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58 Results Found

  • Article
  • Open Access
234 Views
11 Pages

6 October 2026

Background/Objective: Spleen volume can vary depending on physiological conditions, systemic diseases, and various clinical factors. However, the relationship between the anatomical changes resulting from the surgical removal of an organ adjacent to...

(This article belongs to the Special Issue Current Trends in Computed Tomography: Optimization and Clinical Practice)
  • Review
  • Open Access
5 Citations
2,382 Views
11 Pages

Extrarenal Visceral Arteries Injuries during Left Radical Nephrectomy: A 50-Year Continuing Problem

  • Marco Catarci,
  • Leonardo Antonio Montemurro,
  • Michele Benedetti,
  • Paolo Ciano and ,
  • Massimiliano Millarelli and
  • Roberto Chiappa
  • + 1 author+ 0 author

14 October 2024

Due to their proximity to the left renal hilum, injuries to the superior mesenteric artery and celiac trunk are still reported during left radical nephrectomy, whether performed via open, laparoscopic, or robotic methods. The aim of this 50-year narr...

(This article belongs to the Section Nephrology & Urology)
  • Article
  • Open Access
406 Views
16 Pages

Renal Venous Anatomy in 192 Human Kidneys: Morphometry, Hilar Topography, and Anatomical Variants

  • Stere Popescu,
  • Florin Gabriel Panculescu,
  • Florin Daniel Enache,
  • Lucian Serbanescu and ,
  • Mihai Victor Lupascu,
  • Teodor Stefan Nitu,
  • Irina Nitu,
  • Maria Sabina Neacsu,
  • Ioana Livia Suliman and
  • Andreea Cristina Costea
  • + 8 authors+ 3 authors

15 October 2026

Renal venous anatomy is relevant to nephrectomy, living-donor evaluation, and retroperitoneal surgery. Classical descriptions often present a single renal vein on each side, whereas published series show that additional veins, retroaortic and circuma...

(This article belongs to the Section Medical Imaging)
  • Case Report
  • Open Access
1 Views
2 Pages

18 January 2012

We present a case of 75-year-old man with type 2 diabetes and emphysematous pyelonephritis (EPN). The patient presented with abdominal pain, fever of undetermined origin and progressive decrease in urine output. Computerized tomography scan revealed...

  • Case Report
  • Open Access
134 Views
9 Pages

Delayed Renal Artery Stump Pseudoaneurysm and Arteriovenous Fistula Following Nephrectomy Complicated by Pulmonary Coil Migration: Successful Laparoscopic Management

  • Paulina Mizera,
  • Karol Kamil Kłosiński,
  • Joanna Maria Czyżewska,
  • Jacek Cywiński and ,
  • Zbigniew Włodzimierz Pasieka and
  • Mateusz Jęckowski
  • + 1 author+ 0 author

3 November 2026

Background: Renal arteriovenous fistula (RAVF) and renal artery pseudoaneurysm (RAP) are rare vascular complications that may occur following renal surgery, trauma, or endovascular interventions. Delayed presentation after nephrectomy is exceptionall...

(This article belongs to the Section General Surgery)
  • Article
  • Open Access
1 Citations
2,418 Views
20 Pages

17 December 2024

Background and Objectives: The role of surgery in pancreatic metastases of renal cell carcinoma (PM_RCC) is highly controversial, particularly in the context of modern systemic therapies and the conflicting results of studies published so far. This s...

(This article belongs to the Section Surgery)
  • Case Report
  • Open Access
1 Citations
3,949 Views
7 Pages

Total Exenteration En Bloc with a Nephrectomy for Locally Advanced Cervical Cancer Invading a Pelvic Kidney—A Case Report and Literature Review

  • Nicolae Bacalbasa,
  • Irina Balescu,
  • Mihaela Vilcu,
  • Simona Dima and ,
  • Camelia Diaconu,
  • Laura Iliescu,
  • Alexandru Filipescu and
  • Iulian Brezean
  • + 3 authors+ 0 author

15 January 2020

Introduction: Extended pelvic resection might be the option of choice in patients presenting locally advanced cervical cancer. However, the possibility of a co-existence of an ectopic, pelvic kidney that is invaded by such a tumor is extremely rare....

