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  • Review
  • Open Access
56 Citations
6,500 Views
12 Pages

Cleaning Efficacy of the XP-Endo® Finisher Instrument Compared to Other Irrigation Activation Procedures: A Systematic Review

  • Dorina Lauritano,
  • Giulia Moreo,
  • Francesco Carinci,
  • Fedora Della Vella,
  • Federica Di Spirito,
  • Ludovico Sbordone and
  • Massimo Petruzzi

20 November 2019

Background. One of the most important aims of an endodontic treatment is to obtain the complete removal or reduction of root canal remaining filling material: Smear layer, bacteria, intra-canal medicaments. To meet this requirement, several irrigatio...

  • Article
  • Open Access
635 Views
13 Pages

28 August 2026

This study evaluated and compared four irrigation activation protocols—conventional syringe irrigation (CSI), passive ultrasonic irrigation (PUI), photon-induced photoacoustic streaming (PIPS), and shock wave-enhanced emission photoacoustic str...

(This article belongs to the Special Issue Functional Polymer Materials and Coatings for Next-Generation Biomedical Applications)
  • Article
  • Open Access
333 Views
14 Pages

14 September 2026

Background: Successful root canal treatment depends on achieving an effective three-dimensional seal and limiting microbial persistence and reinfection. Dentinal tubule penetration may enhance sealing by increasing sealer–dentin contact and mic...

  • Systematic Review
  • Open Access
384 Views
17 Pages

Influence of Final Irrigation on Calcium Silicate-Based Sealer Dentinal Tubular Penetration: A Systematic Review

  • Jordi Gómez-González,
  • Daniela Fernández-Negrete,
  • José Luis Sanz,
  • James Ghilotti,
  • Sofía Folguera and
  • Adrián Lozano

22 June 2026

The aim of this systematic review was to assess the influence of different final irrigation protocols and activation methods on the dentinal tubular penetration of calcium silicate-based sealers (CSSs). The review followed the PRISMA 2020 guidelines,...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
5 Citations
4,518 Views
12 Pages

14 January 2024

This study aimed to assess the penetration of AH-Plus (AHP) and AH-Plus Bioceramic (AHPB) sealers into dentinal tubules subsequent to different irrigation activation protocols. One hundred fifty teeth were divided into five groups according to the fi...

(This article belongs to the Special Issue Research on Endodontic Treatment Methods and Materials)
  • Article
  • Open Access
3,734 Views
10 Pages

Investigating the Antibacterial Ability of Sodium Hypochlorite Solution Activated with PUI and XPF File Against Enterococcus faecalis Using CFU, RT-PCR, and SEM

  • Radovan Jovanović,
  • Jugoslav Ilić,
  • Ljiljana Šubarić,
  • Zoran Vlahović,
  • Sanja Simić,
  • Zoran Arsić,
  • Milena Radunović and
  • Branka Popović

Eradication of microorganisms present in the root canal system during endodontic therapy is one of the critical factors affecting the final outcome of endodontic treatment. However, even adequate technique of the root canal treatment and use of irrig...

(This article belongs to the Section Biochemical Engineering)
  • Review
  • Open Access
4 Citations
1,862 Views
28 Pages

Modern Endodontic Irrigation and Activation: From Disinfection to Dentin Substrate Conditioning—A Narrative Review

  • Angelo Aliberti,
  • Mirko Piscopo,
  • Roberta Gasparro,
  • Gilberto Sammartino,
  • Oreste Trosino,
  • Francesco Riccitiello and
  • Pietro Ausiello

7 May 2026

Root canal disinfection remains challenging due to anatomical complexity and the limitations of mechanical instrumentation. Evidence on irrigation is often fragmented and focused on isolated outcomes, limiting clinically integrated protocols. This na...

