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146 Results Found

  • Article
  • Open Access
494 Views
15 Pages

12 December 2025

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract, marked by persistent mucosal inflammation and structural damage. We evaluated the efficacy of HCB-5300 and HCB-5400, novel selective STAT3 allosteric i...

  • Article
  • Open Access
3 Citations
2,446 Views
15 Pages

19 July 2020

Hydroxymethyl carbon black (HCB) was prepared as an asphalt modifier with a high oxygen content and active surface chemical properties. The microstructure of HCB was analyzed by scanning electron microscopy, energy-dispersive X-ray spectroscopy, and...

  • Article
  • Open Access
4 Citations
2,638 Views
25 Pages

N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation

  • Eleonora Gianquinto,
  • Federica Sodano,
  • Barbara Rolando,
  • Magdalena Kostrzewa,
  • Marco Allarà,
  • Ali Mokhtar Mahmoud,
  • Poulami Kumar,
  • Francesca Spyrakis,
  • Alessia Ligresti and
  • Konstantin Chegaev

23 November 2022

Cannabinoid type 1 (hCB1) and type 2 (hCB2) receptors are pleiotropic and crucial targets whose signaling contributes to physiological homeostasis and its restoration after injury. Being predominantly expressed in peripheral tissues, hCB2R represents...

  • Article
  • Open Access
18 Citations
8,571 Views
13 Pages

Exposure to persistent environmental pollutants may constitute an important factor on the onset of a number of neurological disorders such as autism, Parkinson’s disease, and Attention Deficit Disorder (ADD), which have also been linked to reduced GA...

  • Article
  • Open Access
3 Citations
2,958 Views
15 Pages

Optimal Design Parameters for Hybrid DC Circuit Breakers Using a Multi-Objective Genetic Algorithm

  • Van-Vinh Nguyen,
  • Nhat-Tung Nguyen,
  • Quang-Thuan Nguyen,
  • Van-Hai Bui and
  • Wencong Su

25 August 2022

The primary function of hybrid direct current circuit breakers (HCBs) is to quickly interrupt fault currents to protect high-voltage direct current (HVDC) systems. To enhance the reliability and stability of HVDC systems, optimal design of HCBs is re...

  • Article
  • Open Access
11 Citations
3,391 Views
14 Pages

Mixture Effects of Polychlorinated Biphenyls (PCBs) and Three Organochlorine Pesticides on Cognitive Function in Mohawk Adults at Akwesasne

  • Nozomi Sasaki,
  • Laura E. Jones,
  • Gayle S. Morse,
  • David O. Carpenter and
  • on behalf of the Akwesasne Task Force on the Environment

The Mohawks at Akwesasne have been highly exposed to polychlorinated biphenyls (PCBs), via releases from three aluminum foundries located near the reserve. They are also exposed to organochlorine pesticides, namely hexachlorobenzene (HCB), dichlorodi...

  • Article
  • Open Access
115 Citations
8,274 Views
12 Pages

A Novel Hydrazinecarbothioamide as a Potential Corrosion Inhibitor for Mild Steel in HCl

  • Ahmed A. Al-Amiery,
  • Abdul Amir H. Kadhum,
  • Abu Bakar Mohamad and
  • Sutiana Junaedi

2 April 2013

2-(1-methyl-4-((E)-(2-methylbenzylidene)amino)-2-phenyl-1H-pyrazol-3(2H)-ylidene)-hydrazineecarbothioamide (HCB) was synthesized as a corrosion inhibitor from the reaction of 4-aminoantipyrine, thiosemicarbazide and 2-methylbenzaldehyde. The corrosio...

  • Article
  • Open Access
25 Citations
3,456 Views
21 Pages

Predicting Height to Crown Base of Larix olgensis in Northeast China Using UAV-LiDAR Data and Nonlinear Mixed Effects Models

  • Xin Liu,
  • Yuanshuo Hao,
  • Faris Rafi Almay Widagdo,
  • Longfei Xie,
  • Lihu Dong and
  • Fengri Li

8 May 2021

As a core content of forest management, the height to crown base (HCB) model can provide a theoretical basis for the study of forest growth and yield. In this study, 8364 trees of Larix olgensis within 118 sample plots from 11 sites were measured to...

  • Review
  • Open Access
12 Citations
3,285 Views
16 Pages

Nanoparticles for Mitigation of Harmful Cyanobacterial Blooms

  • Ilana N. Tseytlin,
  • Anna K. Antrim and
  • Ping Gong

12 January 2024

With the rapid advancement of nanotechnology and its widespread applications, increasing amounts of manufactured and natural nanoparticles (NPs) have been tested for their potential utilization in treating harmful cyanobacterial blooms (HCBs). NPs ca...

