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235 Results Found

  • Review
  • Open Access
14 Citations
5,957 Views
18 Pages

This review explains the origin of the LIV-1 family of zinc transporters, paying attention to how this family of nine human proteins was originally discovered. Structural and functional differences between these nine human LIV-1 family members and th...

  • Review
  • Open Access
108 Citations
14,492 Views
28 Pages

4 July 2012

Zinc is a trace mineral which is vital for the functioning of numerous cellular processes, is critical for growth, and may play an important role in cancer etiology and outcome. The intracellular levels of this mineral are regulated through the coord...

  • Review
  • Open Access
5 Citations
63,470 Views
10 Pages

Clinical and Safety Evaluation of Liv.52 in Alcoholic Liver Disease: A Review

  • Subramanian Ganesh,
  • Neeraj Joshi,
  • Mukesh Kumar Jain,
  • Lokendra Sharma,
  • Anish Desai,
  • Mohamed Rafiq,
  • Uddagiri Venkanna Babu and
  • Rajesh Kumawat

Alcoholic liver disease (ALD) has been a growing concern in developed and developing nations. Oxidative stress and lipid peroxidation are the most common cause of the development and progression of ALD. Due to paucity in the number and efficacy of he...

  • Review
  • Open Access
12 Citations
103,850 Views
16 Pages

Hepatoprotective Effects of Liv.52 in Chronic Liver Disease Preclinical, Clinical, and Safety Evidence: A Review

  • Chetan Kantharia,
  • Munesh Kumar,
  • Mukesh Kumar Jain,
  • Lokendra Sharma,
  • Lokesh Jain and
  • Anish Desai

Chronic liver disease (CLD) is a growing concern worldwide. The common etiological factors include infection, alcohol abuse, exposure to hepatotoxic drugs, autoimmune disorders, and metabolic diseases. The chronic liver disease progresses to liver ci...

  • Article
  • Open Access
501 Views
14 Pages

Mitigating Hydroxychloroquine-Induced Oxidative Liver Damage: The Roles of Adenosine Triphosphate, Liv-52, and Their Combination in Rats

  • Meryem Yalvac Kandefer,
  • Esra Tuba Sezgin,
  • Bahadir Suleyman,
  • Ferda Keskin Cimen,
  • Fulya Memiş,
  • Mine Gulaboglu and
  • Halis Suleyman

31 December 2025

Hydroxychloroquine (HCQ), originally developed as an antimalarial agent, has been associated with hepatotoxic effects in experimental and clinical settings. Our study was designed to evaluate the effects of this agent on liver toxicity and to underst...

  • Feature Paper
  • Article
  • Open Access
4 Citations
3,974 Views
15 Pages

Prognostic and Predictive Value of LIV1 Expression in Early Breast Cancer and by Molecular Subtype

  • Alexandre de Nonneville,
  • Pascal Finetti,
  • Laurys Boudin,
  • Emilie Denicolaï,
  • Daniel Birnbaum,
  • Emilie Mamessier and
  • François Bertucci

Background: LIV1 is a transmembrane protein that may become a new therapeutic target through the development of antibody–drug conjugates (ADCs). Few studies are available regarding the assessment of LIV1 expression in clinical breast cancer (BC...

  • Article
  • Open Access
1 Citations
3,470 Views
10 Pages

Establishment and Characterization of a New Human Intrahepatic Cholangiocarcinoma Cell Line LIV27

  • Xiwei Ding,
  • Kais Zakharia,
  • Catherine D. Moser,
  • Nellie A. Campbell,
  • Chunling Hu,
  • Nataliya Razumilava,
  • Roongruedee Chaiteerakij,
  • Hassan M. Shaleh,
  • Patricia T. Greipp and
  • Lewis R. Roberts
  • + 3 authors

17 October 2022

Cholangiocarcinoma (CCA) is a highly lethal cancer arising from the biliary tract epithelium. The cancer biology of this neoplasm is not well understood. To date, only a few CCA cell lines have been reported, which were mostly developed from Asian pa...

