Submit to Applied Sciences Review for Applied Sciences Propose a Special Issue

Journal Menu

Journal Browser

Research on Endodontic Treatment Methods and Materials

Print Special Issue Flyer
Special Issue Editors
Special Issue Information
Keywords
Benefits of Publishing in a Special Issue
Related Special Issue
Published Papers

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Dentistry and Oral Sciences".

Deadline for manuscript submissions: closed (20 March 2025) | Viewed by 16803

Share This Special Issue

Special Issue Editors

Dr. Márk Antal

E-Mail Website
Guest Editor

Department of Esthetic and Operative Dentistry, Faculty of Dentistry, University of Szeged, 6720 Szeged, Hungary
Interests: endodontic microsurgery
Special Issues, Collections and Topics in MDPI journals

Dr. Márk Fráter

E-Mail Website
Guest Editor

Department of Esthetic and Operative Dentistry, Faculty of Dentistry, University of Szeged, 6720 Szeged, Hungary
Interests: resin composite; fiber-reinforced composite; root canal-treated teeth; fracture resistance; direct restoration; adhesive restoration
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The first two decades of the 21st century have seen spectacular developments in the dental sciences and related technologies, which have also transformed the way we think of endodontics. What was once not much more than root canal treatment is now an entire complex subdiscipline of dentistry equipped with an armamentarium of the latest technologies, including surgical microscopes, high-resolution digital imaging and computer-assisted guided surgery tailored to the individual patient’s needs. This development offers the practitioner an ever-growing set of tools to save patients’ teeth with ever-growing success rates.

This Special Issue aims to provide an overview of the latest research in endodontics and endodontic surgery, from bench science to chairside and clinical studies. The Special Issue features studies that can further our understanding of the latest issues and developments in the field and help the readers familiarize themselves with the state of the art in endodontics.

Topics of potential interest include (the list is not exhaustive):

Static and dynamic navigation in endodontic surgery;
The role and accuracy of digital (CBCT) imaging in endodontics;
The advantages and limitations of new technologies;
Success and survival in endodontics;
Materials and material-related issues;
Preclinical research regarding emerging endodontic techniques.

Dr. Márk Antal
Dr. Márk Fráter
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

endodontics
endodontic surgery
static guidance
dynamic guidance
endodontic anatomy
periapical anatomy
precision of endodontic interventions
success of endodontic interventions

Benefits of Publishing in a Special Issue

Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Related Special Issue

Research on Endodontic Treatment Methods and Materials—2nd Edition in Applied Sciences

Published Papers (9 papers)

Download All Papers

Order results

Result details

Show export options Show export options

Select all

Export citation of selected articles as:

Research

Jump to: Other

12 pages, 213 KiB

Open AccessArticle

Six-Month Treatment Outcomes of Vital Pulp Therapy in Adults Using Biomaterials: A Prospective Cohort Pilot Study

by Melinda Polyák, Eszter Ágnes Szalai, Péter Komora and János Vág

Appl. Sci. 2025, 15(8), 4276; https://doi.org/10.3390/app15084276 - 12 Apr 2025

Viewed by 279

Abstract

Vital pulp therapy (VPT) preserves dental pulp and its functions, offering a minimally invasive alternative to root canal therapy. However, the impact of patient-related factors on success remains unclear. This study aimed to estimate the sample size for a multivariate model predicting VPT success for assessing capping material, age, sex, and pulp conditions. A prospective cohort study was conducted with the inclusion of twenty-seven adult patients with carious pulp exposure in mature permanent teeth. Treatment comprised direct pulp capping, partial pulpotomy, or complete pulpotomy with Mineral Trioxide Aggregate Plus (MTA+) or Biodentine. Success rates were evaluated at 6 months through clinical and radiographic examinations. Statistical analysis included Pearson’s Chi-square tests and logistic regression. The success rates were 64% in the Biodentine group and 92% in the MTA+ group (OR: 0.15; p = 0.108). Sex and age had no significant effect. Success declined with increasing pulp condition severity and treatment invasiveness. MTA+ had a higher incidence of discoloration, while Biodentine showed none. Sample size calculations suggested 140 participants would be needed to detect a significant effect of pulp condition. Both materials were effective, though MTA+ showed higher success based on the strict success criteria. More severe pulpitis correlated with lower success, but a larger study is needed for predictive models. Full article

