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56 Results Found

  • Article
  • Open Access
1 Citations
2,644 Views
17 Pages

Although the development of watermarking techniques has enabled designers to tackle normal processing attacks (e.g., amplitude scaling, noise addition, re-compression), robustness against malicious attacks remains a challenge. The discordant size con...

  • Article
  • Open Access
4 Citations
3,394 Views
11 Pages

Perinatal Outcomes and Neurodevelopment 1 Year after Birth in Discordant Twins According to Chorionicity

  • Mi Ju Kim,
  • Hyun Mi Kim,
  • Hyun-Hwa Cha,
  • Haemin Kim,
  • Hyo-Shin Kim,
  • Bong Seon Lim and
  • Won Joon Seong

2 March 2023

Background and Objectives: This study aimed to compare maternal complications, perinatal outcomes, and neurodevelopment 1 year after the birth between concordant and discordant twins in monochorionic and dichorionic twins. Materials and Methods: This...

  • Article
  • Open Access
9 Citations
2,636 Views
16 Pages

8 December 2022

Purpose: Biomarker discordances and alterations can be encountered between tru-cut biopsy and residual tumor in breast cancer treated with neoadjuvant chemotherapy (NACTx). We aimed to investigate the effect of NACTx on major biomarker expression (ER...

  • Article
  • Open Access
627 Views
13 Pages

(1) Background: In the context of cardiac radiofrequency (RF) ablation, it has been proposed that positioning the dispersive patch (DP) concordantly with the orientation of the ablation electrode may enhance lesion size. The objective of this study i...

  • Article
  • Open Access
258 Views
20 Pages

18 January 2026

Background/Objectives: Gestational exposure to substances (GES) is associated with adverse developmental outcomes. Early identification is limited by reliance on self-reported data. This study assessed the incidence and predictors of discordance in G...

  • Article
  • Open Access
8 Citations
6,590 Views
18 Pages

Genetic Introgression and Morphological Variation in Naked-Back Bats (Chiroptera: Mormoopidae: Pteronotus Species) along Their Contact Zone in Central America

  • Aline Méndez-Rodríguez,
  • Javier Juste,
  • Alejandro Centeno-Cuadros,
  • Flor Rodríguez-Gómez,
  • Alejandra Serrato-Díaz,
  • Juan Luis García-Mudarra,
  • Luis Manuel Guevara-Chumacero and
  • Ricardo López-Wilchis

30 April 2021

Two sibling bare-backed bat species (Pteronotus fulvus and P. gymnonotus) have been traditionally differentiated by their size. However, intermediate specimens between the two species have been found in sympatric populations along southern Mexico and...

  • Article
  • Open Access
348 Views
16 Pages

Multidetector Computed Tomography and Aortic Stenosis: The Emerging Potential of Bridging Morphology and Severity Grading

  • Gabriele Cordoni,
  • Diana Di Paolantonio,
  • Maria Teresa Savo,
  • Dan Alexandru Cozac,
  • Eleonora Lassandro,
  • Martina Palmisano,
  • Giulia Andolina,
  • Giorgio De Conti,
  • Julien Ternacle and
  • Valeria Pergola
  • + 1 author

17 December 2025

Background/Objectives: Echocardiography is the reference standard for grading aortic stenosis (AS); however, it yields discordant severity estimates in up to 40% of patients. Multidetector computed tomography (MDCT)-derived methods for calculating ao...

  • Article
  • Open Access
3 Citations
2,136 Views
16 Pages

26 April 2024

The genus Rorippa belongs to the family Brassicaceae, and its members usually have high medicinal value. The genus consists of approximately 75 species and mainly grows in the Northern Hemisphere, occurring in every continent except Antarctica. The t...