  • Article
  • Open Access
1 Citations
1,415 Views
24 Pages

9 December 2024

To meet the needs of English learners (ELs) and the call of the Next Generation Science Standards to engage all students in communicating science ideas, a collaboration between science, second language acquisition, and disciplinary literacy teacher e...

  • Article
  • Open Access
5 Citations
2,973 Views
13 Pages

Influence of Lateral Translation of Lowest Instrumented Vertebra on L4 Tilt and Coronal Balance for Thoracolumbar and Lumbar Curves in Adolescent Idiopathic Scoliosis

  • Katsuhisa Yamada,
  • Hideki Sudo,
  • Yuichiro Abe,
  • Terufumi Kokabu,
  • Hiroyuki Tachi,
  • Tsutomu Endo,
  • Takashi Ohnishi,
  • Daisuke Ukeba,
  • Katsuro Ura and
  • Norimasa Iwasaki
  • + 1 author

9 February 2023

This study aimed to evaluate the lowest instrumented vertebra translation (LIV-T) in the surgical treatment of thoracolumbar/lumbar adolescent idiopathic scoliosis and to analyze the radiographic parameters in relation to LIV-T and L4 tilt and global...

  • Article
  • Open Access
1 Citations
2,219 Views
8 Pages

What Is the Role of Traction Test Radiographs in the Preoperative Planning of Adolescent Idiopathic Scoliosis?

  • Giovanni Andrea La Maida,
  • Enrico Gallazzi,
  • Federica Ramella,
  • Marcello Ferraro,
  • Andrea Della Valle,
  • Davide Cecconi and
  • Bernardo Misaggi

8 November 2023

Lower instrumented vertebra (LIV) selection is critical to avoid complications like adding-on. This study aims to determine the usefulness of the traction test (TR) in selecting the LIV during surgery for adolescent idiopathic scoliosis (AIS). We ana...

  • Article
  • Open Access
1,293 Views
18 Pages

Real-Time Geo-Localization for Land Vehicles Using LIV-SLAM and Referenced Satellite Imagery

  • Yating Yao,
  • Jing Dong,
  • Songlai Han,
  • Haiqiao Liu,
  • Quanfu Hu and
  • Zhikang Chen

24 July 2025

Existing Simultaneous Localization and Mapping (SLAM) algorithms provide precise local pose estimation and real-time scene reconstruction, widely applied in autonomous navigation for land vehicles. However, the odometry of SLAM algorithms exhibits lo...

  • Article
  • Open Access
406 Views
14 Pages

5 January 2026

In the spacetime of a charged rotating accelerated black hole, the dynamics equations of fermions and bosons are modified by Lorentz invariance violation (LIV). The correction effects of LIV on the quantum tunneling radiation of this black hole are i...

  • Review
  • Open Access
1,632 Views
19 Pages

21 August 2025

Zinc is an essential trace element involved in critical physiological functions such as gene expression, immune regulation, and cellular proliferation. This review explores the link between zinc homeostasis and cancer, with a specific focus on LIV-1...

  • Article
  • Open Access
2,670 Views
17 Pages

The spread of biometric systems utilizing fingerprints has increased the need for advanced spoof detection techniques, but training convolutional neural networks (CNNs) with the limited number of images available in fingerprint datasets poses signifi...

  • Article
  • Open Access
1 Citations
2,831 Views
14 Pages

17 January 2023

The stability of Li3.8Ge0.9S0.1O4 lithium-conducting solid electrolyte versus lithium metal and Li–V bronze Li1.3V3O8 is studied in the present research. Isothermal heat treatment and thermal analysis of the mixtures of Li1.3V3O8 and Li3.8Ge0.9...

  • Article
  • Open Access
20 Citations
5,580 Views
13 Pages

26 March 2017

LiV3O8/polytriphenylamine composites are synthesized by a chemical oxidative polymerization process and applied as cathode materials for rechargeable lithium batteries (RLB). The structure, morphology, and electrochemical performances of the composit...