(This article belongs to the Special Issue Contemporary Endodontic Strategies: Materials and Techniques)
  • Review
  • Open Access
9 Citations
5,006 Views
16 Pages

Evaluating the Preventive and Therapeutic Roles of Active Irrigation Systems in Root Canal Treatment: A Narrative Review and Critical Appraisal of Theory and Methodology

  • Ignacio Barbero-Navarro,
  • Iuliana Sofian-Pauliuc,
  • Maria Esther Irigoyen-Camacho,
  • Marco Antonio Zepeda-Zepeda,
  • David Ribas-Perez and
  • Antonio Luis Castaño-Seiquer

26 December 2024

Endodontic therapy aims at preventing or curing apical periodontitis. To conduct this, the cleaning and shaping of the canals are essential. By using an irrigant, such as sodium hypochlorite (NaOCl), practitioners attempt to wash out debris, dissolve...

(This article belongs to the Topic Advances in Dental Health)
  • Article
  • Open Access
12 Citations
3,961 Views
8 Pages

Effectiveness of Different Irrigant Activation Systems on Smear Layer Removal: A Scanning Electron Microscopic Study

  • Ramón Miguéns-Vila,
  • Benjamín Martín-Biedma,
  • Saleta Aboy-Pazos,
  • David Uroz-Torres,
  • Pablo Álvarez-Nóvoa,
  • Ana Belén Dablanca-Blanco,
  • Iván Varela-Aneiros and
  • Pablo Castelo-Baz

15 February 2022

The aim of this study was to evaluate the effectiveness of smear layer removal after the use of different irrigation methods (passive ultrasonic irrigation (PUI), continuous ultrasonic irrigation (CUI), apical negative pressure irrigation and convent...

(This article belongs to the Topic New Frontiers and Boundaries in the Use of Biomaterials in Dentistry)
  • Article
  • Open Access
186 Views
15 Pages

Effects of Endodontic Irrigants on Elastic Modulus and Host-Derived Endogenous Enzymatic Activity of Radicular Dentin

  • Ecehan Hazar,
  • Ahmet Hazar,
  • Roda Seseogullari-Dirihan and
  • Arzu Tezvergil-Mutluay

27 September 2026

Background/Objectives: This study evaluated the effects of endodontic irrigation protocols on the apparent elastic modulus and post-treatment total endogenous matrix metalloproteinase (MMP) activity of mineralized radicular dentin. Methods: Radicular...

(This article belongs to the Special Issue Current and Future Development Trends of Materials and Advanced Technologies Used in Endodontics)
  • Review
  • Open Access
29 Citations
18,458 Views
12 Pages

Narrative Review on Methods of Activating Irrigation Liquids for Root Canal Treatment

  • Martyna Raducka,
  • Aleksandra Piszko,
  • Paweł J. Piszko,
  • Natalia Jawor,
  • Maciej Dobrzyński,
  • Wojciech Grzebieluch,
  • Marcin Mikulewicz and
  • Katarzyna Skośkiewicz-Malinowska

30 June 2023

As indicated by standards of modern dentistry, the essence of endodontic treatment is chemo-mechanical disinfection of the root canal system. The vital element of this process is the irrigation of canals with designated solutions as well as activatin...

(This article belongs to the Section Applied Dentistry and Oral Sciences)
  • Article
  • Open Access
38 Citations
10,064 Views
17 Pages

Environment Control with Low-Cost Microcontrollers and Microprocessors: Application for Green Walls

  • Yair Andrey Rivas-Sánchez,
  • María Fátima Moreno-Pérez and
  • José Roldán-Cañas

2 February 2019

Green wall irrigation procedures are a particularly important and hard task, given that the quality of the green wall depends on them. There is currently a wide variety of irrigation programmers available, with a range of functions and prices, thereb...

(This article belongs to the Special Issue Application of Low-cost Sensors for Environmental Exposure Assessment and Mitigation)
  • Article
  • Open Access
1 Citations
2,034 Views
13 Pages

How Does Ethylenediaminetetraacetic Acid Irrigation Affect Biodentine? A Multimethod Ex Vivo Study

  • Katarzyna Dąbrowska,
  • Aleksandra Palatyńska-Ulatowska and
  • Leszek Klimek

7 March 2024

The activity of biomaterials used during endodontic treatment can be affected by various factors. One of them is the chemical action of the irrigant that they are exposed to. The aim of this multimethod ex vivo study was to evaluate the influence of...