  • Article
  • Open Access
1 Citations
1,614 Views
16 Pages

APOE Genotype, ApoE Plasma Levels, Lipid Metabolism, and Cognition in Monozygotic Twins with, at Risk of, and without Affective Disorders

  • Jon Dyg Sperling,
  • Ruth Frikke-Schmidt,
  • Thomas Scheike,
  • Lars Vedel Kessing,
  • Kamilla Miskowiak and
  • Maj Vinberg

18 April 2024

Background: Lipids influence brain function and mental health. Understanding the role of apolipoproteins in affective disorders could provide valuable insights and potentially pave the way for novel therapeutic approaches. Methods: We examined the ap...

  • Article
  • Open Access
2 Citations
4,211 Views
23 Pages

Hypothesis Test to Compare Two Paired Binomial Proportions: Assessment of 24 Methods

  • José Antonio Roldán-Nofuentes,
  • Tulsi Sagar Sheth and
  • José Fernando Vera-Vera

6 January 2024

The comparison of two paired binomial proportions is a topic of interest in statistics, with important applications in medicine. There are different methods in the statistical literature to solve this problem, and the McNemar test is the best known o...

  • Article
  • Open Access
26 Citations
8,500 Views
18 Pages

Nutrition and Rheumatoid Arthritis Onset: A Prospective Analysis Using the UK Biobank

  • Camilla Barbero Mazzucca,
  • Lorenza Scotti,
  • Giuseppe Cappellano,
  • Francesco Barone-Adesi and
  • Annalisa Chiocchetti

8 April 2022

Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the joints. The multifactorial etiopathogenesis of RA has been heavily investigated, but is still only partially understood. Diet can represent both a risk factor and a protecti...

  • Article
  • Open Access
4 Citations
2,639 Views
15 Pages

A Prospective Cross-Sectional Study on the Comparison of Ultrasound Assessment vs. Palpation in Chronic Lymphocytic Leukemia Patients in the Era of Targeted Therapy

  • Edoardo Benedetti,
  • Fabrizio Mavilia,
  • Claudia Baratè,
  • Emilia Bramanti,
  • Riccardo Morganti,
  • Giulia Cervetti,
  • Enrico Capochiani,
  • Benedetto Bruno,
  • Matteo Pelosini and
  • Sara Galimberti
  • + 1 author

4 June 2022

Background. In IWCLL guidelines, progressive splenomegaly and lymphadenopathy are signs of active disease. In this study, we have tested the hypotheses if US could be a reliable tool for both superficial lymphnodes (SupLNs) and splenic assessment in...

  • Article
  • Open Access
26 Citations
4,921 Views
20 Pages

Transglutaminases and Obesity in Humans: Association of F13A1 to Adipocyte Hypertrophy and Adipose Tissue Immune Response

  • Mari T. Kaartinen,
  • Mansi Arora,
  • Sini Heinonen,
  • Aila Rissanen,
  • Jaakko Kaprio and
  • Kirsi H. Pietiläinen

5 November 2020

Transglutaminases TG2 and FXIII-A have recently been linked to adipose tissue biology and obesity, however, human studies for TG family members in adipocytes have not been conducted. In this study, we investigated the association of TGM family member...

  • Article
  • Open Access
220 Views
14 Pages

Transcriptome- and Epigenome-Wide Association Studies of Tic Spectrum Disorder in Discordant Monozygotic Twins

  • Jonas Dalsberg,
  • Cathrine Jespersgaard,
  • Amanda M. Levy,
  • Anna Maria Asplund,
  • Frederik Otzen Bagger,
  • Nanette M. Debes,
  • Qihua Tan,
  • Zeynep Tümer and
  • Mathis Hildonen

18 January 2026

Background: Tic spectrum disorder (TSD), encompassing Tourette syndrome and chronic tic disorder, is a childhood-onset neurodevelopmental condition with complex genetic and environmental contributions. Heritable components have been implicated in TSD...