  • Case Report
  • Open Access
2 Citations
2,498 Views
5 Pages

5 February 2022

We report our experience in treating a ruptured dissecting posterior inferior cerebellar artery (PICA) aneurysm. To our knowledge, this is the first reported case of overlapping stenting without coils for a ruptured dissecting aneurysm of the proxima...

  • Article
  • Open Access
16 Citations
6,400 Views
11 Pages

18 February 2020

An improved method of physical activity accelerometer data processing, involving a wider frequency filter than the most commonly used ActiGraph filter, has been shown to better capture variations in physical activity intensity in a lab setting. The a...

  • Article
  • Open Access
802 Views
16 Pages

9 June 2025

The Living Well with Dementia (LivDem) group intervention aims to support people to adjust following a diagnosis of dementia and is delivered across the UK and abroad. However, LivDem was designed for older people with dementia and may not address th...

  • Article
  • Open Access
10 Citations
4,881 Views
16 Pages

Real-Time Optical Detection of Isoleucine in Living Cells through a Genetically-Encoded Nanosensor

  • Shruti Singh,
  • Maheshwar Prasad Sharma,
  • Abdulaziz A. Alqarawi,
  • Abeer Hashem,
  • Elsayed Fathi Abd_Allah and
  • Altaf Ahmad

25 December 2019

Isoleucine is one of the branched chain amino acids that plays a major role in the energy metabolism of human beings and animals. However, detailed investigation of specific receptors for isoleucine has not been carried out because of the non-availab...

  • Article
  • Open Access
8 Citations
4,478 Views
11 Pages

24 June 2019

We developed a novel battery system consisting of a hybrid (LiCoO2 + LiV3O8) cathode in a cell with a hybrid (graphite + Li-metal) anode and compared it with currently used systems. The hybrid cathode was synthesized using various ratios of LiCoO2:Li...

  • Article
  • Open Access
649 Views
13 Pages

17 December 2025

Background: Deep learning models have been used in the past for non-invasive liver fibrosis classification based on liver ultrasound scans. After numerous improvements in the network architectures, optimizers, and development of hybrid methods, the p...

  • Article
  • Open Access
4 Citations
2,662 Views
13 Pages

Given the relevance of lithium and post-lithium batteries as electrochemical energy storage systems, the peculiar crystalline structure of V2O5 and its doping capacity play key roles in lithium-ion battery technology. To integrate them in high-effici...

  • Article
  • Open Access
2,258 Views
15 Pages

A Concept of Assessment of LIV Tests with THESEUS Using the Gamma-Ray Bursts Detected by Fermi/GBM

  • Anastasia Tsvetkova,
  • Luciano Burderi,
  • Alessandro Riggio,
  • Andrea Sanna and
  • Tiziana Di Salvo

According to Einstein’s special relativity theory, the speed of light in a vacuum is constant for all observers. However, quantum gravity effects could introduce its dispersion depending on the energy of photons. The investigation of the spectr...

  • Article
  • Open Access
15 Citations
4,944 Views
12 Pages

High-Capacity and Long-Lifespan Aqueous LiV3O8/Zn Battery Using Zn/Li Hybrid Electrolyte

  • Qiang Pang,
  • Xiangyu Yu,
  • Shijing Zhang,
  • Wei He,
  • Siyu Yang,
  • Yao Fu,
  • Ying Tian,
  • Mingming Xing and
  • Xixian Luo

Aqueous zinc-ion batteries (AZIBs) are promising candidates for large-scale energy storage because of their low cost and high safety. However, their practical applications are impeded by low energy density and short service life. Here, an aqueous Zn2...