(This article belongs to the Special Issue Interdisciplinary Medicine)
  • Case Report
  • Open Access
4 Citations
2 Pages

Spontaneous Rupture of Kidney: A Rare Presentation of Nephrolithiasis

  • Poras Chaudhary,
  • Sachin Khandelwal,
  • Rana A.K. Singh and
  • Upendra C. Biswal

26 September 2012

Spontaneous rupture of kidney is a rare clinical entity. A 35-year-old female presented in emergency with left flank pain and features suggestive of haemorrhagic shock. Investigations showed rupture of kidney with perinephric haematoma. Emergency lef...

  • Review
  • Open Access
9 Citations
5,676 Views
9 Pages

Clear Cell Renal Cell Carcinoma, Diagnostic and Therapeutic Difficulties, Case Report and Literature Review

  • Weronika Stolpa,
  • Angelika Stręk-Cholewińska and
  • Agnieszka Mizia-Malarz

22 September 2022

Nephroblastoma is the most common kidney tumour in children, constitutes about 85% of cases. Although renal cell carcinoma (RCC) is the second-most common kidney malignancy in children, it constitutes only about 2–6% of all cases. Currently, th...

(This article belongs to the Section Urology & Nephrology)
  • Case Report
  • Open Access
16 Citations
7,174 Views
14 Pages

Metastatic Renal Cell Carcinoma to Pancreas: Case Series and Review of the Literature

  • Daniel Vasile Balaban,
  • Laura Coman,
  • Flavius Stefan Marin,
  • Marina Balaban and ,
  • Daniela Tabacelia,
  • Florina Vasilescu,
  • Raluca Simona Costache and
  • Mariana Jinga
  • + 3 authors+ 0 author

Metastasis to the pancreas represents a small proportion of all pancreatic malignancies. Among primary tumors that metastasize to the pancreas, renal cell carcinoma (RCC) is one of the most common causes of metastatic pancreatic lesions. We herein re...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Case Report
  • Open Access
174 Views
9 Pages

Isolated Thyroid Metastasis from High-Grade Clear Cell Renal Cell Carcinoma After Radical Nephrectomy: A Case Report

  • Constantinos Papadopoulos,
  • Konstantina Dinaki,
  • Rafail Ioannidis,
  • Ioanna Gravalidou and
  • Anna Zisi

12 October 2026

Background and Clinical Significance: Thyroid metastasis from clear cell renal cell carcinoma (ccRCC) is uncommon and may occur after radical nephrectomy despite no evidence of residual or metastatic disease at that time. Diagnosis can be challenging...

(This article belongs to the Section Otolaryngology)
  • Case Report
  • Open Access
12 Citations
4,213 Views
9 Pages

Combined Robotic Surgery for Double Renal Masses and Prostate Cancer: Myth or Reality?

  • Giovanni Cochetti,
  • Diego Cocca,
  • Stefania Maddonni,
  • Alessio Paladini and ,
  • Elena Sarti,
  • Davide Stivalini and
  • Ettore Mearini
  • + 2 authors+ 0 author

26 June 2020

With the widespread use of imaging modalities performed for the staging of prostate cancer, the incidental detection of synchronous tumors is increasing in frequency. Robotic surgery represents a technical evolution in the treatment of solid tumors o...

  • Case Report
  • Open Access
10 Citations
4,737 Views
7 Pages

Metastatic Renal Cell Carcinoma to the Soft Tissue 27 Years after Radical Nephrectomy: A Case Report

  • Caterina Marra,
  • Luigi Losco,
  • Alessandra Ceccaroni,
  • Paola Pentangelo and ,
  • Donato Troisi and
  • Carmine Alfano
  • + 1 author+ 0 author

12 January 2023

Background and Objectives: Approximately 20–40% of patients affected with renal cell carcinoma (RCC) develop either distant metastatic or locally recurring disease following radical nephrectomy. Soft tissue, skin, and the central nervous system...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
14 Citations
7,535 Views
15 Pages

MDCT Diagnosis and Staging of Xanthogranulomatous Pyelonephritis

  • Stefania Tamburrini,
  • Rosita Comune,
  • Giulia Lassandro,
  • Filomena Pezzullo and ,
  • Carlo Liguori,
  • Valeria Fiorini,
  • Stefano Giusto Picchi,
  • Marina Lugarà,
  • Dario Del Biondo and
  • Mariano Scaglione
  • + 7 authors+ 2 authors