(This article belongs to the Special Issue Research on Endodontic Treatment Methods and Materials)

14 pages, 1849 KiB

Open AccessArticle

In Vitro Evaluation of Root Surface Temperature Using Different Endodontic Filling Techniques

by Lea Külzer, Theresia Saban, Andreas Braun and Johannes-S. Wenzler

Appl. Sci. 2024, 14(21), 9830; https://doi.org/10.3390/app14219830 - 28 Oct 2024

Viewed by 3192

Abstract

Depending on the obturation technique, the tooth and surrounding tissues may heat up during root canal filling, particularly with warm methods. This study aimed to analyze the temperature increase in the periradicular and -apical region during various warm obturation techniques with a present simulated periodontal blood flow. Seventy-five extracted human teeth were shortened to 11 mm (cut-grinder Primus diamond cutting device; Walter Messner GmbH, Oststeinbek, Germany) and prepared using the ProTaper Gold system (Dentsply Sirona Inc., Charlotte, NC, USA) ISO size 40/.06. Specimens were prepared to ensure stable fluid circulation in an artificially created periodontal space, and the procedure was recorded with a thermal infrared camera (VarioCAM HD; InfraTec GmbH Infrarotsensorik und Messtechnik, Dresden, Germany). The following obturation methods were applied: I, cold single-cone obturation (control group); II, gutta-percha-coated rigid carrier technique (GuttaFusion); III, squirting technique (injection technique); IV, continuous wave technique; and V, Schilder technique. Statistical analysis was performed using the Kruskal–Wallis test, followed by the Mann–Whitney pairwise test using the sequential Bonferroni procedure for significant differences (p < 0.05). The Schilder technique with 0 mL/min showed the lowest temperature change, with a median of 0.00 °C (max. 0.00 °C, min. 0.00 °C, IQR 0.00 °C). In contrast, the continuous wave technique at a circulation rate of 2.6 mL/min exhibited the highest temperature change, with a median of 3.76 °C (max. 5.33 °C, min. 2.42 °C, IQR 1.46 °C). Although warm obturation techniques can increase surface temperature, none of the methods produced changes that were potentially damaging to the periodontium or surrounding bone. Full article

(This article belongs to the Special Issue Research on Endodontic Treatment Methods and Materials)

► Show Figures

Figure 1

15 pages, 4985 KiB

Open AccessArticle

Retreatability of Bioceramic-Filled Teeth: Comparative Analysis of Single-Cone and Carrier-Based Obturation Using a Reciprocating Technique

by Andrea Spinelli, Fausto Zamparini, Jacopo Lenzi, Davide Carboni, Maria Giovanna Gandolfi and Carlo Prati

Appl. Sci. 2024, 14(15), 6444; https://doi.org/10.3390/app14156444 - 24 Jul 2024

Cited by 1 | Viewed by 1497

Abstract

Objectives: To evaluate the retreatment efficacy of premixed bioceramic sealer using a reciprocating system, comparing single-cone and carrier-based obturation techniques. Materials and Methods: Twenty-three monoradicular teeth with oval canals were divided into two groups: NeoSealer Flo with single cone (SC) and NeoSealer Flo with Guttafusion (GF). Retreatment was performed using Reciproc Blue (RB) with a crown-down technique. X-ray and CBCT images were taken to measure the remnant areas and volumes. Results: Apical patency was achieved in all the samples. The remnants were mostly distributed in the middle third in the GF group, while an equal distribution in both the middle and apical thirds was observed in the SC group. The GF group had a lower remnant area and volume after RB 50.05, respectively (0.18 ± 0.33 mm² vs. 0.39 ± 0.80 mm² and 0.36 ± 0.59 mm³ vs. 0.51 ± 1.16 mm³). The use of RB 50.05 led to an additional reduction in the remnant areas in the SC (14.89%) and GF (69.49%) groups, while in terms of the volume, the reductions were 20.63% and 36.36%. Conclusions: Reciprocating instruments are effective in removing remnants from root canals filled with both single-cone and carrier-based techniques. The blooming effect in CBCT imaging suggests further in vivo studies for validation. Full article

