97 Results Found

Jupiter’s moon Europa harbors one of the most likely environments for extant extraterrestrial life. Determining whether Europa is truly habitable requires understanding the structure and thickness of its ice shell, including the existence of pe...

A Ganymede-synchronous frozen orbit around Europa provides a stable spatial geometry between a Europa probe and a Ganymede lander, which facilitates the observation of Ganymede and data transmission between probes. However, the third-body gravitation...

There has been remarkable progress in identifying a certain type of biosignature, both from the point of view of the payloads of forthcoming missions, and from the point of view of biogeochemistry. This progress has been due to the evolution of minia...

This paper presents the reconstruction framework of the Roman mosaic with the central scene from the abduction of Europa. The mosaic depicting Europa, discovered in Ptuj (Slovenia) and dated from the second half of the third to the beginning of the f...

Enceladus and Europa, icy moons of Saturn and Jupiter, respectively, are believed to be habitable with liquid water oceans and therefore are of interest for future life detection missions and mission concepts. With the limited data from missions to t...

This study introduces an innovative in situ lander/impact-penetrator design tailored for Discovery-class missions to Europa, specifically focused on conducting astrobiological analyses. The platform integrates a microfluidic capacitively coupled cont...

Film adaptations invariably yield insights into their written source material, at least to the extent that they elect to translate or omit what may be deemed the literature’s essential components. This is certainly the case for director Agnieszka Hol...

The search for life in the universe is often informed by the study of “extreme” environments on Earth, which provide analogs for habitable locations in the Solar System, and whose microbial inhabitants may therefore also serve as analogs...

Europa has been spotted as having water outgassing activities by space- and ground-based telescopes as well as reanalysis of the Galileo data. We adopt a 3D Direct Simulation Monte Carlo (DSMC) model to investigate the observed plume characteristics...

We briefly present preliminary results of our study of the radioresistant bacteria in a low temperature and pressure and high-radiation environment and hypothesize the ability of microorganisms to survive extraterrestrial high-radiation environments,...

Qualifying for European competitions allows football clubs to have access to the two most important football competitions played in Europe, UEFA Champions League and UEFA Europa League. Thereby, participation in these important competitions has both...

Robots have become a popular educational tool in secondary education, introducing scientific, technological, engineering and mathematical concepts to students all around the globe. In this paper EUROPA, an extensible, open software and open hardware...

Purpose: This article presents data challenging the widely held but untested view that concurrently playing mid-week Union of European Football Associations (UEFA) Europa League matches adversely affects domestic league performance. Method: Over 16 s...

We perform quantitative studies of the growth, death, and gene expression of Escherichia coli in a wide range of magnesium sulfate (MgSO 4 ) concentrations (0–2.5 M). Elevated concentration of MgSO 4 causes the inhibition of cell...

In this work, we investigate the behavior of low-energy trajectories in the dynamical framework of the spatial elliptic restricted 4-body problem, developed using the Hamiltonian formalism. Introducing canonical transformations, the Hamiltonian funct...

Fertilization and mowing affects the physico-chemical properties of soils, as well as the characteristics of the plants growing on them. Changes in the management techniques are causing semi-natural grasslands to disappear all over Europe. These gras...

National Parks are spaces that are of great interest for evaluating and monitoring global environmental change as these parks encompass natural, cultural, and rural features, along with ecological processes, which are subject to social or economic ch...

Sodium and sulfate ions are among the suggested abundant ions on Europa, a moon of Jupiter. In order to investigate the potential habitability of Europa, we study the effects of sodium sulfate (Na2SO4) on a non-halophilic bacterium by subjecting Esch...

Two anhydrobiotic strains of the cyanobacterium Chroococcidiopsis, namely CCMEE 029 and CCMEE 171, isolated from the Negev Desert in Israel and from the Dry Valleys in Antarctica, were exposed to salty-ice simulations. The aim of the experiment was t...

Background: The efficacy of therapy for coronary heart disease with ACE inhibitors has been documented in clinical investigations. The EUROPA study has backed up the clinical usefulness of the ACE inhibitor perindopril in a dose of 8 mg/day in patien...

Some of the icy moons of the solar system with a subsurface ocean, such as Europa and Enceladus, are the targets of future space missions that search for potential extraterrestrial life forms. While the ice shells that envelop these moons have been s...

This study perceives professional European football as one of the most relevant event-related entrepreneurial ecosystems (EEs) worldwide. It also identifies a healthy sporting competition in the five most popular European football leagues (Spain, Eng...

A Planetary Atmospheric Chamber (PAC) was used to create simulations of interplanetary conditions to test the spore survival of three Bacillus spp. exposed to interacting conditions of vacuum (VAC), simulated solar heating (HEAT), and simulated solar...

Debris cones are a very common landform in temperate high mountains. They are the most representative examples of the periglacial and nival processes. This work studies the dynamic behavior of two debris cones (Cone A and Cone B) in the Picos de Euro...

C-phycoerythrin (C-PE) is a phycobiliprotein that prevents oxidative stress and cell damage. The aim of this study was to evaluate whether C-PE also counteracts endoplasmic reticulum (ER) stress as a mechanism contributing to its nephroprotective act...