(This article belongs to the Special Issue Recent Research in Restorative Dental Materials)
  • Article
  • Open Access
724 Views
18 Pages

Removal of a Calcium Silicate-Based Sealer from Oval Root Canals Using Different Irrigation Activation Techniques: A Stereomicroscopic and SEM–EDS Study

  • Mihai Merfea,
  • Sanda Ileana Cimpean,
  • Ioana Sofia Pop-Ciutrila,
  • Elie Assaf,
  • Ada Gabriela Delean,
  • Iulia Clara Badea,
  • Stanca Cuc and
  • Vasile-Adrian Surdu

10 April 2026

Calcium silicate-based sealers are widely used in contemporary endodontics, but their strong interaction with dentinal substrates may complicate their removal during nonsurgical retreatment and potentially hinder canal disinfection. This ex vivo stud...

(This article belongs to the Special Issue Recent Developments in Endodontics and Dental Materials)
  • Review
  • Open Access
19 Citations
12,184 Views
25 Pages

Effectiveness of Irrigation Protocols in Endodontic Therapy: An Umbrella Review

  • Manuel J. Orozco-Gallego,
  • Eliana L. Pineda-Vélez,
  • Wilder J. Rojas-Gutiérrez,
  • Martha L. Rincón-Rodríguez and
  • Andrés A. Agudelo-Suárez

18 June 2025

Background: With the inclusion of evidence-based dentistry, numerous systematic reviews (SRs) and meta-analyses (MAs) have been conducted in endodontics with the best available scientific evidence to improve diagnosis and treatment. Objective: To syn...

(This article belongs to the Special Issue Endodontics: From Technique to Regeneration)
  • Article
  • Open Access
2,658 Views
14 Pages

29 April 2025

Background: Pulp tissue debridement and the eradication of microorganisms from an infected root canal system before obturation is a primary focus of endodontic treatment and the best predictor for the long-term success of endodontic treatment. Object...

(This article belongs to the Special Issue Endodontics: From Technique to Regeneration)
  • Article
  • Open Access
1 Citations
1,561 Views
14 Pages

Comparative Analysis of the Chelating Capacity of Two Solutions Activated with Sonic and Ultrasonic Systems: HEBP Versus EDTA

  • Chloé Lefevre,
  • Julia Mena-Gómez,
  • Andrea Martin-Vacas,
  • Vicente Vera-Gónzalez and
  • Jesús Mena-Álvarez

12 September 2025

The success of root canal treatment depends on the proper execution of each phase. However, the instrumentation and irrigation phase is especially important. During this phase, the interior of the root canal system must be removed to facilitate the n...

  • Article
  • Open Access
3 Citations
2,492 Views
17 Pages

Photon-Induced Photo-Acoustic Streaming vs. Shock Wave-Enhanced Emission Photo-Acoustic Streaming—The Effect of Three Final Irrigation Protocols on the Bond Strength of an Individually Formed Fiber Post

  • Cassandra Lupita,
  • Daliana Emanuela Bojoga,
  • Alessandro Del Vecchio,
  • Dan Ioan Stoia,
  • Ion Grozav,
  • Mariana Ioana Miron and
  • Darinca Carmen Todea

26 July 2024

(1) Background: This study aimed to evaluate how laser-activated irrigation (LAI) influences the retention of a fiber post when used before an endodontic filling, as well as after post space preparation. (2) Materials and Methods: Sixty freshly extra...

(This article belongs to the Special Issue Feature Papers in Restorative Dentistry, Endodontology and Traumatology)
  • Article
  • Open Access
2 Citations
1,018 Views
13 Pages

23 January 2026

Background/Objectives: This study evaluates the penetration of a calcium silicate-based sealer (BC Universal) into dentinal tubules after different final irrigation protocols. Methods: Eighty-four single-rooted extracted teeth were instrumented with...