  • Review
  • Open Access
1,551 Views
10 Pages

5 December 2025

Blood pressure (BP) monitoring is essential in managing critically ill patients in the intensive care unit (ICU), particularly for ensuring adequate end-organ perfusion in hypotensive states. Invasive arterial catheters and noninvasive oscillometric...

  • Review
  • Open Access
34 Citations
5,563 Views
13 Pages

Emerging Treatment Options for Gastroenteropancreatic Neuroendocrine Tumors

  • Mauro Cives,
  • Eleonora Pelle’ and
  • Jonathan Strosberg

13 November 2020

Treatment options for neuroendocrine tumors (NETs) and carcinomas (NECs) are expanding. Early-phase studies have shown preliminary evidence of the antitumor activity of alpha-emitting peptide receptor radionuclide therapy (PRRT), and novel radiopepti...

  • Article
  • Open Access
4 Citations
3,501 Views
11 Pages

Detection of SF3B1 p.Lys700Glu Mutation by PNA-PCR Clamping in Myelodysplastic Syndromes and Myeloproliferative Neoplasms

  • Jessica Petiti,
  • Federico Itri,
  • Elisabetta Signorino,
  • Antonio Frolli,
  • Carmen Fava,
  • Marco Armenio,
  • Silvia Marini,
  • Emilia Giugliano,
  • Marco Lo Iacono and
  • Daniela Cilloni
  • + 1 author

25 February 2022

Mutations in SF3B1 are found in 20% of myelodysplastic syndromes and 5–10% of myeloproliferative neoplasms, where they are considered important for diagnosis and therapy decisions. Sanger sequencing and NGS are the currently available methods to iden...

  • Review
  • Open Access
30 Citations
36,652 Views
24 Pages

The Application of Creatine Supplementation in Medical Rehabilitation

  • Kylie K. Harmon,
  • Jeffrey R. Stout,
  • David H. Fukuda,
  • Patrick S. Pabian,
  • Eric S. Rawson and
  • Matt S. Stock

27 May 2021

Numerous health conditions affecting the musculoskeletal, cardiopulmonary, and nervous systems can result in physical dysfunction, impaired performance, muscle weakness, and disuse-induced atrophy. Due to its well-documented anabolic potential, creat...

  • Article
  • Open Access
18 Citations
4,147 Views
12 Pages

15 July 2021

The genetic structure and demography of the yellowbelly threadfin bream, Nemipterus bathybius, in the northern South China Sea were examined using the mitochondrial DNA cytochrome b gene (1141 bp). High levels of haplotype and nucleotide diversities...

  • Article
  • Open Access
2 Citations
1,089 Views
11 Pages

Predicted vs. Observed Prosthesis–Patient Mismatch After Surgical Aortic Valve Replacement

  • Giorgia Cibin,
  • Augusto D’Onofrio,
  • Giulia Lorenzoni,
  • Valentina Lombardi,
  • Emma Bergonzoni,
  • Assunta Fabozzo,
  • Irene Cao,
  • Andrea Francavilla,
  • Chiara Tessari and
  • Gino Gerosa
  • + 1 author

17 April 2025

Background and Objectives: Prosthesis–patient mismatch (PPM) after surgical aortic valve replacement (SAVR) is associated with worse clinical outcomes and worse valve durability. The aim of this retrospective single-center study was to evaluate...

  • Article
  • Open Access
1 Citations
1,357 Views
9 Pages

Comparison of Mitotic Count and Ki-67 Index in Grading Gastroenteropancreatic Neuroendocrine Tumors and Their Association with Metastases

  • Mohammad Sheikh-Ahmad,
  • Abed Agbarya,
  • Sharon Talisman,
  • Anan Shalata,
  • Hadas Rabani,
  • Jacob Bejar,
  • Hila Kreizman Shefer,
  • Reem Samara,
  • Forat Swaid and
  • Leonard Saiegh
  • + 7 authors

Background: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are graded per the World Health Organization (WHO) using mitotic count and the Ki-67 index. There is an ongoing debate regarding the concordance between these parameters and their ab...