Background: Benign nephrectomy to treat patients with renal inflammatory disease in cases of severe urinary infection represents a diagnostic and management challenge because of significant inflammatory, fibrotic, and infectious components. Among ren...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Interesting Images
  • Open Access
314 Views
5 Pages

Left Renal Vein Pseudo-Fenestration

  • Daniel Gondorf,
  • George Triantafyllou,
  • Nikolaos-Achilleas Arkoudis,
  • Georgios Velonakis and ,
  • Kostis Gyftopoulos and
  • Maria Piagkou
  • + 1 author+ 0 author

6 September 2026

We describe a rare case of LRV pseudo-fenestration in a 68-year-old female identified on contrast-enhanced multidetector computed tomography. Unlike true fenestration, in which a single vessel splits and reunites, this pseudo-fenestration resulted fr...

  • Article
  • Open Access
1 Citations
953 Views
25 Pages

Laparoscopic Living Donor Nephrectomy: Learning Curve Analysis Through 1446 Cases and Outcomes from 200 Consecutive Mastery-Phase Procedures—How I Do It

  • Fahim Kanani,
  • Moran Kozin,
  • Yael Ben Avraham,
  • Efrat Avitan and ,
  • Michael Gurevich,
  • Eviatar Nesher and
  • Aviad Gravetz
  • + 2 authors+ 0 author

9 February 2026

Background: Laparoscopic living donor nephrectomy is a standard approach for kidney procurement, yet optimal technique and learning curve trajectories remain incompletely characterized. We present a high-volume single-center experience with standardi...

(This article belongs to the Section General Surgery)
  • Case Report
  • Open Access
728 Views
12 Pages

Background and Clinical Significance: Clear cell renal cell carcinoma (ccRCC) is notorious for its aggressiveness and great propensity to metastasize to virtually any organ, with a dismal five-year survival rate. While metastases from ccRCC typically...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
5 Citations
7,600 Views
11 Pages

Superior Mesenteric Artery Injury during Robotic Radical Nephrectomy: Scenarios and Management Strategies

  • Aref S. Sayegh,
  • Luis G. Medina,
  • Anibal La Riva,
  • Laura C. Perez and ,
  • Jaime Poncel,
  • Edward Forsyth,
  • Giovanni E. Cacciamani,
  • Ben Challacombe,
  • Michael Stifelman and
  • Rene Sotelo
  • + 6 authors+ 1 author

5 January 2023

Injury to the superior mesenteric artery (SMA) is a rare, underreported, and potentially devastating complication. This study aims to propose a systematic workup to describe how to prevent and manage SMA injury in a standardized stepwise manner. Thre...

(This article belongs to the Section General Surgery)
  • Case Report
  • Open Access
2 Citations
5,377 Views
8 Pages

Successful Treatment of Renal Cell Carcinoma Associated with Hypertrophic Osteopathy in a Cat

  • Takashi Tanaka,
  • Midori Tanaka,
  • Tomoyuki Tezuka,
  • Kazumi Shimada and
  • Ryo Tanaka

20 December 2024

An eight-year-old spayed female Abyssinian cat presented with lameness. Palpation revealed swelling, heat, and a reduced range of motion in the stifle and tarsal joints in both hind limbs. A radiographic examination of both hind limbs revealed perios...

(This article belongs to the Special Issue Focus on Tumours in Pet Animals)
  • Article
  • Open Access
3 Citations
3,730 Views
18 Pages

Near Real-Time Estimation of Blood Loss and Flow–Pressure Redistribution during Unilateral Nephrectomy

  • James Cowley,
  • Justicia Kyeremeh,
  • Grant D. Stewart,
  • Xichun Luo and ,
  • Wenmiao Shu and
  • Asimina Kazakidi
  • + 1 author+ 0 author

13 September 2024

Radical or partial nephrectomy, commonly used for the treatment of kidney tumors, is a surgical procedure with a risk of high blood loss. The primary aim of this study is to quantify blood loss and elucidate the redistribution of blood flux and press...

(This article belongs to the Section Mathematical and Computational Fluid Mechanics)
  • Case Report
  • Open Access
3 Citations
2,545 Views
6 Pages

Primary Renal Angiosarcoma: Rare Tumour with Lethal Outcomes

  • Zilvinas Venclovas,
  • Aurelija Alksnyte,
  • Urte Rimsaite,
  • Tomas Navickis and ,
  • Mindaugas Jievaltas and
  • Daimantas Milonas
  • + 1 author+ 0 author

Introduction: Renal haemangioma is a benign tumour, and due to its characteristics, it must be distinguished from malignant diseases. We present a clinical case of primary renal angiosarcoma initially mistaken for haemangioma due to their similarity....