(This article belongs to the Special Issue Clinical Advances in Endodontic Dentistry)
  • Article
  • Open Access
19 Citations
4,491 Views
10 Pages

Impact of Final Irrigation Protocol on the Push-Out Bond Strength of Two Types of Endodontic Sealers

  • Germain Sfeir,
  • Frédéric Bukiet,
  • Wajih Hage,
  • Roula El Hachem and
  • Carla Zogheib

21 February 2023

Aim: The aim of this study was to assess the impact of the final irrigation protocol on the push-out bond strength of calcium silicate-based sealers when compared to an epoxy resin-based sealer. Materials and Methods: Eighty-four single-rooted mandib...

(This article belongs to the Special Issue Silicate Materials: Preparation, Characterization and Applications)
  • Article
  • Open Access
1 Citations
3,120 Views
10 Pages

Evaluation of Biodentine Tricalcium Silicate-Based Cement after Chlorhexidine Irrigation

  • Katarzyna Dąbrowska,
  • Aleksandra Palatyńska-Ulatowska and
  • Leszek Klimek

26 September 2024

The effectiveness of biocements applied in specialistic endodontic procedures can be influenced by multiple factors, including the postplacement chemical action of the irrigating solution. This in vitro study aimed to assess the impact of 2% chlorhex...

  • Article
  • Open Access
11 Citations
4,318 Views
14 Pages

Effectiveness of Different Final Irrigation Procedures on Enterococcus faecalis Infected Root Canals: An In Vitro Evaluation

  • Sanda Ileana Cîmpean,
  • Ioana-Sofia Pop-Ciutrila,
  • Sebastian-Roberto Matei,
  • Ioana Alina Colosi,
  • Carmen Costache,
  • Gheorghe Zsolt Nicula,
  • Iulia Clara Badea and
  • Loredana Colceriu Burtea

27 September 2022

This study aimed to evaluate the antibacterial effect of three final irrigation protocols and to compare their ability to remove the smear layer and debris from the root canal. Methods: Sixty-three single-rooted human teeth were inoculated with Enter...

(This article belongs to the Special Issue Mechanical and Metallurgical Behavior of Endodontic & Restorative Materials)
  • Brief Report
  • Open Access
7 Citations
3,702 Views
8 Pages

Histological Evaluation of Root Canals by Performing a New Cleaning Protocol “RUA” in Endodontic Surgery

  • Alfredo Iandolo,
  • Alessandra Amato,
  • Massimo Pisano,
  • Giuseppe Sangiovanni,
  • Dina Abdellatif,
  • Roberto Fornara and
  • Michele Simeone

9 March 2023

Aim: To enhance cleaning during retro-preparation in endodontic microsurgery. Materials and Methods: Forty mandibular premolars were instrumented, filled with a single cone technique, and then retro-preparation was performed and assigned to experimen...

(This article belongs to the Special Issue Modern Endodontics)
  • Systematic Review
  • Open Access
634 Views
20 Pages

Prognosis of Periapical Lesions Treated by Activated Disinfection (PUI, Laser) Without the Use of Systemic Antibiotics: Systematic Review and Meta-Analysis

  • Paula Fernández-Moreno,
  • Victoria Areal-Quecuty,
  • Carlos Segura-Raya,
  • Juan J. Saúco-Márquez,
  • Benito Sánchez-Domínguez,
  • Milagros Martín-Jiménez,
  • Juan J. Segura-Egea and
  • María León-López

9 July 2026

Background/Objectives: Activated irrigation techniques improve intracanal disinfection, but their impact on the clinical and radiographic healing of apical periodontitis remains unclear. This systematic review and meta-analysis evaluated the efficacy...

(This article belongs to the Special Issue New Clinical Advancements in Endodontics)
  • Article
  • Open Access
427 Views
18 Pages

Complementary Time-Kill Activity Displayed by Povidone-Iodine and Hydrogen Peroxide Against Shoulder Arthroplasty–Associated Pathogens, Envisaging Intraoperative Irrigation

  • Enrico Bellato,
  • Filippo Castoldi,
  • Lucrezia Massobrio,
  • Valentina Bartolotti,
  • Carmelo Giannone,
  • Helena Villavicencio,
  • Narcisa Mandras,
  • Alessandro Bondi,
  • Francesca Menotti and
  • Valeria Allizond
  • + 2 authors

30 July 2026

Background: Prosthetic joint infection (PJI) following total shoulder arthroplasty (TSA) is a rare but clinically relevant complication, largely attributable to the distinctive shoulder skin microbiome, predominantly composed of Cutibacterium acnes a...

