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Recent Developments in Endodontics and Dental Materials

A special issue of Applied Sciences (ISSN 2076-3417).

Deadline for manuscript submissions: 20 August 2025 | Viewed by 595

Special Issue Editors


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Guest Editor
Department of Restorative Dentistry, Endodontics Division, Institute of Science and Technology, São Paulo State University (ICT-UNESP), São José dos Campos 12245-000, Brazil
Interests: phytotherapy; herbal medicine; intracanal medication; endodontic irrigant; microorganisms; dental materials
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (ICT-UNESP), São José dos Campos 12245-000, Brazil
Interests: phytotherapy; herbal medicine; antimicrobial agents; anti-inflammatory agents; multidrug resistance; cell cultures; genotoxicity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Endodontic materials and techniques are in constant development. This Special Issue, titled “Recent Developments in Endodontics and Dental Materials”, aims to provide a platform for the dissemination of cutting-edge research and innovations in the field of endodontics and dental materials. The focus is on exploring advancements that enhance clinical outcomes, improve treatment efficacy, and address challenges in root canal treatment.

This Special Issue invites authors to contribute original research articles, and reviews (systematic, or non-systematic) that explore advances in root canal instrumentation techniques and technologies, innovations in obturation materials and methods, the impact of foraminal shape and morphology on treatment success, the prevention and management of apical foramen transportation, novel biomaterials for endodontic and restorative applications, clinical outcomes of minimally invasive endodontics, the role of imaging and diagnostic technologies in modern endodontics, the biocompatibility and performance of dental materials, regenerative endodontics and pulp–dentin complex restoration, and long-term success factors in endodontic treatments.

I look forward to receiving your contributions.

Dr. Amjad Abu Hasna
Dr. Luciane Dias De Oliveira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • root canal instrumentation
  • biocompatibility
  • clinical endodontics
  • endodontic irrigants
  • intracanal medication
  • bioceramics
  • foramen transportation
  • foraminal morphology
  • obturating materials
  • biomaterials in endodontics
  • minimally invasive endodontics
  • regenerative endodontics
  • dental imaging

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Published Papers (1 paper)

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Research

12 pages, 1306 KiB  
Article
Anti-Planktonic, Antibiofilm, and Synergistic Effects of Nasturtium officinale and Psidium guajava Hydroethanolic Extracts Against Standard and Clinical Strains of Enterococcus faecalis
by Lara Steffany de Carvalho, Livia Ramos Dorta da Silva, Cláudio Antonio Talge Carvalho, Maria Cristina Marcucci, Luciane Dias de Oliveira and Amjad Abu Hasna
Appl. Sci. 2025, 15(6), 3178; https://doi.org/10.3390/app15063178 - 14 Mar 2025
Viewed by 387
Abstract
Enterococcus faecalis is strongly associated with secondary/persistent root canal infections, being the most prevalent bacterium in cases of apical periodontitis in previously treated teeth. This study was elaborated to evaluate the anti-planktonic, antibiofilm, and synergistic effects of Nasturtium officinale and Psidium guajava hydroethanolic [...] Read more.
Enterococcus faecalis is strongly associated with secondary/persistent root canal infections, being the most prevalent bacterium in cases of apical periodontitis in previously treated teeth. This study was elaborated to evaluate the anti-planktonic, antibiofilm, and synergistic effects of Nasturtium officinale and Psidium guajava hydroethanolic extracts against standard and clinical strains of E. faecalis. Firstly, the N. officinale extract was prepared from watercress leaves, and P. guajava extract was prepared from guava tree leaf shoots. Then, the content of soluble solids was quantified in both. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of the isolated N. officinale and P. guajava extracts for each bacterial strain were determined using the broth microdilution method, following the Clinical and Laboratory Standards Institute (CLSI) guideline M7-A9. The MTT assay was used to evaluate the antibiofilm activity, and the fractional bactericidal concentration index (FBCI) was utilized to evaluate the synergistic effect of the N. officinale and P. guajava extracts using the checkerboard technique. Again, the MTT assay was used to evaluate the antibiofilm activity of the combined extracts this time. The data were subjected to statistical analysis using ANOVA and Tukey’s test, with a significance level of p ≤ 0.05. It was found that the soluble solid content of N. officinale was 50 mg/mL, and of P. guajava was 33.5 mg/mL. The MBC value of N. officinale was 12.5 mg/mL, and of P. guajava was 0.52 mg/mL against all the tested strains of E. faecalis. The combined 0.1 mg/mL N. officinale + 0.1 mg/mL P. guajava, and 0.1 mg/mL N. officinale + 0.5 mg/mL P. guajava hydroethanolic extracts effectively reduced the biofilm formation of the standard and clinical strain 4 of E. faecalis. Therefore, these combined extracts may be considered as endodontic irrigants in future studies. Full article
(This article belongs to the Special Issue Recent Developments in Endodontics and Dental Materials)
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