The growing concerns over road safety and the increasing popularity of two-wheeled vehicles highlight the need to address aggressive driving behaviors in this context. Understanding and detecting such behaviors can significantly contribute to rider s...
The increasing concern for road safety has driven the development of advanced driver behavior analysis systems. This study presents a comprehensive review of various techniques to detect unsafe driving behaviors, with a particular emphasis on using s...
23 June 2022
Driving behavior is considered one of the most important factors in all road crashes, accounting for 40% of all fatal and serious accidents. Moreover, aggressive driving is the leading cause of traffic accidents that jeopardize human life and propert...
This paper suggests a new multi-lane lattice model that incorporates both overtaking mechanisms and drivers’ aggressive lane-changing behaviors to investigate macroscopic traffic stability in multi-lane expressway environments. To enhance the f...
In most animals, males are considered more aggressive, in terms of frequency and intensity of aggressive behaviors, than their female peers. However, in several species this widespread male-biased aggression pattern is either extenuated, absent, or e...
Urban transportation is a major source of air pollution. On urban highways, driver behavior significantly influences vehicle emissions, as tailpipe pollutants depend on driving patterns. Therefore, estimating the emission factors of key pollutants na...
This article presents a model-based approach to assess the battery performance of a two-wheeler EV drive train system for various user driving patterns using the selected urban drive cycles. The battery pack is one of the most expensive parts of an E...
Thyroid Cancer (TC) is the most common endocrine malignancy, with increasing incidence globally. Papillary thyroid cancer (PTC), a differentiated form of TC, accounts for approximately 90% of TC and occurs predominantly in women of childbearing age....
The acidic pH of the tumor microenvironment plays a critical role in driving cancer development toward a more aggressive phenotype, but the underlying mechanisms are unclear. To this end, phenotypic and genotypic changes induced by adaptation of canc...
The integration of autonomous vehicles into urban traffic systems offers a significant opportunity to improve traffic efficiency and safety at signalized intersections. This study provides a comprehensive evaluation of how different autonomous vehicl...
In the last few decades, epigenetics has emerged as an exciting new field in development and disease, with a more recent focus towards cancer. Epigenetics has classically referred to heritable patterns of gene expression, primarily mediated through D...
This paper presents a new methodology to evaluate the performance of an electric vehicle hybrid power system consisting of a fuel cell and a supercapacitor. The study compares the results to those obtained for a battery electric vehicle. The methodol...
To address the ‘mechanical’ return to original lane and similar non-humanized lane-changing issues that may occur in existing intelligent driving systems after completing overtaking maneuvers, this study proposes a humanized lane-changing...
Mobility in urban and interurban areas, mainly by cars, is a day-to-day activity of many people. However, some of its main drawbacks are traffic jams and accidents. Newly made vehicles have pre-installed driving evaluation systems, which can prevent...
This work explores the classification of driving behaviors using a hybrid deep learning model that combines Convolutional Neural Networks (CNNs) with Long Short-Term Memory (LSTM) networks (ConvLSTM). Sensor data are collected from a smartphone appli...
One of the alarming aspects of Bangladesh’s traffic safety is the massive growth in the number of drivers without previous driving instruction or licenses. Proper traffic safety is defined as systems and techniques used to safeguard road users...
With the rapid and wide implementation of adaptive cruise control system (ACC), the testing and evaluation method becomes an important question. Based on the human driver behavior characteristics extracted from naturalistic driving studies (NDS), thi...
Colorectal cancer (CRC) is a significant worldwide health problem due to its high prevalence, mortality rates, and frequent diagnosis at advanced stages. While diagnostic and therapeutic approaches have evolved, the underlying mechanisms driving CRC...
This study explores road users’ behaviors and accident analyses on different travel modes in the Bangkok Metropolitan Region (BMR). The questionnaire survey was adopted and designed based on contributing factors related to risk behavior percept...
Background/Objectives: Neuroblastoma is a highly aggressive pediatric cancer that arises from immature nerve cells and exhibits a broad spectrum of clinical presentations. While low- and intermediate-risk neuroblastomas often have favorable outcomes,...
Pediatric high-grade gliomas are a devastating subset of brain tumors, characterized by their aggressive pathophysiology and limited treatment options. Among them, H3 K27-altered diffuse midline gliomas (DMG) of the brainstem stand out due to their d...
Lithium-ion batteries are widely used in electric vehicles (EVs) due to their high energy and power density. The accurate prediction of Remaining Useful Life (RUL) is critical for ensuring safety, reliability, and optimal battery utilization. However...
Chordomas are rare tumors of the embryologic spinal cord remnant. They are locally aggressive and typically managed with surgery and either adjuvant or neoadjuvant radiation therapy. However, there is great variability in practice patterns including...
With the deep development of tight reservoir in Mahu Sag, the trend of rising water cut during flowback concerns engineers, and its control mechanism is not yet clear. For this purpose, the integrated numerical model of horizontal well pattern from f...