  • Review
  • Open Access
43 Citations
8,000 Views
16 Pages

Effect of Endodontic Irrigating Solutions on Radicular Dentine Structure and Matrix Metalloproteinases—A Comprehensive Review

  • Abayomi Omokeji Baruwa,
  • Jorge N. R. Martins,
  • Tatjana Maravic,
  • Claudia Mazzitelli,
  • Annalisa Mazzoni and
  • António Ginjeira

23 November 2022

Irrigating solutions play an important role in the eradication of intracanal microbes and debris dissolution during endodontic treatment. Different combinations of solutions and protocols have been advocated, with sodium hypochlorite (NaOCl), ethylen...

(This article belongs to the Special Issue Endodontics and Restorative Sciences)
  • Article
  • Open Access
2 Citations
4,610 Views
14 Pages

Evaluation of pH and Optical Properties of Dual Rinse HEDP Irrigating Solution

  • Andjelka Simic,
  • Mirjana V. Papic,
  • Ana Nikitovic,
  • Aleksandar Kocovic,
  • Renata Petrovic,
  • Irena Melih,
  • Suzana Zivanovic,
  • Milos Papic and
  • Milica Popovic

19 February 2024

This study investigates the pH values and optical characteristics of Dual Rinse HEDP, either independently or combined with sodium hypochlorite (NaOCl), and compares them to other irrigants used in endodontics. The solutions used in this study were c...

(This article belongs to the Section Applied Dentistry and Oral Sciences)
  • Systematic Review
  • Open Access
16 Citations
7,436 Views
25 Pages

Effect of Different Irrigating Solutions on Root Canal Dentin Microhardness—A Systematic Review with Meta-Analysis

  • Sunidhi Agarwal,
  • Lora Mishra,
  • Naomi Ranjan Singh,
  • Rini Behera,
  • Manoj Kumar,
  • Ravishankar Nagaraja,
  • Krzysztof Sokolowski and
  • Barbara Lapinska

The aim of this study was to evaluate the effect of different irrigating solutions as well as their combination and activation modes on root canal dentin microhardness. The protocol was registered in PROSPERO and PRISMA guidelines were followed. The...

(This article belongs to the Special Issue Biomaterials in Restorative Dentistry and Endodontics)
  • Article
  • Open Access
1 Citations
1,095 Views
17 Pages

CLSM-Guided Imaging to Visualize the Depth of Effective Disinfection in Endodontics

  • Rebecca Mattern,
  • Sarah Böcher,
  • Gerhard Müller-Newen,
  • Georg Conrads,
  • Johannes-Simon Wenzler and
  • Andreas Braun

1 December 2025

Background/Objectives: Important goals of endodontic treatment procedures are to effectively eliminate microorganisms from the root canal system and prevent reinfection. Despite advances in techniques, these goals continue to be difficult to achieve...

(This article belongs to the Special Issue Antibacterial Treatment in Periodontal and Endodontic Therapy, 3rd Edition)
  • Article
  • Open Access
9 Citations
3,504 Views
11 Pages

10 April 2025

Objectives: This study aims to evaluate the effectiveness of current conventional and advanced irrigation techniques after minimally invasive instrumentation in necrotic oval root canals by histological analysis. Methods: Seventy extracted necrotic l...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
5 Citations
4,780 Views
13 Pages

12 December 2023

This study aimed to assess the amount of erosion during activated endodontic irrigation with either HEDP or EDTA via high-resolution micro-computed tomography. Two root canals of twenty premolars were prepared with ProTaper Next and irrigated with so...