  • Article
  • Open Access
8 Citations
3,375 Views
20 Pages

19 September 2022

Traditional classification based on morphological characters suggests that the genus Ostericum is closely related to Angelica, but molecular phylogenetic studies suggest that the genus Ostericum is related to Pternopetalum rather than Angelica. In th...

  • Article
  • Open Access
16 Citations
6,651 Views
8 Pages

Despite the enormous costs associated to mood disorders’, few studies evaluate potential cost saving from the use of pharmacogenetic tests (PGT). This study compares 12 months before the execution of the PGT versus 12 months after, in terms of...

  • Feature Paper
  • Article
  • Open Access
9 Citations
4,579 Views
25 Pages

Modeling and Observer-Based Monitoring of RAFT Homopolymerization Reactions

  • Patrick M. Lathrop,
  • Zhaoyang Duan,
  • Chen Ling,
  • Yossef A. Elabd and
  • Costas Kravaris

20 October 2019

Reversible addition–fragmentation chain–transfer (RAFT) polymerization of methyl methacrylate (MMA) is modeled and monitored using a multi-rate multi-delay observer in this work. First, to fit the RAFT reaction rate coefficients and the i...

  • Article
  • Open Access
14 Citations
5,933 Views
28 Pages

23 April 2020

Assessing the applicability of theory to major adaptive radiations in deep time represents an extremely difficult problem in evolutionary biology. Neoaves, which includes 95% of living birds, is believed to have undergone a period of rapid diversific...

  • Article
  • Open Access
2 Citations
2,784 Views
15 Pages

Sutureless Repair for Open Treatment of Inguinal Hernia: Three Techniques in Comparison

  • Enke Baldini,
  • Eleonora Lori,
  • Carola Morini,
  • Luigi Palla,
  • Diego Coletta,
  • Giuseppe M. De Luca,
  • Giorgio Giraudo,
  • Sergio G. Intini,
  • Bruno Perotti and
  • Piergaspare Palumbo
  • + 14 authors

19 January 2024

Currently, groin hernia repair is mostly performed with application of mesh prostheses fixed with or without suture. However, views on safety and efficacy of different surgical approaches are still partly discordant. In this multicentre retrospective...

  • Article
  • Open Access
20 Citations
6,061 Views
10 Pages

Actual vs. Perceived Motor Competence in Children (8–10 Years): An Issue of Non-Veridicality

  • Cain C. T. Clark,
  • Jason Moran,
  • Benjamin Drury,
  • Fotini Venetsanou and
  • John F. T. Fernandes

The purpose of this study was to investigate the between- and within-sex differences in actual and perceived locomotor and object control skills in children (8–10 year). All participants (58 children (29 boys; 9.5 ± 0.6 years; 1.44 ± 0.09 m; 39.6 ± 9...

  • Review
  • Open Access
71 Citations
15,872 Views
15 Pages

The Effects of Shift Work on Cardio-Metabolic Diseases and Eating Patterns

  • Alexandra Hemmer,
  • Julie Mareschal,
  • Charna Dibner,
  • Jacques A. Pralong,
  • Victor Dorribo,
  • Stephen Perrig,
  • Laurence Genton,
  • Claude Pichard and
  • Tinh-Hai Collet

22 November 2021

Energy metabolism is tightly linked with circadian rhythms, exposure to ambient light, sleep/wake, fasting/eating, and rest/activity cycles. External factors, such as shift work, lead to a disruption of these rhythms, often called circadian misalignm...

  • Article
  • Open Access
1,948 Views
9 Pages

17 December 2024

Introduction: Prostate biopsy results form the mainstay of patient care. However, there is often significant discordance between the biopsied histology and the ‘true’ histology shown on a radical prostatectomy (RP). Discordance in patholo...