  • Article
  • Open Access
7 Citations
4,034 Views
18 Pages

Fenchone Derivatives as a Novel Class of CB2 Selective Ligands: Design, Synthesis, X-ray Structure and Therapeutic Potential

  • Reem Smoum,
  • Christeene Haj,
  • Shira Hirsch,
  • Alina Nemirovski,
  • Zhannah Yekhtin,
  • Benny Bogoslavsky,
  • Gaganjyot Kaur Bakshi,
  • Mukesh Chourasia,
  • Ruth Gallily and
  • Raphael Mechoulam
  • + 1 author

18 February 2022

A series of novel cannabinoid-type derivatives were synthesized by the coupling of (1S,4R)-(+) and (1R,4S)-(−)-fenchones with various resorcinols/phenols. The fenchone-resorcinol derivatives were fluorinated using Selectfluor and demethylated u...

  • Review
  • Open Access
1,142 Views
20 Pages

15 September 2025

HCBs (Harmful Cyanobacterial Blooms) are increasing in freshwaters across the globe, particularly at lower latitudes. In Southern Europe, a decrease in annual precipitation and an increase in drought periods have enhanced the occurrence of HCBs, impa...

  • Article
  • Open Access
80 Citations
7,484 Views
13 Pages

Placental Transfer of Persistent Organic Pollutants: A Preliminary Study on Mother-Newborn Pairs

  • Maria Grazia Porpora,
  • Renato Lucchini,
  • Annalisa Abballe,
  • Anna Maria Ingelido,
  • Silvia Valentini,
  • Eliana Fuggetta,
  • Veronica Cardi,
  • Adele Ticino,
  • Valentina Marra and
  • Elena De Felip
  • + 1 author

The aim of this study was to characterize the placental transfer of some environmental pollutants, and to explore the possibility of quantitatively predicting in utero exposure to these contaminants from concentrations assessed in maternal blood. Lev...

  • Article
  • Open Access
467 Views
19 Pages

Modelling the Transference of Paediatric Patients with Inborn Errors of Metabolism to Adult Hospitals: Clinical Experience

  • Aida Deudero,
  • Esther Lasheras,
  • Roser Ventura,
  • Cristina Montserrat-Carbonell,
  • José César Milisenda,
  • Natalia Juliá-Palacios,
  • Ana Matas,
  • María de Talló Forga-Visa,
  • Rosa María López-Galera and
  • IEM-SJD-HCB Consortia
  • + 9 authors

22 December 2025

Background/Objectives: Inborn errors of metabolism (IEM) are chronic, life-threatening genetic disorders with a significant cumulative prevalence worldwide. Advances in early diagnosis and treatment have significantly increased life expectancy, under...

  • Review
  • Open Access
13 Citations
7,249 Views
20 Pages

Under the Climate Change scenario, the occurrence of Harmful Cyanobacterial Blooms (HCBs) is an increasingly concerning problem. Particularly for inland freshwaters, that have human populations depending on them for consumption or recreation, HCBs ca...

  • Article
  • Open Access
23 Citations
4,444 Views
26 Pages

Multi-Person Tracking and Crowd Behavior Detection via Particles Gradient Motion Descriptor and Improved Entropy Classifier

  • Faisal Abdullah,
  • Yazeed Yasin Ghadi,
  • Munkhjargal Gochoo,
  • Ahmad Jalal and
  • Kibum Kim

18 May 2021

To prevent disasters and to control and supervise crowds, automated video surveillance has become indispensable. In today’s complex and crowded environments, manual surveillance and monitoring systems are inefficient, labor intensive, and unwieldy. A...

  • Abstract
  • Open Access
1,066 Views
1 Page

Eutrophication became the main environmental problem of Azorean lakes at the end of the 20th century, resulting mainly from the intensification of anthropogenic activities in the catchments. This problem raised great public concern, leading to the im...

  • Article
  • Open Access
5 Citations
4,713 Views
16 Pages

A Cocktail of Plankton and Organochlorines for Whale Shark in the Foraging Areas of Nosy Be (Madagascar)

  • Letizia Marsili,
  • Guia Consales,
  • Patrizia Romano,
  • Rachele Rosai,
  • Paolo Bava,
  • Francesca Romana Reinero and
  • Primo Micarelli

4 August 2023

Seas and oceans are contaminated by persistent organic pollutants (POPs), which are released into the environment by human activities. The chemical-physical properties of POPs induce high persistence and toxicity in marine organisms from the lowest t...