  • Review
  • Open Access
5 Citations
5,697 Views
15 Pages

Irrigation in Endodontics: Polyhexanide Is a Promising Antibacterial Polymer in Root Canal Treatment

  • Zurab Khabadze,
  • Yulia Generalova,
  • Alena Kulikova,
  • Irina Podoprigora,
  • Saida Abdulkerimova,
  • Yusup Bakaev,
  • Mariya Makeeva,
  • Marina Dashtieva,
  • Mariya Balashova and
  • Yakup Rakhmanov
  • + 6 authors

1 March 2023

Background:chronic apical periodontitis is a common pathology in dentistry, especially in endodontics. It is necessary to systematize data concerning commonly used irrigation solutions. The development of new protocols for endodontic treatment is a v...

(This article belongs to the Special Issue Endodontics and Restorative Sciences)
  • Article
  • Open Access
1 Citations
1,963 Views
18 Pages

Brassica chinensis L. is often grown using ‘excessive water and fertilizer’, which has a negative impact on the inter-root soil environment and the yield and quality of the plant. As the concept of green and sustainable development takes...

(This article belongs to the Special Issue Irrigation and Water Management Strategies for Horticultural Systems)
  • Article
  • Open Access
3 Citations
4,429 Views
10 Pages

In this in vitro study, we aimed to evaluate and compare the antibacterial efficacy of a novel erbium-doped yttrium aluminum garnet laser modality, shock wave enhanced emission of photoacoustic streaming (SWEEPS), ultrasonically activated irrigation...

(This article belongs to the Section Regenerative Engineering)
  • Article
  • Open Access
17 Citations
5,397 Views
25 Pages

Development of Smart Irrigation Equipment for Soilless Crops Based on the Current Most Representative Water-Demand Sensors

  • Francisco Sánchez Millán,
  • Francisco J. Ortiz,
  • Teresa C. Mestre Ortuño,
  • Antonio Frutos and
  • Vicente Martínez

16 March 2023

Due to the edaphoclimatic conditions in southeast Spain, which are expected to worsen due to climate change, more efficient ways of using water must be found to maintain sustainable agriculture. Due to the current high price of irrigation control sys...

(This article belongs to the Section Smart Agriculture)
  • Article
  • Open Access
14 Citations
4,726 Views
13 Pages

Isolation of Endogenous TGF-β1 from Root Canals for Pulp Tissue Engineering: A Translational Study

  • Matthias Widbiller,
  • Andreas Rosendahl,
  • Melanie Wölflick,
  • Moritz Linnebank,
  • Benedikt Welzenbach,
  • Karl-Anton Hiller,
  • Wolfgang Buchalla and
  • Kerstin M. Galler

30 January 2022

Cell homing for dental pulp tissue engineering has been advocated as a feasible approach to regenerate dental pulp in a clinical setting. In order to develop a translational protocol for clinical application, we wanted to determine the effects of dis...

  • Article
  • Open Access
11 Citations
3,160 Views
15 Pages

In Situ Zymography Analysis of Matrix Metalloproteinases Activity Following Endodontic Irrigation Protocols and Correlation to Root Dentine Bond Strength

  • Abayomi Omokeji Baruwa,
  • Claudia Mazzitelli,
  • Tatjana Maravic,
  • Jorge N. R. Martins,
  • Annalisa Mazzoni and
  • António Ginjeira

30 August 2022

The objective was to evaluate the effect of different root canal irrigating solutions on the activity of matrix metalloproteinases (MMPs), and correlation to the push-out bond strength (PBS) and nanoleakage expression (NL) in the root dentin. Seventy...

(This article belongs to the Special Issue Polymers Strategies in Dental Therapy)
  • Systematic Review
  • Open Access
64 Citations
16,354 Views
25 Pages

IoT Sensing for Advanced Irrigation Management: A Systematic Review of Trends, Challenges, and Future Prospects

  • Ahmed A. Abdelmoneim,
  • Hilda N. Kimaita,
  • Christa M. Al Kalaany,
  • Bilal Derardja,
  • Giovanna Dragonetti and
  • Roula Khadra

4 April 2025

Efficient water management is crucial for sustainable agriculture, and the integration of Internet of Things (IoT) technologies in irrigation systems offers innovative solutions to optimize resource use. In this systematic review, the current landsca...