Chordomas, arising from notochord remnants, are rare neoplasms with aggressive growth patterns despite their histologically low-grade nature. This review explores their embryological origins, molecular markers like brachyury, and genetic alterations...
As part of broader research efforts to understand the factors contributing to crashes involving younger drivers, it is important to characterize the crash contributing factors of the at-fault younger drivers. This study applied latent class analysis...
Background: Centrosome amplification, a hallmark of cell cycle dysregulation, drives carcinogenesis through aneuploidy induction and invasive phenotype acquisition. In pancreatic adenocarcinoma—a malignancy characterized by profound genomic ins...
The pituitary gland is one of the most cellularly diverse regions of the brain. Recent advancements in transcriptomic biology, such as single-cell RNA sequencing, bring an unprecedented glimpse into the molecular composition of the pituitary, both in...
Pancreatic ductal adenocarcinoma (PDAC) is a devastating and highly aggressive malignancy. Existing therapeutic strategies only provide a small survival benefit in patients with PDAC. Laboratory and clinical research have identified various populatio...
Tumor stemness represents a key biological process that drives tumor progression and therapeutic resistance across various cancer types. To systematically elucidate the regulatory roles of long non-coding RNAs (lncRNAs) in this process, we integrated...
Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is a key regulator of cancer stem cell (CSC) biology and signaling. In CSCs, ROR1 acts as a receptor or co-receptor, interacting with non-canonical WNT ligands, and forming complexes with protein...
Diffuse intrinsic pontine glioma (DIPG), now referred to as diffuse midline glioma (DMG), is a highly aggressive pediatric cancer primarily affecting children aged 4 to 9 years old. Despite the research and clinical trials conducted to identify a pos...
Breast cancer (BC) is the most prevalent malignancy among women, characterized by extensive heterogeneity stemming from molecular and genetic alterations. This review explores the intricate epigenetic landscape of BC, highlighting the significant rol...
Metastasis is the major cause of cancer deaths and control of gene transcription has emerged as a critical contributing factor. RhoA- and RhoC-induced gene transcription via the actin-regulated transcriptional co-activator megakaryocytic leukemia (MK...
Solid-State Drives (SSDs) have become the dominant storage medium in performance-sensitive systems due to their high throughput, reliability, and energy efficiency. However, inherent constraints in NAND flash memory—such as out-of-place writes,...
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, highlighting the need for a deeper understanding of the genetic mechanisms driving its development and progression. Identifying genetic mutations that affect key m...
Background: Glioblastoma (GBM) is the deadliest and most common brain tumor in adults, with poor survival and response to aggressive therapy. Limited access of drugs to tumor cells is one reason for such grim clinical outcomes. A driving force for th...
Background: Aberrant RON signaling is present in numerous cancers including breast cancer. Evidence suggests that the ligand, hepatocyte growth factor-like (HGFL), is also overexpressed in breast cancer. RON (MST1R) and HGFL (MST1) genes are located...
Glioblastoma multiforme (GBM) is the most aggressive primary brain cancer (with a median survival time of 14.5 months), characterized by heterogeneity. Identifying prognostic molecular subtypes could provide a deeper exposition of GBM biology with po...
Background/Objectives: High-grade gliomas (HGGs), including glioblastomas, are among the most aggressive brain tumors due to their high intratumoral heterogeneity and extensive infiltration. Glioma stem-like cells (GSCs) frequently invade along white...
Understanding spatial characteristics of urban building systems is critical for unraveling urban building stock growth patterns, addressing housing vacancy challenges, and advancing urban carbon neutrality. However, existing research on built environ...
Glioblastoma (GBM) is an aggressive brain tumor characterized by molecular complexity and resistance to conventional treatments, including surgery, radiation, and chemotherapy. Despite these challenges, advancements in receptor tyrosine kinase (RTK)...
Gastric cancer remains a major global health burden, with limited response rates to current immunotherapies targeting the programmed death-ligand 1 (PD-1/PD-L1) axis. Recent studies have identified sialic acid-binding immunoglobulin-like lectin 15 (S...
Background and aim: Ever since the discovery of tumor-associated immune cells, there has been growing interest in the understanding of the mechanisms underlying the crosstalk between these cells and tumor cells. A “seed and soil” approach...
Glioblastoma is an aggressive and prevalent form of brain cancer characterized by rapid tumor cell migration and invasion into surrounding healthy tissues, making it resistant to conventional treatments. Despite advances in therapeutic approaches, pa...
Introduction: Meningiomas are the most common primary central nervous system tumors, constituting 39.7% of intracranial tumors. Although generally benign, some exhibit aggressive behavior and risk of recurrence, necessitating adjuvant therapy and rep...
The impact of invasive alien species (IAS) is one of the direct factors causing global biodiversity decline and economic losses, and predicting the potential invasion risks of invasive species is crucial for developing prevention and control strategi...
Background: Oral squamous cell carcinoma (OSCC), which accounts for over 90% of all oral malignancies, remains a major global health challenge due to its aggressive clinical course and poor prognosis. Periodontitis, a widespread chronic inflammatory...