(This article belongs to the Special Issue Research on Endodontic Treatment Methods and Materials)

► Show Figures

Figure 1

12 pages, 1842 KiB

Open AccessArticle

Efficacy of Different Irrigation Activation Techniques on Dentinal Tubule Penetration of the Novel AH-Plus Bioceramic Sealer

by Alhasan Almasri, Mohamad Abduljalil and Umut Aksoy

Appl. Sci. 2024, 14(2), 701; https://doi.org/10.3390/app14020701 - 14 Jan 2024

Cited by 1 | Viewed by 2440

Abstract

This study aimed to assess the penetration of AH-Plus (AHP) and AH-Plus Bioceramic (AHPB) sealers into dentinal tubules subsequent to different irrigation activation protocols. One hundred fifty teeth were divided into five groups according to the final irrigation protocol: conventional syringe irrigation (CSI), EndoActivator (EA), passive ultrasonic irrigation (PUI), Er,Cr:YSGG laser, and SWEEPS. Then, the teeth were divided into two subgroups (n = 15) according to the canal sealer type. The maximum penetration depth (MPD) point and percentage of the sealer were evaluated using confocal laser scanning microscopy. Then, the data were statistically analyzed. The highest MPD values were observed in the SWEEPS groups, while the lowest value was in the CSI groups. Considering the effect of the sealer type and irrigation protocol interaction, there was a significant difference between the Er,Cr:YSGG laser, and EA groups for the AHPB sealer (p < 0.05), while it was insignificant for the AHP sealer (p > 0.05). The AHP and AHPB sealers statistically presented similar penetration properties. Laser-activated irrigation presented a higher sealer penetration compared to the other techniques. Full article

(This article belongs to the Special Issue Research on Endodontic Treatment Methods and Materials)

► Show Figures

Figure 1

11 pages, 1054 KiB

Open AccessArticle

Comparative Study of the Expansive Behaviour of Different Internal Bleaching Agents

by Alba Pallarés-Serrano, Sandra Pallarés-Serrano, Antonio Pallarés-Serrano, Guillermo Martinez-Martinez and Antonio Pallarés-Sabater

Appl. Sci. 2024, 14(2), 532; https://doi.org/10.3390/app14020532 - 8 Jan 2024

Viewed by 1628

Abstract

Internal bleaching is a conservative treatment applied to a darkened endodontically treated tooth to restore its original colour, either as a single treatment or as a treatment prior to a subsequent prosthetic phase. The aim of this study was to objectively measure and compare using an experimental model the expansive capacity of four bleaching groups: carbamide peroxide 37% (CP 37%), hydrogen peroxide 30% (HP 30%), HP 30% mixed with sodium perborate (SP) and SP mixed with distilled water. A total of 150 lower incisors (n = 30 in each group) were prepared for the Walking Bleach technique and a glass tube with oil was introduced into the coronal access cavity to measure the expansive capacity through oil displacement, due to the reaction that occurs when bleaching agents interact with dental tissues. The results after 10 days were analysed with the Games–Howell post hoc test to compare the samples. Significant higher expansion was observed with HP 30% (p < 0.05) and lower expansion with SP (p < 0.05) compared to the other groups. No significant differences were observed between CP 37% (p > 0.05) and HP 30% + SP (p > 0.05). This provides significant and observable information on the behaviour of each bleaching group and its evolution after 10 days. Full article

(This article belongs to the Special Issue Research on Endodontic Treatment Methods and Materials)