(This article belongs to the Special Issue Advancements and Challenges in IoT Communication Technologies for a Connected World)
  • Article
  • Open Access
23 Citations
5,316 Views
8 Pages

Antibiofilm Activity of Three Different Irrigation Techniques: An in Vitro Study

  • Caterina Eneide,
  • Raffaella Castagnola,
  • Cecilia Martini,
  • Nicola Maria Grande,
  • Francesca Bugli,
  • Romeo Patini,
  • Massimo Cordaro,
  • Maurizio Sanguinetti,
  • Giovanni Olivi and
  • Luca Marigo
  • + 1 author

The microbial infection of the endodontic space occurs in a necrotic tooth as a result of dental caries, trauma, periodontal disease, or previous root canal therapy. The disruption of the biofilms and the reduction of the bacterial load inside root c...

(This article belongs to the Special Issue Antibiotics and Antimicrobials in Dentistry)
  • Article
  • Open Access
15 Citations
5,014 Views
19 Pages

Control of Substrate Water Availability Using Soil Sensors and Effects of Water Deficit on the Morphology and Physiology of Potted Hebe andersonii

  • Daniel Bañón,
  • Beatriz Lorente,
  • Sebastián Bañón,
  • María Fernanda Ortuño,
  • María Jesús Sánchez-Blanco and
  • Juan José Alarcón

15 January 2022

Many plant producers tend to overwater crops to prevent water stress and salt-induced damage. These practices waste irrigation water and cause leaching that harms the environment and increases production costs. In order to optimize water consumption...

(This article belongs to the Special Issue Advances in Plant Physiology of Abiotic Stresses)
  • Article
  • Open Access
56 Citations
4,996 Views
13 Pages

The Potential of the Synthetic Strigolactone Analogue GR24 for the Maintenance of Photosynthesis and Yield in Winter Wheat under Drought: Investigations on the Mechanisms of Action and Delivery Modes

  • Mojde Sedaghat,
  • Yahya Emam,
  • Ali Mokhtassi-Bidgoli,
  • Saeid Hazrati,
  • Claudio Lovisolo,
  • Ivan Visentin,
  • Francesca Cardinale and
  • Zeinolabedin Tahmasebi-Sarvestani

16 June 2021

Strigolactones (SLs) have been implicated in many plant biological and physiological processes, including the responses to abiotic stresses such as drought, in concert with other phytohormones. While it is now clear that exogenous SLs may help plants...

  • Article
  • Open Access
8 Citations
3,892 Views
11 Pages

Effectiveness of the REvision System and Sonic Irrigation in the Removal of Root Canal Filling Material from Oval Canals: An In Vitro Study

  • Marc Krikor Kaloustian,
  • Claire El Hachem,
  • Carla Zogheib,
  • Walid Nehme,
  • Louis Hardan,
  • Pamela Rached,
  • Naji Kharouf,
  • Youssef Haikel and
  • Davide Mancino

This study aimed to evaluate the effectiveness of the Endostar REvision system (Poldent, Warsaw, Poland) in the removal of filling materials from oval root canals using sonic irrigation as an additional cleaning method. Thirty human-extracted mandibu...

(This article belongs to the Special Issue Recent Advances in Biomaterials and Dental Disease)
  • Article
  • Open Access
4 Citations
3,857 Views
9 Pages

Endodontic Irrigants and Their Activation Efficacy on Cleansing Post-Space Root Canal Walls

  • Manuela Marchese,
  • Pontoriero I. K. Denise,
  • Edoardo Ferrari Cagidiaco,
  • Alfredo Iandolo,
  • Simone Grandini and
  • Marco Ferrari

1 December 2021

The aim of this study was to evaluate the efficacy of activated irrigants (EDTA e NaOCL) during the cleansing of root walls, of the smear layer, of the debris, and gutta-percha after the preparation of the restorative space. Twenty single and multi-r...