  • Article
  • Open Access
5 Citations
4,415 Views
11 Pages

3 November 2022

The ditopic molecule 3-(1,3,5-trimethyl-1H-4-pyrazolyl)pentane-2,4-dione (HacacMePz) combines two different Lewis basic sites. It forms a crystalline adduct with the popular halogen bond (XB) donor 2,3,5,6-tetrafluoro-1,4-diiodobenzene (TFDIB) with a...

  • Feature Paper
  • Article
  • Open Access
18 Citations
5,353 Views
15 Pages

In response to the irreversible aging trend, the Taiwan government has promoted the Long-Term Care (LTC) policy 1.0 launched in 2007 and the LTC policy 2.0 reform since 2016. This study aimed to explore the utilization of formal home and community-ba...

  • Review
  • Open Access
2 Citations
1,645 Views
21 Pages

17 February 2025

Climate change is promoting the occurrence of Harmful Cyanobacterial Blooms (HCBs) across freshwaters, posing serious risks for the ecosystems and human health. Under these warmer conditions, particularly blooms of invasive Aphanizomenon-like species...

  • Abstract
  • Open Access
1,819 Views
2 Pages

Climate change enhances the occurrence of HCBs (Harmful Cyanobacterial Blooms) worldwide, particularly in freshwater ecosystems, posing increased risks for local populations. The present work intends to conduct a spatiotemporal historical overview on...

  • Article
  • Open Access
1,026 Views
16 Pages

Access to home- and community-based services (HCBSs) varies substantially between states. Yet, it is unknown how state-level policies and administrative factors impact consumer-reported unmet service needs, an important indicator of HCBS access and q...

  • Article
  • Open Access
23 Citations
5,802 Views
22 Pages

Prediction of Individual Tree Diameter and Height to Crown Base Using Nonlinear Simultaneous Regression and Airborne LiDAR Data

  • Zhaohui Yang,
  • Qingwang Liu,
  • Peng Luo,
  • Qiaolin Ye,
  • Guangshuang Duan,
  • Ram P. Sharma,
  • Huiru Zhang,
  • Guangxing Wang and
  • Liyong Fu

13 July 2020

The forest growth and yield models, which are used as important decision-support tools in forest management, are commonly based on the individual tree characteristics, such as diameter at breast height (DBH), crown ratio, and height to crown base (HC...

  • Article
  • Open Access
21 Citations
4,580 Views
17 Pages

Development of Crown Ratio and Height to Crown Base Models for Masson Pine in Southern China

  • Yao Li,
  • Wei Wang,
  • Weisheng Zeng,
  • Jianjun Wang and
  • Jinghui Meng

19 November 2020

Crown ratio (CR) and height to crown base (HCB) are important crown characteristics influencing the behavior of forest canopy fires. However, the labor-intensive and costly measurement of CR and HCB have hindered their wide application to forest fire...

  • Article
  • Open Access
5 Citations
5,213 Views
15 Pages

6 October 2018

The eventual goal of high-voltage direct-voltage (HVDC) systems is to implement HVDC grids. The modular multilevel converter (MMC) has been identified as the best candidate for the realization of an HVDC grid by eliminating the shortcomings of conven...

  • Article
  • Open Access
1 Citations
1,618 Views
22 Pages

Acute Toxicity of Carbon Nanotubes, Carbon Nanodots, and Cell-Penetrating Peptides to Freshwater Cyanobacteria

  • Anna K. Antrim,
  • Ilana N. Tseytlin,
  • Emily G. Cooley,
  • P. U. Ashvin Iresh Fernando,
  • Natalie D. Barker,
  • Erik M. Alberts,
  • Johanna Jernberg,
  • Gilbert K. Kosgei and
  • Ping Gong

1 April 2025

Synthetic non-metallic nanoparticles (NMNPs) such as carbon nanotubes (CNTs), carbon nanodots (CNDs), and cell-penetrating peptides (CPPs) have been explored to treat harmful algal blooms. However, their strain-specific algicidal activities have been...

  • Article
  • Open Access
5 Citations
3,807 Views
12 Pages

11 November 2021

Habitat conservation banking is a policy instrument for conserving endangered species by providing financial incentives for the landowners in the United States. This policy instrument aims to protect habitat, but little or no thought has been given t...