  • Article
  • Open Access
995 Views
13 Pages

The Predictive Value of Preoperative Histological Risk Factors in Early Cervical Cancer

  • Jana Adams,
  • Amelie Wingels,
  • Constanze Amir-Kabirian,
  • Janice Katharina Jeschke,
  • Lara Gesemann,
  • Büsra Eser,
  • Caroline Lenz,
  • Bernd Morgenstern and
  • Fabinshy Thangarajah

8 May 2025

Background: Cervical cancer is a leading cause of morbidity and mortality among women globally. Currently, treatment is primarily based on tumor staging; however, discrepancies between preoperative and postoperative tumor staging remain a significant...

  • Article
  • Open Access
839 Views
18 Pages

27 October 2025

This study aimed to evaluate the effectiveness of a multimodal trust assessment approach that integrated electroencephalography (EEG) and self-report questionnaires compared with unimodal methods within the context of lower-limb rehabilitation traini...

  • Article
  • Open Access
2,938 Views
9 Pages

Barth Syndrome: Psychosocial Impact and Quality of Life Assessment

  • Anandbir Bath,
  • Oguz Akbilgic,
  • David Wilbanks,
  • Jay Patel,
  • Morgan Wallen,
  • Shereen Haji,
  • Arnab Das,
  • John Alexander,
  • Issa Pour-Ghaz and
  • John Jefferies
  • + 3 authors

Background: Barth syndrome (BTHS) is a rare X-linked genetic disease that affects multiple systems and leads to complex clinical manifestations. Although a considerable amount of research has focused on the physical aspects of the disease, less has f...

  • Feature Paper
  • Article
  • Open Access
1 Citations
2,559 Views
13 Pages

Flood-Related Federally Declared Disaster Events and Community Functioning (COPEWELL)

  • Norma F. Kanarek,
  • Qi Wang,
  • Tak Igusa,
  • Tara Kirk Sell,
  • Zachary Anthony Cox,
  • James M. Kendra and
  • Jonathan Links

23 October 2022

Objective: Understanding long-term disaster effects is key to building theories of recovery and informing policymaking. Findings regarding long-term recovery are inconsistent, with some scholars finding that disasters have little long-term impact, an...

  • Review
  • Open Access
31 Citations
5,136 Views
19 Pages

14 September 2020

Regulatory T cells represent a class of specialized T lymphocytes that suppress unwanted immune responses and size the activation of the immune system whereby limiting collateral damages in tissues involved by inflammation. In cancer, the accumulatio...

  • Article
  • Open Access
12 Citations
3,087 Views
10 Pages

Liquid Biopsy Is a Promising Tool for Genetic Testing in Idiopathic Pulmonary Fibrosis

  • Pierlorenzo Pallante,
  • Umberto Malapelle,
  • Mariantonia Nacchio,
  • Roberta Sgariglia,
  • Domenico Galati,
  • Ludovica Capitelli,
  • Serena Zanotta,
  • Mario Galgani,
  • Erica Piemonte and
  • Marialuisa Bocchino
  • + 2 authors

Liquid biopsy, which allows the isolation of circulating cell-free (ccf) DNA from blood, is an emerging noninvasive tool widely used in oncology for diagnostic and prognosis purposes. Previous data have shown that serum cfDNA discriminates idiopathic...

  • Review
  • Open Access
48 Citations
9,637 Views
14 Pages

Parental Influence on Child and Adolescent Physical Activity Level: A Meta-Analysis

  • Diana L. Y. Su,
  • Tracy C. W. Tang,
  • Joan S. K. Chung,
  • Alfred S. Y. Lee,
  • Catherine M. Capio and
  • Derwin K. C. Chan

Parents are often regarded as one of the significant social agents who are important to the participation of physical activity (PA) among children and adolescents. However, within the literature, the relationships between parental influences and chil...