► Show Figures

Figure 1

10 pages, 1316 KiB

Open AccessArticle

Effect of Intermediate Irrigation on Temperature Rise during Broken NiTi File Removal Using Ultrasonic Device

by László Pintér, Károly Krajczár, Fanni Őry, József Szalma and Edina Lempel

Appl. Sci. 2023, 13(17), 9761; https://doi.org/10.3390/app13179761 - 29 Aug 2023

Cited by 2 | Viewed by 1998

Abstract

Endodontic preparation with ultrasonic instruments can lead to temperature rise (TR) on the external root surface (ERF), which may damage the periodontium. The aim was to measure the TR due to the ultrasonic preparation applied at different energy levels and durations during the removal of broken endodontic instrument from the root canal. Thirty-five maxillary central incisors were decoronated and 4 mm of NiTi instruments were fractured 5 mm from the most coronal part of the root. The roots were divided into seven groups according to the preparation mode (endodontic-E5, periodontal-P3) and preparation duration (30 s, 45 s, 60 s). Ultrasonic preparation was performed in periods consisting of four preparation phases with intermediate irrigations and drying. During all preparations, the TR was recorded on ERF using a K-type thermocouple. The results demonstrated that the TR measured at the end of the preparation period was higher than at baseline in all groups (p < 0.001). The largest TR (8.0 ± 0.5 °C) occurred at high energy level (P3) with 60 s preparation duration (p < 0.001). The TR measured after rinsing was significantly lower than before rinsing (p < 0.001). In conclusion, rinsing between ultrasonic preparation phases can reduce the TR, which might be potentially harmful using high-energy exceeding 60 s. Full article

(This article belongs to the Special Issue Research on Endodontic Treatment Methods and Materials)

► Show Figures

Figure 1

11 pages, 4716 KiB

Open AccessArticle

Comparison of the Three-Dimensional Accuracy of Guided Apicoectomy Performed with a Drill or a Trephine: An In Vitro Study

by Ramóna Kiscsatári, Eszter Nagy, Máté Szabó, Gábor Braunitzer, József Piffkó, Márk Fráter and Márk Ádám Antal

Appl. Sci. 2023, 13(17), 9642; https://doi.org/10.3390/app13179642 - 25 Aug 2023

Cited by 1 | Viewed by 1597

Abstract

Guided apicoectomy performed with 3D-printed polymer-based static surgical guides is an emerging trend in endodontic surgery. Static-guided apicoectomy is carried out with either a drill or a trephine. The aim of this in vitro study was to assess the accuracy of osteotomy and apicoectomy performed through a polymer guide, with both drill and trephine, and to compare the accuracy achievable with the two instruments. Six plaster models of a maxilla master model with extracted human maxillary teeth in polymethyl-methacrylate resin were used. The modeled osteotomies were performed in these. The master model was CBCT-scanned, and digital surgical plans were prepared, based on which the surgical guides were printed. The plans contained both drill and trephine apicoectomies. Digital three-dimensional position analysis was performed with dedicated algorithms. A total of 39 drill and 47 trephine osteotomies were analyzed. A statistically significant difference between the two instruments was found only in the global deviation of the distal endpoint, indicating lower deviation for the trephine procedure (1.53 mm vs. 1.31 mm, p = 0.038). Nevertheless, from a clinical perspective, this distinction is inconsequential. The results suggest that, for all practical purposes, the two approaches to apicoectomy allow the same level of accuracy. Full article

(This article belongs to the Special Issue Research on Endodontic Treatment Methods and Materials)

► Show Figures

Figure 1

11 pages, 5185 KiB

Open AccessArticle

An Exploratory In Vitro Microcomputed Tomographic Investigation of the Efficacy of Semicircular Apicoectomy Performed with Trephine Bur

by Eszter Nagy, Brigitta Vőneki, Lívia Vásárhelyi, Imre Szenti, Márk Fráter, Ákos Kukovecz and Márk Ádám Antal