(This article belongs to the Section Oncology)
  • Article
  • Open Access
5 Citations
2,953 Views
12 Pages

Podocyte-Related Mechanisms Underlying Survival Benefit of Long-Term Angiotensin Receptor Blocker

  • Xuejing Zhu,
  • Dan Gao,
  • Vittorio Albertazzi,
  • Jianyong Zhong and ,
  • Li-Jun Ma,
  • Liping Du,
  • Yu Shyr,
  • Valentina Kon,
  • Hai-Chun Yang and
  • Agnes B. Fogo
  • + 5 authors+ 0 author

We previously found that short-term treatment (week 8 to 12 after injury) with high-dose angiotensin receptor blocker (ARB) induced the regression of existing glomerulosclerosis in 5/6 nephrectomy rats. We therefore assessed the effects of long-term...

(This article belongs to the Special Issue Molecular Mechanisms of Renal Diseases)
  • Case Report
  • Open Access
31 Citations
1,843 Views
4 Pages

Anastomosing Hemangioma of the Kidney: Radiologic and Pathologic Distinctions of a Kidney Cancer Mimic

  • P.M. Cheon,
  • R. Rebello,
  • A. Naqvi,
  • S. Popovic and ,
  • M. Bonert and
  • A. Kapoor
  • + 1 author+ 0 author

1 June 2018

Anastomosing hemangioma (AH) is a rare subtype of primary vascular tumour that can, clinically and radiologically, present similarly to malignant renal tumours such as renal cell carcinoma (RCC) and angiosarcoma. Rarely seen in the genitourinary syst...

  • Case Report
  • Open Access
14 Citations
1 Views
2 Pages

Primary Renal Synovial Sarcoma

  • Girish D. Bakhshi,
  • Arshad S. Khan,
  • Aftab S. Shaikh,
  • Mohammad Ashraf A. Khan and ,
  • Mohammad Adil A. Khan and
  • Nilofar M. Jamadar
  • + 1 author+ 0 author

30 March 2012

Primary Renal Sarcoma is rare tumor comprising only 1% of all renal tumours. Synovial sarcomas are generally deep-seated tumors arising in the proximity of large joints of adolescents and young adults and account for 5-10% of all soft tissue tumours....

  • Article
  • Open Access
8 Citations
2,307 Views
17 Pages

Extracellular Vesicles Derived from Human Liver Stem Cells Counteract Chronic Kidney Disease Development and Cardiac Dysfunction in Remnant Kidney Murine Model: The Possible Involvement of Proteases

  • Elena Ceccotti,
  • Giulia Chiabotto,
  • Massimo Cedrino,
  • Alessandro Gambella and ,
  • Luisa Delsedime,
  • Alessandra Ghigo,
  • Chiara Salio,
  • Cristina Grange,
  • Maria Beatriz Herrera Sanchez and
  • Stefania Bruno
  • + 9 authors+ 4 authors

Fibrosis is a marker of chronic kidney disease (CKD) and consists of the accumulation of the extracellular matrix (ECM) components, causing the progressive deterioration of kidney function. Human liver stem cells (HLSCs) have anti-fibrotic activity,...

(This article belongs to the Special Issue New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy)
  • Case Report
  • Open Access
6 Citations
3,996 Views
9 Pages

Renal Cell Carcinoma Presenting as Syncope due to Saddle Pulmonary Tumor Embolism

  • Mohamad K. Elajami,
  • Ephraim Mansour,
  • Hisham F. Bahmad,
  • Gerard Chaaya and ,
  • Steven DeBeer,
  • Robert Poppiti and
  • Yumna Omarzai
  • + 2 authors+ 0 author

2 December 2022

Pulmonary embolism (PE) is defined as the obstruction of the pulmonary artery or one of its branches by a blood clot, tumor, air, or fat emboli originating elsewhere in the body. A saddle PE occurs when the obstruction affects the bifurcation of the...