  • Review
  • Open Access
8 Citations
11,552 Views
14 Pages

A Systematic Literature Review of Loneliness in Community Dwelling Older Adults

  • Gabriela Di Perna,
  • Katrina Radford,
  • Gaery Barbery and
  • Janna Anneke Fitzgerald

28 December 2022

Research on loneliness is extensive. This paper presents a systematic review of intervention studies, outlining the antecedents to, and consequences of loneliness in community-dwelling older people. Using PRISMA methodology, a systematic literature r...

  • Article
  • Open Access
978 Views
20 Pages

Lightning-Induced Voltages over Gaussian-Shaped Terrain Considering Different Lightning Strike Locations

  • Jiawei Niu,
  • Jinbo Zhang,
  • Yan Tao,
  • Junhua Zou,
  • Qilin Zhang,
  • Zhibin Xie,
  • Yajun Wang and
  • Xiaolong Li

7 June 2025

Lightning-induced voltages (LIVs) computation is crucial for lightning protection of power systems and equipment, yet the effect of complex terrain on LIVs remains not fully evaluated. This study establishes a three-dimensional finite-difference time...

  • Article
  • Open Access
17 Citations
5,392 Views
14 Pages

Low-Intensity Vibration Improves Muscle Healing in a Mouse Model of Laceration Injury

  • Thomas F. Corbiere,
  • Eileen M. Weinheimer-Haus,
  • Stefan Judex and
  • Timothy J. Koh

Recovery from traumatic muscle injuries is typically prolonged and incomplete, leading to impaired muscle and joint function. We sought to determine whether mechanical stimulation via whole-body low-intensity vibration (LIV) could (1) improve muscle...

  • Article
  • Open Access
5 Citations
2,867 Views
12 Pages

30 June 2024

Background/Objectives: There is no solid consensus regarding which lowest instrumented vertebra (LIV) selection criterion is best to prevent distal adding-on (DA) after adolescent idiopathic scoliosis (AIS) surgery. This study aims to search out the...

  • Review
  • Open Access
3 Citations
2,500 Views
16 Pages

Ultra-High-Energy Astroparticles as Probes for Lorentz Invariance Violation

  • Rodrigo Guedes Lang,
  • Humberto Martínez-Huerta and
  • Vitor de Souza

22 August 2022

Compelling evidence for Lorentz invariance violation (LIV) would demand a complete revision of modern physics. Therefore, searching for a signal or extending the validity of the invariance is fundamental for building our understanding of the extreme...

  • Article
  • Open Access
64 Citations
10,112 Views
12 Pages

Effects of Frequency Filtering on Intensity and Noise in Accelerometer-Based Physical Activity Measurements

  • Jonatan Fridolfsson,
  • Mats Börjesson,
  • Christoph Buck,
  • Örjan Ekblom,
  • Elin Ekblom-Bak,
  • Monica Hunsberger,
  • Lauren Lissner and
  • Daniel Arvidsson

11 May 2019

In objective physical activity (PA) measurements, applying wider frequency filters than the most commonly used ActiGraph (AG) filter may be beneficial when processing accelerometry data. However, the vulnerability of wider filters to noise has not be...

  • Feature Paper
  • Article
  • Open Access
951 Views
18 Pages

28 January 2025

Recently there have been several studies devoted to the investigation of the fate of fundamental relativistic symmetries at the foreseen unification of gravity and quantum regime, that is the Planck scale. In order to preserve covariance of the formu...

  • Article
  • Open Access
1,428 Views
17 Pages

25 February 2025

Background: Epizootics of largemouth bass ranavirus (LMBRaV) in largemouth bass (Micropterus salmoides) populations are associated with elevated mortality and significant financial losses. Given the lack of effective and safe medication to treat this...