  • Article
  • Open Access
1,076 Views
22 Pages

Associations of Place-Based Factors with Service Use and Consumer-Reported Unmet Service Needs Among Older Adults Using Publicly Funded Home- and Community-Based Services in the United States

  • Tetyana P. Shippee,
  • Romil R. Parikh,
  • Nicholas Musinguzi,
  • Benjamin W. Langworthy,
  • Jack M. Wolf,
  • Stephanie Giordano and
  • Eric Jutkowitz

Access to home- and community-based services (HCBS) is critical for aging in place; yet many older adults continue to experience unmet needs. While individual-level factors are better-studied, less is known about how neighborhood-level place-based fa...

  • Article
  • Open Access
1,503 Views
12 Pages

8 October 2024

Hexachlorobenzene (HCB) is one of the most persistent environmental pollutants of global concern. Ni/Fe nanoparticles, with their small particle size, large surface area, and high reactivity, are a promising candidate for HCB degradation. In this wor...

  • Article
  • Open Access
1,160 Views
18 Pages

The Preparation and Characterization of Antioxidant Films Based on Hazelnut Shell-Based Vegetable Carbon Black/Chitosan/Gelatin and the Application on Soybean Oils

  • Mengyuan Niu,
  • Jiaxin Wang,
  • Zhaoying Xun,
  • Mengzhuo Liu,
  • He Li,
  • Weiyi Wang,
  • Yuchen Wang,
  • Chao Guo,
  • Hanyu Li and
  • Ning Xia
  • + 2 authors

9 May 2025

In this study, hazelnut shell-based vegetable carbon black (HCB) was synthesized from renewable agricultural waste and incorporated into chitosan (CS) and gelatin (GEL) matrices to fabricate active packaging films. The structure of HCB was characteri...

  • Article
  • Open Access
1,125 Views
14 Pages

30 November 2024

Hexachlorobenzene (HCB) is a persistent organic pollutant (POP) commonly detected in milk and dairy products. These compounds pose a serious threat to the health of consumers due to their considerable bioaccumulation potential, high stability, and to...

  • Article
  • Open Access
3 Citations
2,205 Views
14 Pages

21 January 2024

(1) Background: Hexachlorobenzene (HCB) is a persistent organic pollutant that is possibly carcinogenic to humans. It is still found in the environment, humans and animals, and in foods, including milk and dairy products; (2) Methods: The influence o...

  • Article
  • Open Access
3 Citations
1,742 Views
26 Pages

Revealing the Mechanism of Hemerocallis citrina Baroni in Depression Treatment Through Integrated Network Pharmacology and Transcriptomic Analysis

  • Shan Gao,
  • Jihui Lu,
  • Yixiao Gu,
  • Yaozhi Zhang,
  • Cheng Wang,
  • Feng Gao,
  • Ziqi Dai,
  • Shujing Xu,
  • Jindong Zhang and
  • Haimin Lei
  • + 1 author

17 December 2024

Background/Objectives: Hemerocallis citrina Baroni (HCB) is a traditional herb for the treatment of depression in China. However, the active constituents and the underlying mechanisms of its antidepressant effects remain unclear. The aim of this stud...

  • Feature Paper
  • Article
  • Open Access
45 Citations
15,160 Views
25 Pages

Semiconductor Devices in Solid-State/Hybrid Circuit Breakers: Current Status and Future Trends

  • Chunyang Gu,
  • Pat Wheeler,
  • Alberto Castellazzi,
  • Alan J. Watson and
  • Francis Effah

6 April 2017

Circuit breakers (CBs) are the main protection devices for both alternating current (AC) and direct current (DC) power systems, ranging from tens of watts up to megawatts. This paper reviews the current status for solid-state circuit breakers (SSCBs)...

  • Article
  • Open Access
31 Citations
7,585 Views
12 Pages

Variation in Older Adult Characteristics by Residence Type and Use of Home- and Community-Based Services

  • Heidi H. Ewen,
  • Tiffany R. Washington,
  • Kerstin G. Emerson,
  • Andrew T. Carswell and
  • Matthew Lee Smith

Background: The majority of older adults prefer to remain in their homes, or to “age-in-place.” To accomplish this goal, many older adults will rely upon home- and community-based services (HCBS) for support. However, the availability and accessibili...

  • Article
  • Open Access
3,323 Views
12 Pages

Long-Term Behavior of RC Beams Strengthened with Hybrid Composite Beam

  • IL-Heon Kim,
  • Hyung-Joo Lee,
  • Joo-Won Kang and
  • Yeol Choi

26 April 2019

This paper describes the results of long-term tests on reinforced concrete (RC) beams strengthened with hybrid composite beam (HCB) under two different sustained loads. Test specimens were fabricated to reflect the most common RC beam size used in sc...