(This article belongs to the Section Oncology)
  • Case Report
  • Open Access
9 Citations
1,061 Views
4 Pages

Endobronchial Metastasis from Renal Cell Carcinoma as a Reason for Recurrent Pulmonary Infections

  • Serafeim Chrysikos,
  • Theodoros Karampitsakos,
  • Argyrios Tzouvelekis and
  • Katerina Dimakou

30 October 2018

Endobronchial metastases (EBM) secondary to extrathoracic malignancies are very rare. Breast cancer, colorectal cancer and renal cell carcinoma represent the most common types of cancer leading to endobronchial metastases. They usually represent a la...

  • Article
  • Open Access
6 Citations
2,472 Views
13 Pages

Beta Blockade Prevents Cardiac Morphological and Molecular Remodelling in Experimental Uremia

  • Shanmugakumar Chinnappa,
  • Azhar Maqbool,
  • Hema Viswambharan,
  • Andrew Mooney and ,
  • Laura Denby and
  • Mark Drinkhill
  • + 1 author+ 0 author

27 December 2023

Heart failure and chronic kidney disease (CKD) share several mediators of cardiac pathological remodelling. Akin to heart failure, this remodelling sets in motion a vicious cycle of progressive pathological hypertrophy and myocardial dysfunction in C...

(This article belongs to the Special Issue Molecular Pathology, Diagnostics and Therapeutics of Nephropathy 3.0)
  • Article
  • Open Access
15 Citations
5,730 Views
18 Pages

Post-Ischemic Renal Fibrosis Progression Is Halted by Delayed Contralateral Nephrectomy: The Involvement of Macrophage Activation

  • Pál Tod,
  • Eva Nora Bukosza,
  • Beáta Róka,
  • Tamás Kaucsár and ,
  • Attila Fintha,
  • Tibor Krenács,
  • Gábor Szénási and
  • Péter Hamar
  • + 3 authors+ 0 author

(1) Background: Successful treatment of acute kidney injury (AKI)-induced chronic kidney disease (CKD) is unresolved. We aimed to characterize the time-course of changes after contralateral nephrectomy (Nx) in a model of unilateral ischemic AKI-induc...

(This article belongs to the Special Issue Inflammation and Oxidative Stress in Kidney Disease)
  • Case Report
  • Open Access
3,171 Views
9 Pages

Giant Retroperitoneal Liposarcoma—A Renal Hazard

  • Raymond A. Dieter,
  • George B. Kuzycz and
  • Blake J. Carlino

1 August 2024

Retroperitoneal tumors are uncommon and may reach a large size prior to causing symptoms or being noticed by the patient or physician. A middle-aged female consulted us for care during her “terminal” illness. She had already undergone fou...

(This article belongs to the Special Issue Lower Urinary Tract Research: Rationale, Feasibility, and Design)
  • Case Report
  • Open Access
1 Citations
2,859 Views
8 Pages

Renal Embolism Associated with the Atrial Myxoma: A Case Report and Literature Review

  • Masatoshi Sega,
  • Marina Yamashita,
  • Hiroshi Maruyama,
  • Yuji Taya and ,
  • Kentaro Ohgi,
  • Rei Haraoka and
  • Kouichi Hirayama
  • + 2 authors+ 0 author

24 April 2024

Renal embolisms due to cardiac myxomas are extremely rare; the clinical course, treatment, and prognosis of this disease are not established. A 69-year-old Japanese woman who underwent a nephrectomy for renal cell carcinoma 3 years earlier was hospit...

(This article belongs to the Section Urology & Nephrology)
  • Case Report
  • Open Access
2,402 Views
7 Pages

A COVID-19 Diagnosis Like an Avalanche Triggers a Series of Adverse Events but Saves a Life in the End

  • Mateusz Iwański,
  • Aldona Sokołowska,
  • Piotr Wańczura,
  • Justyna Filipowska and
  • Katarzyna Styczkiewicz

Patients diagnosed with cancer are less frequently covered by preventive measures for cardiovascular diseases. The frequent co-occurrence of these diseases makes it necessary to apply parallel diagnostics and cardiological treatment with anti-cancer...