  • Review
  • Open Access
2,930 Views
14 Pages

Prevention and Treatment of Surgical Site Infections in Orthopaedic Surgery: An Italian Delphi Consensus on Risk Stratification and Wound Irrigation Strategies

  • Pier Francesco Indelli,
  • Massimiliano De Paolis,
  • Arcangelo Russo,
  • Massimo Fantoni,
  • Augusto Palermo,
  • Giovanni Pomponio,
  • Alessandro Scalise,
  • Domenico Tigani,
  • Bruno Violante and
  • Pierluigi Viale
  • + 2 authors

24 February 2026

Introduction: Surgical site infections (SSIs) and prosthetic joint infections remain among the most serious complications in orthopedic surgery, and chemical debridement is recommended for all septic revisions. The combination of polyhexanide (PHMB)...

(This article belongs to the Special Issue Clinical Advances in Trauma and Orthopaedic Surgery)
  • Protocol
  • Open Access
11 Citations
10,385 Views
12 Pages

Background: Essential oils have gained in significance due to their various biological activities, and there is a growing demand for them in many industries. The present article focuses on the technical steps for an in vitro evaluation of the antibac...

(This article belongs to the Section Biochemical and Chemical Analysis & Synthesis)
  • Feature Paper
  • Article
  • Open Access
4 Citations
1,111 Views
19 Pages

Patterns of Endodontic Practice and Technological Uptake Across Training Levels in Spain and Latin America: Results from a Multicountry Survey of 1358 Clinicians

  • Rocío Piñas-Alonzo,
  • Alejandro R. Pérez,
  • José Aranguren,
  • Gaya C. S. Vieira,
  • Juan Carlos Paz,
  • Juan Saavedra,
  • Jenny Guerrero Ferreccio,
  • Simone Grandini and
  • Giulia Malvicini

27 November 2025

Background/Objectives: The objective of this study was to investigate current endodontic practice patterns and the adoption of newer technologies among dentists, endodontic specialists, and postgraduate students in Spain and Latin America. Methods: A...

(This article belongs to the Special Issue Endodontics and Restorative Sciences: 2nd Edition)
  • Review
  • Open Access
1 Citations
1,072 Views
24 Pages

19 June 2026

Background: The objective was to synthesize and critically appraise systematic reviews with meta-analysis evaluating the association between irrigation, instrumentation, and obturation procedures and post-operative endodontic pain. Methods: An umbrel...

(This article belongs to the Special Issue Root Canal Treatment and Healing Outcomes: Clinical Application of Endodontic Biomaterials and Postoperative Management)
  • Article
  • Open Access
646 Views
13 Pages

9 March 2026

Background and objectives: Head and neck cancer patients frequently undergo radiotherapy, which can affect the properties of dental hard tissues. This study aimed to evaluate the effects of root canal treatment, radiotherapy, and sonic activation dur...

(This article belongs to the Special Issue Endodontic Disease: Prevalence, Risk Factors, and Treatment Outcome)
  • Article
  • Open Access
26 Citations
4,936 Views
8 Pages

Smear Layer and Debris Removal from Root Canals Comparing Traditional Syringe Irrigation and 3D Cleaning: An Ex Vivo Study

  • Alfredo Iandolo,
  • Massimo Pisano,
  • Dina Abdellatif,
  • Giuseppe Sangiovanni,
  • Giuseppe Pantaleo,
  • Stefano Martina and
  • Alessandra Amato

6 January 2023

Background: Endodontic treatment objectives comprise eliminating or decreasing bacterial load inside the complex endodontic space. Removing the smear layer and debris becomes mandatory to achieve good three-dimensional (3D) cleaning. Aim: This study...

(This article belongs to the Section Clinical Guidelines)
  • Article
  • Open Access
1 Citations
1,056 Views
18 Pages

Background: Successful healing of chronic apical periodontitis after endodontic treatment requires a reduction in the size of the radiolucent area and the healing of the bone. This study aimed to compare the effects of different irrigation activation...

(This article belongs to the Section Clinical Diagnosis and Prognosis)

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