  • Article
  • Open Access
2 Citations
3,471 Views
17 Pages

Impact of Neoadjuvant Therapy on PD-L1 Expression in Triple-Negative Breast Cancer and Correlation with Clinicopathological Factors

  • Nevena Ilieva,
  • Mina Pencheva,
  • Hristo Hadzhiev,
  • Desislava Tashkova,
  • Elena Daskalova,
  • Petar Georgiev and
  • Sylvia Genova

27 November 2024

Background: This study aims to deliver more insights on the impact of neoadjuvant treatment on Pd-L1 expression and to evaluate its correlation with clinicopathological factors. Methods: We reviewed 88 TNBC cases for the period 2021–2023. Data...

  • Article
  • Open Access
13 Citations
5,173 Views
11 Pages

14 December 2021

The emergence of multidrug resistant Gram-negative pathogens, particularly carbapenemase producers, has forced clinicians to use last line antibiotics, such as colistin. Since colistin susceptibility testing presents several challenges, this study ai...

  • Article
  • Open Access
1 Citations
2,570 Views
25 Pages

14 January 2023

Imaging and genetic studies have characterized biological risk factors contributing to specific reading disability (SRD). The current study aimed to apply this literature to a family of twins discordant for SRD and an older sibling with reading diffi...

  • Case Report
  • Open Access
23,774 Views
5 Pages

The Alice in Wonderland Syndrome (AIWS) is an unusual and uncommon condition that falls under the umbrella of neurology and psychiatry. It is characterized by the presence of complex perceptual and visual discord. Additionally, there are visual hallu...

  • Systematic Review
  • Open Access
33 Citations
16,177 Views
17 Pages

Effectiveness of Whey Protein Supplementation during Resistance Exercise Training on Skeletal Muscle Mass and Strength in Older People with Sarcopenia: A Systematic Review and Meta-Analysis

  • Iván Cuyul-Vásquez,
  • José Pezo-Navarrete,
  • Cristina Vargas-Arriagada,
  • Cynthia Ortega-Díaz,
  • Walter Sepúlveda-Loyola,
  • Sandro Massao Hirabara and
  • Gabriel Nasri Marzuca-Nassr

2 August 2023

Objective: To determine the effectiveness of whey protein (WP) supplementation during resistance exercise training (RET) vs. RET with or without placebo supplementation on skeletal muscle mass, strength, and physical performance in older people with...

  • Systematic Review
  • Open Access
3 Citations
2,589 Views
13 Pages

A limited number of studies investigated the association between the ABO blood groups and the incidence of venous thromboembolism in individuals with Factor V Leiden; however, discordant findings were reported. Consequently, this systematic review an...

  • Review
  • Open Access
3 Citations
4,639 Views
15 Pages

Navigating the Uncertainty of B3 Breast Lesions: Diagnostic Challenges and Evolving Management Strategies

  • Sabatino D’Archi,
  • Beatrice Carnassale,
  • Alejandro Martin Sanchez,
  • Cristina Accetta,
  • Paolo Belli,
  • Flavia De Lauretis,
  • Enrico Di Guglielmo,
  • Alba Di Leone,
  • Antonio Franco and
  • Gianluca Franceschini
  • + 6 authors

18 January 2025

B3 breast lesions, classified as lesions of uncertain malignant potential, present a significant diagnostic and therapeutic challenge due to their heterogeneous nature and variable risk of progression to malignancy. These lesions, which include atypi...

  • Article
  • Open Access
1 Citations
2,121 Views
11 Pages

Factors Influencing Community Pharmacists’ Participation in Antimicrobial Stewardship: A Qualitative Inquiry

  • Tasneem Rizvi,
  • Syed Tabish R. Zaidi,
  • Mackenzie Williams,
  • Angus Thompson and
  • Gregory M. Peterson

14 April 2025

Very few studies, all employing surveys, have investigated the perceptions of community pharmacists regarding antimicrobial stewardship (AMS). A qualitative inquiry exploring factors affecting community pharmacists’ participation in AMS may ass...

