and stereotactic ablative radiotherapy (SABR) are both guideline-recommended treatments for selected patients with oligometastatic colorectal pulmonary metastases. However, there is limited evidence comparing thes...
Background: Preoperative localization of non-palpable breast lesions is critical for accurate resection and margin control in breast-conserving surgery. Traditional methods, such as wire or radioguided localization, have limitations in terms of logis...
Background/Objectives: Stereotactic body radiation therapy (SBRT) has demonstrated high local control rates for inoperable early-stage lung cancers. However, 5–15% of patients experience local relapse within the irradiated volume after treatmen...
This study systematically reviews the efficacy and safety of combining transarterial embolization (TAE) with radiotherapy (RT) for managing bone metastases (BM), assessing clinical response (CR), and local control (LC). A literature search using PubM...
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