(This article belongs to the Special Issue Progress in Prevention and Care for Cardiovascular Diseases)
  • Case Report
  • Open Access
1 Citations
1,559 Views
9 Pages

Neuroblastoma Presenting as a Congenital Renal Mass in a Neonate: A Diagnostic Pitfall

  • Agnieszka Sokół,
  • Alicja Romaniak,
  • Iwona Dachowska-Kałwak,
  • Anna Wojtyłko and ,
  • Marzena Kozakiewicz,
  • Jan Godziński and
  • Marek Ussowicz
  • + 2 authors+ 0 author

19 February 2026

Background: Congenital renal masses in neonates are most commonly congenital mesoblastic nephroma or, less frequently, or Wilms tumor. We describe a neonate with an apparent primary renal tumor that proved to be adrenal neuroblastoma infiltrating the...

(This article belongs to the Section Pediatric Hematology & Oncology)
  • Case Report
  • Open Access
1,618 Views
15 Pages

Triple Synchronous Primary Malignant Tumors of the Liver, Kidney, and Lung in a Male Patient: Case Report and Systematic Review

  • Alexandru Vlad Oprița,
  • Eduard Achim,
  • Cornelia Nițipir,
  • Nicolae Boleac and ,
  • Alissia-Nicoleta Pilatec and
  • Florin Andrei Grama
  • + 1 author+ 0 author

12 December 2025

Background: Triple primary malignant tumors (TPMTs) are extremely rare and represent a major diagnostic and therapeutic challenge. Their frequency has increased with advances in cancer detection and longer patient survival. Case presentation: We repo...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Article
  • Open Access
2 Citations
2,152 Views
12 Pages

Mitochondrial Dysfunction and Ion Imbalance in a Rat Model of Hemodialysis-Induced Myocardial Stunning

  • Yuxin Nie,
  • Liyu Lin,
  • Qiang Yang,
  • Jiachang Hu and ,
  • Minmin Sun,
  • Fangfang Xiang,
  • Xuesen Cao,
  • Jinbo Yu,
  • Yaqiong Wang and
  • Zhen Zhang
  • + 8 authors+ 3 authors

Background/Objectives: Hemodialysis-induced myocardial stunning (HIMS) is a frequent complication in patients undergoing maintenance hemodialysis, characterized by transient left ventricular dysfunction due to ischemic episodes. Mitochondrial dysfunc...

(This article belongs to the Special Issue Cardiovascular and Metabolic Disease: New Treatment and Future Directions—the 3rd Edition)
  • Case Report
  • Open Access
2 Citations
4,053 Views
8 Pages

Inferior Vena Cava (IVC) Resections without Reconstruction in Renal Tumors: Two Case Reports

  • Bogdan Moldovan,
  • Victor S. Costache,
  • Irina Modrigan,
  • Felix Farcas and ,
  • Eugeniu Banu,
  • Vlad Untaru,
  • Doly Stoica,
  • Madalina Crisan,
  • Andreea Popianas and
  • Liliana Vecerzan
  • + 8 authors+ 3 authors

(1) Background: We aim to present our experience with resection of the inferior vena cava (IVC) without reconstruction in two patients diagnosed with renal tumors. (2) Case Report: The first case was diagnosed with right renal vein sarcoma and the se...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
314 Views
20 Pages

Nutritional Programming via Maternal Protein Restriction Mitigates Long-Term Consequences of Acute Kidney Injury

  • Luis Enrique García-Ortuño,
  • Karla Barragán,
  • Rebecca Caldiño-Bhon,
  • Emma Luna and ,
  • Rosalba Pérez-Villalva and
  • Norma A. Bobadilla
  • + 1 author+ 0 author

10 October 2026

The kidney is highly sensitive to prenatal and early-life environmental influences. Maternal protein restriction (MPR) can alter renal development and may modify susceptibility to chronic kidney disease (CKD) following acute kidney injury (AKI). We i...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Article
  • Open Access
2,208 Views
21 Pages

Differential Myocardial Responses in Male and Female Rats with Uremic Cardiomyopathy

  • Beáta Bódi,
  • Rebeka Rita Vágó,
  • László Nagy,
  • Arnold Péter Ráduly and ,
  • András Gulyás,
  • Klaudia Kupecz,
  • Lilian Azar,
  • Fanni Magdolna Márványkövi,
  • Gergő Szűcs and
  • Márta Sárközy
  • + 9 authors+ 4 authors

Uremic cardiomyopathy, characterized by diastolic dysfunction, left ventricular hypertrophy (LVH), and fibrosis, is a common cardiovascular complication of chronic kidney disease (CKD). Men are at a higher risk for cardiovascular and renal diseases,...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Case Report
  • Open Access
4 Citations
1,614 Views
11 Pages