Appl. Sci. 2023, 13(16), 9431; https://doi.org/10.3390/app13169431 - 20 Aug 2023

Viewed by 1450

Abstract

Purpose: Recently, a novel approach to apicoectomy has emerged, involving the use of a hollow trephine with a surgical guide. This innovative technique creates a semicircular section, in contrast to the conventional straight cut (with a bur). The semicircular shape of this section raises questions about the method’s effectiveness in eliminating supernumerary canals (SNCs), which are auxiliary canals alongside the main root canal. These canals pose a risk of further infection if not thoroughly eliminated. The aim of this exploratory study was to assess the efficacy of the proposed method in the removal of SNCs. Methods: A sample of 200 extracted single-rooted human teeth was rigorously narrowed down by multiple steps to 33 specimens that contained SNCs in the apical third. These specimens underwent apical semicircular sectioning, removing the apical 3 mm of the root. The specimens then underwent repeated CT scanning. For samples with residual SNCs, the section was transformed into a straight section and another CT scan was performed. Results: The semicircular section eliminated all SNCs in 94% of the specimens, and it eliminated 97.3% of the SNCs in all specimens. The straight-line sectioning eliminated 98.6% of all SNCs and eliminated all SNCs in 96.97% of the SNC-containing teeth. Conclusions: The efficacy of semicircular apicoectomy performed with a trephine appears to be comparable (χ² = 1.00, df = 1, and p = 0.317) to that of the conventional straight apicoectomy performed with a bur as reported in the literature. Full article

(This article belongs to the Special Issue Research on Endodontic Treatment Methods and Materials)

► Show Figures

Figure 1

Other

Jump to: Research

8 pages, 1596 KiB

Open AccessCase Report

Idiopathic External Cervical Resorption of the Impacted Second Premolar: A Case Report

by Eglė Zasčiurinskienė, Liveta Rastokaitė, Pedram Hosseinzadehfard and Greta Lodienė

Appl. Sci. 2023, 13(20), 11383; https://doi.org/10.3390/app132011383 - 17 Oct 2023

Cited by 1 | Viewed by 1577

Abstract

The tooth impaction of the lower second premolars is an occasional condition but is still seen in clinical practice with a prevalence of 0.6–2.6%. The present case report describes a rare condition of the lower second premolar impaction. An 11-year-old female patient presented with the anteroposterior dental discrepancy, midline shift, and occlusal cant. Intraoral examination revealed the absence of the lower right second premolar with no space available for the eruption. X-ray examination revealed the impaction of tooth #45 in a vertical position, tilting of the adjacent teeth, and two-thirds root length development. The orthodontic treatment plan included space opening using a fixed appliance with a coil spring. The natural eruption of the tooth was expected according to dental age and root development. When the space was opened, no change in the position of tooth #45 was observed. Surgical exposure and active traction were performed. However, the intrusion and tilting of adjacent teeth were observed during the next appointments with no vertical change of tooth #45. Ankylosis was suspected as no tooth movement was recorded. The surgical luxation and osteotomy of the coronal alveolar bone of the impacted tooth were planned for the imminent forced eruption, which was expected due to the young age of the patient. Consequently, the crown of tooth #45 emerged and the bracket was placed. Further traction was planned to use a micro-screw. Following the traction, no vertical displacement of the tooth was observed in the subsequent appointments. Radiographic examination revealed radiolucency in the coronal third of the root. The patient was referred to the endodontist, and CBCT revealed external cervical root resorption in the late reparative stage. ECR in an impacted tooth, mimicking the manifestation of tooth ankylosis, can cause orthodontic treatment failure. Full article

(This article belongs to the Special Issue Research on Endodontic Treatment Methods and Materials)

► Show Figures

Journal Menu

Journal Browser

Research on Endodontic Treatment Methods and Materials

Share This Special Issue

Special Issue Editors

Special Issue Information

Keywords

Benefits of Publishing in a Special Issue

Related Special Issue

Published Papers (9 papers)

Research

Other

Further Information

Guidelines

MDPI Initiatives

Follow MDPI