  • Article
  • Open Access
32 Citations
13,931 Views
16 Pages

Segmentation and Grade Prediction of Colon Cancer Digital Pathology Images Across Multiple Institutions

  • Saima Rathore,
  • Muhammad Aksam Iftikhar,
  • Ahmad Chaddad,
  • Tamim Niazi,
  • Thomas Karasic and
  • Michel Bilello

1 November 2019

Distinguishing benign from malignant disease is a primary challenge for colon histopathologists. Current clinical methods rely on qualitative visual analysis of features such as glandular architecture and size that exist on a continuum from benign to...

  • Case Report
  • Open Access
2 Citations
2,111 Views
9 Pages

ST-Segment Elevation: An Unexpected Culprit

  • David Sá Couto,
  • André Alexandre,
  • Ricardo Costa,
  • Andreia Campinas,
  • Mariana Santos,
  • Diana Ribeiro,
  • Severo Torres and
  • André Luz

The clinical presentation of pulmonary embolism (PE) and acute coronary syndrome can be similar. We report a case of a patient presenting with antero-septal ST-segment elevation after cardiac arrest, found to have acute-PE-mimicking ST-segment elevat...

  • Review
  • Open Access
3 Citations
4,215 Views
29 Pages

Inquiry of the Metabolic Traits in Relationship with Daily Magnesium Intake: Focus on Type 2 Diabetic Population

  • Ana-Maria Gheorghe,
  • Mihai-Lucian Ciobica,
  • Claudiu Nistor,
  • Maria-Magdalena Gurzun,
  • Bianca-Andreea Sandulescu,
  • Mihaela Stanciu,
  • Florina Ligia Popa and
  • Mara Carsote

8 July 2024

Magnesium (Mg), an essential nutrient with a wide area of physiological roles, stands as a cofactor in over 600 enzymatic reactions involved in the synthesis of proteins and nucleic acids, DNA repair, neuromuscular functions, neuronal transmission, c...

  • Review
  • Open Access
6 Citations
3,038 Views
11 Pages

Echocardiographic Parameters for Risk Prediction in Borderline Right Ventricle: Review with Special Emphasis on Pulmonary Atresia with Intact Ventricular Septum and Critical Pulmonary Stenosis

  • Massimiliano Cantinotti,
  • Colin Joseph McMahon,
  • Pietro Marchese,
  • Martin Köstenberger,
  • Marco Scalese,
  • Eliana Franchi,
  • Giuseppe Santoro,
  • Nadia Assanta,
  • Xander Jacquemyn and
  • Raffaele Giordano
  • + 1 author

10 July 2023

The aim of the present review is to highlight the strengths and limitations of echocardiographic parameters and scores employed to predict favorable outcome in complex congenital heart diseases (CHDs) with borderline right ventricle (RV), with a focu...

  • Article
  • Open Access
2 Citations
2,855 Views
12 Pages

Accurate and Automated Genotyping of the CFTR Poly-T/TG Tract with CFTR-TIPS

  • Qiliang Ding,
  • Christopher D. Hofich,
  • Tifani B. Kellogg,
  • Rhonda K. Kuennen,
  • Kaitlin N. Paxton,
  • Sarah M. Thieke,
  • Kandelaria M. Rumilla and
  • Linda Hasadsri

Cystic fibrosis is caused by biallelic pathogenic variants in the CFTR gene, which contains a polymorphic (TG)mTn sequence (the “poly-T/TG tract”) in intron 9. While T9 and T7 alleles are benign, T5 alleles with longer TG repeats, e.g., (...

  • Article
  • Open Access
1 Citations
1,487 Views
16 Pages

16 October 2024

The genus Pourthiaea Decne., a deciduous woody group with high ornamental value, belongs to the family Rosaceae. Here, we reported newly sequenced plastid genome sequences of Pourthiaea beauverdiana (C. K. Schneid.) Hatus., Pourthiaea parvifolia E. P...

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