Equine placentitis is characterized by infection and inflammation of the placenta. Different biomarkers associated with this inflammatory response have been evaluated in experimentally induced equine placentitis, but not in pregnant mares with sponta...

Deoxynivalenol (DON) is a major mycotoxin present in animal feed and negatively affects growth and reproduction in farm species, including pigs and cattle. The mechanism of DON action involves the ribotoxic stress response (RSR), and it acts directly...

Chronic kidney disease (CKD) is a burden in low- and middle-income countries, and a late diagnosis with systemic arterial hypertension (SAH) is the major complication of CKD. C-phycoerythrin (CPE) is a bioactive compound derived from Phormidium persi...

Melanoma is the most aggressive and deadly form of skin cancer, and its incidence has been steadily increasing over the past few decades, particularly in the Caucasian population. Immune checkpoint inhibitors (ICI), anti-PD-1 monotherapy or in combin...

This work shows the experiences acquired by the experimental test performed to validate an automated peritoneal dialysis machine using rabbits with kidney damage to find improvements that can be made for future advances. These are listed to understan...

Background/Objectives: Potency testing of clinical-grade lentiviral vectors (LVVs) is critical to support a drug’s commercial approval. Careful consideration should be paid to the development of a suitable potency test during the drug’s c...

C-phycocyanin (CPC) is an antioxidant protein that, when purified, is photosensitive and can be affected by environmental and gastrointestinal conditions. This can impact its biological activity, requiring an increase in the effective amount to achie...

The immune system is a dynamic feature of each individual and a footprint of our unique internal and external exposures. Indeed, the type and level of exposure to physical and biological agents shape the development and behavior of this complex and d...

C-phycocyanin (CPC) is an antihypertensive that is not still wholly pharmacologically described. The aim of this study was to evaluate whether CPC counteracts endothelial dysfunction as an antihypertensive mechanism in rats with 5/6 nephrectomy (NFx)...

T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) is a rare, aggressive subtype of diffuse large B-cell lymphoma characterized by a profoundly immunosuppressive tumor microenvironment. PD-L1 overexpression by tumor cells is a recognized immune e...

Asthma is a chronic immunological disease related to oxidative stress and chronic inflammation; both processes promote airway remodeling with collagen deposition and matrix thickening, causing pulmonary damage and lost function. This study investigat...

The treatment landscape for advanced melanoma has transformed significantly with the advent of BRAF and MEK inhibitors (BRAF/MEKi) targeting BRAFV600 mutations, as well as immune checkpoint inhibitors (ICI) like anti-PD-1 monotherapy or its combinati...

Background/Objectives: Cerebral ischemia and reperfusion injury, induced by bilateral common carotid artery occlusion and reperfusion (BCCAO/R), cause extensive neuronal damage and cognitive impairment. Bouvardia ternifolia (BtD), a plant known for i...

Background: Immune checkpoint inhibitors (ICIs) targeting PD-1 have significantly improved outcomes in patients with advanced melanoma. However, the optimal treatment duration remains undefined. Circulating tumor DNA (ctDNA) has emerged as a promisin...

Given the economical importance of the olive tree it is essential to study its responses to stress agents such as excessive UV-B radiation, to understand the defense mechanisms and to identify the varieties that are able to cope with it. In the light...

With the discovery of the persistent jets of water being ejected to space from Enceladus, an understanding of the effect of the space environment on potential organisms and biosignatures in them is necessary for planning life detection missions. We e...

Two widely-cited alternative hypotheses propose geological localities and biochemical mechanisms for life’s origins. The first states that chemical energy available in submarine hydrothermal vents supported the formation of organic compounds an...

We have found 117 taxa of lichenicolous fungi in the studied area. In this paper, we describe five taxa: Arthonia boomiana on Nephromopsis chlorophylla, Lawalreea burgaziana on Platismatia glauca, Pronectria scrobiculatae on Lobarina scrobiculata, Tr...

Beginning in late 2017, highly pathogenic avian influenza (HPAI) H5N6 viruses caused outbreaks in wild birds and poultry in several European countries. H5N6 viruses were detected in 43 wild birds found dead throughout Denmark. Most of the Danish viru...

Digital holographic microscopy provides the ability to observe throughout a volume that is large compared to its resolution without the need to actively refocus to capture the entire volume. This enables simultaneous observations of large numbers of...

To achieve the goals of reducing building energy consumption, regulations are being designed to guarantee the appropriate energy performance of buildings. Both European and South American countries establish requirements of thermal properties of buil...

This study presents the development of an innovative drop-stain-coat fabrication technique for creating high-quality PEDOT:PSS films, optimized for use in polymer-based electrodes within contactless conductivity detection (C4D) sensors. We detail the...

Subsurface exploration of ice-covered planets and moons presents communications challenges because of the need to communicate through kilometers of ice. The objective of this task is to develop the capability to wirelessly communicate through kilomet...

In the last decades, substantial changes have occurred regarding what scientists consider the limits of habitable environmental conditions. For every extreme environmental condition investigated, a variety of microorganisms have shown that not only c...

The current interest in ice caves requires that their varied manifestations be known as accurately as possible in view of their responses to a global change and also to their great potential as paleoenvironmental witnesses. This phenomenon has been k...