Endodontic Disease: Prevalence, Risk Factors, and Treatment Outcome
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 222
Special Issue Editors
Interests: dentistry; devitalised teeth reconstruction; dental materials; color measurement; optical tech-niques; biomaterials; tissue engineering
Interests: endodontics; periapical lesions; irrigation solutions; root canal treatment; color science; ceramic restorations
Interests: endodontics; bioceramic; rotary instrumentation; periapical lesions; coronal restoration
Special Issue Information
Dear Colleagues,
This Special Issue of JCM explores endodontic disease, focusing on its prevalence, risk factors, and treatment outcomes—topics of increasing importance in everyday dental practice. As the global burden of pulpal and periapical pathologies grows, a deeper understanding of their etiology and clinical management is essential for both general dentists and endodontists. The content of this Special Issue will explore the epidemiology of endodontic disease, highlighting systemic and local risk factors such as caries, trauma, periodontal conditions, and restorative complications. Emphasis will be placed on diagnostic severity and treatment complexity, and how these factors influence prognosis and treatment planning. Clinical outcomes are shaped by a range of elements such as microbial resistance, root canal anatomy, the precision of the procedure, and individual patient characteristics. Although research and clinical techniques have advanced significantly, gaps remain in standardizing diagnostic criteria, outcome measures, and long-term follow-up data. Through original research and literature reviews, this collection of articles seeks to address these challenges and support informed clinical decision-making. Importantly, this Special Issue also connects contemporary endodontic practice with emerging technologies, such as 3D imaging, bioceramics, new irrigation and activation solutions, and techniques and regenerative approaches, highlighting their role in enhancing precision, outcomes, and the overall quality of dental care.
Prof. Dr. Razvan Ionut Ghinea
Dr. Ioana-Sofia Pop-Ciutrilă
Guest Editors
Dr. Luminita-Maria Nica
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- endodontics
- apical periodontitis
- pulpitis
- root canal treatment
- risk factors
- treatment outcomes
- regenerative endodontics
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