Prenatal Diagnosis of Vaginal Ectopic Ureter Insertion—Case Outcome and Literature Overview

  • Iulian Gabriel Goidescu,
  • Georgiana Nemeti,
  • Adelina Staicu,
  • Mihai Surcel and ,
  • Cerasela Mihaela Goidescu,
  • Ioana Cristina Rotar,
  • Gheorghe Cruciat and
  • Daniel Muresan
  • + 3 authors+ 0 author

Background and clinical significance: Ectopic ureters are a rare urinary tract malformation, typically diagnosed in childhood and infrequently in adulthood. The prenatal detection by ultrasound and magnetic resonance imaging (MRI) of this clinical en...

(This article belongs to the Special Issue Advances in Fetal Diagnosis and Therapy)
  • Article
  • Open Access
10 Citations
3,842 Views
14 Pages

Therapeutic Ultrasound Halts Progression of Chronic Kidney Disease In Vivo via the Regulation of Markers Associated with Renal Epithelial–Mesenchymal Transition and Senescence

  • Chen-Yu Lin,
  • Ching-Chia Wang,
  • Jui-Zhi Loh,
  • Tsai-Chen Chiang and ,
  • Te-I Weng,
  • Ding-Cheng Chan,
  • Kuan-Yu Hung,
  • Chih-Kang Chiang and
  • Shing-Hwa Liu
  • + 4 authors+ 0 author

2 November 2022

Low-intensity pulsed ultrasound (LIPUS), a therapeutic type of ultrasound, is known to enhance bone fracture repair processes and help some tissues to heal. Here, we investigated the therapeutic potential of LIPUS for the treatment of chronic kidney...

(This article belongs to the Special Issue Aging and Senescence 3.0)
  • Case Report
  • Open Access
2 Citations
2,664 Views
7 Pages

Synchronous Seminoma of Testis and Renal Cell Carcinoma: A Rare Case Report

  • Stasys Auskalnis,
  • Rasa Janciauskiene,
  • Urte Rimsaite,
  • Aurelija Alksnyte and
  • Rasa Ugenskiene

23 September 2024

Background and Objectives: Seminoma is the most common solid malignant tumour in young men. Clear-cell kidney carcinoma is the most common malignancy of the genitourinary tract. However, the synchronous occurrence of both of these tumours is rare. Ca...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
2 Citations
1,487 Views
13 Pages

Post-Nephrectomy Orchialgia: A Cross-Sectional Assessment of an Underreported Complication in Living Kidney Donors

  • Aviad Gravetz,
  • Fahim Kanani,
  • Karin Lifshitz,
  • Vladimir Tennak and ,
  • Dana Bielopolski and
  • Eviatar Nesher
  • + 1 author+ 0 author

16 August 2025

Background/Objectives: Orchialgia following kidney donation is an underrecognized complication with reported incidence varying dramatically between retrospective (2–3%) and prospective (44–55%) studies, suggesting significant underreporti...

(This article belongs to the Special Issue Clinical Advances in Kidney Transplantation)
  • Article
  • Open Access
5 Citations
2,452 Views
12 Pages

Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions

  • Maxime Schleef,
  • Margaux Rozes,
  • Bruno Pillot,
  • Gabriel Bidaux and ,
  • Fitsum Guebre-Egziabher,
  • Laurent Juillard,
  • Delphine Baetz and
  • Sandrine Lemoine
  • + 3 authors+ 0 author

Cyclosporine A (CsA) preconditioning is known to target mitochondrial permeability transition pore and protect renal function after ischemia reperfusion (IR). The upregulation of heat-shock protein 70 (Hsp70) expression after CsA injection is thought...

(This article belongs to the Special Issue Ischemia Reperfusion Injury: A Cell Signaling Crossroads and Therapeutics)
  • Case Report
  • Open Access
496 Views
13 Pages

Massive Unilateral Pyonephrosis with Extreme Leukocytosis in a Cat: A Case Report

  • Martyna Małż,
  • Magdalena Morawska and
  • Krystyna Makowska

20 August 2026

Pyonephrosis is a rare, life-threatening suppurative disease of the kidney characterised by the accumulation of purulent exudate within the renal pelvis and the destruction of renal parenchyma. It is typically associated with azotaemia and urinary tr...