  • Article
  • Open Access
3 Citations
2,939 Views
13 Pages

Left Ventricular Function and Iron Loading Status in a Tertiary Center Hemochromatosis Cohort—A Cardiac Magnetic Resonance Study

  • Karolina Dorniak,
  • Ludmiła Daniłowicz-Szymanowicz,
  • Katarzyna Sikorska,
  • Katarzyna Rozwadowska,
  • Jadwiga Fijałkowska,
  • Anna Glińska,
  • Magdalena Tuzimek,
  • Agnieszka Sabisz,
  • Marta Żarczyńska-Buchowiecka and
  • Edyta Szurowska
  • + 2 authors

28 October 2022

Background: Haemochromatosis (HCH), a common genetic disorder with variable penetrance, results in progressive but understudied iron overload. We prospectively evaluated organ iron loading and cardiac function in a tertiary center HCH cohort. Methods...

  • Article
  • Open Access
16 Citations
5,182 Views
20 Pages

Lamin A/C Is Dispensable to Mechanical Repression of Adipogenesis

  • Matthew Goelzer,
  • Amel Dudakovic,
  • Melis Olcum,
  • Buer Sen,
  • Engin Ozcivici,
  • Janet Rubin,
  • Andre J. van Wijnen and
  • Gunes Uzer

Mesenchymal stem cells (MSCs) maintain the musculoskeletal system by differentiating into multiple lineages, including osteoblasts and adipocytes. Mechanical signals, including strain and low-intensity vibration (LIV), are important regulators of MSC...

  • Article
  • Open Access
8 Citations
3,046 Views
13 Pages

Dual-Model Synergy for Fingerprint Spoof Detection Using VGG16 and ResNet50

  • Mohamed Cheniti,
  • Zahid Akhtar and
  • Praveen Kumar Chandaliya

4 February 2025

In this paper, we address the challenge of fingerprint liveness detection by proposing a dual pre-trained model approach that combines VGG16 and ResNet50 architectures. While existing methods often rely on a single feature extraction model, they may...

  • Article
  • Open Access
57 Citations
6,201 Views
19 Pages

Biofabricated Fatty Acids-Capped Silver Nanoparticles as Potential Antibacterial, Antifungal, Antibiofilm and Anticancer Agents

  • Mohammad Azam Ansari,
  • Sarah Mousa Maadi Asiri,
  • Mohammad A. Alzohairy,
  • Mohammad N. Alomary,
  • Ahmad Almatroudi and
  • Firdos Alam Khan

9 February 2021

The current study demonstrates the synthesis of fatty acids (FAs) capped silver nanoparticles (AgNPs) using aqueous poly-herbal drug Liv52 extract (PLE) as a reducing, dispersing and stabilizing agent. The NPs were characterized by various techniques...

  • Review
  • Open Access
21 Citations
4,891 Views
30 Pages

27 February 2020

This work explores the possibility of resorting to neutrino phenomenology to detect evidence of new physics, caused by the residual signals of the supposed quantum structure of spacetime. In particular, this work investigates the effects on neutrino...

  • Article
  • Open Access
4 Citations
1,395 Views
9 Pages

We reanalyze the spectral lag data for 56 Gamma-Ray Bursts (GRBs) in the cosmological rest frame to search for Lorentz Invariance Violation (LIV) using frequentist inference. For this purpose, we use the technique of profile likelihood to deal with t...

  • Review
  • Open Access
38 Citations
6,956 Views
14 Pages

Lorentz Invariance Violation Tests in Astroparticle Physics

  • Humberto Martínez-Huerta,
  • Rodrigo Guedes Lang and
  • Vitor de Souza

27 July 2020

In this review, we present the latest exclusion limits obtained from astroparticles on Lorentz Invariance Violation (LIV) in the photon sector. We discuss the techniques known as energy-dependent time delay or time lag, subluminal pair production thr...

  • Article
  • Open Access
5 Citations
4,182 Views
15 Pages

Survival of Patients with Alcohol-Related Liver Disease Cirrhosis—Usefulness of the New Liver Mortality Inpatients Prognostic Score

  • Vera Matovic Zaric,
  • Ivana Pantic,
  • Sofija Lugonja,
  • Tijana Glisic,
  • Snezana Konjikusic,
  • Iva Lolic,
  • Nevena Baljosevic,
  • Sanja Zgradic,
  • Jasna El Mezeni and
  • Tamara Milovanovic
  • + 2 authors

9 November 2024

Background/Objectives: Alcohol can directly damage the liver, causing steatosis, steatohepatitis, cirrhosis, and hepatocellular cancer. The aim of this study was to examine 28-day survival in hospitalized patients with alcohol-related liver disease (...