  • Article
  • Open Access
10 Citations
2,440 Views
23 Pages

19 January 2022

Individual trees are characterized by various sizes and forms, such as diameter at breast height, total height (H), height to crown base (HCB), crown length (CL), crown width, and crown and stem forms. Tree characteristics are strongly related to eac...

  • Article
  • Open Access
14 Citations
3,999 Views
13 Pages

4-hydroxycyanobenzene (4HCB) is a dipolar molecule formed of an aromatic substituted benzene ring with the CN and OH functional groups at the 1 and 4 positions. In the crystalline state, it forms spiral chains via hydrogen bonding, which pack togethe...

  • Article
  • Open Access
9 Citations
2,576 Views
15 Pages

25 May 2022

Height to crown base (HCB) is an important variable used as a predictor of forest growth and yield. This study developed a nonlinear, mixed-effects HCB model through inclusion of plot-level random effects using data from 29 sample plots distributed a...

  • Article
  • Open Access
11 Citations
2,449 Views
25 Pages

25 November 2022

In this study, we evaluate the long-term and seasonal variations of polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB), α-, γ-hexachlorocyclohexanes (HCH), and p,p′-dichlorodiphenyltrichloroethane (p,p′-DDT) and its met...

  • Article
  • Open Access
17 Citations
5,631 Views
13 Pages

Hexachlorobenzene (HCB) contamination of soils remains a significant environmental challenge all over the world. Reductive stabilization is a developing technology that can decompose the HCB with a dechlorination process. A nanometallic Al/CaO (n-Al/...

  • Article
  • Open Access
13 Citations
3,417 Views
10 Pages

In this work, carbonated hydroxyapatite/titanium alloy (CHA/Ti) and carbonated hydroxyapatite/honeycomb/titanium alloy (CHA/HCB/Ti) plates were coated using the electrophoretic deposition dip coating (EP2D) method. Analysis of cell viability and surf...

  • Article
  • Open Access
12 Citations
3,560 Views
18 Pages

20 December 2022

Mitigating cyanotoxin production is essential to protecting aquatic ecosystems and public health. However, current harmful cyanobacterial bloom (HCB) control strategies have significant shortcomings. Because predicting HCBs is difficult, current HCB...

  • Feature Paper
  • Article
  • Open Access
5 Citations
2,323 Views
10 Pages

16 February 2023

The fate of chemical pollutants in the environment is determined by various factors including the type and strength of their interactions with reactive surfaces in soils and sediments. In the present work the interactions of hexachlorobenzene (HCB) w...

  • Article
  • Open Access
5 Citations
1,726 Views
15 Pages

11 August 2023

Castanopsis hystrix, a timber resource from Southeast Asia, is characterized by rapid growth and high yield, but plantation quality and efficiency improvements are required. Twenty-year-old C. hystrix experimental forests in Yulin, Liuzhou, and Pingx...

  • Article
  • Open Access
2 Citations
1,689 Views
21 Pages

4 November 2024

This study compared hierarchical Bayesian, mixed-effects Gaussian process regression, and random forest models for predicting height to crown base (HCB) in Qinghai spruce (Picea crassifolia Kom.) forests using LiDAR-derived data. Both modeling approa...

  • Article
  • Open Access
8 Citations
3,774 Views
26 Pages

The Contest of Nanoparticles: Searching for the Most Effective Topical Delivery of Corticosteroids

  • Aneta Kalvodová,
  • Kristýna Dvořáková,
  • Eliška Petrová,
  • Bozena B. Michniak-Kohn and
  • Jarmila Zbytovská

Owing to their complicated pathophysiology, the treatment of skin diseases necessitates a complex approach. Conventional treatment using topical corticosteroids often results in low effectiveness and the incidence of local or even systemic side effec...

  • Article
  • Open Access
7 Citations
2,817 Views
30 Pages

15 November 2022

The effects of various parameter interactions on the textural structure of hydrochars produced via hydrothermal (HTC) and co-hydrothermal (Co-HTC) treatments of coal discards and sewage sludge (wastes), as well as the subsequent use of the hydrochars...

  • Article
  • Open Access
11 Citations
6,976 Views
23 Pages

In hot and humid climatic conditions, cooling tends to dominate building thermal energy use. Cooling loads can be reduced through the adoption of efficient building envelope materials, such as Structural Insulated Panels (SIPs). This study quantifies...

  • Feature Paper
  • Article
  • Open Access
7 Citations
2,819 Views
22 Pages

6 August 2021

Harmful cyanobacteria blooms (HCBs) are one of the main water quality threats affecting reservoirs. Guidelines suggest integrating laboratory, real-time in situ, and remote sensing data in the monitoring of HCBs. However, this approach is still littl...

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