(This article belongs to the Section Companion Animals)
  • Case Report
  • Open Access
7 Citations
3,113 Views
7 Pages

Genomic and Clinical Correlates of Adrenocortical Carcinoma in an Adult Patient with Li-Fraumeni Syndrome: A Case Report

  • Suraya Bondy,
  • Camilla Tajzler,
  • Sebastien J. Hotte,
  • Anil Kapoor and ,
  • Kevin Zbuk and
  • Aly-Khan A. Lalani
  • + 1 author+ 0 author

31 December 2020

Li-Fraumeni Syndrome (LFS) is defined by germline mutations of the p53 tumour suppressor gene. Adrenocortical carcinoma (ACC) is a rare aggressive malignancy that is commonly associated with LFS. Most LFS-linked ACC cases occur in children, and limit...

  • Article
  • Open Access
5 Citations
3,457 Views
19 Pages

Upregulation of Mineralocorticoid Receptor Contributes to Development of Salt-Sensitive Hypertension after Ischemia–Reperfusion Injury in Rats

  • Takumi Matsumoto,
  • Shigehiro Doi,
  • Ayumu Nakashima,
  • Takeshi Ike and ,
  • Kensuke Sasaki and
  • Takao Masaki
  • + 1 author+ 0 author

The ischemia–reperfusion injury (IRI) of rat kidneys is used as a model of acute kidney injury. Salt-sensitive hypertension occurs in rats after IRI, and the distal nephrons play important roles in the development of this condition. We investig...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
3 Citations
2,505 Views
10 Pages

Early-Branched Short Renal Arteries Are False Multiple Renal Arteries

  • Adelina Maria Jianu,
  • Nawwaf Sebastian Damen,
  • Monica Adriana Vaida,
  • Laura Octavia Grigoriță and ,
  • Marius Ioan Rusu and
  • Mugurel Constantin Rusu
  • + 1 author+ 0 author

Background/Objectives: During retroperitoneal surgery, awareness of the anatomic variants of renal arteries (RAs) is essential. We aimed to determine the prevalence of early-branched (short) Ras, the bilateral morphologies of RAs in such cases, and t...

(This article belongs to the Special Issue Clinical Impacts and Value of Anatomy)
  • Case Report
  • Open Access
5 Citations
5,077 Views
13 Pages

Adrenal Gland Primary Neuroblastoma in an Adult Patient: A Case Report and Literature Review

  • Teodora Telecan,
  • Iulia Andras,
  • Maria Raluca Bungardean,
  • Diana Muntean and ,
  • Claudia Militaru,
  • Ion Perciuleac,
  • Andrei Maga and
  • Nicolae Crisan
  • + 3 authors+ 0 author

23 December 2022

Neuroblastoma (NB) is an undifferentiated malignant tumor of the sympathetic ganglia, occurring in children under 5 years of age. However, it is a rare histology in adult patients, occurring once per every 10 million patients per year. We present the...

(This article belongs to the Special Issue Advances in Cancer Therapy from Research to Clinical Practice—Surgical, Molecular or Systemic Management of Cancer)
  • Article
  • Open Access
2 Citations
667 Views
16 Pages

Extreme Variability of the Kidney Hilar Architecture: A Radioanatomical Map to Guide Surgical Approaches

  • Daniel Gondorf,
  • George Triantafyllou,
  • Ioannis Paschopoulos,
  • Nikolaos-Achilleas Arkoudis and ,
  • Georgios Velonakis,
  • Panagiotis Kokoropoulos,
  • Nikolaos Arkadopoulos and
  • Maria Piagkou
  • + 3 authors+ 0 author

Background: Retroperitoneal surgical corridors, particularly in robotic-assisted partial nephrectomy and donor surgery, require precise knowledge of hilar vascular orientation. The typically described Vein–Artery–Pelvis (VAP) anatomy is o...

(This article belongs to the Special Issue Advances in Clinical Anatomy: Morphometric Analysis and Diagnostic Relevance)
  • Case Report
  • Open Access
410 Views
10 Pages

3 August 2026

Background and Clinical Significance: Endoscopic ureterocele incision is the preferred initial treatment for ureteroceles associated with duplex collecting systems due to its capability for rapid decompression via a minimally invasive technique with...

(This article belongs to the Special Issue When Urology Surprises: Educational and Rare Clinical Cases)

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