  • Article
  • Open Access
14 Citations
5,311 Views
16 Pages

1 August 2023

With the rapid development of fingerprint recognition systems, fingerprint liveness detection is gradually becoming regarded as the main countermeasure to protect the fingerprint identification system from spoofing attacks. Convolutional neural netwo...

  • Article
  • Open Access
3,742 Views
12 Pages

6 July 2022

Patients with severe adolescent idiopathic scoliosis (AIS) require instrumented spinal fusion surgery. The range of instrumented vertebra is still questioned, especially the selection of the lowest instrumented vertebra (LIV). This single institution...

  • Article
  • Open Access
371 Views
14 Pages

24 December 2025

The Lorentz invariance violation (LIV) predicted by some quantum gravity theories would manifest as an energy-dependent speed of light, which may potentially distort the observed temporal profile of photons from astrophysical sources at cosmological...

  • Feature Paper
  • Article
  • Open Access
12 Citations
3,898 Views
10 Pages

Possible violations of Lorentz invariance (LIV) can produce vacuum birefringence, which results in a frequency-dependent rotation of the polarization plane of linearly polarized light from distant sources. In this paper, we try to search for a freque...

  • Article
  • Open Access
140 Views
15 Pages

25 February 2026

Background: Kyphotic deformity following osteoporotic vertebral fracture (KDOVF) often requires corrective surgery to restore sagittal alignment; however, mechanical complications, such as proximal junctional failure (PJF) and distal junctional failu...

  • Review
  • Open Access
3 Citations
2,810 Views
15 Pages

Testing Quantum Gravity in the Multi-Messenger Astronomy Era

  • Aleksandra Piórkowska-Kurpas and
  • Marek Biesiada

Quantum gravity (QG) remains elusive despite almost century-long efforts to combine general relativity and quantum mechanics. All the approaches triggered and powered by purely theoretical considerations eventually failed with a prevailing feeling of...

  • Article
  • Open Access
1 Citations
2,815 Views
10 Pages

26 June 2022

Most quantum gravity theories quantize space-time on the order of Planck length (p ). Some of these theories, such as loop quantum gravity (LQG), predict that this discreetness could be manifested through Lorentz invariance violations (LI...

  • Article
  • Open Access
13 Citations
5,379 Views
17 Pages

Exploring Acceptability Drivers of Oral Antibiotics in Children: Findings from an International Observational Study

  • Thibault Vallet,
  • Yahya Bensouda,
  • Jumpei Saito,
  • Liv Mathiesen,
  • Varsha Pokharkar,
  • Viviane Klingmann,
  • Matthew Peak,
  • Omar Elhamdaoui,
  • Akimasa Yamatani and
  • Fabrice Ruiz
  • + 7 authors

Antibiotics are among the most commonly prescribed drugs in children. Adherence to the treatment with these drugs is of the utmost importance to prevent the emergence of resistant bacteria, a global health threat. In children, medicine acceptability...

  • Article
  • Open Access
24 Citations
4,857 Views
15 Pages

Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction

  • Siv Boon Mundal,
  • Johanne Johnsen Rakner,
  • Gabriela Brettas Silva,
  • Lobke Marijn Gierman,
  • Marie Austdal,
  • Purusotam Basnet,
  • Mattijs Elschot,
  • Siril Skaret Bakke,
  • Jenny Ostrop and
  • Ann-Charlotte Iversen
  • + 4 authors

10 February 2022

Utero-placental development in pregnancy depends on direct maternal–fetal interaction in the uterine wall decidua. Abnormal uterine vascular remodeling preceding placental oxidative stress and placental dysfunction are associated with preeclamp...

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